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Preparation method of liuwei eyesight improving pharmaceutical composition

A composition and medicine technology, applied in the field of preparation of Liuwei Mingmu pharmaceutical compositions, can solve the problems of slow release of active ingredients of raw medicines, affecting the absorption and utilization of active ingredients of medicines, etc. quick effect

Active Publication Date: 2013-08-07
JINKE TIBETAN MEDICINE QINGHAI PROV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, in the prior art, the preparation methods of Liuwei improving eyesight drugs all adopt simple physical treatment of crushing and mixing the raw materials, and the active ingredients of the raw materials are released slowly, which seriously affects the absorption and utilization of the active ingredients of the drug, and eye diseases are more likely to affect Therefore, it is of great significance to provide Liuwei Mingmu preparations with rapid dissolution, onset of effect, better absorption and utilization

Method used

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  • Preparation method of liuwei eyesight improving pharmaceutical composition
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  • Preparation method of liuwei eyesight improving pharmaceutical composition

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] The proportioning by weight of the crude drug of embodiment 1 pharmaceutical composition is as follows:

[0033] Iron powder 111g, barberry bark 111g, Tibetan fennel 111g, myrobalan 56g, myrobalan 56g, emblica 56g.

[0034] The commercially available Liuwei Mingmu Pill used as a comparison is the product of Qinghai Jinhe Tibetan Medicine Pharmaceutical Co., Ltd.

[0035] Embodiment 1, the preparation of a kind of Liuwei improving eyesight medicinal composition capsule

[0036](1) Take 111g of Tibetan fennel according to the composition ratio of raw materials, add 666g of water, use steam distillation, extract the volatile oil for 4 hours, collect the volatile oil, and obtain 2.70ml; filter the medicinal liquid to obtain the extract A' and medicinal residue A";

[0037] Add the collected volatile oil into 6% β-cyclodextrin aqueous solution by weight and volume, the volume-to-weight ratio of volatile oil to β-cyclodextrin is 1ml: 6g, keep the temperature at 50°C under st...

Embodiment 2

[0040] Embodiment 2, the preparation of a kind of Liuwei improving eyesight medicinal composition granule

[0041] (1) Take 111g of Tibetan fennel according to the composition ratio of raw materials, add 666g of water, use steam distillation, extract the volatile oil for 4 hours, collect the volatile oil, and obtain 2.70ml; filter the medicinal liquid to obtain the extract A' and medicinal residue A";

[0042] Add the collected volatile oil into 6% β-cyclodextrin aqueous solution by weight volume percentage, the volume-to-weight ratio of volatile oil to β-cyclodextrin is 1ml:7g, keep the temperature at 55°C under stirring conditions, ultrasonically treat for 4h, and Power 200W, frequency 40kHz; refrigerate overnight at 2°C, filter with suction, precipitate, and dry under vacuum at 50°C to obtain clathrate A of volatile oil;

[0043] (2) Take 111g of iron powder, 111g of barberry bark, 56g of myrobalan, 56g of myrobalan, and 56g of emblica according to the proportioning ratio o...

Embodiment 3

[0045] Embodiment 3, the preparation of a kind of Liuwei improving eyesight pharmaceutical composition tablet

[0046] (1) Take 111g of Tibetan fennel according to the composition ratio of the raw material medicine, add 666g of water, use steam distillation, extract the volatile oil for 5 hours, collect the volatile oil, and obtain 2.76ml; filter the medicinal liquid to obtain the extract A' and the medicinal residue A";

[0047] Add the collected volatile oil into 6% β-cyclodextrin aqueous solution by weight and volume, the volume-to-weight ratio of volatile oil to β-cyclodextrin is 1ml: 6g, keep the temperature at 50°C under stirring conditions, ultrasonically treat for 4h, and Power 200W, frequency 40kHz; refrigerate overnight at 2°C, filter with suction, precipitate, and dry under vacuum at 50°C to obtain clathrate A of volatile oil;

[0048] (2) Take 111g of iron powder, 111g of barberry bark, 56g of myrobalan, 56g of myrobalan, and 56g of emblica according to the proport...

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Abstract

The invention relates to a preparation method of liuwei eyesight improving pharmaceutical composition. The method comprises the steps of extraction and inclusion of volatile oil, water extraction, preparation forming and the like. Compared with traditional preparations, the preparation of the invention obviously improves patient compliance. The pharmaceutical preparation prepared by the method provided by the invention is characterized in that absorption is fast, effective components concentrate on focus positions, effect is quick and bioavailability is high under the premise that the original preparation drug effect is reserved. The efficacy of the pharmaceutical preparation prepared by the method provided by the invention is improved.

Description

technical field [0001] The invention relates to a preparation method of a pharmaceutical composition, in particular to a preparation method of a Liuwei improving eyesight medicinal composition. Background technique [0002] The liver resuscitates the eyes, which is a common view of traditional Chinese medicine and Tibetan medicine. Tibetan medicine believes that the liver is connected with the eyes, and the vision of the eyes will be normal if the eyes are nourished with liver blood. If the liver fire is inflamed, there will be symptoms such as red eyes, swelling, pain, shame and tears, and blurred vision. Therefore, for red eyes, swelling and pain caused by liver fire, clearing liver fire and improving eyesight are the fundamental treatment. [0003] Liuwei Mingmu Pill is an exclusive product of Jinhe Tibetan Medicine Pharmaceutical Co., Ltd. The original standard is recorded in the National Compilation of Chinese Patent Medicine Standards Ophthalmology, Otolaryngology, a...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/127A61K36/47A61K47/40A61P27/02
Inventor 陈芹丽赵丽丽李晗宋洋杨文钰郑亭亭魏艳芸
Owner JINKE TIBETAN MEDICINE QINGHAI PROV
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