294 results about "Coma" patented technology

The invention provides applications of levorotary oxiracetam and oxiracetam in preparing drugs for preventing or treating coma. Experimental results indicate that levorotary oxiracetam has obvious awaking effect on coma caused by alcoholism, but dextrorotary oxiracetam basically has no effect, and the awaking effect of levorotary oxiracetam is two times of that of dextrorotary / levorotary mixed oxiracetam; levorotary oxiracetam has remarkable awaking effect on comas caused by both trauma and anesthesia.

An improved ophthalmic instrument including an integral wavefront sensor and display device, wherein the wavefront sensor measures phase aberrations in reflections directed thereto to characterize aberrations of the eye and is operably coupled to the display device, which displays a graphical representation of the aberrations of the eye. Such graphical representation may include: two dimensional contour maps that graphically depict contribution of pre-specified terms (such as spherical aberration, astigmatism and coma) for the aberrations of the eye, coefficients corresponding to such pre-specified terms that characterize the aberrations of the eye, or predefined two-dimensional icons that provide a general graphical depiction of such prespecified terms. Such graphical representations provide the practitioner with valuable information characterizing the high order optical errors of the eye (which is far beyond the diopter information typically provided by current ophthalmic instruments) for use in diagnosis and treatment of abnormalities and disease in the eye.

An method for analyzing irreversible apneic coma (IAC) for determining the presence of irreversible apneic coma (IAC) by analyzing the heart rate variability of a brain traumatic patient, thereby providing a physician a reference index to determine whether brain death has occurred. This method includes, at first, recording an electrocardiogram (ECG) from a subject. Then, analyzing R-R interval in said electrocardiogram (ECG), and plotting said R-R interval into Poincaré plot, wherein the X coordinate in said Poincaré plot represents R-R interval(n), and n is a 1˜data number. Y coordinate in said Poincaré plot represents RR(n+1). And, finally, quantifying said Poincaré plot, and obtaining semi-major axis (SD1), semi-minor axis (SD2), and SD1 / SD2 of said Poincaré plot, as well as Poincaré plot area.

An improved method for treating the eye includes the step of providing an ophthalmic instrument including an integral wavefront sensor. The wavefront sensor measures phase aberrations in reflections directed thereto to characterize aberrations of the eye. The wavefront sensor may be operably coupled to a display device, which displays a graphical representation of the aberrations of the eye. Such graphical representation may include: two dimensional contour maps that graphically depict contribution of pre-specified terms (such as spherical aberration, astigmatism and coma) for the aberrations of the eye, coefficients corresponding to such pre-specified terms that characterize the aberrations of the eye, or predefined two-dimensional icons that provide a general graphical depiction of such pre-specified terms. Such graphical representations provide the practitioner with valuable information characterizing the high order optical errors of the eye (which is far beyond the diopter information typically provided by current ophthalmic instruments) for use in diagnosis and treatment of abnormalities and disease in the eye. In addition, the wavefront sensor may be part of an adaptive optical subsystem that compensates for the phase aberrations measured therein to provide phase-aligned images of the eye for capture by an image capture subsystem. Such images may be used by practitioner in diagnosis and treatment of abnormalities and disease in the eye.

An intraocular lens comprises optical part configured to be implanted in an eye of a subject. The intraocular lens further comprises at least one aspheric surface configured, in combination with a lens in the capsular bag of an eye, to reduce an aberration of a wavefront passing the eye. The aberrations may include astigmatism, coma, and / or spherical aberrations. An aberration of the intraocular lens may be expressed as a linear combination of Zernike polynomial terms that may include a Zernike coefficient a11. The Zernike coefficient a11 may be selected to reduce a spherical aberration of a wavefront passing the eye and / or to compensate for an average value resulting from a predetermined number of estimations of the Zernike coefficient a11 in a population of corneas and capsular bag lenses.

Embodiments of the present invention combine static analysis, source code instrumentation and feedback-guided fuzz testing to automatically detect resource exhaustion denial of service attacks in software and generate inputs of coma for vulnerable code segments. The static analysis of the code highlights portions that are potentially vulnerable, such as loops and recursions whose exit conditions are dependent on user input. The code segments are dynamically instrumented to provide a feedback value at the end of each execution. Evolutionary techniques are then employed to search among the possible inputs to find inputs that maximize the feedback score.

Described are methods, devices, and systems for a novel, inexpensive, easy to use therapy for treatment of coma, post-traumatic stress disorder, Parkinson's disease, cognitive performance, and / or amblyopia. Described are methods and devices to treat coma, post-traumatic stress disorder, Parkinson's disease, cognitive performance, and / or amblyopia that involves no medication. Methods and devices described herein use alternating magnetic fields to gently “tune” the brain and affect symptoms of coma, post-traumatic stress disorder, Parkinson's disease, cognitive performance, and / or amblyopia.

A disposable lens for reconfiguring the cornea of an eye for ophthalmic laser surgery includes a lens which has a flat anterior surface that is formed opposite a contact surface. A skirt surrounds the contact surface and extends outwardly therefrom to define a chamber. The skirt is formed with a groove which creates a suction channel between the skirt and the contact surface in the chamber. In its operation, the lens is positioned over the cornea and a vacuum pump is selectively activated to create a partial vacuum in the suction channel. Due to this partial vacuum, the cornea is drawn into the chamber where it is urged against the contact surface of the lens. The result of this is that the cornea is flattened into a configuration where the introduction of spherical aberration and coma into a light beam passing into the cornea is reduced or eliminated.

An improved ophthalmic instrument including an integral wavefront sensor and display device, wherein the wavefront sensor measures phase aberrations in reflections directed thereto to characterize aberrations of the eye and is operably coupled to the display device, which displays a graphical representation of the aberrations of the eye. Such graphical representation may include: two dimensional contour maps that graphically depict contribution of pre-specified terms (such as spherical aberration, astigmatism and coma) for the aberrations of the eye, coefficients corresponding to such pre-specified terms that characterize the aberrations of the eye, or predefined two-dimensional icons that provide a general graphical depiction of such prespecified terms. Such graphical representations provide the practitioner with valuable information characterizing the high order optical errors of the eye (which is far beyond the diopter information typically provided by current ophthalmic instruments) for use in diagnosis and treatment of abnormalities and disease in the eye.

Intraocular lenses (IOLs) and related methods. One embodiment provides an IOL which includes a lens optic and a pair of haptics. The haptics can be coupled to the lens optic and can cause compression of the lens optic when the IOL is fixated in an eye. The lens optic can have a compressed geometry, an uncompressed geometry including an aberration, and a desired geometry. The compressed geometry can be the desired geometry. The aberration can be astigmatism, coma, or spherical aberration. For instance, the aberration can be astigmatism of about 0.17 D at the spectacle plane and of about 0.25 D at the intraocular lens plane. Moreover, the haptics can define a first axis between the haptics; the lens optic can define a second axis perpendicular to the first axis; and the uncompressed geometry can differ from the compressed geometry in the vicinity of the second axis.

Disclosed are methods and systems and methods for neuromodulation of the Reticular Activating System using ultrasound to produce acute effects or Long-Term Potentiation (LTP) or Long-Term Depression (LTD). Included is control of direction of the energy emission, intensity, pulse duration, frequency, and phase / intensity relationships to targeting and accomplishing up-regulation and / or down-regulation. The invention can be applied for a variety of clinical purposes such as reversibly putting a patient to sleep or waking them up (for example, for the purpose of anesthesia) or reversibly putting a patient into a coma (for example for the purpose of protecting or rehabilitating the brain of the patient after a stroke or head injury).

The present invention relates generally to a diagnostic device including a prognostic assay for parameters which are indicative of a condition or event associated with the systemic vasculature. More particularly, the present invention provides an assay to detect parameters associated with a vascular disease including cardiovascular, stroke, pulmonary, renovascular, cerebrovascular, thrombotic or generalized arterial or venous condition or event including acute coronary syndrome such as but not limited to acute myocardial infarction, heart failure, atheromoma or a thrombotic condition. The identification of these parameters or more particularly a pattern of parameters enables the diagnosis of a condition or event or the determination of the risk of development of a condition or event associated to the systemic vasculature. Still more particularly, the present invention is directed to a diagnostic device comprising a set of members wherein one or more of said members has or have specific or generic binding partners in a biological sample from an animal including human subject wherein the pattern of binding of the members to the binding partners is indicative, predictive or otherwise associated with a likelihood of a condition or event within the systemic vasculature. The absence of detection of specific or generic binding partners is also of indicative or predictive value. This is particularly important in cases where patients are unable to communicate advice to a physician on their own condition, such as during surgery or for patients in a coma. It is also useful in determining the risk of a vascular disease including cardiovascular, stroke, pulmonary, renovascular, cerebrovascular, thrombotic or generalized arterial or venous conditions or events in a healthy subject or a subject entering into an exposure to risk such as surgery or chemotherapy. The present invention is useful inter alia for the identification and / or quantitation of biochemical markers of conditions or events in the systemic vasculature such as heart disease, heart disorders, infections of the heart, stroke and thrombosis as well as the determination of a risk of development of these conditions including the absence of disorders or absence of risk of the development of a disorder. The assessment of such conditions may be made in a clinical setting, as part of triage, as part of a routine testing protocol and / or as a laboratory procedure.

A method of identifying a site of injury in a pediatric patient with brain injury is provided which comprises obtaining an electroencephalogram signal on the patient. The identification of phase synchrony within the signal is indicative of the site of brain injury. Electroencephalogram signals may also be used to determine prognosis of a pediatric patient in a coma in which an increase in the temporal variability of phase synchronized EEG signals over time is indicative of an improvement in the patient.

Provided is an optical information recording and reproducing apparatus including a light beam expander for correcting spherical aberration caused when a plurality of recording layers of an optical disc are brought into focus by changing a divergent angle or a convergent angle of light entering an objective lens, and coma aberration correcting means for correcting coma aberration caused by tilt of the optical disc. When the coma aberration correcting means is driven, the value of a drive signal is varied according to a target recording layer of the optical disc. As a result, even when a transmission layer thickness varies in a multilayer recording medium, coma aberration does not remain in any of the recording layers.

The invention discloses a novel traditional Chinese medicine composite for treating coma and heart syncope symptoms and a preparation method thereof. The traditional Chinese medicine composite mainly comprises the following raw material medicines: styrax, benzoin, holy basil, rhizoma acori graminei, toad venom, tambac, santalwood, rosa banksiae, nutgrass flatsedge, toosendan fruit, radix aristolochiae, common fibraurea, macrostem onion, fructus citri sarcodactylis, citron, aspongopus, lotus node, madder, dalbergia wood, plant soot, rhizoma ligustici wallichii, corydalis tuber, turmeric, curcuma, mastic, myrrh, radix salviae miltiorrhizae, peach kernel, safflower, radix notoginseng, ground beetle, stiff silkworm, logwood, draconis sanguis, catechu, rhizoma sparganii, rhizoma zedoariae, pangolin scales, spatholobus stem, motherwort, angelica, rhizoma atractylodis, radix puerariae, angelica root, sibirian button bur, magnolia flower, purple common perilla, chrysanthemum, baikal skullcap root and coptis root. The traditional Chinese medicine composite can be prepared into any common oral preparation according to a conventional traditional Chinese medicine preparation method. The invention can obviously improve diseases which are caused by the inverse disorder of the functional activities of qi, fluctuation warp and non-smooth qi of yin and yang and represent coma, delirium, exanimation and asphyxia as main symptoms or are accompanied with the symptoms of asphyxia and coldness of limbs, dottiness and the like, and has definite clinical curative effect, obvious curative effect and quick acting. Because the traditional Chinese medicine composite basically adopts medicine-food homologous medicines specified by the national dispensatory for combination, the traditional Chinese medicine composite has the advantages of low expense, no toxic or side effect basically and the like.

The invention relates to an alarming method for detecting fall over of a human body. The alarming method is implemented by an intelligent mobile phone and a wearing type watch. When an acceleration sensor in the intelligent mobile phone detects an acceleration meeting a fall over feature, the acceleration is compared with an acceleration value detected by the wearing type watch; if the error is not greater than 10 percent, a fall over accident may be happened; when a height sensor detects that a height change value is greater than a set threshold value, the human body has fallen over; when the wearing type watch detects that an acceleration value obtained after the human body falls over is lower than the set acceleration threshold value, the human body is in a coma state or arms of the human body cannot move; when the height change value detected by the height sensor is greater than a height change threshold value, after a period of time, if the height is still not recovered to a normal value and the detected acceleration value is lower than the acceleration threshold value, a fall over alarm is given. The alarming method disclosed by the invention is convenient to operate and low in false alarm rate and is suitable for the technical field of dangerous alarming.

The invention relates to the determination of higher-order aberrations of an optical element over an optical zone that is larger than the typically limited measured zone over which the aberrations are measured. This is accomplished by apparatus, systems, and methods in which, preferably, the Zernike data from an aberration measurement is fit to a conic function. The conic function smoothly and continuously increases or decreases between the measured zone and the optical zone allowing the extrapolated data to accurately determine the aberrations over the optical zone. According to the invention, a plurality of independent conic plus piston sections that vary azimuthally can very accurately describe a wavefront aberration composed of defocus, astigmatism, spherical aberration, secondary astigmatism, and tetrafoil. The description of primary coma and trefoil will not be as good because they vary with the 3<rd >order of the radial component. However, the description error is relatively small. A tilt term can be added to account for the tilt component of the coma and trefoil terms.

This application describes a kit of contact lenses comprising two or more contact lenses having a known higher order aberration for each given lens power. By way of example, the higher order aberration may comprise a spherical aberration, a coma aberration, or a trefoil aberration. A practitioner selects a lens from the kit and applies the lens to a patient's eye and measures a residual higher order aberration of the lens-eye system. In cases where the residual higher order aberration exceeds a predetermined magnitude, the practitioner selects a second lens from the kit, applies the second lens to the patient's eye and measures the residual higher order aberration of the lens-eye system.

The invention discloses an assessment method of auxiliary CRS-R scale auditory shock based on a brain-computer interface. The assessment method comprises following steps of: 1) selecting simulation, arranging and designing an experimental paradigm; 2), collecting signals; 3) performing data processing; 4) counting inspecting evaluation standards. The assessment method of auxiliary CRS-R scale auditory shock based on the brain-computer interface has following beneficial effects: based on an auditory extraneous experimental paradigm, mismatch negative waves MMN and P300, peculiar to human race, are induced; in combination with an auditory shock assessment method of a coma recovery scale CRS-R, scores of CRS-R auditory shock items are accessed by adoption of the brain-computer interface and a peak detection algorithm; and therefore, the method can not only be effectively used for assessment diagnoses of the coma recovery scale, tracking of recovery effect and selections of a prognosis treatment scheme but also provide scientific and objective detection data to the conventional scale diagnoses in order to ensure authenticity and effectiveness of detection results..

The invention provides a lower jaw supporter, which solves the problem that can not be solved in the prior art; the problem is upper airway obstruction (snoring) of non-trachea cannula general anesthesia patients and unconscious patients including patients of coma, alcoholic intoxication, toxicosis and the like. The technique proposal is that the lower jaw supporter comprises a tie plate and movable supports which are arranged at the left and the right sides of the tie plate; and the upper end of the movable support is provided with a lower jaw angle fixed disk which is adaptive to the shape of lower jaw angle. The left and right positions and the height of the movable support can be adjusted. The lower jaw supporter completely relieves hands of anaesthetists or nurses who need to use hands to support lower jaws for a long time, and provides a device specially used for supporting the lower jaw loose of general anesthesia non-trachea cannula patients; and the device mainly prevents or avoids the upper airway obstruction of the patients caused by the wallowing of tongues so as to disarm the risks of chronic oxygen deficiency of body and accumulation of carbon dioxygen caused by that the upper airways of the patients are blocked or stopped.

The present invention provides a kit of contact lenses, comprising two or more contact lenses having a known higher order aberration for each given lens power. By way of example, the higher order aberration may comprise a spherical aberration, a coma aberration, or a trefoil aberration. A practitioner selects a lens from the kit and applies the lens to a patient's eye and measures a residual higher order aberration of the lens-eye system. In cases where the residual higher order aberration exceeds a predetermined magnitude, the practitioner selects a second lens from the kit, applies the second lens to the patient's eye and measures the residual higher order aberration of the lens-eye system.

There is provided an optical system including: a first lens having positive refractive power; a second lens having positive refractive power; a third lens having refractive power and having a convex object-side surface; a fourth lens having refractive power; and a fifth lens having refractive power, wherein the first to fifth lenses are sequentially disposed from an object side, whereby spherical aberration and coma aberration may be improved to realize high resolution in images captured thereby and increase an amount of light incident through the lenses to an image sensor.

The invention provides a method and device for evaluating the coma degree. The method comprises: electroencephalogram data of a patient is acquired; the electroencephalogram data is pretreated, and purified electroencephalogram signals are obtained; according to the purified electroencephalogram signals, the coma degree of the patient is evaluated. According to the method, the coma degree of the patient is automatically evaluated according to the purified electroencephalogram signals of the coma patient, manual intervention in the evaluating process of the coma degree is lowered, the influence of subjective factors of medical personnel on the evaluating process is avoided, man-made erroneous judgment is avoided, the evaluating error is reduced, and the evaluating accuracy is improved. Sample entropy is applied to evaluation of the coma degree, the sample entropy corresponding to the purified electroencephalogram signals is calculated, according to a threshold value range of the sample entropy, the coma degree is evaluated, quantification evaluation of the coma degree is achieved, and the evaluation efficiency is greatly improved. Meanwhile, according to the purified electroencephalogram signals, prognosis judgment is automatically conducted, the sample entropy is applied to the prognosis judgment of the coma patient, and the efficiency and accuracy of the prognosis judgment are improved.

The invention concretely relates to an induced scleroderma guani breeding method, wherein the problems that when the conventional scleroderma guani breeds, the obtainment of substitute hosts is limited by time and the heavy demand of the scleroderma guani on production cannot be satisfied because of limited sources are solved. The induced scleroderma guani breeding method comprises the following steps of: a, buying breeding scleroderma guani and preserving at low temperature; b, buying inducing hosts and preserving at low temperature; c, buying the substitute hosts and carrying out chemical coma and then processing at low temperature, wherein the substitute hosts are first hatched pupae of barley pests; d, inoculating the scleroderma guani on the inducing hosts to carry out induced spawning; e, putting the substitute hosts and culturing; and f, storing at low temperature and transporting. By means of the induced scleroderma guani breeding method provided by the invention, the problems that when the conventional scleroderma guani breeds, the obtainment of the substitute hosts is limited by time and the heavy demand of the scleroderma guani on production cannot be satisfied because of the limited sources are solved; the breeding yield of the scleroderma guani can be greatly increased through the method of culturing the scleroderma guani by utilizing the substitute hosts after the induced spawning by utilizing the inducing hosts; and in the meantime, the influences of cost and time limits when the substitute hosts are selected are reduced.

The invention discloses a minitype microcirculation imaging monitoring device which comprises a light source module, a surface reflection filtering module, a reflection imaging module and an image receiving device. The reflection imaging module comprises at least one reflector with focal power. The light source module provides illuminating light. The surface reflection filtering module is used for adjusting the strength distribution of the illuminating light and projecting the light to a tissue surface. The reflection imaging module is used for collecting light which is scattered backwards in tissue and returns to the surface of skin, and the light is reflected for multiple times through the reflector to be gathered and then imaged to the image receiving device. The minitype microcirculation imaging monitoring device is simple in size and can be placed in the mouth of a patient or other parts with limited sizes, so that stable and long-time microcirculation monitoring can be achieved. Moreover, in addition to general patients, microcirculation monitoring can also be conducted on patients who are in coma or shock or can not cooperate with doctors to make corresponding response easily. The invention further discloses a microcirculation imaging monitoring method.

The invention discloses a primotest clustered hair single cell bacterium (Comamonas testosteroni) WXZ-18 CGMCC No.1800 strain with aerobic denitrifying property and a method to denitrify the waste water; which is characterized by the following: possessing strong tolerance degree for dissolved oxygen; deacidizing nitrate and nitrite with distinctive speed under the condition of 10-98% saturated dissolved oxygen; seeding to active sludge; proceeding enriched culture; realizing the aerobic anti-nitration.

The invention relates to a method acquiring telescope primary and secondary mirror alignment error based on astigmatism decomposition. The method includes the steps of measuring four misalignment rates of a secondary mirror and the proportionality coefficient of exit pupil wavefront error astigmatism coefficient to coma coefficient, wherein the proportionality coefficient is expressed through a zernike polynomial, measuring a real-time exit pupil wavefront error, placing a misalignment rate dx and a misalignment ty of the secondary mirror in one group, placing a misalignment rate dy and a misalignment rate tx of the secondary mirror in one group, decomposing a astigmatism item Ast into Astx and Asty, constructing a relation model of the misalignment rates and the astigmatism item, solving a coupling coefficient Alpha x and a coupling coefficient Alpha y, constructing a relation model of the misalignment rates and a coma item, and solving the misalignment rates of the secondary mirror according to a constructed relation model of the misalignment rates and the wavefront error.