107 results about "Carthamin" patented technology

The invention relates to an action of ferulic acid on enhancing the drug effect of some medicaments and a purpose thereof, wherein the medicaments mainly comprise alkaloid medicaments including matrine, kushenin, sophocarpine, hyoscyamine, narceine, hanfangchin A, jamaicin, morphine, codeine, evodiamine, strychnine, catharanthine, vincristine, taxol, verticine, peimine, peiminine, ephedrine, pseudoephedrine, wilfordine, triptolide, tripdiolide and the like, and flavonoid medicaments including puerarin, ginsenoside, ginsengenin, mangiferin, scutelloside, alkannin, meletin, rutin, hesperidin, daidzin, soybean isoflavone, daidzein, carthamin, catechin and the like. The ferulic acid and the medicaments can form a compound or a medicament compound, or the ferulic acid and the medicaments can generate a chemical reaction (including salification, esterification, amidation, ketonization, etherification and the like), and / or the ferulic acid and the medicaments can generate a synergistic effect and an additive effect.

A safflower lyochrome rich is carthamin A (80-100%) and its preparing process and application to preparation of medicines to prevent and cure cardiovascular and cerebrovascular ischemia, and its medicines and preparing process are also disclosed.

The invention relates to a method for simultaneously extracting carthamin yellow and carthamin from safflower. The method comprises the following steps of: drying and sterilizing the safflower which serves as a raw material by using microwave at a low temperature to obtain a safflower material; leaching the safflower material for several times by taking water as a solvent; performing solid-liquid separation to obtain carthamin yellow extract; leaching a solid insoluble substance by using alkaline buffer solution to obtain carthamin extract; and finally performing reverse osmosis concentration on the carthamin yellow extract and the carthamin extract respectively, and freeze-drying to obtain a carthamin yellow and carthamin product. The method has the advantages of simple extraction process, easiness of operation, high extraction rate and convenience of industrial production, and the utilization value of the safflower can be greatly improved after the obtained product is used for dyeing.

The invention discloses application of bioflavonoids or polyphenol compounds to preventing and treating Parkinson diseases. The bioflavonoids or polyphenol compounds can be selected from kaempferol-3-O-rutinoside, dehydrated carthamin yellow B, 6-hydroxyl kaempferol-3, 6-dioxygen glucoside, (2S)-4', 5-dihydroxyl-6, 7-dioxygen flavonone glucoside, rutin, quercetin, vanillina or isovanillin. Through large amount of experiments, the bioflavonoids or polyphenol compounds have activity of interacting with protein DJ-1 related to the Parkinson diseases. Through further experiments, the bioflavonoids or polyphenol compounds have pharmaceutical activities for resisting oxidative stress, preventing apoptosis of PC12 cells or primary nerve cells induced by the oxidative stress, inhibiting active oxygen generation in cells, improving activity of tyrosine hydroxylase, and the like, and can be used for preventing or treating the Parkinson diseases.

The invention provides a natural pigment composition. The composition comprises an emulsifier, and two or more than two pigments selected from gardenia yellow pigment, curcumine, carthamin yellow, orange yellow pigment, xanthophylls, riboflavin, capsanthin, monascus red pigment, anattotree orange pigment and gardenia blue pigment. All the above natural pigments can be blended according to an arbitrary ratio to obtain the natural pigment composition with different color systems and different tones, such as yellow, orange, red, green and purple. The natural pigment composition contains the emulsifier, so the composition is uniform and stable. The combination of different natural pigments in the natural pigment composition makes up the defect of single pigments, for example, the light resistance of the natural yellow pigment composition obtained by combining riboflavin and curcumine with poor light resistance with stable gardenia blue pigment is better than that of riboflavin or curcumine, so the use amount is reduced, and the cost is reduced.

The invention discloses a fingerprint atlas analyzing method; which is characterized by the following: adding buffer in the inversed-phase chromatogram system for west carthamin; possessing stable chemical property for west carthamin-1, west carthamin-2, west carthamin-4 in the flow phase; displaying precise quantitative property and stable reserving time for west carthamin-3; satisfying the request of fingerprint atlas analysis.

The invention discloses a Dendrobium officinale Kimura et Migo-tea-vinegar beverage. The beverage comprises Dendrobium officinale Kimura et Migo fresh strips, Baimao tea, the root bark of the peony tree, pseudo-ginseng, herba eupatorii, divaricate saposhnikovia root, semen plantaginis, mint, fructus forsythia, root bark of white mulberry, rhizoma anemarrhenae, sweet osmanthus, malt vinegar, polyacryl pyrrolidone, hydroxypropyl methylcellulose sodium, potassium polyacrylate , sodium alginate, an American DuPont EEA2112AC compatilizer, a food-grade antioxidant potassium erythorbate, xanthan gum, carthamin yellow, nisin, maltose, starch sugar, acesulfame potassium, xylitol, vitamin E, vitamin K, vitamin PP, alanine, glutamic acid, aspartic acid, glycine, iron element, selenium element, cobalt element, zinc element, propyl-furfuryl fumarate, guanosine-5'-monophosphate disodium salt, glycine, carvone, dihydrojasmone, isoamyl acetate and 2-hexenol. The beverage can effectively treat or relieve halitosis symptoms.

The invention relates to a preparation method of safflower yellow B and the application thereof. The safflower is extracted after immersion and diacolation in polar solvent and is then treated with refinement and separation by a method of combining chromatographic column and alcohol precipitation so as to obtain the safflower yellow B of the invention. The preparation method for the safflower yellow B of the invention can improve the yield of the safflower yellow B and is applicable to commercial production. In addition, the safflower yellow B obtained after separation can be used for preventing and curing cardiovascular and cerebrovascular diseases.

The invention relates to the technical field of premix wines, in particular to natural herbal premix wine and a production method thereof; the natural herbal premix wine, per 100 L, comprises, by weight, 100-150 g of ginseng extract, 90-120 g of wolfberry fruit extract, 10-20 g of kudzuvine root extract, 10-20 g of Maca extract, 100-150 g of Guarana extract, 30-40 kg of high fructose corn syrup, 20-40 kg of white granulated sugar, 0.5-2 kg of citric acid monohydrate, 0.5-1 kg of malic acid, 500-1000 mL of natural fruit flavor, 100-150 g of carthamin yellow, 50-70 L of 70 v / w base wine, CO2 of 3-5 kg, 8-12L of apple juice and the balance of purified water; the natural herbal premix wine has bright yellow color and mild body, is sour and sweet, has cool aftertaste, has fruit aroma, medicinal aroma and liquor aroma, has unique flavor, is a low-ABV alcoholic drink and is particularly suitable for young consumers.

The invention discloses an extraction process of medicinal components of a Chinese herbal medicine safflower and particularly relates to an extraction process of carthamin yellow. The extraction process comprises the following steps: extraction of medicinal materials, adsorption by virtue of a macroporous adsorption resin column, primary elution, adsorption by virtue of a polyamide column, secondary elution, concentration and spray-drying. The extraction process of carthamin yellow can be used for effectively solving the disadvantages existing in the prior art of the background technology, the yield of the extracted carthamin yellow is not less than 2%, hydroxyl safflower flavin A contained in the carthamin yellow is not less than 20%, and general flavone contained in the carthamin yellow is not less than 80%.

The invention discloses a fruity lollypop and a processing technology. A formula is prepared from the following components in percentage by mass: 40 to 50 percent of white granulated sugar, 20 to 30 percent of water, 10 to 20 percent of glucose syrup, 1 to 1.5 percent of citric acid, 3 to 5 percent of tea polyphenol, 6 to 8 percent of fruit juice concentrate and 0.2 to 0.3 percent of natural pigment, wherein the natural pigment is one of carotene, monascus color, carthamin and gardenia blue. The processing technology comprises the following steps: step one, material selecting; step two, sugardissolving; step three, mixing; step four, boiling; step five, blending; step six, sprouting and forming. According to the fruity lollypop disclosed by the invention, the components of the fruity lollypop adopt fruit puree, the original flavor of fruits is fully reserved, and the fruity lollypop is harmless to a human body; the technology of the fruity lollypop is simple and strict, the fruity lollypop is suitable for batch production, and compared with a lollypop made of a common essence additive, differentiation competitive advantage is formed.

The invention discloses a method for testing the quality of tibetan medicine composition Liuwei Datuoyeyunshi preparation. The method comprises the following steps: carrying out the qualitative identification on the Datuoyeyunshi and Amomum kravanh in the Liuwei Datuoyeyunshi San by susing a thin layer chromatography (TLC method), and adopting a high performance liquid chromatography (HPLC method) to carry out the qualitative identification on the gallic acid contained in the Datuoyeyunshi and the pomegranate seed, the cinnamaldehyde contained in the cinnamon, the piperine contained in the fructus piperis longi and the hydroxyl carthamin yellow A contained in the safflower carthamus in the Liuwei Datuoyeyunshi San. The invention provides the method for identifying the Datuoyeyunshi and Amomum kravanh in the preparation, and a method for testing the contents of effective ingredients such as the gallic acid, the cinnamaldehyde, piperine, the hydroxyl carthamin yellow A and the like, the quality standard of a product is improved, the security, effectiveness and controllable quality of the medicine are ensured, and thus the preparation can be used for curing diseases more effectively.

The medicinal wine for preventing and treating cardiac and cerebral vascular diseases is prepared with notoginseng, schisandra, haw, wolfberry fruit, safflower and white spirit in 40-60 % alcohol content in certain weight proportion. The medicinal wine contains wintercherry red essence, safflower red essence, carthamin, hyperoside, rutin, betaine, polysaccharide, coarse fat, coarse protein, vitamins, trace elements, etc. It has the functions of tonifying heart, resisting myocardial ischemia and myocardial infaction, resisting anoxia, dredging blood vessel, improving micro circulation, etc. and thus may be used in preventing and treating cardiac and cerebral vascular diseases.

The invention relates to traditional Chinese medicine health scented tea capable of beautifying and losing weight. The traditional Chinese medicine health scented tea is obtained by combining the following components in percentage by weight: 8%-20% of rose polysaccharide, 5%-25% of carthamin yellow, 10%-30% of chrysanthemum general flavone, 15%-30% of hawthorn flavone, 10%-20% of betaxanthin and 10%-20% of campsis grandiflora apigenin. The traditional Chinese medicine health scented tea adopts simple and cheap medicines; the cost of the medicines for a formula is low; in the aspect of taking, the mouth feel is good; furthermore, the pure natural medicines are adopted, and no toxic additive or addiction medicines are added; the traditional Chinese medicine health scented tea does not inhibit appetite, does not cause diarrhea, has no toxic side effects and is not addicted; the traditional Chinese medicine health scented tea has the functions of enhancing the immunity of the organism, improving the micro-ecological environment of gastrointestinal tracts, and blocking the generation of free radicals and the like, and has the effects of enriching yin and nourishing kidney, enriching blood and beautifying, whitening, removing speckles, beautifying skins, and removing fat and losing weight. The traditional Chinese medicine health scented tea can be widely applied to the fields of traditional Chinese medicine health, beautifying and weight losing.

The invention relates to the field of bioscience technology; as main active ingredients of safflower, carthamin yellow A with hydroxyl has the content which directly influences on the quality of the safflower. The invention takes pure-line parent of the carthamin yellow A with hydroxyl and without hydroxyl and F<1>, F<2> generations generated by mating as the materials; in accordance with the presence of carthamin yellow A with hydroxyl in each plant, carthamin yellow A with hydroxyl presence two ponds are established by applying BAS method and cDNA-AFLP method is used to analyze the expression properties of the both; differential expression genes in bound up with the carthamin yellow A with hydroxyl are separated; correctness of property gene type and cDNA-AFLP method is verified via RT-PCR. The specificity DNA segment obtained by the invention includes the nucleotide sequence shown as SEQ ID NO: 1-3. The invention applies the specificity DNA segment to screening the safflower breed of the carthamin yellow A with hydroxyl in order to realize to provide good conditions for oriented adjustment and control of the high quality properties of safflower.

The invention relates to a method for promoting saffron growth and increasing crocin content by the application of rare earth element. It inoculates the saffron callus to the vegetable cell medium containing rare earth elements, cytomin and archusia, cultures for 15 to 30 days under 15DEG C-30DEG C, then again inoculates the callus to the vegetable cell medium containing rare earth elements, cytomin and archusia for culturing 15 to 30 days under 15DEG C-30DEG C. It can promote the saffron cell growth and obtain more saffron cell biomass in the same culturing time compared with the prior part. The crocin content is markedly increased and the crocin obtained does not easy to turn brown.

The invention relates to medicine and a preparation technology thereof, namely heat clearing and hematostatic Mongolian medicine and preparation technology thereof. The Mongolian medicine is characterized by being prepared from the following active ingredients in parts by weight: 1 to 2 parts of gardenoside, 1 to 2 parts of rutin, 1 to 2 parts of carthamin, 1 to 2 parts of beta-sitosterol, 1 to 2parts of rheum emodin, 1 to 2 parts of glycyrrhizic acid, 1 to 2 parts of kutkin, 1 to 2 parts of rubican, 1 to 2 parts of alkannin, 1 to 2 parts of shellac resin, 3 to 5 parts of calcium carbonate, 3to 5 parts of calcium phosphate, 3 to 5 parts of amino acid, 2 to 3 parts of cholic acid and 2 to 3 parts of calculus bovis. The Mongolian medicine has the beneficial effects of heat clearing, bloodcooling and hematostatic effects, obvious curative effects on hemorrhage syndromes of hematemesis, hemafecia, menorrhagia, traumatic bleeding, liver diseases and the like, low toxic and side effect, wide suitable crowd range, convenience in taking, convenience in digestion and absorption and quick effect; thus, the Mongolian medicine hopefully becomes typical medicine for treating lung diseases.

A pharmaceutical composition, including, parts by weight of: 100-170 of a ginkgo flavone, 40-100 of a jujube extract, 100-200 of an extract of a peel of Trichosanthes kirilowii, 30-60 of a saponin of Codonopsis, 50-100 of a saponin of American ginseng, 40-70 of a saponin of Radix astragalu, 20-50 of hirudin, 3-10 of a coenzyme Q10, 40-100 of a longan extract, 20-50 of a modified starch, 100-150 of a carthamin, 100-150 of an extract of peach kernel, 30-50 of a gastordin, 120-200 of a salvianolic acid, 40-90 of an extract of Ligusticum chuanxiong, 100-150 of a saponin of Panax notoginseng, 0-50 of a black sesamin, and 0-50 of an astaxanthin.

The invention relates to a medicinal composition for treating renal diseases and the pharmaceutical use of the medicinal composition. The composition contains rhein, physcion, emodin glucoside, chrysophanol glucoside, salvianic acid, salvianolic acid B, hydroxysafflor yellow A, astragaloside, astragalus polysaccharide, salvianolic acid A, calycosin-7-glucoside, physcion glucoside, rosmarinic acid, carthamin yellow A, salvianolic acid D, salvianolic acid H, protocatechuic aldehyde, caffeic acid and gallic acid, wherein the chrysophanol glucoside is chrysophanol monoglucoside, the emodin glucoside is emodin monoglucoside, and the physcion glucoside is physcion monoglucoside. The composition can also contain C11H9N6O4, C17H14O4, C21H20O9, C19H32O12, C30H36O15 and C30H44O15. The composition is a preparation in a solid form, a liquid form, a gas form or a semisolid form, and a great number of experiments show that the composition can be used for treating renal diseases, renal failure, nephrotic syndromes, cardiovascular and cerebrovascular diseases, neoplastic diseases and the like.

The invention belongs to the technical field of beverage processing and discloses a Liupao tea vinegar beverage and a preparation method thereof. The beverage is prepared from, by weight, 400-1100 parts of Liupao tea, 300-900 parts of cordate telosma, 90-200 parts of medicinal materials, 1-3 parts of stevioside, 2-6 parts of citric acid, 2-6 parts of ascorbic acid, 2-6 parts of carthamin yellow, 3-5 parts of nisin, 2-4 parts of carboxymethyl cellulose sodium, 2-4 parts of citronellal, 1-3 parts of disodium guanylate and 1000-2000 parts of water. The beverage is obtained by steps of extracting, mixing, sterilizing, filling, sealing, cooling and the like. Raw materials of the Liupao tea vinegar beverage are easy to acquire, the preparation method is simple, and short production cycle, low cost and long product storage time are realized. In addition, the Liupao tea vinegar beverage has the advantages of nutritional richness, sweet-sour tastiness, strong tea aroma and special flavor and is a novel nutritional tea vinegar beverage remarkably effective in fever treatment.

The invention provides a medicinal composition containing carthamus tinctorius yellow color, which comprises aceglutamide and carthamus tinctorius yellow color by a predetermined proportion, and can be used for preparing medicament for the treatment of cerebrovascular diseases, hepatic coma, hemiplegia, paralysis, memory obstacle, coronary disease and angiitis.

The invention provides a natural pigment composition. The natural pigment composition is prepared from emulgator, at least two of gardenia yellow pigment, curcumine, norbixin, carthamin yellow, citrus yellow pigment, xanthophyll and riboflavin, and at least one of purple sweet potato red pigment, mulberry red pigment, chestnut shell pigment and blueberry pigment. The uniform and stable natural pigment composition which is of different color systems and different hues can be obtained by mixing the natural pigment according to any ratio, and the defects of single pigment are overcome. Meanwhile, the pigment composition can be more stable due to the red pigment, a chelating agent and a pH regulating agent which are contained by the pigment composition. The invention further discloses a preparation method of the natural pigment composition. The method is simple and easy to operate.

The invention discloses a carthamin yellow sublingual tablet. The carthamin yellow sublingual tablet comprises, by weight, one part of carthamin yellow, 3-4 parts of filling agents and 1-2 parts of disintegrating agents. The filling agents are one or more of mannitol, sorbitol, xylose and lactose. The disintegrating agents are one or more of crosslinking povidone, cross-linked carboxymethyl starch and sodium carboxymethyl cellulose and sodium. The invention further discloses the preparation method of the carthamin yellow sublingual tablet and application in preparing medicines for curing ischemic brain injury. The carthamin yellow sublingual tablet has good disintegrating effect, can be absorbed quickly, has good taste and appearance, and provides a new way for clinical application of carthamin yellow.

The invention relates to a content determination method of Xuebijing intermediate multi-index components. The content determination method has the advantages that the method is good in precision, good in reproducibility, good in stability and capable of being used to detect the content of hydroxyl carthamin yellow A, paeoniflorin, ferulic acid and benzoic acid in Xuebijing injection intermediate, product quality can be increased favorably, and the life quality of people can be increased.

The invention discloses plant-dyed highly-filled degradable plastic. The plant-dyed highly-filled degradable plastic is prepared from, by weight, 25-80 parts of biodegradable materials, 30-75 parts of filling powder, 2-10 parts of auxiliaries and 5-10 parts of plant coloring agents; the plant coloring agents adopt one of curcumin, gardenia yellow, carthamin, quercitrin, munjistin, indigotin, gardenia blue, chlorophyll, capsanthin and logwood black, and the plant degradable materials comprise any one of poly butylenes succinate, polyethylene terephthalate and polylactic acid. The plant-colored highly-filled degradable plastic is easy to degrade, clear in color and suitable for being applied to production and manufacture of various plastic products.

The invention discloses a novel Shatian pomelo tea vinegar drink, which comprises the following raw materials: Shatian pomelo pulp, Shatian pomelo peel, golden camellia, nutmeg, dark plum, semen plantaginis, licorice, hovenia dulcis thumb, persimmon leaf, Chinese olive, semen lablab album, radix sophorae flavescentis, galangal, orange peel, amomum tsao-ko, grape vinegar, ginkgetin, potassium iodide, carboxymethylcellulose sodium, agar, polyvinyl sodium, sodium alginate, a DuPont EEA2112AC compatilizer, a food-grade antioxidant BHT, locust bean gum, carthamin yellow, nisin, trisodium glycyrrhizinate, glucose, fructose, Thaumatin, vitamin A, vitamin C, vitamin D, isoleucine, lysine, threonine, tryptophan, iron element, manganese element, chromium element, copper element, ethyl-furfuryl fumarate, potassium inosinate, potassium guanylate, sodium L-glutamate, 9-cycloheptadecanone, hydroxycitronellal, ionone and vanillin. The drink provided by the invention can effectively break down alcohol, thus relieving damage of alcohol to the nervous system, etc.

The invention relates to a medicinal composition for preventing and treating myocardial ischemia. The medicinal composition comprises the following raw materials in parts by weight: 250 parts of tanshinol, 20 parts of carthamin yellow, 80 parts of puerarin and 150 parts of glycyrrhizin. Through studies, an inventor discovers that the medicinal composition has an obvious prevention and treatment effect on the myocardial ischemia.

The invention relates to a medicine, in particular to a Mongolian medicine for treating rheumatoid arthritis and a preparation method of the Mongolian medicine. The Mongolian medicine is characterizedby being prepared from the following crude drugs in parts by weight: 4 to 8 parts of an ethanol extract of dianthus superbus, 2 to 4 parts of calcium sulfate, 1 to 2 parts of carthamin and 0.05 to 0.1 part of vitamin A. The preparation method comprises the following steps: crushing other crude drugs except the calcium sulfate, the carthamin and the vitamin A and passing through a sieve with 100 meshes; then uniformly mixing a crushed substance with the calcium sulfate, the carthamin and the vitamin A to obtain watered pills, or tablets, or dropping pills, or a powder. The invention has the beneficial effects that the Mongolian medicine which has the advantages of obvious curative effect on the rheumatoid arthritis, stable effect, low possibility of relapse, simple preparation and low price and the preparation method of the Mongolian medicine are provided. Resources are saved, promotion and use are facilitated, the mongolian medicine is expected to become a priority drug for patients with the rheumatoid arthritis and brings gospel to the patients with the rheumatoid arthritis.

The invention discloses a method for extracting carthamin yellow from safflowers. The method comprises the steps that a gas bag juicer is used for juicing fresh safflowers and performing solid-liquid separation, residues obtained after solid-liquid separation is subjected to water extraction, and the water extraction solution is refined. According to the step of refining the water extraction solution, primary filtering, resin adsorption and eluent centrifuging, primary reverse osmosis concentration and secondary reverse osmosis concentration are included, and therefore the high-content carthamin yellow is obtained. According to the method for extracting carthamin yellow, the water consumption and energy consumption of the carthamin yellow extraction process are lowered, the carthamin yellow extraction rate reaches up to 96% or above, and the production cost of the carthamin yellow is greatly lowered.