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Hybrid polypeptides with selectable properties

ActiveUS20060293232A1Reverse glucose intoleranceIncrease massNervous disorderPeptide/protein ingredientsBlood lipidsGestational diabetes
The present invention relates generally to novel, selectable hybrid polypeptides useful as agents for the treatment and prevention of metabolic diseases and disorders which can be alleviated by control plasma glucose levels, insulin levels, and / or insulin secretion, such as diabetes and diabetes-related conditions. Such conditions and disorders include, but are not limited to, hypertension, dyslipidemia, cardiovascular disease, eating disorders, insulin-resistance, obesity, and diabetes mellitus of any kind, including type 1, type 2, and gestational diabetes.
Owner:ASTRAZENECA PHARMA LP

Hierarchal data management

A hierarchal data management system for a storage device includes an entity relationship discover to generate meta data from a business object, a file manager to create a partition based on the metadata, a data mover to generate a logical partitioning key and to store the logical partitioning key in the metadata for the partition. The file manager includes a data management policy to define a data class and a storage policy to map the data class to the storage device to form a partition table.
Owner:DAHBOUR ZIYAD M

Use of lignocellulosics solvated in ionic liquids for production of biofuels

The present invention provides a method for converting lignocellulosic material into biofuel. In particular embodiments, the method comprises pre-treating lignocellulosic material by dissolving the material in ionic liquids. The pretreated lignocellulosic material can be isolated, such as by precipitation with a regenerating solvent (e.g., water), and be used directly in the formation of biofuel, including undergoing hydrolysis to form sugar and fermentation to form fuel, such as bioethanol. The ionic liquid can be recycled for further use, such as by evaporation of the water introduced during precipitation, and the recycling provides a route to a hemicellulose rich fraction and an ionic liquid of consistent quality and wood dissolution characteristics. The recovered hemicelluloses are of significant utilization potential toward commodity and specialty applications.
Owner:NORTH CAROLINA STATE UNIV

System and Methods for RAID Writing and Asynchronous Parity Computation

A computer storage management system for managing a first plurality of data storage units, the system including: (a) an asynchronous parity computation manager which, responsive to a write operation in which an incoming data portion is to be written into an individual storage unit from among the storage units, deposits the incoming value in the individual storage unit an stores a copy of the data element in a pre-parity storage area, and wherein asynchronously with depositing the incoming value in the individual storage unit, the asynchronous parity computation manager is operative to compute parity data corresponding to the incoming data portion and to other data portions which are associated with the incoming data portion and to store the parity data; and (b) a post-loss data recovery manager operative to recover lost data including determining whether at least one parity value associated with at least one data portion within said lost data is not current and, for at least one non-current parity, using information stored in the pre-parity storage area to generate, after said lost data has been lost, a current parity to replace said non-current parity and using said current parity to recover said lost data.
Owner:KAMINARIO TECH

System and methods for RAID writing and asynchronous parity computation

A computer storage management system for managing a first plurality of data storage units, the system including: (a) an asynchronous parity computation manager which, responsive to a write operation in which an incoming data portion is to be written into an individual storage unit from among the storage units, deposits the incoming value in the individual storage unit and stores a copy of the data element in a pre-parity storage area, and wherein asynchronously with depositing the incoming value in the individual storage unit, the asynchronous parity computation manager is operative to compute parity data corresponding to the incoming data portion and to other data portions which are associated with the incoming data portion and to store the parity data; and (b) a post-loss data recovery manager operative to recover lost data including determining whether at least one parity value associated with at least one data portion within said lost data is not current and, for at least one non-current parity, using information stored in the pre-parity storage area to generate, after said lost data has been lost, a current parity to replace said non-current parity and using said current parity to recover said lost data.
Owner:KAMINARIO TECH

Resource-amount calculation system, and method and program thereof

A response-time-difference calculation / request-number converting means (523) calculates a change of throughput based on a response time monitoring result, a target value of the response time, a quantitative model and performance specification information. A server selection means (524) input the performance specification information in the quantitative model acquired to calculate a throughput of each of pool servers, selects a pool server having a throughput corresponding to a throughput larger than and closest to the change of throughput, and instructs provisioning means (513) to execute configuration modification control on the selected pool server (502). The provisioning means (513) modifies the configuration so that the pool server (502) functions as an application server.
Owner:NEC CORP

Iontophoretic drug delivery device and reservoir and method of making same

A reservoir electrode assembly of the present invention for an iontophoretic drug delivery device includes an electrode and a hydrophilic reservoir situated in electrically conductive relation to the electrode. The hydrophilic reservoir is formed from a bibulous hydrophilic cross-linked polymeric material having a first surface and a second surface that is adhesively adherent to the electrode. The first surface of the polymeric material is releasably adhesively adherent when applied to an area of a patient's skin. The polymeric material has a cohesive strength forms an adhesive bond with a bond strength between the second surface of the polymeric material to the electrode that is greater than the cohesive strength of the polymeric material. Additionally, an adhesive bond strength of the first surface of the polymeric material to the applied area of the patient is less than the cohesive strength of the polymeric material so that upon removal of the reservoir assembly of the invention from the applied area of the patient, substantially no polymeric material remains on the applied area and the hydrophilic reservoir remains substantially intact and adhesively adherent to the electrode.
Owner:LINCOLN FAIR LAWN ASSOC

Compositions for delivering peptide yy and pyy ag0nists

The present invention provides a composition (e.g., a pharmaceutical composition) comprising at least one delivery agent compound and at least one of peptide YY (PYY) and a PYY agonist. Preferably, the composition includes a therapeutically effective amount of peptide YY or the PYY agonist and the delivery agent compound. The composition of the present invention facilitates the delivery of PYY, a PYY agonist, or a mixture thereof and increases its bioavailability compared to administration without the delivery agent compound. PPY and PYY agonists possess activity as agents to reduce nutrient availability, including reduction of food intake.
Owner:NOVO NORDISK AS

Malicious code detection method and system based on plurality of URLs (Uniform Resource Locator)

The invention discloses a malicious code detection method based on a plurality of URLs (Uniform Resource Locator), comprising the following steps of: capturing all network communication data packets within appointed time intervals; sequentially analyzing all the network communication data packets and extracting the URL in each data packet; carrying out formalization treatment on all the extracted URLs; matching the URLs (which are subjected to the formalization treatment) as URLs to be detected with a characteristic database; and if the matching is successful, carrying out matching with a data model base, determining threat types and outputting corresponding detection results. The invention further discloses a malicious code detection device based on the plurality of URLs. According to the malicious code detection method and system disclosed by the invention, the disadvantages and the limitation of current anti-virus software characteristic code matching and URL filtering are solved; and the detectable rate of a malicious Trojan program is greatly improved.
Owner:BEIJING ANTIY NETWORK SAFETY TECH CO LTD

Resource optimization using environmental and condition-based monitoring

In a method for dynamically optimizing resource utilization in a system over time according to one or more objectives, data including information indicative of current environmental conditions, upcoming environmental conditions, a current state of a system configuration, and current system operating conditions is dynamically updated. Automatic analysis of the data using a probabilistic model based on conditional relationships is performed periodically. For each periodically generated set of possible system control actions, a probabilistic model is used to automatically analyze each possible system control action and an optimal system control action is selected based on a set of current utility functions. For each periodically generated set of possible system control actions, control of the system according to the optimal system control action selected from the possible system control actions. Resource optimization couples condition-based and environmental monitoring with automated reasoning and decision making technologies, to develop real time optimal control and decision strategies.
Owner:MICHIGAN AEROSPACE

Nuclear Assisted Hydrocarbon Production Method

A method is disclosed for the temporary or permanent storage of nuclear waste materials comprising the placing of waste materials into one or more repositories or boreholes constructed into an unconventional oil formation. The thermal flux of the waste materials fracture the formation, alters the chemical and / or physical properties of hydrocarbon material within the subterranean formation to allow removal of the altered material. A mixture of hydrocarbons, hydrogen, and / or other formation fluids are produced from the formation. The radioactivity of high-level radioactive waste affords proliferation resistance to plutonium placed in the periphery of the repository or the deepest portion of a borehole.
Owner:BAIRD JAMES RUSSELL

Hybrid Polypeptides with Selectable Properties

InactiveUS20090286723A1Reverse glucose intoleranceIncrease massSenses disorderPeptide/protein ingredientsBlood lipidsEating disorders
The present invention relates generally to novel, selectable hybrid polypeptides useful as agents for the treatment and prevention of metabolic diseases and disorders which can be alleviated by control plasma glucose levels, insulin levels, and / or insulin secretion, such as diabetes and diabetes-related conditions. Such conditions and disorders include, but are not limited to, hypertension, dyslipidemia, cardiovascular disease, eating disorders, insulin-resistance, obesity, and diabetes mellitus of any kind, including type 1, type 2, and gestational diabetes.
Owner:ASTRAZENECA PHARMA LP

Pre-vaporization formulation for controlling acidity in an e-vaping device

ActiveUS20170086500A1Increase in harshnessTaste be degradeTobacco treatmentPharmaceutical delivery mechanismChemistryOctanoic Acids
A pre-vaporization formulation for an e-vaping device includes a vapor former, optionally water, nicotine, nicotine bitartrate and an acid. The pH of the pre-vaporization formulation is between about 4 and about 6. The acid can include one or more of pyruvic acid, formic acid, oxalic acid, glycolic acid, acetic acid, isovaleric acid, valeric acid, propionic acid, octanoic acid, lactic acid, sorbic acid, malic acid, tartaric acid, succinic acid, citric acid, benzoic acid, oleic acid, aconitic acid, butyric acid, cinnamic acid, decanoic acid, 3,7-diemthyl-6-octenoic acid, 1-glutamic acid, heptanoic acid, hexanoic acid, 3-hexenoic acid, trans-2-hexenoic acid, isobutyric acid, lauric acid, 2-methylbutyric acid, 2-methylvaleric acid, myristic acid, nonanoic acid, palmitic acid, 4-pentenoic acid, phenylacetic acid, 3-phenylpropionic acid, hydrochloric acid, phosphoric acid and sulfuric acid.
Owner:AKRIA CLIENT SERVICES LLC

System and method for monitoring communication networks using data stream characterization

A system and method for automatically monitoring communications networks and for determining network configuration use data stream characterizations. The system comprises a plurality of measurement probes that passively probe the network and collect data packets carried by data streams in the network. The system further comprises characterization computational units that process the collected data packets and produce data stream characterizations from the collected data packets. The data stream characterizations represent individual data streams in an arbitrarily unique manner. The system still further comprises a configuration processing unit that compares data stream characterizations taken at different points in the network and determines data stream paths through the network based on data stream characterization matching. The method for automatically monitoring communications networks comprises the steps of passively probing the data streams to produce sets of collected data packets from the data streams, determining data stream characterizations from the collected data packets, and comparing the data stream characterizations to one another to identify matching characterizations.
Owner:AGILENT TECH INC

Preservation of exposed cut fresh fruit

PCT No. PCT / AU96 / 00824 Sec. 371 Date Jun. 22, 1998 Sec. 102(e) Date Jun. 22, 1998 PCT Filed Dec. 20, 1996 PCT Pub. No. WO97 / 23138 PCT Pub. Date Jul. 3, 1997A package of exposed fresh fruit including cut pieces of fruit, a packaging material and an edible gel. The packaging material encloses the fruit and allows transmission of oxygen and carbon dioxide to maintain an atmosphere about the fruit of at least 2% oxygen. The edible gel coats exposed surfaces of the fruit. The gel coating includes an anti-oxidant to retard browning and sufficient acidic constituents to establish and maintain on the exposed surfaces of the fruit a pH below 3.
Owner:AUSTRALIAN FOOD IND SCI CENT

Network model audit and reconciliation using state analysis

A method for auditing and reconciliation of a network with a network model that includes identifying an audit state for each network resource included in the network model, storing the audit state for each resource, coupling the stored audit state information with information regarding the resource, reporting a calculated value reflecting the aggregate audit states of the resources, monitoring the calculated value, and triggering a reconciliation process when the calculated value drops below a defined threshold. The calculated value can be a best-case aggregate accuracy percentage, worst-case aggregate accuracy percentage, or presumed average aggregate accuracy percentage. The audit state can be stored as an additional field in the primary data store for the network model or in a separate data store that is associated with the primary data store. The audit state can be unconfirmed, confirmed, or suspect. The audit state is used to trigger and / or measure audit and reconciliation processes.
Owner:SPRINT CORPORATION

Methods for implementing a dynamic frequency selection (DFS) feature for WLAN devices

Various regulatory domains promulgate standards to define how wireless devices should operate in certain frequency bands. The 5 GHz spectrum is of particular importance to certain regulatory domains because of radar systems also operating in this spectrum. To avoid interference with such radar systems, wireless devices operating in this spectrum should be able to detect radar and quickly vacate any channels currently used by the radar systems. Techniques are provided for performing startup scans for radar, identifying backup channels for a possible channel switch, and efficiently changing channels in the event of radar detection in the operating channel. These techniques advantageously meet current regulatory standards governing DFS while minimizing network startup delays and disruption to users during a radar event.
Owner:QUALCOMM INC

Method and system of promptly processing real-time media stream data packet

A method and system for fast transporting real-time media stream data package is based on the Real-time Transport Protocol / Real-time Transport Control Protocol of User Datagram Protocol for network nodes such as media gateway, Integrated Access Device (IAD) and multimedia terminal. The improvement of the system lies in the adding of an IP data package fast filter module, a UDP fast sending module and a policy ARP table process module based on local UDP port. The method involves: fast receiving the real-time media stream data package transmitted on the basis of RTP / RTCP protocol; fast sending the real-time media stream data package transmitted on the basis of RTP / RTCP protocol; and a policy ARP table based on UDP port and its refurbishing system.
Owner:ZTE CORP

Method & apparatus for an auxiliary train control system

A method and an apparatus for a train control installation are disclosed, and are based on the absolute permissive block concept. The train control installation employs a plurality of generic absolute block signal units (ABSU), wherein each signal unit includes means for detecting the crossing of a train passed a discrete point, means for exchanging data with adjacent ABSUs, means for generating and communicating a movement authority limit to a train, means for generating and displaying a signal indication, and means for enforcing a stop aspect. The train control installation can be used in conjunction with a communication based train control (CBTC) system to provide a degraded mode of operation without impacting the availability and the reliability of the CBTC system. Further, the train control installation has a self-healing feature to maintain train service during an ABSU failure.
Owner:GHALY NABIL N

Process group resource manager

A process group resource manager for managing protected resources during transaction processing is disclosed. The process group resource manager comprises a first process configured to provide access to a protected resource during one or more transactions, the first process being further configured to construct a transaction record for each respective transaction, wherein each transaction record includes each request message received by the first process and each response message sent by the first process during a particular transaction. The process group resource manager further comprises a second process configured to serially replay the transactions in which the first process participates, the second process being configured to cause a particular transaction to rollback if the replay of that transaction does not match the transaction record constructed by the first process for that transaction. The process group resource manager also comprises a third process configured to store a durable image of the third process for use in reconstructing either the first process or the second process.
Owner:FLASH NETWORKS

Feed additive composition

A feed additive composition comprising a direct fed microbial in combination with a protease, and a phytase, and a method for improving the performance of a subject or for improving digestibility of a raw material in a feed (e.g. nutrient digestibility, such as amino acid digestibility), or for improving nitrogen retention, or for improving the subject's resistance to necrotic enteritis or for improving feed conversion ratio (FCR) or for improving weight gain in a subject or for improving feed efficiency in a subject or for modulating (e.g. improving) the immune response of the subject or for promoting the growth of beneficial bacteria in the gastrointestinal tract of a subject, which method comprising administering to a subject a direct fed microbial in combination with a protease and a phytase.
Owner:DUPONT NUTRITION BIOSCIENCES APS

Process for the Production of Carbon Graphenes and other Nanomaterials

Process for producing nanomaterials such as graphenes, graphene composites, magnesium oxide, magnesium hydroxides and other nanomaterials by high heat vaporization and rapid cooling. In some of the preferred embodiments, the high heat is produced by an oxidation-reduction reaction of carbon dioxide and magnesium as the primary reactants, although additional materials such as reaction catalysts, control agents, or composite materials can be included in the reaction, if desired. The reaction also produces nanomaterials from a variety of other input materials, and by varying the process parameters, the type and morphology of the carbon nanoproducts and other nanoproducts can be controlled. The reaction products include novel nanocrystals of MgO (percilase) and MgAl2O4 (spinels) as well as composites of these nanocrystals with multiple layers of graphene deposited on or intercalated with them.
Owner:GRAPHENE TECH

Compositions for delivering peptide YY and PYY agonists

The present invention provides a composition (e.g., a pharmaceutical composition) comprising at least one delivery agent compound and at least one of peptide YY (PYY) and a PYY agonist. Preferably, the composition includes a therapeutically effective amount of peptide YY or the PYY agonist and the delivery agent compound. The composition of the present invention facilitates the delivery of PYY, a PYY agonist, or a mixture thereof and increases its bioavailability compared to administration without the delivery agent compound. PPY and PYY agonists possess activity as agents to reduce nutrient availability, including reduction of food intake
Owner:NOVO NORDISK NORTH AMERICA OPERATIONS AS

Rechargeable Battery Management

ActiveUS20120038322A1Reduce electronic hardware requirementFast samplingElectric devicesElectric powerDigital down converterRechargeable cell
Systems and methods for adjusting sampling and switching rates of a battery management system are provided. For example, a rate at which different battery cells of a battery cell stack are in communication with an analog to digital converter may be adjusted in response to conditions of a battery cell.
Owner:A123 SYSTEMS LLC

Feed additive composition

A feed additive composition comprising a direct fed microbial in combination with a protease, a xylanase, an amylase and a phytase, and a method for improving the performance of a subject or for improving digestibility of a raw material in a feed (e.g. nutrient digestibility, such as amino acid digestibility), or for improving nitrogen retention, or for avoiding the negative effects of necrotic enteritis or for improving feed conversion ratio (FCR) or for improving weight gain in a subject or for improving feed efficiency in a subject or for modulating (e.g. improving) the immune response of the subject or for promoting the growth of beneficial bacteria in the gastrointestinal tract of a subject, which method comprising administering to a subject a direct fed microbial in combination with a protease, a xylanase, an amylase and a phytase.
Owner:DUPONT NUTRITION BIOSCIENCES APS

Data communications

In a data communications system a remote data source outputs data as a series of application data units (ADUs). Each ADU is individually encrypted with a different key. The keys are transmitted (for example using Internet multicasting) via a communications network to one or more customer terminals. At the terminals a sequence of keys is generated for use in decrypting the ADUs. A record is kept of the keys generated, and this record may subsequently be used to generate a receipt for the data received by the customer. The keys may be generated, and the record stored within a secure module such as a smartcard.
Owner:BRITISH TELECOMM PLC

Compositions and methods for regulation of active TNF- alpha

Substances comprising disaccharides and substances comprising carboxylated and / or sulfated oligosaccharides in substantially purified form, and methods of using same, are disclosed for the regulation of cytokine activity in a host. For instance, the secretion of active Tumor Necrosis Factor Alpha (TNF- alpha ) can be either inhibited or augmented selectively by administration to the host of an effective amount of a substance of the invention. Thus, the present invention also relates to pharmaceutical compositions and their use for the prevention and / or treatment of pathological processes involving the induction of active cytokine secretion, such as TNF- alpha . The invention also relates to the initiation of a desirable immune system-related response by the host to the presence of activators, including pathogens. The substances and pharmaceutical compositions of the present invention may be administered daily, at very low effective doses, typically below 0.1 mg / kg human, or at intervals of up to about 5-8 days, preferably once a week.
Owner:YEDA RES & DEV CO LTD

Dual-use micro encapsulation composition for hydrocarbons and detoxification of highly hazardous chemicals and substances

A two-component, water based micro encapsulation composition and method for the cleanup of hydrocarbon spills or contaminates on various surfaces and media. The two-part formulation includes a first solution including water in a predetermined ratio of a water soluble alkaline silicate solution having at least one alkali metal and a predetermined ratio of at least one water soluble surfactant; and a second solution including water, a predetermined ratio of water soluble acid, a predetermined ratio of water dispersible polymer, a predetermined ratio of water soluble hydrotrope, and a predetermined ratio of at least one water soluble flocculating agent. A method of using the two-part formulation includes preparing the two-part formulation, allowing the first solution to contact the hydrocarbon or chemical contaminate; allowing the second solution to contact the first solution and contaminate to form a homogeneous mixture; and removing the homogeneous mixture.
Owner:OIL SOLUTIONS INT

System and program for controlling electronic devices

A controlling system for an electronic peripheral device is provided. The controlling system comprises an electronic peripheral device having a plurality of communication interfaces and a plurality of functions, at least one terminal device connectable to one of the communication interfaces of the electronic peripheral device via one of communication networks so that the terminal device can use one of the plurality of functions based on as to through which communication interface an instruction from the terminal device is received when the at least one of the plurality of functions is determined to be available, a function availability setting system, by which availability of at least one of the plurality of functions to the terminal device is set, and a function execution controlling system which controls execution of the at least one of the plurality of functions based on as to through which communication interface the instruction is received.
Owner:BROTHER KOGYO KK
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