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41 results about "Umbelliferone" patented technology
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Umbelliferone, also known as 7-hydroxycoumarin, hydrangine, skimmetine, and beta-umbelliferone, is a natural product of the coumarin family. It absorbs ultraviolet light strongly at several wavelengths. Despite several indications that this chemical is photomutagenic, it is used in sunscreens. Umbelliferone has been reported to have antioxidant properties.
Inhibitors and Enhancers of Uridine Diphosphate-Glucuronosyltransferase 2B (UGT2B)
ActiveUS20090074708A1Increase heightReduced activityBiocideHydroxy compound active ingredientsPolyethylene glycolEriodictyol
A UGT2B inhibitor capable of increasing the bio-availability of a drug, is a compound in a free base or a pharmaceutically acceptable salt form that is selected from the group consisting of: capillarisin, isorhamnetin, β-naphthoflavone, α-naphthoflavone, hesperetin, terpineol, (+)-limonene, β-myrcene, swertiamarin, eriodictyol, cineole, apigenin, baicalin, ursolic acid, isovitexin, lauryl alcohol, puerarin, trans-cinnamaldehyde, 3-phenylpropyl acetate, isoliquritigenin, paeoniflorin, gallic acid, genistein, glycyrrhizin, protocatechuic acid, ethyl myristate, umbelliferone, PEG (Polyethylene glycol) 400, PEG 2000, PEG 4000, Tween 20, Tween 60, Tween 80, BRIJ® 58, BRIJ® 76, Pluronic® F68, Pluronic® F127, and a combination thereof. A UGT2B enhancer capable of enhancing a clearance rate of morphine-like analgesic agents, is a compound in a free base or a pharmaceutically acceptable salt form that is selected from the group consisting of: nordihydroguaiaretic acid, wogonin, trans-cinnamic acid, baicalein, quercetin, daidzein, oleanolic acid, homoorientin, hesperetin, narigin, neohesperidin, (+)-epicatechin, hesperidin, liquiritin, eriodictyol, formononetin, quercitrin, genkwanin, kaempferol, isoquercitrin, (+)-catechin, naringenin, daidzin, (−)-epicatechin, luteolin-7-glucoside, ergosterol, rutin, luteolin, ethyl myristate, apigenin, 3-phenylpropyl acetate, umbelliferone, glycyrrhizin, protocatechuic acid, poncirin, isovitexin, 6-gingerol, cineole, genistein, trans-cinnamaldehyde, and a combination thereof.
Owner:NAT DEFENSE MEDICAL CENT
Efficient, low-toxic and environment-protective plant insect-killing extract
InactiveCN101069702ASimple chemical structureEasy to synthesizeBiocideAntiparasitic agentsActive componentPlant Sources
The present invention relates to a high-effective, low-toxicity and environment-protecting new-type plant source pesticide and miticide new medicine. The invented plant extract includes capillaries industrial alcohol extract and capillaries n-butyl alcohol extract, the pesticide and medicide active component of said capillaries alcohol extract is 4-methyl-7-umbelliferone. Besides, said invention also provides its preparation method and its concrete steps.
Owner:NORTHWEST A & F UNIV
Self-indicating photo-repatternable hybrid materials and polymers
In some embodiments, the present invention is directed to a method for chemically modifying 7-substituted coumarins to produce polymerizable monomers that are used to prepare photoresponsive materials. In one embodiment, 7-hydroxy-coumarin (umbelliferone) is so modified. The present invention also relates to the photoresponsive linear polymers, copolymers, and hybrid network materials produced from the polymerizable monomers, and the method for their preparation.
Owner:RGT UNIV OF CALIFORNIA
Fluorescent polymers of 7-hydroxycoumarin compounds, chemical sensors comprising them, and polymerizable fluorescent compound of 7-hydroxycoumarin
InactiveUS20120178172A1Easy to aggregateOrganic chemistryChemiluminescene/bioluminescenceAcetic acidMethacrylate
Polymers and copolymers of polymerizable fluorescent compounds of 7-hydroxycoumarin such as Ethyl-2-methacrylate Umbelliferone-4-acetate are provided. In addition, a sensor comprising this polymer notably for detecting and / or assaying nitrated and organophosphorus compounds, explosives, and toxic compounds is provided.
Owner:COMMISSARIAT A LENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES
Pseudomonas aeruginosa chromogenic culture medium and method for quick detection by same
PendingCN110129406AThe difference is obviousStrong specificityMicrobiological testing/measurementBiological material analysisNalidixic acidUltraviolet
The invention relates to the technical field of pseudomonas aeruginosa detection and discloses a pseudomonas aeruginosa chromogenic culture medium and a method for quick detection by the same. The pseudomonas aeruginosa chromogenic culture medium comprises a basic medium, a chromogenic substrate and an antibacterial agent. The chromogenic substrate comprises 2,3,5-phenyl tetrazolium chloride, 4-methyl umbelliferone-D-glucuronide, and the antibacterial agent comprises nalidixic acid, cycloserine and bile salt. 2,3,5-phenyl tetrazolium chloride acts on a pseudomonas aeruginosa metabolite to showa red color; 4-methyl umbelliferone-D-glucuronide acts on pseudomonas aeruginosa to show fluorescence under a 366nm ultraviolet lamp; by joint action of 2,3,5-phenyl tetrazolium chloride and the antibacterial agent, growth of common disturbance bacteria can be inhibited, and false positive results are avoided. By adoption of the pseudomonas aeruginosa quick detection method, detection and count of pseudomonas aeruginosa can be finished in 24h, and time saving, labor saving, stability, reliability and high sensitivity are realized.
Owner:上海源本食品质量检验有限公司
Fluorescent polymers of 7-hydroxycoumarin compounds, chemical sensors comprising them, and polymerizable fluorescent compound of 7-hydroxycoumarin
InactiveUS8993700B2Easy to aggregateOrganic chemistryChemiluminescene/bioluminescenceMethacrylateAcetic acid
Polymers and copolymers of polymerizable fluorescent compounds of 7-hydroxycoumarin such as Ethyl-2-methacrylate Umbelliferone-4-acetate are provided. In addition, a sensor comprising this polymer notably for detecting and / or assaying nitrated and organophosphorus compounds, explosives, and toxic compounds is provided.
Owner:COMMISSARIAT A LENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES
Carbon dot fluorescent probe, and preparation method and application thereof
PendingCN110982514AHigh selectivityImprove specific recognitionFluorescence/phosphorescenceLuminescent compositionsFluoProbesHybrid material
The invention discloses a preparation method of a carbon dot fluorescent probe. The method comprises the following steps: stirring and dispersing an umbelliferone derivative and amino acids in an aqueous solution, performing a reaction at 180-200 DEG C for 12-15 h, centrifuging the obtained suspension to remove large particles, filtering the obtained supernatant by a 0.22-0.25 [mu]m filter membrane to thoroughly remove the large particles, and dialyzing and freeze-drying the filtered supernatant to obtain the product. The probe can realize high-sensitivity and high-selectivity detection of Fe<3+>. The synthesis strategy of the carbon dot hybrid material is provided, a new way is opened up for ion detection, and high-selectivity and specific recognition of iron ions in a water phase is realized.
Owner:THE SECOND RES INST OF CIVIL AVIATION ADMINISTRATION OF CHINA
Radix peucedani health tea and preparation method thereof
InactiveCN104938696ADispersing wind and clearing heatXiefei and asthmaPre-extraction tea treatmentAdditive ingredientTraditional medicine
The invention discloses radix peucedani health tea and a preparation method thereof, and relates to the technical field of health maintenance tea processing. The radix peucedani health tea is obtained by processing raw materials including tea leaves, radix peucedani, white mulberry root-bark, fritillaria and radix glycyrrhizae through the eight steps of radix peucedani leaf picking, fresh tea leaf picking, radix peucedani root processing, blending and soaking, rolling, fermentation, stir-frying and packaging. The tea leaves and radix peucedani are used as main materials, radix peucedani leaves containing beneficial components such as nodakenin, decursitin and umbelliferone are soaked in radix peucedani root wine decocted liquid together with fresh tea leaves, functional components in radix peucedani are fully absorbed, and therefore slight enzymatic reaction is achieved, the effective components of radix peucedani are reasonably blended in the tea leaves, and the prepared health tea has the effects of removing wind, releasing heat, depressing qi and reducing phlegm.
Owner:NINGDE MINGDING TEA IND CO LTD
Cooling agent and synthesis method thereof
InactiveCN102381936ACool and mildLong durationTobacco treatmentOrganic compound preparationAlcoholHydrogen
The invention relates to a cooling agent and a synthesis method thereof. The synthesis method of the cooling agent comprises the following steps of 1, cleaning up a reactor by an ethanol solution, and removing air in the reactor, 2, adding an ethanol solution as a reaction solvent, umbelliferone and a Pd / C catalyst into the reactor, feeding hydrogen into the reactor, and heating for a reaction lasting for 6 to 8 hours, and 3, removing the Pd / C catalyst, adding NaBH4 into the product obtained by the step 2 for a sequential reaction, acidizing the reacted mixture obtained by the sequential reaction, carrying out extraction by ether to obtain extract, and carrying out reduced pressure distillation of the extract to obtain the cooling agent, wherein the cooling agent comprises four 1-isopropyl-4-methylbicyclo[3.1.0]-hexyl-2-alcohol structural isomers. The cooling agent has a gentle cool taste, long time of duration, obviously low irritation on the laryngeal, an obviously slight dry sensation, and a very strong moistening feel.
Owner:HUABAO FLAVOURS & FRAGRANCES CO LTD
Application of umbelliferone in preparing anti-eimeria tenella medicine
ActiveCN103565799AGood against Eimeria tenellaAntiparasitic agentsHeterocyclic compound active ingredientsBiotechnologyWater soluble
The invention discloses an application of umbelliferone in preparing an anti-eimeria tenella medicine. The umbelliferone and an acceptable auxiliary material are prepared as powder which is added into feed and uniformly mixed and is used for feeding chicken according daily feed amount. Or, the umbelliferone is prepared as umbelliferone water soluble powder which is dissolved in water and is used for feeding chicken according to daily water consumption. Animal infection experiments verify that the anticoccidial index (ACI) of the umbelliferone can reach over 165, and the umbelliferone has a better anti-eimeria tenella effect.
Owner:INST OF ANIMAL HEALTH GUANGDONG ACADEMY OF AGRI SCI
Inhibitors and enhancers of uridine diphosphate-glucuronosyltransferase 2b (UGT2B)
InactiveUS20160184298A1Increase heightReduced activityBiocideMetabolism disorderPolyethylene glycolEriodictyol
A UGT2B inhibitor capable of increasing the bio-availability of a drug, is a compound in a free base or a pharmaceutically acceptable salt form that is selected from the group consisting of: capillarisin, isorhamnetin,β-naphthoflavone, α-naphthoflavone, hesperetin, terpineol, (+)-limonene, β-myrcene, swertiamarin, eriodictyol, cineole, apigenin, baicalin, ursolic acid, isovitexin, lauryl alcohol, puerarin, trans-cinnamaldehyde, 3-phenylpropyl acetate, isoliquritigenin, paeoniflorin, gallic acid, genistein, glycyrrhizin, protocatechuic acid, ethyl myristate, umbelliferone, PEG (Polyethylene glycol) 400, PEG 2000, PEG 4000, Tween 20, Tween 60, Tween 80, BRIJ® 58, BRIJ® 76, Pluronic® F68, Pluronic® F127, and a combination thereof. A UGT2B enhancer capable of enhancing a clearance rate of morphine-like analgesic agents, is a compound in a free base or a pharmaceutically acceptable salt form that is selected from the group consisting of: nordihydroguaiaretic acid, wogonin, trans-cinnamic acid, baicalein, quercetin, daidzein, oleanolic acid, homoorientin, hesperetin, narigin, neohesperidin, (+)-epicatechin, hesperidin, liquiritin, eriodictyol, formononetin, quercitrin, genkwanin, kaempferol, isoquercitrin, (+)-catechin, naringenin, daidzin, (−)-epicatechin, luteolin-7-glucoside, ergosterol, rutin, luteolin, ethyl myristate, apigenin, 3-phenylpropyl acetate, umbelliferone, glycyrrhizin, protocatechuic acid, poncirin, isovitexin, 6-gingerol, cineole, genistein, trans-cinnamaldehyde, and a combination thereof.
Owner:NAT DEFENSE MEDICAL CENT
Low side effect pharmaceutical composition containing isoniazid
ActiveUS8304394B2Reduce INH-induced side-effectsEliminate side effectsAntibacterial agentsBiocideDaidzeinDiosmin
The present invention features a novel, low side-effect pharmaceutical compound complex, comprising the pharmaceutically effective dose of isoniazid (INH) and pharmaceutically effective dose of one of the following compounds. Said compound was selected from the following groups of compounds: Nordihydroguaiaretic acid, Trans-Cinnamaldehyde, Daidzein, Isovitexin, Kaempferol, disulfuram, β-Myrcene, Quercetin, (−)-Epigallocatechin-3-gallate, (+)-Limonene, Myricetin, Quercitrin, Luteolin-7-Glucoside, Morin, Neohesperidin, Hesperidin, Capillarisin, (−)-Epigallocatechin, Luteolin, Hyperoside, Ethyl Myristate, Tamarixetin, Phloretin, Baicalein, Rutin, Baicalin, Apigenin, Naringenin, Hesperetin, (+)-Epicatechin, (−)-Epicatechin-3-gallat, Isoliquritigenin, Silybin, Vitexin, Genistein, Isorhamnetin, gallic acid, Diosmin, 6-Gingerol, (+)-Taxifolin, Wongonin, Protocatechuic acid, (+)-Catechin, β-naphthoflavone, Embelin, Trans-Cinnamic acid, (−)-Epicatechin, Phloridzin, Puerarin, Umbelliferone, Brij 58, Brij 76, Brij 35, Tween 20, Tween 80, Tween 40, PEG 2000, PEG 400, Pluornic F68, and PEG 4000. The novel, low side-effect compound complex which contains pharmaceutically effective doses of isoniazid (INH), disulfuram (DSF) and / or a third compound, bis-nitrophenyl phosphate (BNPP) can reduce isoniazid (INH)-induced side effects, e.g. hepatotoxicity, etc.
Owner:INT EDUCATION FOUND
Tobacco flavor capable of reducing hazardous substance in smoke and bobbin paper containing same
The invention provides tobacco flavor capable of reducing hazardous substance in smoke and a preparation method thereof. The invention further provides application of tobacco flavor in bobbin paper. Adopted celery seeds have pleasant strong fragrance and acrid and bitter taste, and can cover up the woodiness and scorch smell in bobbin paper made in China and improve smoking flavor of cigarettes after being combined with vitexin, umbelliferone and maltol; meanwhile, by adopting the specific production technology, the content of nitrosamine in smoke can be reduced, and therefore harm of smoke to the human body is reduced. Compared with the prior art, after bobbin paper is sprayed with the tobacco flavor, the woodiness and scorch smell in bobbin paper made in China are covered, simulation of the bobbin paper made in China is reduced, and the smoking flavor of the cigarettes is good. The content of the harmful ingredient nitrosamine in smoke can be reduced, and harm of smoke to the human body is reduced.
Owner:CHINA TOBACCO JIANGXI IND CO LTD
Application of umbelliferone in preparing composition for resisting skin photoaging
InactiveCN113244226AIncrease vitalityInhibit apoptosisCosmetic preparationsToilet preparationsInflammatory factorsUvb irradiation
The invention relates to the technical field of application of umbelliferone, and in particular relates to application of umbelliferone in preparing a composition for resisting skin photoaging. The invention discloses application of umbelliferone in preparing the composition for resisting skin photoaging. According to the invention, experiments prove that the umbelliferone can significantly improve the cell activity after UVB irradiation; cell apoptosis induced by UVB and secretion of cell inflammatory factors are inhibited; the expression of MMP-1 and MMP-9 induced by the UVB is reduced; and inhibition of apoptosis and activation of NF-kappa B and MAPK signal channels proves that umbelliferone is an effective substance for resisting skin photoaging.
Owner:北京温适宝科技有限公司
Composition for preventing and controlling gray mold of ginseng and bactericide prepared by same
InactiveCN108450479AReduce usageDelay and/or prevent resistanceBiocideFungicidesGraphenePathogenic bacteria
The invention discloses a composition for preventing and controlling the gray mold of ginseng and a bactericide prepared by the composition. The composition comprises the following components in percentages by weight: 40% to 70% of difenoconazole, 20% to 50% of umbelliferone and 0.1% to 15% of oxidized graphene. According to the composition for preventing and controlling the gray mold of ginseng disclosed by the invention, difenoconazole, plant extract difenoconazole and oxidized graphene are blended, within a specific proportional region, a synergistic effect is developed among the three components mutually, the blended composition has extremely high inhibitory activity for the gray mold of ginseng while the using amount of difenoconazole is reduced, and the inhibiting effect is equivalent to that of single-dose difenoconazole. The blended composition is used after being prepared into the bactericide, the gray mold of ginseng can be prevented and controlled effectively, simultaneouslythe using amount of difenoconazole also can be reduced, and the resistance of pathogenic bacteria of the gray mold of ginseng for difenoconazole is retarded and / or prevented.
Owner:林荣铨
Staphylococcus aureus fluorescent chromogenic culture medium
InactiveCN107723336ASimplify the Chromogenic Culture ProcessMicrobiological testing/measurementMicroorganism based processesStaphylococcus cohniiFluorescence
The invention discloses a fluorescent chromogenic culture medium for detecting staphylococcus aureus. The fluorescent chromogenic culture medium is prepared from a nitrogen source, a carbon source, sodium chloride and an infectious microbe growth inhibitor. The fluorescent chromogenic culture medium is characterized by further being prepared from staphylococcus aureus chromogenic substrate 4-methyl umbelliferone-p-nitro beta-D-glucoside and beta-D-glucoside, non staphylococcus aureus chromogenic substrate paranitrophenol-alpha-D-galactopyranose and non staphylococcus aureus chromogenic substrate p-nitrophenol beta-D-glucuronide. The fluorescent chromogenic culture medium disclosed by the invention can provide a more convenient chromogenic scheme for distinguishing the staphylococcus aureusfrom other staphylococcus under the situation without color developing aid existence, can effectively distinguish the staphylococcus aureus from a part of non staphylococcus aureus and other infectious microbes and has a better selectivity to the staphylococcus aureus.
Owner:黄增才
Evaluation of the severity of patients with flavivirus infection by blood hyaluronan levels and therapeutic agents to block the hyaluronan
The present invention discloses a method to determine whether a warning sign will occur in a subject with the Flavivirus infectious illness, and a pharmaceutical composition. The method includes steps of measuring the level of serum hyaluronan of the subject, and determining that the warning sign will occur in his / her illness course when the level is higher than or equal to 70 ng / mL. It is identified in the invention that the level of the serum hyaluronan is an excellent predicator for the severity of the Flavivirus infectious illness. The pharmaceutical composition is used for blocking the serum hyaluronan of the Flavivirus-infected subjects to prevent inflammation, and includes a therapeutically effective amount of a 4-methyl umbelliferone sodium salt, a CD44 siRNA, an anti-CD44 antibody or a hyaluronidase, wherein the therapeutically effective amount is an effective blood concentration of the 4-methyl umbelliferone sodium salt, the CD44 siRNA, the anti-CD44 antibody, and the hyaluronidase of the subject being in a range from 0.05 mM to 5 mM, 1 nM to 100 nM, 5 μg / ml to 500 μg / ml and 0.5 unit / mL to 50 units / mL, respectively.
Owner:KAOHSIUNG MEDICAL UNIVERSITY
Method for detecting effective components of girald daphne bark
The invention discloses a method for detecting effective components of girald daphne bark. The method includes the steps of firstly, preparing a reference substance solution, wherein a mixed solution containing daphnetin and umbelliferone is prepared from daphnetin and umbelliferone reference substances; secondly, preparing a test article solution, wherein girald daphne bark tablets are taken to be fine ground, solvent is added, ultrasonic treatment is conducted, and then filtering is conducted to obtain subsequent filtrate; thirdly, conducting detecting, wherein the reference substance solution and the test article solution are taken to be injected into a liquid chromatograph, a chromatogram is obtained, and the contents of the corresponding components in a test article are calculated according to the chromatogram.
Owner:QINHUANGDAO SHANHAIGUAN PHARMA CO LTD
Composite for preventing and treating gray mold of cucurbita pepo and bactericide prepared by composite
InactiveCN108576013AStrong inhibitory activityReduce usageBiocideFungicidesGrapheneInhibitory effect
The invention discloses a composite for preventing and treating gray mold of cucurbita pepo and a bactericide prepared by the composite. The composite is prepared from, by mass, 50-80% of difenoconazole, 10-40% of umbelliferone and 1-15% of oxidized graphene. According to the composite for preventing and treating gray mold of cucurbita pepo, difenoconazole, a plant extract (umbelliferone) and oxidized graphene are mixed, and the three components achieve synergism within a specific proportion range; the mixed composite reduces the dosage of difenoconazole and meanwhile has great inhibition activity on gray mold of cucurbita pepo, wherein the inhibition activity is equivalent to that of a single agent (difenoconazole). After the mixed composite is made into the bactericide for use, gray moldof cucurbita pepo can be effectively prevented and treated, the dosage of difenoconazole can also be reduced at the same time, and the situation is slowed down and / or avoided that pathogenic bacteriaof gray mold of cucurbita pepo has resistance to difenoconazole.
Owner:林荣铨
Drug combination
The invention relates to a drug combination and belongs to the field of medicines. The drug combination comprises, by weight, 5-30 parts of umbelliferone, 5-20 parts of 7-hydroxy-8-methoxycoumarin, 2-20 parts of 8-hydroxy-7-methoxycoumarin, 5-20 parts of luteolin, and 5-20 parts of 4', 7-dyhydroxy-5-methoxyflavone. The drug combination is used for preparing anti-inflammatory, analgesic and antiviral drugs. Dosage of active substances of the anti-inflammatory, analgesic and antiviral drug combination can be changed according to age and weight of patients, disease severity and other like factors, and 50mg-100mg is taken orally for twice a day.
Owner:吉林圣亚医药科技有限公司
Composition for prevention and control of actinidia chinensis gray mold and fungicide prepared therefrom
The invention discloses a composition for prevention and control of actinidia chinensis gray mold and a fungicide prepared therefrom. The composition comprises the following components by mass percentage: 40%-80% of difenoconazole, 15%-50% of umbelliferone, and 1%-15% of graphene oxide. According to the composition for prevention and control of actinidia chinensis gray mold provided by the invention, difenoconazole, the plant extract umbelliferone and graphene oxide are compounded, within a specific proportion range, the three components play a synergistic role cooperatively, while the dosageof difenoconazole is lowered, good inhibitory activity of the composition on strawberry gray mold can be guaranteed, and the inhibiting effect is equivalent to that of the single agent difenoconazole.The mixed composition can be prepared into a fungicide for use, and the fungicide can effectively prevent and control actinidia chinensis gray mold, at the same time can reduce the dosage of difenoconazole, and slow down and / or prevent the actinidia chinensis gray mold pathogens from producing resistance to difenoconazole.
Owner:林荣铨
Medicine for treating tropical theileriosis and application
ActiveCN111888354AGood treatment effectReduce lossesAntiparasitic agentsHeterocyclic compound active ingredientsMedicinePharmaceutical drug
The invention provides a medicine for treating tropical theileriosis. The effective component of the medicine is 4-methyl umbelliferone. The medicine disclosed by the invention has a good treatment effect on the tropical theileriosis, the recovery rate reaches 92.3% and is superior to that of the existing medicine triazamidine, the loss of farmers is reduced, and the economic benefits of the sheepfarmers are improved.
Owner:LANZHOU INST OF ANIMAL SCI & VETERINARY PHARMA OF CAAS
Composite for preventing and treating gray mold of tobacco and bactericide prepared by composite
InactiveCN108576014AStrong inhibitory activityReduce usageBiocideFungicidesGraphenePathogenic bacteria
The invention discloses a composite for preventing and treating gray mold of tobacco and a bactericide prepared by the composite. The composite is prepared from, by mass, 50-75% of difenoconazole, 10-40% of umbelliferone and 0.1-20% of oxidized graphene. According to the composite for preventing and treating gray mold of tobacco, difenoconazole, a plant extract (umbelliferone) and oxidized graphene are mixed, and the three components achieve synergism within a specific proportion range; the mixed composite reduces the dosage of difenoconazole and meanwhile has great inhibition activity on graymold of tobacco, wherein the inhibition activity is equivalent to that of a single agent (difenoconazole). After the mixed composite is made into the bactericide for use, gray mold of tobacco can beeffectively prevented and treated, the dosage of difenoconazole can also be reduced at the same time, and the situation is slowed down and / or avoided that pathogenic bacteria of gray mold of tobacco has resistance to difenoconazole.
Owner:林荣铨
Method for determining content of umbelliferone in traditional Chinese medicine levisticum
The invention discloses a method for detecting umbelliferone in a traditional Chinese medicine levisticum by reversed phase high-performance liquid chromatography. The method is characterized by comprising the following steps of: carrying out ultrasonic extraction of umbelliferone in the traditional Chinese medicine levisticum by the use of methanol, and preparing a test solution; absorbing the test solution and injecting into high performance liquid chromatograph, determining by reversed phase high-performance liquid chromatography, using C18 column which takes octadecylsilane chemically bonded silica as a filler, using acetonitrile water as a mobile phase, detecting under 345nm at the flow velocity of 1 ml / min with the column temperature of 25 DEG C, carrying out qualitative analysis according to retention time and chromatogram of a sample, and carrying out quantitative analysis according to peak area. The method provided by the invention is simple to operate, has high precision and good reappearance, and can be used to detect umbelliferone in the traditional Chinese medicine levisticum.
Owner:SHANGHAI BAINIAN SHIDANDE INSPECTION TECH
A kind of attractant for A. aeruginosa beetle
The invention discloses an attractant for A. aeruginosa beetles, which belongs to the technical field of insect control. The attractant has a core-shell structure, including an outer shell layer and an inner core layer; the inner core layer is divided into two parts, and the two parts are separated. Some include: methyl eugenol, beta-ionol, vanillyl alcohol, brown sugar, myrcene, ethanol, andrographolide, nerol, benyl phenylacetate, cis-3-hexenyl alcohol, and 4-methyl Umbrella ketone-β-D galactoside, the second part is β-galactosidase; the shell layer is gelatin, and the attractant of the present invention has a strong ability to trap Aeruginosa aeruginosa beetles, good stability and strong specificity , and will not cause the Verdigris Beetle to develop resistance.
Owner:贵州省核桃研究所
A kind of 1,2,4-triazine-coumarin type compound and its preparation method and application
The invention discloses a 1, 2, 4-triazine-coumarin compound and a preparation method and application thereof. The compound is of the structure as indicated in the formula (I), and the preparation method comprises the steps that 7-umbelliferone and epoxy chloropropane serve as raw materials, 7-(oxirane-2-methoxyl)-2H-benzopyran-2-ketone is obtained, 1, 2-diphenylethane-1, 2-diketone and thiosemicarbazide serve as raw materials, 5, 6-diaryl-1, 2, 4-triazine-3-thioalcohol is obtained, and finally 7-(oxirane-2-methoxyl)-2H-benzopyran-2-ketone reacts with all types of 5, 6-diaryl-1, 2, 4-triazine-3-thioalcohol, so that the target compound is obtained. The compound can serve as the raw material of anti-diabetic medicine, the preparation method is simple, raw materials are easy to obtain, and operation is convenient.
Owner:南京润瞳畅达医药科技有限公司
Efficient, low-toxic and environment-protective plant insect-killing extract
InactiveCN101069702BSimple chemical structureEasy to synthesizeAntiparasitic agentsPlant ingredientsEuropean rabbitAdditive ingredient
The present invention relates to a high-effective, low-toxicity and environment-protecting new-type plant source pesticide and miticide new medicine. The invented plant extract includes capillaries industrial alcohol extract and capillaries n-butyl alcohol extract, the pesticide and medicide active component of said capillaries alcohol extract is 4-methyl-7-umbelliferone. Besides, said invention also provides its preparation method and its concrete steps.
Owner:NORTHWEST A & F UNIV
Application of umbelliferone in preparation of medicine for treating vaginitis
The invention discloses application of umbelliferone in preparation of a medicine for treating vaginitis, and experiments prove that umbelliferone has an inhibition effect on fungi and bacteria causing vaginitis.
Owner:GUANGDONG PHARMA UNIV
Preparation method of Ainsliaea lactone substances
The invention discloses a preparation method of Ainsliaea lactone substances. The lactone substances mainly comprise umbelliferone, Ainsliaea terpene, ainsliadimer A, gochatiolide A and the like. The invention particularly discloses the method for obtaining the Ainsliaea lactone substances by separating from Ainsliaea plants. The method comprises the following steps of raw material grinding, supercritical extraction, activated carbon decolorization, solvent extraction, dehydration, drying and the like so that the Ainsliaea lactone substances are finally obtained, wherein the total content of the umbelliferone, the Ainsliaea terpene, the ainsliadimer A and the gochatiolide A reaches above 60%.
Owner:NANJING ZELANG MEDICAL TECH
Quality testing method of Baihe Ganoderma lucidum
InactiveCN103454359BPerfect quality control systemIntrinsic qualityComponent separationRhinacanthus nasutusRepeatability
Owner:GUANGXI UNIV OF CHINESE MEDICINE
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