88results about How to "Reduce fat accumulation" patented technology

Disclosed herein are compositions and methods used to modulate a NH2-terminal Jun Kinase activity. These compositions and methods can be employed to regulate metabolic disorders associated with, for example, insulin such as diabetes. The reduction in NH2-terminal Jun Kinase activity can lead to the reduction in weight and improve insulin sensitivity.

This invention discloses methods of using krill oil and compositions comprising krill oil to treat risk factors for metabolic, cardiovascular, and inflammatory disorders. The present invention also relates to methods of using compositions comprising krill oil to modulate biological processes selected from the group consisting of glucose metabolism, lipid biosynthesis, fatty acid metabolism, cholesterol biosynthesis, and the mitochondrial respiratory chain. The present invention further includes pharmaceutical and / or nutraceutical formulations made from krill oil, methods of making such formulations, and methods of administering them to treat risk factors for metabolic, cardiovascular, and inflammatory disorders.

The present invention relates to the Bifidobacterium CECT 7765 strain, to its cell components, metabolites, and secreted molecules, to the combinations thereof with other microorganisms, and to compositions comprising the aforementioned products, as well as to the use of a strain of the Bifidobacterium pseudocatenulatum species, or to using the CECT 7765 strain for the prevention and / or treatment of obesity, overweight, hyperglycemia and diabetes, preferably type 2 diabetes mellitus, hepatic steatosis or fatty liver, dyslipidemia, metabolic syndrome, immune system dysfunction associated with obesity and overweight; and an unbalanced composition of the intestinal microbiota associated with obesity and overweight.

The invention discloses a healthcare feed used for grass carps to overwinter and a preparation method for the healthcare feed. The healthcare feed comprises the following components in percentage by weight: 0.0003 to 0.0075 percent of ferrous sulfate, 0.00003 to 0.00025 percent of anhydrous cupric sulfate, 0.0002 to 0.002 percent of zinc sulfate, 0.0002 to 0.0004 percent of vitamin A, 0.0001 to 0.0004 percent of vitamin D3, 0.5 to 2 percent of calcium dihydrogen phosphate, 5 to 25 percent of soya bean meal, 3 to 8 percent of alfalfa meal, 3 to 10 percent of fish meal, 0.05 to 0.08 percent of bile acid, 1 to 3 percent of seaweed powder and 100 percent of flour. The healthcare feed provided by the invention meets requirements of fish bodies for nutrition by selecting imported fish meal and soya bean meal, improves the intestinal environment of fish by adding high-quality dietary fibers such as the alfalfa meal and the like, and reduces liver fat accumulation of the grass carps by addingadditives such as the bile acid and the like, so that fish is more healthy; therefore, the stress bleeding when the grass carps are sold can be reduced and the grass carps can overwinter safely.

This invention relates to the enhancement of feed efficiency and growth rate, and the reduction of fit accumulation to produce better quality meat by administration of an exogenous gene sequence comprising the complementary DNA sequence of growth hormone releasing factor to stimulate the production of the endogenous hormone peptide growth hormone. This invention further relates to methods for producing such gene sequence.

The invention provides a micro-ecological preparation containing a ginseng extract and probiotics. The ginseng extract is a water extract of ginseng, and the probiotics are selected from one, two or acombination of bifidobacterium, lactobacillus, streptococcus, bacillus, clostridium butyricum and yeast. By means of components of the traditional Chinese medicine ginseng, a substrate which is needed for growth and synthesis of active effective molecules can be provided for the probiotics, conversely, by means of a complex enzyme system in the probiotics, use of the components of the traditionalChinese medicine ginseng is further improved, by using the ginseng and the probiotics in combination, combined effects can be achieved, and compared with individual use of a traditional Chinese medicine preparation or the probiotics, combined use of the ginseng and the probiotics has the advantages that an effect of regulating intestinal flora is enhanced, and not only can intestinal flora compositions be improved and blood glucose and lipid metabolism of the body be regulated, but also fat accumulation of the body can be further reduced.

The long-term usage of AICR (5-aminio, 4-imidazole carboxamide riboside) to produce sustained metabolic and biological changes in mammals that overcome insulin resistance, i.e., increase insulin sensitivity, and result in benefits in diseases and conditions such as diabetes, hypertension, atherosclerosis, polycystic ovary syndrome and gallstones is described long-term usage of AICAR, particularly intermittent administration, e.g., three days per week, appears to have some of the positive effects of exercise, having an impact on the amount Of food consumed by a subject and resulting in reduced fat build-up and increase in muscle mass. Therefore, AICAR administration has a positive impact in reducing obesity. AICAR can also Prove useful in preventing or treating vascular diseases associated with hyperglycemia, high plasma levels of free fatty acids (FFA) and triglyceride, and insulin resistance by virtue of the fact that this agent activates fatty acid oxidation. Animal tests have Shown that chronic intermittent treatment with AICAR has not resulted in any noticeable toxic effects. AICAR and related compounds are activators of AMP-activated protein kinase (AMPK) and, furthermore, are effective at decreasing malonyl CoA levels in the animal.

Edible compositions useful for weight management in male animals are disclosed. The compositions comprise one or more isoflavones or isoflavone metabolites and are particularly useful for reducing or preventing the accumulation of body fat. Also disclosed are methods useful for weight management in an animal utilizing compositions comprising one or more isoflavones. The compositions and methods are particularly useful for the reduction or prevention of body fat accumulation during periods of excess caloric intake, and preferably have a sparing effect on lean body mass.

This invention relates to the enhancement of feed efficiency and growth rate, and the reduction of fat accumulation to produce better quality meat by administration of an exogenous gene sequence comprising the complementary DNA sequence of growth hormone releasing factor to stimulate the production of the endogenous hormone peptide growth hormone. This invention further relates to methods for producing such gene sequence.

The invention discloses a 4 percent special compound premix for yellow-head catfish. The 4 percent special compound premix is prepared from the following raw materials in parts by weight: 3-6 parts of compound trace elements, 1.5-2.5 parts of compound vitamins, 30-40 parts of mineral substances, 4-5 parts of vitamin C, 0.5-1 part of vitamin E, 5-8 parts of 2 percent xanthophylls, 0.5-1 part of cholates substances, 2-3 parts of taurine, 15-20 parts of 50 percent choline chloride, 2-3 parts of a fish phagostimulant, 0.5-1 part of an aquatic disease-prevention growth promoting agent and 5-6 parts of edible salt. The 4 percent special compound premix is balanced in various nutritional components, reasonable in proportion and suitable for rapid growth of the yellow-head catfish, and can enable the body colors of the yellow-head catfish to be close to those of wild products.

The invention discloses a bacterial strain as well as a composition and application, and relates to the technical field of strain separation and application. The Cristinia sp. provided by the invention can be applied to treatment or prevention of liver function impairment and liver function impairment related diseases, alimentary canal mucosal injury and alimentary canal mucosal injury related diseases, diabetes, obesity and obesity related diseases. The inventor verifies that the Cristinia sp. provided by the invention has no toxic or side effect on the kidney and can reduce the weight of the liver; the initial steatohepatitis focus can be treated; fat accumulation of liver cells can be slowed down; AST and ALT in serum can be reduced; and abdominal white fat inflammatory lesion can be reduced. The Cristinia sp. can also repair the digestive tract mucosa, recover the barrier function of the mucosa, and prevent and treat intestinal leakage, peptic ulcer and other diseases caused by barrier function impairment. The Cristinia sp. also has the effects of reducing fasting blood-glucose of a body, regulating insulin level and reducing body fat of mammals, and has the effects of preventing and treating diabetes and improving the metabolic function of obese patients.

The invention relates to the field of foods, and discloses a composition based on lactobacillus plantarum and a preparation method of the composition. The composition comprises lactobacillus plantarumfreeze-dried powder, white kidney bean extract, inulin, erythritol and vitamin C. The composition is capable of reducing body weight, reducing fat accumulation in the body, reducing the organ ratio and the body fat ratio, reducing the leptin level and reducing blood fat, and can be used for preventing and treatment obesity. The lactobacillus plantarum 1701 used for preparing the lactobacillus plantarum freeze-dried powder has good tolerance and adhesiveness, can significantly reduce body weight, reduce fat accumulation in the body, reduce the organ ratio and the body fat ratio and reduce theleptin level and blood fat, and can be used for preventing and treatment obesity; and in addition, after being inactivated, the lactobacillus plantarum 1701 also has the function of losing weight, sothat the stability and the shelf life of a product are longer.

The present invention describes a method to reduce body weight, fat accumulation and adipocyte size by administering the probiotic bacterium Parabacteroides goldsteinii. This probiotic bacterium can therefore be used to treat obesity in animals and humans.

It is an object of the invention to provide a novel therapeutic agent that can reduce visceral fat accumulation to prevent or treat metabolic syndrome. In order to achieve this object, the invention provides a therapeutic agent for metabolic syndrome that comprises, as an active ingredient, dietary fiber aggregation in which water-soluble β-glucan has the highest content. Particularly effective as the water-soluble β-glucan is water-soluble β-glucan having a β-1,3 glycoside bond and β-1,4 glycoside bond in the same molecule.

A method of treating and preventing type 2 diabetes and obesity an animal, including mammals and humans, in which a therapeutically effective amount of catalpic acid to the animal is administered orally or parentally.

The present disclosure concerns a cream-based composition and method which reduces fat deposits upon topical application to the skin. The active ingredients of the composition include the active ingredients deoxycholic acid and phosphatidyl choline which are mixed together with a cream composition. The active ingredients may be combined with any suitable pharmaceutical vehicle to provide the fat-reducing composition claimed herein. The composition is topically applied to a skin area over a period of days or months in order to reduce fat deposits that have collected beneath the dermis.

Disclosed is a method for preparing a CLA-enriched structured lipid by a transesterification of medium chain triglyceride (MCT) with ester or free fatty acid form of CLA using lipases, and use of the same. It has been known that CLA mainly exists in an acid form, and has various beneficial biological activities, but rapid oxidation property during storage. And also, animal fat or plant oil, widely ingested by animals or humans, is naturally produced as an acylglycerol form containing various fatty acids. The CLA-containing structured lipid is manufactured by mixing free or ester form of CLA with acylglyceride at a molar ratio of 1:1~1:5, adding immobilized lipase of 2.2~20% by weight of CLA and acylglyceride to the mixture with a solvent, and incubating at 35~75° C. for 1-36 hours. The CLA-containing structured lipid is a natural TG form and contains a high content of CLA, characterized by at least 15% content of CLA in total fatty acid composition, and at least 5% of CLA at sn-2 position. Accordingly, with the CLA-enriched MCT being administrated, it can efficiently provide biological activities of CLA, such as inhibition of carcinogenesis and reduction of fat accumulation in a body, as well as rapidly supply calories, an innate nutritional property of MCT.

The invention belongs to the field of medicine preparation and particularly relates to an application of berberine in a medicine for treating non-alcoholic fatty liver disease. According to the invention, db / db mouse with diabetic obesity and NAFLD (Non-Alcoholic Fatty Liver Disease) is employed to simulate a fat NAFLD patient, and a mouse with non-obese fatty liver caused by methionine-choline deficient (MCD) is used as a model to simulate a non-fat NAFLD patient so as to observe the effect of BBR. Shown by all test results, the BBR not only can reduce the weight of the obese mouse and improve the glycometabolism and lipid metabolism, but also can treat the concurrent fatty liver of the obese mouse, and also has obvious treatment effect on the fatty liver of the non-obese mouse, and the results are verified in a cell model simulated in vitro, so that the BBR has obvious treatment effect on the obesity and the non-obese NAFLD surely and can be used in preparation of the medicine for treating the NAFLD.

The invention relates to the use of triglycerides which an enhanced portion of the palmitic acid residues in the sn-2 position for an early in life diet for improving the development of a healthy body composition, in particular prevention of obesity, later in life.

The invention provides an efficient health-care product for supplementing selenium and a preparation method thereof. The product comprises 60-120 parts by weight of VE, 40-50 parts by weight of organic selenium, and 1800-2100 parts by weight of honey. The preparation method of the health-care product comprises weighing the VE, the organic selenium and the honey, conducting uniform mixing, and conducting refrigeration in a refrigerator until the mixture becomes a paste and no delamination exists. The health-care product for supplementing selenium is a compound containing three ingredients, and while supplementing selenium, the health-care product contains the VE so as to promote selenium absorption of organisms, reduce selenium loss in bodies, and raise the utilization rate of selenium. Meanwhile, selenium can also promote VE absorption, reduce VE loss in bodies, and raise the utilization rate of the VE as well. Besides, with the addition of honey, the health-care product becomes the selenium-VE-honey mixture; and not only the honey improves a mouth feel, but more importantly, an antioxidant component pinocembrin peculiar to the honey realizes efficacy synergy with the selenium. Meanwhile, the honey contains a plurality of vitamins and biological enzymes for efficacy complementation with the selenium. The three raw materials of the selenium, the VE and the honey stimulate one another and play the health-care effect of "1+1+1>3".

The invention discloses an active granular formula feed for feeding carp and a preparation method of the active granular formula feed. Every 100 parts of the active granular formula feed comprise the following components in part(s) by weight: 0.01-0.03 part of ferrous sulfate, 0.0012-0.01 part of anhydrous cupric sulfate, 0.0058-0.058 part of zinc sulfate, 0.0002-0.0004 part of vitamin A, 0.0001-0.0006 part of vitamin D, 0.1-0.3 part of L-ascorbic acid-2-phosphate, 0.2-0.4 part of hydroxy methionine, 0.02-0.1 part of bile acid, 0.1-0.3 part of montmorillonite, 0.01-0.04 part of bacillus subtilis, 0.05-0.1 part of an enzymic preparation, 0.03-0.05 part of taurine, 0.5-2.5 parts of monocalcium phosphate, 20-40 parts of bean pulp, 3-8 parts of alfalfa meal, 10-20 parts of imported fish meal, 1-2 parts of soyabean lecithin oil, 1-3 parts of other greases and the balance of wheat middling. As multiple vitamins and mineral substances are added to the active granular formula feed disclosed by the invention, the metabolism of the fishes is prompted, the survival rate at the early stage is increased, the growing speed at the late stage is increased, the fishes are kept healthy and grow rapidly, the feed coefficient is reduced, and great benefits are created for breeders.

The invention discloses a puffed compound feed for raising grass carps and a preparation method thereof. Each 100 parts of compound feeds contain the following components in parts by weight: 0.01-0.3 part of ferrous sulfate, 0.0012-0.01 part of anhydrous cupric sulfate, 0.0058-0.058 part of zinc sulfate, 0.0002-0.0004 part of vitamin A, 0.0001-0.0006 part of vitamin D3, 0.0857-0.15 part of L-ascorbic acid-2-phosphate, 0.02-0.08 part of bile acid, 0.1-0.25 part of montmorillonite, 0.5-2.5 parts of monocalcium phosphate, 15-30 parts of soya bean meal, 3-8 parts of alfalfa meal, 3-10 parts of fish meal and the balance being flour. The puffed compound feed for grass carps selects the fish meal and the soya bean meal to meet the nutrition needed by a fish body; high-quality dietary fibers including the alfalfa meal and the like are added to improve the intestinal tract environment of fish; various vitamins and mineral substances are added to promote the metabolism of the fish body; the bile acid is added so that the fat accumulation in the liver of the grass carps is prevented; the montmorillonite is added so that the intestinal tract environment is improved, the nutrition absorption is promoted, and furthermore, the fish body is healthy and can grow rapidly to reach the set target.

The present invention discloses a seasoned orange peel tea containing soluble dietary fibers, wherein seasoned orange peel and tea leaves are subjected to raw material extraction, and are matched with soluble dietary fibers, white sugar, citric acid and water to prepare the seasoned orange peel tea. The seasoned orange peel tea has functions of digestion aiding, gastric qi removing, and abdominal fat accumulation reducing. According to seasoned orange peel tea of the present invention, the warm-natured seasoned orange peel can be matched with obtuseleaf senna seed, lotus leaf and other herbs having medium and slightly cold natures so as to provide a good effect; and the seasoned orange peel tea contains the soluble dietary fibers so as to provide effects of intestine smoothing and constipation relieving.

The invention relates to technical field of functional food and medical health care, and discloses application of a broadleaf holly leaf aqueous extract and a drug composition for regulating intestinal microecology. The invention provides application of the broadleaf holly leaf aqueous extract to preparation of a drug for regulating the intestinal microecology, and the drug composition for regulating the intestinal microecology. Through animal experiments, the application of the broadleaf holly leaf aqueous extract to regulating of the intestinal microecology is studied, it is found that by improving diversity of mice intestinal flora, the broadleaf holly leaf aqueous extract effectively regulates intestinal flora disturbance and improves the barrier function of the intestinal tract, lowers expression of inflammatory factors of intestinal tissue, promotes secretion of intestinal mucins, and thus achieves the effects of lowering lipid and losing weight, lowering blood glucose and lowering fat accumulation; and it shows that the broadleaf holly leaf aqueous extract can regulate diseases of obesity, type 2 diabetes, non-alcoholic fatty liver disease and the like caused by intestinal flora disturbance.

The invention relates to the field of food, and discloses a probiotic tablet capable of controlling weight and a preparation method of the probiotic tablet. The probiotic tablet is prepared from lactobacillus fermentum freeze-dried powder, lactobacillus plantarum freeze-dried powder, a white kidney bean extract, a green coffee bean extract, blueberry powder, fresh ginger powder, inulin, erythritol, a direct pressure type auxiliary material, vitamin C and magnesium stearate, wherein the lactobacillus fermentum is named as WHH3906, and the lactobacillus plantarum is named as 1701. In the probiotic tablet disclosed by the invention, the lactobacillus plantarum 1701 and the lactobacillus fermentum WHH3906 have a synergistic effect, so that a relatively good lipid-lowering and weight-losing effect can be achieved after compounding; the blueberry powder and the fresh ginger powder can relieve chronic inflammation and reduce pathogenic bacteria in intestinal tracts, and growth and field planting of the lactobacillus plantarum and the lactobacillus fermentum are facilitated; and inulin and erythritol can be used as energy substances of the lactobacillus plantarum and the lactobacillus fermentum to promote the growth of the the lactobacillus plantarum and the lactobacillus fermentum, so that the lactobacillus can play a role in controlling the weight.

The invention discloses an application of bletilla striata oligosaccharide and a composition thereof in adjusting glucose and lipid metabolism disorder. The degree of polymerization of bletilla striata oligosaccharide is 2-20 and the molecular weight range is 200-5000 Da. The bletilla striata oligosaccharide and the composition thereof play roles of inhibiting fat generation, reducing glucose concentration of blood and the like, can adjust glucose and lipid metabolism disorder, and plays a relatively good role of improving glucose intolerance caused by high calorie diets and diabetes caused byobesity and the like. The bletilla striata oligosaccharide and the composition thereof can be used for prevention and treatment of disease of glucose and lipid metabolism disorder and intestinal flora disturbance thereof.