51 results about "Chitosamine" patented technology

The invention discloses a polypeptide essence solution for improving the skin texture. The polypeptide essence solution is prepared from propylene glycol, diglycerin, glycerin, butanediol, nicotinamide, polyethylene glycol-8, a PEG / PPG-17 / 6 copolymer, hamamelis water, a glycerin acrylate / acrylic acid copolymer, a PVM / MA copolymer, palmitoyl hexapeptide-14, tripeptide-1, acetyl hexapeptide-8, pentapeptide-3, dipeptide diaminobutyryl benzyl amide diacetate, 1,2-hexanediol, betaine, tapioca starch, an ammonium acryl dimethyl taurine / VP copolymer, carbomer, acetyl chitosamine, a white willow barkextract, papain, sodium hyaluronate, octylene glycol, collagen, PEG-40 hydrogenated castor oil, hydroxyethyl cellulose, oligopeptide-1, a wild soybean seed extract, carnosine, disodium EDTA, octyl hydroxamic acid, rosa damascene flower oil and water. The polypeptide essence solution takes polypeptide tightening molecules as a main raw material, can awaken the skin vitality, maintain the skin elasticity, enhance the tightness, ameliorate fine lines, brighten the skin color, improve the skin texture, and rejuvenate the skin.

The invention discloses a composition for improving skin color and a whitening cosmetic. The composition comprises tranexamic acid, acetyl chitosamine and beta-nicotinamide mononucleotide. The tranexamic acid, the acetyl chitosamine and the beta-nicotinamide mononucleotide are compounded, the beta-nicotinamide mononucleotide is combined with the tranexamic acid and the acetyl chitosamine, pigmentation caused by ultraviolet rays or other skin irritation can be inhibited, and skin pigmented spots related to pigmentation are effectively prevented or improved. The acetyl chitosamine can improve transdermal absorption of effective components such as the tranexamic acid and the beta-nicotinamide mononucleotide, has a whitening effect, and can achieve a synergistic whitening effect when being used together with the tranexamic acid and the beta-nicotinamide mononucleotide, so that the tranexamic acid, the acetyl chitosamine and the beta-nicotinamide mononucleotide can achieve whitening and brightening effects at a low concentration, and are stable, safe and non-irritant.

The invention belongs to the technical field of skincare and discloses a skin whitening and repairing composition and a preparation method thereof. The skin whitening and repairing composition is prepared from, by weight, 0.1-2 parts of phytosterol, 0.01-1 part of bisabolol, 0.5-5 parts of azone, 0.1-2 parts of VE oil, 0.5-5 parts of nicotinamide, 0.1-3 parts of tranexamic acid, 0.1-2.5 parts of arbutin, 0.1-1.5 parts of VC ethyl ether, 0.1-1.8 parts of inositol, 0.01-1 part of acetyl chitosamine, 0.01-0.12 part of glabridin and 0.01-0.2 part of coating resveratrol. The preparation method includes the step that phytosterol, bisabolol, azone, VE oil, nicotinamide, tranexamic acid, arbutin, VC ethyl ether, inositol, acetyl chitosamine, glabridin and coating resveratrol are subjected to constant-temperature well mixing and emulsification to obtain a cream. The skin whitening and repairing composition has efficacies of skin whitening, freckle removing and skin repairing.

The invention provides a plant extract yeast lotion composition with a moisture retention function and a preparation method thereof. The lotion composition is prepared from tara gum, licorice root extracts, bifidobacterium longum lysate, bacillus fermentation products, yeast extracts, sodium hyaluronate, acetyl chitosamine, dipotassium glycyrrhizinate, 1,3-propylene glycol, polyethylene glycol, EDTA disodium and the balance water and preservative. The preparation method includes the following steps that after sodium hyaluronate, acetyl chitosamine, dipotassium glycyrrhizinate, 1,3-propylene glycol, polyethylene glycol and EDTA disodium are mixed with water, the temperature is preserved at 85 DEG C, so raw materials are completely dissolved and then cooled to 50 DEG C, tara gum, licorice root extracts, bifidobacterium longum lysate, bacillus fermentation products, yeast extracts and preservative are added and evenly stirred, and the plant extract yeast lotion composition is obtained. The composition does not contain essence or pigment, so the whole formula is safer.

The invention discloses anti-wrinkle essence which comprises a functional component, an auxiliary component and water, wherein the functional component comprises the following raw materials by weight percent: 0.03-0.3% of small-molecule sodium hyaluronate, 0.3-3% of acetyl chitosamine, 0.3-3% of an alpinia galangal extract, 1-3% of acetyl tetrapeptide-9, 1-5% of a chondrus crispus extract, 0.5-2% of a hibiscus abelmoschus seed extract, 2-6% of glycerin and 2-6% of butanediol. The adopted alpinia galangal extract is a natural plant active ingredient capable of promoting the synthesis of macromolecule hyaluronic acid. A small molecule or fragment hyaluronic acid in the skin can be transformed into the macromolecule hyaluronic acid, so that the problem that hyaluronic acid is difficult to absorb is effectively solved. The essence has excellent clinical manifestation in the skincare effects of preserving moisture, resisting ageing and removing winkles.

The invention discloses freckle-removing essence and a preparation process thereof. According to the technical scheme, the essence is prepared from the following components in parts by weight: 2-3 parts of vitamin C derivative, 0.8-1.5 parts of vitamin E, 1-2 parts of nicotinamide, 1-1.2 parts of acetyl chitosamine, 2-5 parts of angelica extract, 1-2 parts of titanium dioxide, 10-15 parts of humectant, 0.2-0.5 part of antibacterial preservative and 80-120 parts of deionized water. By adopting the technical scheme, a quick freckle-removing effect can be achieved, and the traditional Chinese medicine components can achieve the freckle-removing effect as well as gradually consolidate the freckle-removing curative effect.

The invention discloses an aroma slow-released heat-not-burn cigarette and an aroma slow-release method thereof. The surface of a cigarette core material is provided with a slow-release film made froma slow-release agent. The slow-release agent is prepared from one or more of pullulan, konjac glucomannan, chitosan, maltodextrin, polyoxyethylene, lac, guar gum, carboxymethyl cellulose, gelatin, chitosamine, sodium alginate, carrageenan, pectin, guar gum, Arabic gum, agar, modified starch or polyethylene glycol. A mass ratio of the slow-release agent to the cigarette core material is 1:100-30:100. Phase change of the slow-release agent is realized along with temperature changes of the heat-not-burn cigarette in a smoking process, and consequently at least part of the slow-release film on the surface of the cigarette core material is damaged, and low-boiling-point and volatile components in aroma substances and a smoking agent in the cigarette core material are uniformly and slowly released in the smoking process to guarantee great experience in smoking of the heat-not-burn cigarette.

The invention discloses a composite humectant. The composite humectant comprises, by weight, 10-13 parts of acetyl chitosamine, 15-18 parts of tremella polysaccharide, 18-20 parts of betaine, 25-28 parts of erythritol and 28-30 parts of mycose. The invention also discloses a preparation method of the composite humectant. The composite humectant is a natural and safe hygroscopic agent and humectant, can be used for all personal care moisturizing products and lotions such as facial cleansers, toner and smoothing toner, has good moisturizing effects, makes skin fresh and cool, is mild and non-greasy, can be used in the sunscreen products and after-sun soothing products and provides mild and cool moisturizing effects.

The invention discloses whitening moisturizing cleaning cream and a preparation method thereof. The whitening moisturizing cleaning cream is mainly prepared from the following materials in parts by weight: white fungus extracts, coix seed oil, orchid extracts, acetyl chitosamine, arbutin, cocamidopropyl betaine, sodium laureth sulfate, acrylicester copolymer, propanetriol dioctadecanoate, EDTA disodium, hydroxypropyltrimethyl ammonium chloride hyaluronic acid, 1,3-butanediol, imadazolidinyl urea, water and extracting solution of Chinese traditional medicine; the extracting solution of the Chinese traditional medicine is prepared by mixing curcuma, nux vomica, dried rehmannia root, cynanchum atratum and herba leonuri according to a mass ratio of 3:5:9:15:12, adding ethyl alcohol to the mixture, and performing reflux extraction. The prepared whitening moisturizing cleaning cream can penetrate into the skin to reduce existing melanin, activate cells and remove facial spots, has functions of repairing the epidermis, increasing the water content of the epidermis and increasing the water content of the cuticle, and ensures that the skin is exquisite, white and moistened.

The invention relates to the technical field of eye masks, in particular to eye-brightening and glowing stay-up eye mask essence and a preparation method thereof. The eye-brightening and glowing stay-up eye mask essence is prepared from the following raw materials of deionized water, a component A, a component B, a component C, a component D and a component E, wherein the component A comprises 1,3-propylene glycol, allantoin, trehalose, acetyl chitosamine, sclerotium gum, and disodium EDTA, the component B comprises butylene glycol and hydrolyzed sodium hyaluronate, the component C comprises nicotinamide and magnesium ascorbyl phosphate, the component D comprises olea europaea fruit oil and a solubilizer, and the component E comprises a palmitoyl hexapeptide compound conditioner, an acetyltetrapeptide compound conditioner, a carnosine compound conditioner, a gentiana lutea root extract conditioner, a cornus officinalis fruit extract conditioner, a saccharomyces lysate extract conditioner, a herba centellae conditioner, a chlorella extract conditioner, a glycerol caprylate compound humectant, and an ethylhexylglycerin compound humectant. The eye mask essence is prepared in gradientstirring and temperature decreasing modes, full and even mixing of raw materials is promoted, biological activity of the raw materials is also ensured, and aging of periorbital skin can be effectively relieved.

The invention discloses a repairing and whitening composition and a preparation method thereof. The repairing and whitening composition contains acetyl chitosamine, glabridin, hydrogenated lecithin, butyl methoxydibenzoylmethane, tocopherol, piperine, dipotassium glycyrrhizinate, potassium methoxysalicylate, tranexamic acid, alpha-arbutin, nicotinamide, a camellia extract and 3-o-ethyl ascorbic acid. According to the whitening action mechanism, the whitening effect is enhanced in an oriented multi-target multi-way mode, and butyl methoxydibenzoylmethane resists ultraviolet damage; dipotassiumglycyrrhizinate and acetyl chitosamine have the effects of reducing inflammation and ultraviolet stimulation; arbutin and glabridin inhibit tyrosinase activity; tocopherol inhibits tyrosine from beingoxidized into dopa; 3-o-ethyl ascorbic acid reduces dopaquinone into dopa; glabridin inhibits the activity of dopa pigment tautomerase and the activity of DHICA oxidase; tranexamic acid and nicotinamide inhibit melanin transport; nicotinamide and potassium-4-methoxysalicylate promote epidermis renewal; and eight target points act together and coordinate with each other to achieve the whitening effect.

The invention relates to the field of plant extracts, in particular to a whitening and brightening composition and a preparation method thereof. The whitening and brightening composition is at least prepared from the following raw materials: 20-60 parts of a herba selaginellae extract, 10-30 parts of a tomato extract, 3-10 parts of an ambrette seed extract, 5-20 parts of acetyl chitosamine, 3-18 parts of hyaluronic acid, 1-10 parts of hydrolyzed hyaluronic acid, 1-8 parts of dipotassium glycyrrhizinate and 10-30 parts of deionized water.

The invention relates to the technical field of a health care product, and in particular provides a health care product capable of improving bones and joints and a preparation method of the health care product, wherein the health care product is mainly prepared from the following raw materials in parts by weight: as for active ingredients: 10-40 parts of calcium carbonate, 15-40 parts of chitosamine hydrochloride and 10-30 parts of chondroitin sulfate, and as for accessories: 0.1-1 part of glucose essence and 1-5 parts of a thin-film coating agent. The preparation method of the health care product capable of improving bones and joints comprises five steps, namely preparing powder, mixing, granulating, mixing materials and tabletting, and coating. The health care product provided by the invention is high in calcium content, good in effect and good in absorption, and the health care product, by supplementing calcium and promoting osteoblastic cell proliferation, has a function of enhancing bone density so as to take better effects on preventing and improving osteoporosis and improving life level of middle aged and elderly people; and the health care product is low in cost and is applicable to extensive popularization and application. The preparation method of the health care product provided by the invention is simple and efficient, high in active ingredient utilization rate and suitable for industrial popularization.

The invention discloses an anti-wrinkle and anti-aging whitening mask. The anti-wrinkle and anti-aging whitening mask is prepared from the following raw materials in parts by weight: 70 to 80 parts ofpurified water, 1.5 to 2 parts of acetyl chitosamine, 0.8 to 1 part of sodium polyglutamate, 2.5 to 3 parts of cetostearyl alcohol, 0.8 to 1 part of isodecyl citrate, 5 to 6 parts of aloe extract, 3to 4 parts of witch hazel leaf extract, 3 to 4 parts of pleurotus salmoneostramineus extract, 3 to 4 parts of stauntonia leucantha fermentation extract, 8 to 10 parts of grape seed oil, 2.5 to 3 partsof sodium myristoyl sarcosinate, 2.5 to 3 parts of hydroxyethyl cellulose and 2.5 to 3 parts of inositol hexaphosphate. Through synergistic effect of components, the anti-wrinkle and anti-aging whitening mask has a prominent whitening effect, elastase inhibition activity, anti-wrinkle effect and anti-aging effect. Meanwhile, the anti-wrinkle and anti-aging whitening mask has excellent moisturizing effect and good anti-allergy effect, and can provide skin repair and protection from multiple aspects.

The invention provides a preparation method of a polypeptide wrinkle-removal repair essence. The polypeptide wrinkle-removal repair essence is prepared from the following components in parts by weight: water, butanediol, biosaccharide-1, dendrobium candidum extract, chitosamine, nano-silicone oil, starfish regeneration and repair factors, asiaticoside, papain, vitamin A palmitate, 1,2-hexanediol,p-hydroxyacetophenone, water-soluble ceramide, heparin sodium, methylparaben, sodium hyaluronate, xanthan gum, EDTA (ethylene diamine tetraacetic acid) disodium, and EGF (epidermal growth factor). Thepolypeptide wrinkle-removal repair essence has the advantages that the preparation is easy, and the polypeptide wrinkle-removal repair essence is suitable for large-scale industrialized production; the functions of removing skin wrinkles, improving skin textures, delaying skin aging and the like are realized, the components are natural and safe, and the polypeptide wrinkle-removal repair essenceis suitable for large-scale application.

The invention relates to plant essence and a preparation method thereof. The plant essence is prepared from the following components in parts by weight: 58 to 63 parts of distilled water, 8 to 12 parts of sodium hyaluronate, 5 to 8 parts of biosaccharide gum-1, 8 to 12 parts of butylene glycol, 2 to 5 parts of trehalose, 2 to 3 parts of hydroxyethyl cellulose, 8 to 10 parts of 1,2-hexanediol, 0.5to 1 part of herba selaginellae extract, 0.5 to 2 parts of chili extract, 5 to 8 parts of acetyl chitosamine, 2 to 4 parts of dipotassium glycyrrhizinate, 0.01 to 0.05 part of p-hydroxyacetophenone and 1 to 2 parts of methylparaben. The plant essence prepared according to the ratio has the advantages of relaxing and conditioning skin and keeping moisture of the skin.

The invention discloses a pig feed phagostimulant, a preparation method and an application method . The pig feed phagostimulant comprises the following raw materials in percentage by mass: 15-25% of sodium glutamate, 0.2-0.5% of disodium 5'-guanylate, 0.2-0.6% of disodium 5'-inosinate, 0.3-0.7% of neohesperidin dihydrochalcone, 19.3-25% of chitosamine chelate and 55-65% of silicon dioxide. After being adding to pig feed and uniformly mixed, the pig feed phagostimulant can obviously improve the palatability of the pig feed, promote the ingestion of pigs continuously and improve the growth performance of the pigs.

The invention discloses a medical sodium hyaluronate gel. The main components of the gel include sodium hyaluronate extracted from cockscombs, and sodium hyaluronate is mucopolysaccharide composed of the disaccharide repeating units of (1-beta-4)D-glucuronic acid-(1-beta-3)N-acetyl-D-chitosamine. The medical sodium hyaluronate gel is aseptic after bacterial filtration and aseptic process control, and can be used of preventing or reducing the postoperative adhesion of abdominal (pelvic) cavity operations as a filling agent; and the medical sodium hyaluronate gel can be matched with a disposal aseptic injection needle to be used for the injection in the ophthalmology, the surgery and the joint cavity, for example, the gel can be used as a viscoelastic substance of orthopedic operation joint cavity injection or an ophthalmologic operation.

The invention discloses a lavender seedling growing method. The method comprises the following steps that lavender residue leaves are subjected to ethyl alcohol ultrasonic digestion to obtain a lavender extractive; garden soil, peat moss, zeatin, coco coir, plant ash and river sand are taken for fermentation, and nutrient soil is prepared; branch terminal buds planted with the improved variety areselected for cutting out cuttings and soaked with a rooting powder solution containing ABT number 6 rooting powder, chitosamine and mannitol, a slotting machine is filled with the nutrient soil and the lavender extractive, then, the cutting is inserted into the slotting machine, the machine is covered with a film, and cutting cultivation is performed; after the cutting grows, transplanting can beperformed; water-fertilizer management is performed. The seedling growing method is simple and effective, high in operability, capable of saving materials, low in cost and high in production efficiency, raw materials are easy to obtain, cultivated lavender seedling rooting is rapid, the root system is vigorous and developed, the seedling percentage is high, the survival rate is high, growth and development are good, and rapid propagation can be achieved.

The invention discloses a dogwood fruit pulp-vanilla pod flour. The flour comprises the following raw materials by weight: 200 to 220 parts of wheat, 10 to 12 parts of walnut kernel, 5 to 7 parts of dogwood fruit pulp, 4 to 6 parts of peach blossom, 3 to 5 parts of powder of creeping acroptilon all-grass, 2 to 4 parts of powder of Potentilla glabra leaf, 0.5 to 0.9 part of vanilla pod powder, 7 to 8 parts of Gorgon fruit powder, 15 to 17 parts of fine konjak powder, 6 to 7 parts of polyghace seche, 4 to 6 parts of Curculigo orchioides, 3 to 6 parts of longspur epimedium, 0.4 to 0.6 part of chitosamine, a proper amount of amylase and a proper amount of papain. According to the invention, wheat are soaked in decocted fluid of the traditional Chinese medicines like polyghace seche and Curculigo orchioides at first, so the flour has health care effects like kidney warming and yang invigoration; papain is cured by chitosamine, so cured papain has heat resistance and heat increasing activity and reaction time of papain is reduced; due to addition of amylase and papain, the contents of polypeptide and polysaccharides in the flour are increased and the flour can be easily absorbed by the human body; and the taste and dietary structure of the flour are improved due to addition of abundant nutritional components like walnut kernel and dogwood fruit pulp.

A chitosamine preparation for increasing the power of plant to resist disease and the yield of plant is prepared through sequentically dissolving chitosamine, potassium sorbate and VC in water in weight ratio of 1:(0.05-0.16):2.8:(35-45), stirring, dissolving citric acid in water in weight ratio of 1:(8-12), and slowly adding the solution of citric acid to above-said solution while stirring.

The invention discloses a self-foaming essence and a preparation method thereof. The self-foaming essence is prepared from deionized water, glycerinum, butanediol, sodium hyaluronate, glycine betaine, acetyl chitosamine, nicotinamide, xanthan gum, glyceryl laurate, mipa-lauryl sulfate TEA salt, polyoxyethylene lauryl ether monosuccinate sodium sulfonate, hydroxyethyl acrylate / sodium acryloyldimethyl taurate copolymer, sodium hydroxide, arbutin, tocopheryl acetate, purslane extracting solution, MATRIXYL3000, an algae extract, an essence, a preservative and a foaming agent, wherein the foaming agent is Novec HFE-7100, PhoenoMulse CE-4 or BB 61. The self-foaming essence is capable of obviously improving the muscle state, so that the skin is tender and bright, and winkles are smoothed.

The present invention discloses a plant gene activator capable of making plant root system develop, increasing chlorophyll raising utilization rate of fertilizer, making plant self-body to resist several diseases and various adverse conditions. The composition of said activator contains (wt%) salicylic acid 0.1-10, linolenic acid 0.5-20, chitosamine 1-30, C18-C24 mixed fatty acid 10-60, fulvic acid 1-20 and emulsifier 5-20. The application of said activator can raise quality of agricultural products, can greatly raise yield of crops, and it is non-toxic and harmless to animal, plant and humanbody, and has no pollution.

The invention discloses a holly propagation method which comprises the following steps: adding absolute ethyl alcohol containing alpha-terpilenol into holly residual leaves, and carrying out ultraphonic digestion to obtain holly extractive; taking garden soil, peat moss, zeatin, coir dust, vermiculite powder and river sand, adding water, and carrying out fermentation to obtain nutrient soil; scissoring half-lignified twigs, and soaking the twigs in a rooting powder solution containing rooting powder ABT6, chitosamine and mannitol; inserting cuttings in a slotting machine filled with the nutrient soil and the holly extractive, covering a film and cultivating; after the cuttings take root, carrying out hardening-seedling and transplanting, and carrying out water and fertilizer management after seedling recovering. The holly propagation method is simple to operate, high in repeatability, low in cost and high in production efficiency; the raw materials are easy to obtain; the method can ensure holly cuttings to be high in rooting percentage, high in survival rate and developed in root growth; and the obtained seedlings are high in quality, so that the cultivation period is effectivelyshortened, and the holly propagation coefficient is increased.

The invention discloses a polypeptide anti-aging composition adopting an inclusion technology and a preparation method thereof. The polypeptide anti-aging composition is prepared from the following components in parts by weight: 10-15 parts of carnosine, 8-12 parts of acetyl chitosamine, 5-9 parts of glutathione, 6-10 parts of an oligopeptide-1, and 6-10 parts of N-hydroxysuccinimide; the acetyl chitosamine and the N-hydroxysuccinimide are located in a hollow ball, and the carnosine, the oligopeptide-1 and the glutathione are adsorbed on the circumferential face of the hollow ball and coat theacetyl chitosamine and the N-hydroxysuccinimide; polysaccharide wrapping and anti-oxidation matching technologies are adopted, so that the oligopeptide-1, the glutathione and the carnosine are evenlywrapped in the acetyl chitosamine and the N-hydroxysuccinimide; and through the wrapping and anti-oxidation matching technologies, the states such as oxidation, discoloration and inactivation causedby air and external factors are isolated, so that raw material active ingredients achieve the due functions in the client-side using process.

The invention discloses a thin layer chromatography scanning detection method for chitosamine hydrochloride. The method has the advantages of simplicity and convenience, quickness, accuracy, reliability and stability, and comprises the following steps: step (1), dripping sample liquid and standard liquid on a same efficient thin layer silica gel plate GF254, unfolding, and airing; step (2), spraying the acetone solution of aniline-diphenylamine-trichloroacetic acid on the efficient thin layer silica gel plate uniformly, or soaking the plate for 1 min, airing, and baking and dyeing; step (3), adopting a thin layer scanner to conduct thin layer chromatography scanning, so that the chitosamine hydrochloride RF and the peak area integral quantity are obtained; calculating the relationship between the standard liquid quality and the peak area integral quantity through thin layer chromatograph management software, and calculating the chitosamine hydrochloride content of the sample according to the peak area integral quantity of the sample liquid. The invention further discloses a method for preparing the chitosamine hydrochloride by adopting antarctic krill as a raw material through acidolysis, so that the comprehensive utilization of the antarctic krill is enriched, the utilization ratio is increased, and the economic benefit is increased.

The invention discloses a shaking emulsion skin care product. The shaking emulsion skin care product comprises a water phase and an oil phase, wherein the water phase comprises 3-o-ethyl ascorbic acid, water, nicotinamide, panthenol, trehalose, betaine, acetyl chitosamine, beta-glucan, glycerin, dipropylene glycol, an avena sativa kernel extract, butanediol, 1,2-pentanediol, glyceryl caprylate, caprylic hydroxamic acid and p-hydroxyacetophenone; and the oil phase is mainly composed of caprylic acid / capric acid triglyceride, Argania spinosa kernel oil and citrus aurantium amara flower oil or yolk oil or rosa damascena flower oil. The oil phase and the water phase are in a two-phase separation state, and better separate design of the water phase and the oil phase is facilitated; a larger proportion and more varieties of water-soluble active ingredients can be added to the water phase and a larger proportion and more varieties of oil-soluble active ingredients can be added to the oil phase without too much consideration of compatibility and stability between water and oil materials. A convenient space is added for the functional design of the product.

The invention relates to a chitosamine hydrochloride pellet preparation and its preparation method. By using glucosamine extracted from marine organism as an active ingredient, the chitosamine hydrochloride pellet preparation comprises glucosamine pellets and a coating layer. The glucosamine pellets contain the following materials, by weight, 70-90% of chitosamine hydrochloride with the particle size being 30-100 microns, 10-20% of blank drug core pellets with the particle size being 0.2-1 mm, 2-10% of a binder and 0.1-1% of a flow aid. According to the chitosamine hydrochloride pellet preparation, as the whole drug release body is composed of multiple drug release units, abnormal drug release behaviors of an individual unit will not influence the whole situation. Thus, an ideal overall drug release rate can be obtained, and an expected blood concentration can be achieved. Therefore, an ideal curative effect is achieved, and the irritant effect on the gastrointestinal tract can be reduced.

The invention relates to whitening essence capable of being used immediately after being mixed. The whitening essence is prepared from whitening powder and permeation promoting essence, wherein the whitening powder is prepared from the following components: 3-o-ethyl ascorbic acid, tranexamic acid, nicotinamide, acetyl chitosamine and hesperidin methyl chalcone; the permeation promoting essence isprepared from the following permeation promoting components: bis-(diethoxy) diethylene glycol cyclohexane 1, 4-dicarboxylate, PEG / PPG-14 / 7 dimethyl ether and polyglycerol-10 eicosate / tetradecanedioicacid ester; and the whitening powder and the permeation promoting essence are contained in two independent cavities of a container respectively according to a ratio and are mixed to obtain the whitening essence capable of being used immediately after being mixed. According to the whitening essence provided by the invention, the permeation promoting components of the permeation promoting essence can be used for enhancing the permeation and absorption of whitening components to the greatest extent and the percutaneous permeability of the water-soluble whitening components can be effectively promoted; the whitening powder and the permeation promoting essence are mixed according to the ratio and can be used immediately after being mixed, so that the defects that whitening products on the market are easy to discolor and inactivate can be overcome; and the whitening essence can be stably stored in a shelf life and the whitening effect is obvious.