1251results about How to "Increase variability" patented technology

A method, system, and computer program product related to the maintenance of optimal control of diabetes, and is directed to predicting patterns of hypoglycemia, hyperglycemia, increased glucose variability, and insufficient or excessive testing for the upcoming period of time, based on blood glucose readings collected by a self-monitoring blood glucose device. The method, system, and computer program product pertain directly to the enhancement of existing home blood glucose monitoring devices, by introducing an intelligent data interpretation component capable of predicting and alerting the user to periods of increased risk for hyperglycemia, hypoglycemia, increased glucose variability, and ineffective testing, and to the enhancement of emerging self-monitoring blood glucose devices by the same features. With these predictions the diabetic can take steps to prevent the adverse consequences associated with hyperglycemia, hypoglycemia, and increased glucose variability.

Apparatus is provided for treating a condition of a subject, including an electrode device, adapted to be coupled to an autonomic nerve of the subject, and a control unit. The control unit is adapted to drive the electrode device to apply to the nerve a stimulating current, which is capable of inducing action potentials in a therapeutic direction in a first set and a second set of nerve fibers of the nerve, and to drive the electrode device to apply to the nerve an inhibiting current, which is capable of inhibiting the induced action potentials traveling in the therapeutic direction in the second set of nerve fibers, the nerve fibers in the second set having generally larger diameters than the nerve fibers in the first set. Other embodiments are also described.

Manufacturing method of grinding surface on glass cosmetics, in particular the nail and skin file, from flat glass of FLOAT type, is carried out by marking at least one abrasive surface on one or two sides of a glass pane or intermediate product. This surface is then coated with fusing glue, powdered with clean quartz sand with grain size between 1 and 500 μm using a sieve, and the surplus sand is knocked-down. The intermediate product with fixed sand is inserted into the fusing furnace where it is baked at the temperature of up to 900° C. The abrasive surface may be roughened by sand blasting before the fusing glue application; the intermediate product coated with fusing glue can be decorated with glass fritte.

A method for providing a custom shoe to a consumer, including identifying at least one characteristic about a consumer that is present within the retail store, the at least one characteristic relating to the consumer's foot. Also included is selecting a plurality of pre-fabricated footwear components based on the at least one characteristic, assembling the plurality of prefabricated footwear components into a custom shoe that is customized to the consumer, and presenting the custom shoe to the consumer before the customer leaves the retail store.

A method and on-chip controller for enhancing semiconductor chip process variability and lifetime reliability through a three-dimensional (3D) integration applied to electronic packaging. Also provided is an on-chip reliability / variability controller arrangement for implementing the inventive method.

A system for providing a shoe customized to a person includes a plurality of shoe cavity units each having an upper portion and a sole assembly coupled to the upper portion to form a shoe cavity configured to accommodate a foot. Also included is a plurality of interchangeable first shoe components each configured to be coupled to a shoe cavity unit and each configured to provide substantially the same first footwear function but having a different physical attribute based on differences among wearers, and a plurality of interchangeable second shoe components each configured to be coupled to a shoe cavity unit and each configured to provide substantially the same second footwear function but having a different physical attribute based on differences among wearers. A selected shoe cavity unit, a selected first shoe component and a selected second shoe component can be selected from their respective pluralities based on a characteristic of the person such that a combination of these selected items can be coupled to each other to provide a shoe customized to the person.

A method, system, and computer program product used for creating a custom footwear product. The method on which the system, and computer program product are based includes inputting in a retail store information about a characteristic of a consumer that relates to the consumer's foot, and receiving in the retail store a determination of a plurality of selected pre fabricated footwear components that have been selected based the information. Also included in the method is creating in the retail store a kit of prefabricated footwear components for the customer including the identified prefabricated footwear components to be assembled into the custom footwear product.

Apparatus is provided that includes an electrode device, adapted to be coupled to a vagus nerve of a subject, and a control unit, adapted to drive the electrode device to apply to the vagus nerve a current that reduces heart rate variability of the subject. Also provided is a method comprising applying to a vagus nerve of a subject a current that reduces heart rate variability of the subject.

A system and method for organization and analysis of complex and dynamically interactive time series is disclosed. One example comprises a processor based system for relational analysis of physiologic signals for providing early recognition of catastrophic and pathologic events such as pathophysiologic divergence. The processor is programmed to identify pathophysiologic divergence of at least one of first and second physiologic parameters in relationship to the other and to output an indication of the divergence. An object-based method of iterative relational processing waveform fragments in the time domain is described wherein each more complex waveform object inherits the characteristics of the waveform objects from which it is derived. The first physiologic parameter can be the amplitude and frequency of the variation in chest wall impedance or nasal pressure and the second parameter can be a measure or indication of the arterial oxygen saturation.

A loop is formed by a bow having across one side a strip or blade. The bow has flexure and memory. The flexure and memory of the bow are imparted to the strip, enabling the strip to be either taut or loose, depending on the pressure exerted by the operator upon the bow. The bow is held and manipulated by the operator with the thumb and finger. The strip is positioned under tension. A holder for the device allows additional variability in the angle of attack of the strip, and facilitates quick and easy interchange of the strips. A holder avoids insertion of fingers far back in the mouth, where working space is limited.

In one aspect, a method of enhancing semiconductor chip process variability and lifetime reliability through a three-dimensional (3D) integration applied to electronic packaging is disclosed. Also provided is an arrangement for implementing the inventive method. In another aspect, a method and on-chip controller are disclosed for enhancing semiconductor chip process variability and lifetime reliability through a three-dimensional (3D) integration applied to electronic packaging. Also provided is an on-chip reliability / variability controller arrangement for implementing the inventive method. In yet another aspect, base semiconductor chips, each comprising a plurality of chiplets, are manufactured and tested. For a base semiconductor chip having at least one non-functional chiplet, at least one repair semiconductor chiplet chiplet is vertically stacked. A functional multi-chip assembly is formed, which provides the same functionality as a base semiconductor chip in which all chiplets are functional.

Aspects of the invention relates to methods and compositions that are useful to reduce bias and increase the reproducibility of multiplex analysis of genetic loci. In some configurations, predetermined preparative steps and / or nucleic acid sequence analysis techniques are used in multiplex analyses for a plurality of genetic loci in a plurality of samples.

An implantable device for providing electrical stimulation of cervical vagus nerves for treatment of chronic cardiac dysfunction with leadless heart rate monitoring is provided. A stimulation therapy lead includes helical electrodes configured to conform to an outer diameter of a cervical vagus nerve sheath, and a set of connector pins electrically connected to the helical electrodes. A neurostimulator includes an electrical receptacle into which the connector pins are securely and electrically coupled. The neurostimulator also includes a pulse generator configured to therapeutically stimulate the vagus nerve through the helical electrodes in alternating cycles of stimuli application and stimuli inhibition that are tuned to both efferently activate the heart's intrinsic nervous system and afferently activate the patient's central reflexes by triggering bi-directional action potentials. Finally, the neurostimulator includes an integrated leadless heart rate sensor configured to sense heart rate and to record the sensed heart rate as data into a memory.

Disclosed herein are methods, systems, and apparatus for treating a medical condition of a patient, involving detecting a physiological cycle or cycles of the patient and applying an electrical signal to a portion of the patient's vagus nerve through an electrode at a selected point in the physiological cycle(s). The physiological cycle can be the cardiac and / or respiratory cycle. The selected point can be a point in the cardiac cycle correlated with increased afferent conduction on the vagus nerve, such as a point from about 10 msec to about 800 msec after an R-wave of the patient's ECG, optionally during inspiration by the patient. The selected point can be a point in the cardiac cycle when said applying increases heart rate variability, such as a point from about 10 msec to about 800 msec after an R-wave of the patient's ECG, optionally during expiration by the patient.

The present invention is directed toward a method for calibrating a biometric authentication device over time. The method of the present invention involves obtaining an authenticating biometric value from a biometric measurement. The biometric value is then weighted and integrated into the authentication data set or template.

A method for fabricating a transistor configuration including at least one trench transistor cell has a gate electrode and a field electrode disposed in a trench below the gate electrode. The trenches are formed in a semiconductor substrate. A drift zone, a channel zone, and a source zone are in each case provided in the semiconductor substrate. According to the invention, the source zone and / or the channel zone are formed at the earliest after the introduction of the trenches into the semiconductor substrate by implantation and diffusion.

The present invention provides a system for improving diastolic function of the heart comprising elastic elements and attachment elements, wherein said elastic elements and said attachment elements are configured such that they are capable of being interconnected to form a chain formed of an alternating series of said elastic elements and said attachment elements, and wherein said attachment elements are adapted to be anchored in the wall of the heart and with option for drug delivery to the wall of the heart. The invention further provides devices, methods and kits, for mounting the ventricular function assisting device of the invention.

Self-programmable thermostat control system and method that automatically senses, creates and suggests highly energy efficient optimized setback schedules in a controllable and predictable manner for a user in accordance with consistently updated historical occupancy patterns of a heated and / or cooled space. Through the use of this system and method, users will be able to reduce inefficiency from the setback schedules produced by other thermostats and select one of the many energy efficient setback schedules produced by the system through an easy to use display screen built into the self-programmable thermostat. With this unique system and method, the user is able to customize their energy efficiency and comfort level in their cooled and / or heated space by selecting the set-back schedule that fits best with their pocketbook and comfort level all at the turn of a knob.

An improved gate lock provides for easy engagement and allows for a high degree of variability of the orientation and position of the mating portions of the lock. The lock includes a lock pin movably retained in a base. The pin coordinates with, and engages, a latch in a separate receiver to provide a physical lock. The latch is spring-mounted in a locked position to allow it to slide laterally within the receiver to receive and capture the pin during the locking function. The receiver includes a pin slot or opening having an angled surface for directing the pin into the latch for easier movement and engagement. The latch has an angled or curved strike surface on which the pin slides during locking. A solenoid is mounted to the receiver and is connected to the latch to provide for automatic withdrawal of the latch for unlocking functions.

Vinyl addition polymer compositions, methods for forming such compositions, methods for using such compositions to form microelectronic and optoelectronic devices are provided. The vinyl addition polymer encompassed by such compositions has a polymer backbone having two or more distinct types of repeat units derived from norbornene-type monomers independently selected from monomers of Formula I: wherein each of X, m, R1, R2, R3, and R4 is as defined herein and wherein a first type of repeat unit is derived from a glycidyl ether substituted norbornene monomer and a second type of repeat unit is derived from an aralkyl substituted norbornene monomer.

A light module of a motor vehicle generates a spot distribution of a high-beam-light distribution formed by superimposition of the spot distribution and a base distribution generated by at least one other module. The light module comprises a plurality of separately controllable sub-modules that generate a plurality of stripe-shaped segments of the spot distribution that supplement it. Also, a headlight generates the high-beam-light distribution and comprises the light module. Furthermore, a headlight system comprises a pair of the headlights disposed in a front region toward sides of the vehicle and each of which generates the high-beam-light distribution. The headlights include corresponding light modules that generate stripe-shaped segments of left and right sides, respectively, of the spot distribution such that the stripe-shaped segments of the light modules of the headlights supplement the spot distribution or are at least partially superimposed thereon.

To perform link adaptation at radio interfaces of an enhanced packet data cellular network the system behavior is simulated for different C / I conditions. Two sets of tables are obtained, each table including upgrade and downgrade thresholds expressed in terms of Block Error Rate (BLER). The tables are specialized for taking into account EGPRS type II hybrid ARQ, Incremental Redundancy (IR). Transmitted blocks are checked for FEC and results are sent to the network that continuously updates BLER. A reliability filter output is used to decide the weight between new and old measurements. IR efficiency is tested for each incoming block and an indicative variable IR_status is filtered. Each threshold of BLER to be used is obtained by linear interpolation between the tabulated threshold without IR and with perfect IR, both weighed with filtered IR_status. Filtered BLER is compared with interpolated thresholds for testing the incoming of a MCS switching condition.

Synthesized body images are generated for a machine learning algorithm of a body joint tracking system. Frames from motion capture sequences are retargeted to several different body types, to leverage the motion capture sequences. To avoid providing redundant or similar frames to the machine learning algorithm, and to provide a compact yet highly variegated set of images, dissimilar frames can be identified using a similarity metric. The similarity metric is used to locate frames which are sufficiently distinct, according to a threshold distance. For realism, noise is added to the depth images based on noise sources which a real world depth camera would often experience. Other random variations can be introduced as well. For example, a degree of randomness can be added to retargeting. For each frame, the depth image and a corresponding classification image, with labeled body parts, are provided. 3-D scene elements can also be provided.

Systems and methods for employing histological and physiological biometric markers that are substantially unique to an individual in order to activate a device, participate in a transaction, or identify himself or herself, wherein at least one biometric marker is obtained by one or more electrical contacts on the surface of the skin. A biometric identification of an individual is obtained by a heartbeat waveform, which is acquired by one or more direct electrical contacts. A mechanism for biometric authentication is used that includes one or more electrodes, an electrical signal receiver, a memory module, and a processing module.

The present invention relates to a recombinant binding protein comprising at least one derivative of the Src homology 3 domain (SH3) of the FYN kinase, wherein at least one amino acid in or positioned up to two amino acids adjacent to the src loop and / or at least one amino acid in or positioned up to two amino acids adjacent to the RT loop is substituted, deleted or added. Furthermore, the invention is directed to fusion proteins comprising a binding protein according to the invention fused to a pharmaceutically and / or diagnostically active component. In addition, the invention concerns nucleotides coding for these binding and / or fusion proteins as well as corresponding vectors and host cells. Last but not least, the present invention relates to the use of binding and / or fusion proteins of the present invention for preparing a medicament or a diagnostic means as well as to pharmaceutical or diagnostic compositions comprising said binding and / or fusion proteins.

A method of generating pulsed coherent radiation, comprises the step of generating high harmonic pulses by an interaction of laser light pulses with a non-linear medium contained in a resonant cavity, wherein the non-linear medium is arranged in an environment of reduced pressure. Furthermore, a radiation source of generating pulsed coherent radiation is described, comprising a laser pulse source for generating laser light pulses, a resonant cavity including a non-linear medium for generating high harmonic pulses by an interaction of the laser light pulses with the non-linear medium, wherein the non-linear medium is arranged in an environment of reduced pressure.

A system is provided for measuring biometric signals, including at least two electrodes, wherein at least one is a capacitive electrode with a flexible structure, the system having a circuit for measuring the voltage between the two electrodes, where in some embodiments both electrodes are capacitive electrodes, and can be arranged as flexible belts, the system being suitable for measuring ECG signals and can be configured to measure also respiratory effort with Respiratory Inductive Plethysmography (RIP) technology, using the same electrodes which are used for measuring capacitively the ECG signals, a method being further provided for measuring biosignals with the system of the invention, the method further including generating an added current signal with a signal generator connected to the circuit, where the added signal has a frequency substantially removed from the frequency of the biosignal of interest, and by measuring the voltage signal of the frequency component corresponding to the added current signal one can determine fluctuations in the overall impedance and fluctuations in the capacitance of the circuit, and correct for fluctuations in the capacitance to obtain a corrected voltage signal representing the measured biosignal.

A driver for mounting a multiple sprocket arrangement to a bicycle rear axle arrangement. The multiple sprocket arrangement includes a sprocket assembly having a plurality of sprockets with different numbers of teeth and an adapter. The rear axle arrangement includes a hub. The driver includes an input torque transmitting profile for transmitting torque from between the sprocket assembly and the driver. A positioning section positions the sprocket assembly in the radial direction. External thread threadably receives the adapter and is disposed between the input torque transmitting profile and the positioning section. An output torque transmitting arrangement transmits torque between the driver and the hub.

An improved system of igniting a plasma using a rapid voltage rise and thus causing ions that may be pre-existing to create secondary electron emission or the like is provided. In one embodiment, the voltage rise can be timed to be comparable to the transit time of the electrons across the plasma. It can also be arranged to achieve a voltage rise in less than 1000 microseconds, to result in a transition time that is less than one hundred times the transit time, to maximize the emission of secondary electrons, or even to merely result in collision energies ranging from 5 to 500 electron volts. The transition time can be controlled through an ignition control that may be programmable, may involve charging output storage devices, or may involve delayed switching to supply the increased voltage to the plasma after the storage elements have been more fully charged.< / PTEXT>