632 results about "Dimethylaniline" patented technology

The invention provides N-diethylaminoacetyl-2,6-dimethylaniline derivatives, a preparation method and applications thereof. The structure of the derivatives is represented by the formula (I). The preparation method comprises the following steps: carrying out reactions between N-diethylaminoacetyl-2,6-dimethylaniline and halogenated compounds to obtain a corresponding quaternary ammonium salt intermediate, and then subjecting the quaternary ammonium salt intermediate to react with corresponding 2-methoxyl-4-subsituted phenol derivative raw material so as to obtain the N-diethylaminoacetyl-2,6-dimethylaniline derivatives. The derivatives can be used as a long-acting local anesthetic drug or a pain relieving drug capable of separating the motion and the feeling, can exert a reversible and lasting local anesthetic effect in organism bodies, do not affect motor function in a certain dosage range, and have an ideal retardant effect on separation of motion and feeling.

An adhesive composition that includes a mixture of a cationically polymerizable component, an acidic component, and an initiator is provided. Preferably, the initiator comprises an iodonium salt, a visible light sensitizer, and an electron donor compound, wherein the initiator has a photoinduced potential greater than or equal to that of N,N-dimethylaniline in a standard solution of 2.9x10-5 moles / g diphenyl iodonium hexafluoroantimonate and 1.5x10-5 moles / g camphorquinone in 2-butanone. This adhesive composition is cationically polymerizable and is able to bond to hard tissue and cationic restorative materials upon curing.

The invention discloses a synthesis method of mefenamic acid. The method comprises the following steps: firstly adding o-halophenylacetic acid, 2,3-dimethylaniline, acid binding agent, catalyst and water in a reaction container to react; then adding water in the reaction mixture to dilute, then acidifying to ensure that the pH value is 2-3, cooling to the room temperature, filtrating, washing filter residue with warm water to obtain raw mefenamic acid; then adding the raw mefenamic acid in a reaction container, then adding organic solvent to perform recrystallization, filtrating to obtain solid, dissolving the obtained solid in organic solvent to perform second recrystallization, filtrating, and drying to obtain the target product. The synthesis method of mefenamic acid in the invention has the advantage that the production cost is low, the utilization of reaction raw materials is complete, the product purity is high, the environmental pollution is little, the operation safety is high, and the method is environmentally friendly and is applicable to industrial production.

The invention discloses flame-retarding lacquer putty and a preparation method thereof, and aims to provide air-dried organic silicon-modified unsaturated flame-retarding lacquer putty which has good comprehensive performance, long-term use at the temperature of below 250 DEG C and self-drying property at normal temperature to meet special requirements of subway vehicles and casthouse vehicles, wheel shafts, smoke (steam) passages and the like in other high temperature places. The air-dried organic silicon-modified unsaturated flame-retarding lacquer putty is characterized by being prepared by mixing raw material nano-montmorillonite not containing a halogen element compound, reactive diluent, a heat-resistant unsaturated polyester resin, an organic silicon resin, a special filler, a flame retardant, a low shrinkage additive, a stabilizer, dimethylaniline, a dispersant, titanium dioxide, hollow glass micro-beads, a drier, molybdenum disulfide, talcum powder, ketone peroxide, a curing agent filler, quinacridone bluish red and polyvinylpyrrolidone in a certain proportion, dispersing and grinding the mixture to prepare a main agent and a curing agent, and mixing the main agent with the curing agent. The flame-retarding lacquer putty is mainly used as a bottom coating material for subway vehicles.

The invention provides a fluorescent probe based on aggregation-induced emission characteristics and a method for determining critical micelle concentration by using the fluorescent probe and application of the fluorescent probe. The aggregation-induced emission dye has a structure as shown in a formula I in the description. According to the invention, the fluorescent probe is innovatively appliedto the critical micelle concentration detection of a surfactant, and the approximate value can be rapidly determined. When the AIE fluorescent probe is used for detecting the critical micelle concentration of the surfactant, the operation steps are simple, the application range is wide, and the critical micelle concentration of an anionic surfactant and a nonionic surfactant can be accurately determined. In the formula I, R1 is independently selected from any one of C1-C8 carboxyl, a sulfonic group, a phosphate group or a phosphite group, and n is equal to 0, 1, 2, 3, 4, 5, 6 or 7; and R2 isindependently selected from any one of methyl, methoxy, N,N-dimethyl, N,N-dimethylaniline, triphenylamine, hydroxyl, amino or sulfydryl.

A dry-sheet type serum creatinine detection reagent strip and a preparing method thereof are disclosed and belong to the field of in-vitro diagnosis. A creatinine reacting membrane, a filtering membrane and a diffusion layer in the reagent strip are fixed to a plastic plate in an appropriately overlapping manner. The reagent strip is characterized in that the reacting membrane includes a diluting liquid and a reacting reagent, the diluting liquid includes a buffer liquid, a surfactant, a stabilizer, an adhesive, a coenzyme factor and an aseptic, and the reacting reagent includes creatinine amidohydrolase, creatinase, sarcosine oxidase, peroxidase, 4-aminoantipyrine and N-ethyl-N-(2-hydroxy-3-sulfopropyl)-3,5-dimethylaniline. The Trinder reagent is utilized as an indicator probe, an analyte finally generates a colored quinone compound through various enzyme functions, and the creatinine content of a sample is indirectly detected through the coloration degree of the quinone compound. According to the reagent strip and the method, a liquid phase reaction is transferred to a solid carrier, objectives of simple operation and rapid and convenient detection of the creatinine content of the sample are achieved, and the reagent strip and the method are high in sensitivity, good in accuracy and convenient in popularization and application.

The invention relates to a preparation method of sulfadoxine, which comprises the following steps: (1) reacting methyl methoxyacetate and excessive diethyl oxalate to generate 3-methoxy-2-oxo-methylethyl succinate, and decarbonylating to obtain 2-methoxy-methylethyl malonate; (2) reacting the 2-methoxy-methylethyl malonate and formamide to generate a cyclocompound; (3) carrying out chlorination reaction; (4) carrying out condensation reaction; and (5) carrying out methoxylation reaction. The purity of the 2-methoxy-methylethyl malonate obtained in the step (1) is strictly controlled, and the cyclocompound in the step (2) is controlled to exist in the form of anhydrous hydroxy sodium salt; in the step (3), no catalyst, including N,N-dimethylaniline, is used; and in the step (5), solid sodium hydroxide is substituted for sodium methoxide solution. The invention is easy to operate, has the advantage of high product quality, greatly lowers the production cost, and has obvious economic benefit and environmental benefit.