772 results about "Muscle strength" patented technology

The present invention provides compositions and methods which involve specifically antagonizing GDF8 and Activin A. In certain embodiments, compositions are provided which comprise a GDF8-specific binding protein and an Activin A-specific binding protein. For example, the invention includes compositions comprising an anti-GDF8 antibody and an anti-Activin A antibody. In other embodiments, antigen-binding molecules are provided which comprise a GDF8-specific binding domain and an Activin A-specific binding domain. For example, the invention includes bispecific antibodies that bind GDF8 and Activin A. The compositions of the present invention are useful for the treatment of diseases and conditions characterized by reduced muscle mass or strength, as well as other conditions which are treatable by antagonizing GDF8 and / or Activin A activity.

A dietary supplement is provided that comprises creatine combined with ginseng and astragalus and, optionally, glutamine. The dietary supplement enhances the general energy boost and muscular strength increase achieved from the consumption of creatine alone.

The present invention provides a method capable of acquiring a physically and physiologically valid muscular strength from motion data based on a musculoskeletal model. The present invention relates to a method for obtaining muscular tension by performing inverse dynamics calculation of a musculoskeletal model. The method comprises a step for optimizing a contact force τC received from an environment using acquired floor reaction force data and a step for optimizing the muscle tension ƒ using acquired motion data, acquired myogenic potential data, and optimized contact force. The motion data, reaction force data and myogenic potential data can be measured at the same time by a behavior capture system.

The present invention provides a collapsible exercise apparatus, generally comprising a riser assembly, a carriage assembly, riser assembly support means, and peripheral attachments. The riser assembly further comprises a pair of parallel riser members and the carriage assembly further comprises a riser-engaging end. The riser-engaging end is received between the riser members in a carriage assembly-receiving track. The user may thus selectively incline the carriage assembly in the carriage assembly-receiving track in this operational state for exerting muscular effort against varying degrees of the user's own body weight resistance to achieve some level of physical activity or as part of an otherwise regular exercise regimen. To enable easy horizontal transferability, for example, during shipping or when not in use, the carriage assembly is easily nested within the carriage assembly-receiving track. Additionally, no tools are required to assemble or collapse the exercise apparatus.

Exercise apparatus and method with selectively variable stabilization enabling a user to progressively increase his / her core body muscular strength. In various embodiments, the exercise apparatus includes a resistance cabling system providing a user defined line of motion, and a partial stabilizer pad being adjustably positionable offset from the line of motion, wherein the user's core body is positionable against the pad and required to resist the torque created by the offset. The user can progressively increase the distance between the line of motion and partial stabilizer pad, in order to progressively increase the force which the user's core body must resist to maintain an upright stature. In this way, the user can progressively, over time, increase his or her core body strength. A vertically and rotatably adjustable handle / arm assembly, resistance cabling and pulley assembly, and an overall exercise apparatus having a relatively small footprint but allowing multiple variable exercise routines, are also provided.

A system and method are presented to provide assist to a user by means of an exoskeleton with a controller capable of making the exoskeleton display active impedance. The exoskeleton assists the user by reducing the muscle effort required by the user to move his or her extremities. In one embodiment, a single-degree-of-freedom (1-DOF) exoskeleton assists a user with single-joint movement using an active impedance controller. In another embodiment, a multiple-degree-of-freedom (multi-DOF) exoskeleton assists a user with multiple-joint movement using an active impedance controller.

Exercise apparatus and method with selectively variable stabilization enabling a user to progressively increase his / her core body muscular strength. In various embodiments, the exercise apparatus includes a resistance cabling system providing a user defined line of motion, and a partial stabilizer pad being adjustably positionable offset from the line of motion, wherein the user's core body is positionable against the pad and required to resist the torque created by the offset. The user can progressively increase the distance between the line of motion and partial stabilizer pad, in order to progressively increase the force which the user's core body must resist to maintain an upright stature. In this way, the user can progressively, over time, increase his or her core body strength. A vertically and rotatably adjustable handle / arm assembly, resistance cabling and pulley assembly, and an overall exercise apparatus having a relatively small footprint but allowing multiple variable exercise routines, are also provided.

The invention discloses a lower limb rehabilitation robot compliance control method based on variable admittance. The control method comprises the following contents of synchronously acquiring surfaceelectromyogram signals and motion information of an uninjured side lower limb and an affected side lower limb of a patient via a Delsys electromyogram acquisition system and motion capture equipment,in cooperation with a plantar pressure sensor, acquiring human-machine interaction force between a lower limb rehabilitation robot and the patient via a plantar pressure sensor, and acquiring lower limb motion intentions of the patient through information fusion; establishing a human body lower limb musculoskeletal model via OpenSim software, calculating out muscle strength values of related muscles of lower limb flexion and extension motions, and in combination with an affected side mirroring uninjured side method as well as a GS-LSELM algorithm, establishing an electromyogram-muscle strength identification model of the human body lower limb and identifying out a muscle strength value of the affected side lower limb; and establishing a variable admittance model based on muscle strength torque and deviation away from an expected joint trajectory of the lower limb rehabilitation robot so as to correct the expected trajectory, and calculating deviation in combination with an actual trajectory and inputting the deviation into a position controller, so as to finally achieve tracking of the expected trajectory of the patient and active compliance control of the lower limb rehabilitation robot.

The invention relates to the field of medical facility automation, in particular to a lower limb rehabilitation training robot. The lower limb rehabilitation training robot comprises a lower limb rehabilitation training mechanism and a walking trolley mechanism. The lower limb rehabilitation training mechanism comprises a waist fixing base, hip joint motors, thigh connecting rods, thigh fixing belts, knee joint motors, crus connecting rods, crus fixing belts, ankle joint motors and sole supporting bases. The waist fixing base and the thigh connecting rods, the thigh connecting rods and the crus connecting rods, and the crus connecting rods and the sole supporting bases are connected respectively through rotating pairs, and rotate relatively by a certain angle under driving of the related motors to form coordinating gait movement. The walking trolley mechanism comprises a trolley frame, wheels, a handle and a hanging belt. The lower limb rehabilitation training mechanism is used for rehabilitation training of the aspects such as muscular strength, mobility of joint and coordination after lower limb contracture of limb hemiplegic patients, the control principle is simple, wearing and operation are easy, the application range is wide, and patients can select different modes for training according to different rehabilitation stages.

Some embodiments of the invention provide a software generated series of tests or screens to determine skeletal muscle balance as related to muscle strength and muscle flexibility. In some embodiments, a color coded muscle map illustrating the findings of the screens, is generated. The findings of the screens compile an exercise program, specifically tailored to the individual's general health and fitness state, as well as to the specific shortcomings identified in the screen. The invention also provides, in some embodiments, an exercise program adherence tracking calendar which monitors both completed exercises and exercise effectiveness as measured by changes in screen results.

Disclosed is a device for promoting decomposition of body fat and enhancing muscular strength, comprising: a base seated on a horizontal surface; a post uprightly provided in the front part of the base; a foothold mounted to be vertically movable on the base; a drive unit provided in the base to periodically and alternately raise and lower the opposite ends of the foothold; and a control section provided on the post for controlling the drive of the drive unit. The drive unit comprises a drive source mounted on the base, rotational shafts, which are respectively connected to driving axes extending from the opposite sides of the drive source, balance weights each being secured to one of the rotational shafts, which extend through the balance weights, eccentric axles each being directly formed on one of the rotational shafts, and connecting rods each being connected to one of the eccentric axles.

A system and method are presented to provide assist to a user by means of an exoskeleton with a controller capable of making the exoskeleton display active impedance. The exoskeleton assists the user by reducing the muscle effort required by the user to move his or her extremities. In one embodiment, a single-degree-of-freedom (1-DOF) exoskeleton assists a user with single-joint movement using an active impedance controller. In another embodiment, a multiple-degree-of-freedom (multi-DOF) exoskeleton assists a user with multiple-joint movement using an active impedance controller.

The invention discloses a rehabilitation evaluation method and system based on a wearable sensor. The method comprises the steps that: for a to-be-detected person, an inertia measurement unit is used for collecting knee joint posture information and calculating the knee joint movement range in the walking process; gait parameters during walking are obtained, and a gait function is estimated; supine straight leg lifting time and prone straight leg lifting time are acquired, and muscle strength information is estimated; and the rehabilitation condition of the to-be-detected person is evaluated on the basis of the knee joint movement range, the gait function and the muscle strength information. According to the rehabilitation evaluation method and system based on the wearable sensor of the invention, a patient can complete rehabilitation evaluation at home; the practicability and reliability of the method and system are high, and the economic burden of the patient is reduced.

An intra vaginal device (10) including an elongated hollow body (1 1) with side wall portions (15, 16 and 24). Secured to each wall portion (15 and 24) is a sensor (19), while secured to the wall portion (16) is a sensor (20). The sensors (19) simply measure forces directly applied by the bi-lateral contraction of the pubococcygeus, while the sensor (20) provides an indication of the puborectalis contraction forces.

Novel heterocyclic aromatic compounds are provided that are useful in stimulating endogenous production or release of growth hormone, said compounds having the general structure of formula I wherein R1, R1a, R6, Xa, Xb and Y are as described herein. The compounds provided herein are useful in treating obesity, osteoporosis (improving bone density) and in improving muscle mass and muscle strength.

The invention discloses functional compound feed special for greenhouse cultivation of litopenaeus vannamei. The feed is prepared from import fishmeal, peanut meal, fermented peanut meal, bean pulp, fermented bean pulp, yeast extract, cuttlefish meal, shrimp shell meal, high protein flour, monocalcium phosphate, granulesten, fish oil, a vitaminized mineral mixture premix compound and a functional additive. The functional additive is prepared from vitamins C, bacillus subtilis, seaweed ultrafine smashing micro powder and natural astaxanthin according to proportion. The feed effectively solves the problems of stress, immunity reduction, variety quality losses and the like caused by greenhouse large-scale intensive cultivation of the litopenaeus vannamei and meanwhile has the advantages of being balanced in nutrition, low in cost, green, environmentally-friendly and the like. Main umami substances in muscles of the litopenaeus vannamei fed through the feed are obviously improved, the total amino acid, necessary total essential amino acid and the like are improved in a certain extent, indexes such as the muscle strength, the freshness and the taste are obviously improved, the shrimp body color is close to that of wild shrimps, the immunity of juvenile shrimps and adult shrimps is obviously improved, and the survival rate is high. The feed is suitable for being used in greenhouse high-density large-scale cultivation of the litopenaeus vannamei.

The invention provides a muscle strength model optimizing method for humanoid robot synergic movement. Programming and modeling are carried out on a human skeletal muscle simulation model, and a humanoid robot is designed and developed by reference to an experiment object; the humanoid robot is controlled to do the same movement by reference to the experiment object; movement detection data of the humanoid robot and output data of the human skeletal muscle simulation model are compared, design parameters of the humanoid robot and a muscle strength prediction formula in the simulation model are modified repeatedly until the design parameters and the formula are similar, and an optimized muscular strength prediction model is obtained. The muscle strength model optimizing method for the humanoid robot synergic movement can solve the problems that muscular strength during body movement can not be directly measured through experiments in biomechanics researches of a skeletal system and a muscular system, can only be calculated by means of a muscular strength model and is uncertain, and accuracy of the simulation model is improved.

The disclosure provides novel antibodies against growth and differentiation factor-8 (GDF-8), including antibody fragments, which inhibit GDF-8 activity in vitro and in vivo. The disclosure also provides methods for diagnosing, preventing, or treating degenerative disorders of muscle, bone, or insulin metabolism.

The invention relates to a body-building training device that imitates qigong circulating vibration, which at least comprises one chassis, one driving device and one transmission unit. The driving device and transmission unit are fixed on chassis, and the structure of transmission unit is movable in the right and left direction and connected with a plurality of fore-and-aft support boards, and it is drove by one eccentric transmission shaft which is drove by motor to generate liner vibration and cooperates ith motor rotation speed to make the package base generate reciprocate with different frequencies, so the transmission unit is drove by driving device and generates liner vibration, thus the whole body is vibrated to promote blood circulation, increase muscle strength and release mental. The invention is characterized by simple structure and good economical benefit.

Provided is a health bicycle with a lower body exercise function by means of pedals and an arm exercise function as a user rotates handles. The present invention comprises a frame part F which includes a first frame F1 at a backside of which a seat F12 is engaged, and a second frame F2 which is rotatably hinged by means of a hinge shaft F3 and at an upper side of which a monitor F4 is formed; a lower body exercise means L which is engaged at a lower side of the first frame F1 and generates an exercise load so that a user steps on it and rotates it for thereby exercising a muscular strength of a lower body of the user; and an arm exercise means H which is installed at an upper side of the second frame F2 and generates an exercise load so that a user holds it and rotates it for thereby exercising arms.

A muscle strength testing and measuring apparatus contains a bar-like strength testing mechanism slidably placed over a pair of upright posts for adjustment of vertical position and allowing a variety of muscle groups to be tested by the user without any specialized knowledge. The apparatus can be used for physical training before and after exercise as well as for rehabilitation purposes. The position adjustment mechanism includes a jamming cylinder controlled by a link plate, which in turn can be activated by simple lifting or lowering the bar-like mechanism. Piezo-electric tensile sensors are placed in the middle portion of the mechanism to indicate the muscle force which signal is then transmitted to a display unit. Additional pull force strength testing units are placed over the same posts allowing also for adjustment of height position. A great number of configurations are described that can be achieved by easily switching the apparatus from one position to the next.

To provide a pressure muscle strength increasing apparatus that allows accurate adjustment of the degree of blood flow restriction when a pressure muscle strength increasing method is carried out. The pressure muscle strength increasing apparatus is comprised of a tight fitting device 100, a pressure setting segment 200, quantification segments 300, and a control segment 400. The tight fitting device 100 is wrapped around a predetermined range on a limb. The tight fitting device 100 has an air-tight gas bag. The compression force applied to the limb can be varied by supplying the air to and removing the air from the gas bag. The pressure setting segment 200 controls the supply and removal of the air into and from the gas bag. The quantification segment 300 is intended to be rest on the limb which the tight fitting device 100 is wrapped around on the distal side thereof to quantify a quantification target that varies depending on the increase and decrease of the compression force. The control segment 400 controls the pressure setting segment 200 based on the quantification target. As described above, the pressure muscle strength increasing apparatus automatically controls the compression force based on the quantification target.