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Micro-ecological preparation containing ginseng extract and probiotics and production method and application of micro-ecological preparation containing ginseng extract and probiotics

A micro-ecological preparation, ginseng extraction technology, applied in the directions of medical preparations containing active ingredients, medical preparations with non-active ingredients, plant/algae/fungus/moss ingredients, etc., can solve the problems of limited application of Bacillus subtilis, etc., To achieve the effect of improving the composition of intestinal flora, enhancing regulation, and regulating blood sugar and blood lipid metabolism

Pending Publication Date: 2020-11-20
TIANJIN MODERN INNOVATIVE TCM TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the use of Bacillus subtilis in obesity or metabolic diseases is still very limited

Method used

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  • Micro-ecological preparation containing ginseng extract and probiotics and production method and application of micro-ecological preparation containing ginseng extract and probiotics
  • Micro-ecological preparation containing ginseng extract and probiotics and production method and application of micro-ecological preparation containing ginseng extract and probiotics
  • Micro-ecological preparation containing ginseng extract and probiotics and production method and application of micro-ecological preparation containing ginseng extract and probiotics

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] Embodiment 1. Preparation of Ginseng Extract

[0035] The ginseng powder was decocted with 6 times of water for 60 minutes by the water extraction method, and the medicinal soup was obtained by filtering, and concentrated by a rotary evaporator into a ginseng extract with a measured density of 1.02 g / L at 20°C. In the obtained ginseng extract, the total content of ginsenoside Rg1 and Re was 0.75%, and the content of ginsenoside Rb1 was 0.31%.

Embodiment 2

[0036] Embodiment 2. The preparation of the probiotics of Bacillus subtilis and ginseng extract

[0037] The activated Bacillus subtilis was inoculated and cultivated until the OD600 of the bacterial liquid was 1, the cultivation was stopped, and then the thalline was collected by centrifugation at 4°C, and the thalline was washed with pure water for 3 times to obtain the bacterium sludge (inverted and stagnant mud) and weighing.

[0038] Gelatin, trehalose, mannitol and vitamin C are formulated into an aqueous solution of gelatin 0.1g / ml, trehalose 0.2g / ml, mannitol 0.1g / ml and vitamin C 0.01g / ml, which is used as a protective agent solution.

[0039] The bacteria slime, protective agent solution and the ginseng extract of Example 1 were mixed according to the weight ratio of 1:0.5:0.5, and then freeze-dried after mixing evenly (wherein, the freezing temperature was -50° C.), and finally obtained powdered ginseng extract. Ecological preparations. The number of live bacteria...

Embodiment 3

[0040] Example 3. Preparation of microecological preparations of Saccharomyces cerevisiae and ginseng extract

[0041] According to the method of Example 2, Saccharomyces cerevisiae was used to replace Bacillus subtilis to prepare a probiotics containing Saccharomyces cerevisiae and ginseng extract. Wherein the weight ratio of the ginseng extract to the Saccharomyces cerevisiae fungus sludge is 0.6:1.

[0042] Effect example

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Abstract

The invention provides a micro-ecological preparation containing a ginseng extract and probiotics. The ginseng extract is a water extract of ginseng, and the probiotics are selected from one, two or acombination of bifidobacterium, lactobacillus, streptococcus, bacillus, clostridium butyricum and yeast. By means of components of the traditional Chinese medicine ginseng, a substrate which is needed for growth and synthesis of active effective molecules can be provided for the probiotics, conversely, by means of a complex enzyme system in the probiotics, use of the components of the traditionalChinese medicine ginseng is further improved, by using the ginseng and the probiotics in combination, combined effects can be achieved, and compared with individual use of a traditional Chinese medicine preparation or the probiotics, combined use of the ginseng and the probiotics has the advantages that an effect of regulating intestinal flora is enhanced, and not only can intestinal flora compositions be improved and blood glucose and lipid metabolism of the body be regulated, but also fat accumulation of the body can be further reduced.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine biotechnology, and specifically relates to a microecological preparation containing ginseng extract and probiotics, a preparation method and application thereof. Background technique [0002] The incidence of obesity is rising worldwide and has become a global disease that threatens human health and reduces the quality of human life. As a complex disease that interacts with genetic factors, environmental factors, and lifestyle, obesity increases the risk of metabolic diseases, such as hyperlipidemia, type 2 diabetes, and fatty liver. The root cause of obesity is the imbalance of energy intake and consumption, but the etiology of obesity has not been fully clarified. It is currently believed that obesity is mainly a chronic disease formed under the combined action of host factors and environmental factors. It is often difficult to fight obesity or metabolic diseases through reasonable d...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/258A61K47/42A61K47/36A61K47/26A61K47/22A61P3/04A61P3/10A61P3/06A61P1/16A23L33/105A23L33/135A23L33/14A23L33/15A61K35/745A61K35/747A61K35/744A61K35/742A61K36/064
CPCA61K36/258A61K35/745A61K35/747A61K35/744A61K35/742A61K36/064A61K47/42A61K47/36A61K47/26A61K47/22A61P3/04A61P3/10A61P3/06A61P1/16A23L33/105A23L33/135A23L33/14A23L33/15A23V2002/00
Inventor 王苹黄鹤白亮
Owner TIANJIN MODERN INNOVATIVE TCM TECH CO LTD
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