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Cosmetic composition favorable for keeping biological activity of epidermal growth factor (EGF)

A technology of epidermal growth factor and cosmetic composition, which is applied in the field of compositions that help maintain the biological activity of epidermal growth factor, and can solve problems such as complex ingredients, difficulty in maintaining biological activity, and impact on biological activity

Inactive Publication Date: 2012-04-11
INFINITUS (CHINA) CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] However, as a biologically active polypeptide molecule, epidermal growth factor is difficult to maintain in the actual cosmetic formula, because the ingredients in the cosmetic formula are relatively complex and different formula ingredients have a greater impact on its biological activity. Some may degrade and lose biological activity

Method used

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  • Cosmetic composition favorable for keeping biological activity of epidermal growth factor (EGF)

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0041] Skin care gels with EGF:

[0042] The components and percentages thereof that make up the above-mentioned skin care gel product are:

[0043] EGF0.0000005

[0044] Hydrolyzed Collagen Powder 0.20

[0045] Sodium Hyaluronate 0.50

[0046] Silk peptide powder 0.60

[0047] Palmitoyl Pentapeptide 1.00

[0048] Carnosine 0.20

[0049] Carbomer 0.50

[0050] Triethanolamine 0.25

[0051] Glycerin 14.00

[0052] Preservatives 0.10

[0053] Deionized water balance

[0054] The preparation method of above-mentioned skin care gel product, comprises the following steps:

[0055] (1) Mix carbomer and sodium hyaluronate with glycerin and deionized water, stir to dissolve;

[0056](2) Add hydrolyzed collagen powder, silk peptide powder, palmitoyl pentapeptide, carnosine, and preservatives to the above solution and stir to dissolve evenly, then add EGF and stir evenly;

[0057] (3) Triethanolamine is dissolved in water to form a 10% solution;

[0058] (4) Add the...

Embodiment 2

[0062] Lotion containing EGF:

[0063] The components and percentages of the above lotion products are as follows:

[0064] EGF0.0000008

[0065] Hydrolyzed Collagen Powder 0.50

[0066] Sodium hyaluronate 0.02

[0067] Silk peptide powder 0.60

[0068] Palmitoyl Pentapeptide 0.50

[0069] Carnosine 0.21

[0070] Glycerin 6.00

[0071] Disodium edetate 0.10

[0072] Genma preservative 0.10

[0073] Aminomethyl propanol 0.01

[0074] Deionized water balance

[0075] The preparation method of above-mentioned skin care lotion product, comprises the following steps:

[0076] (1) First mix disodium edetate, sodium hyaluronate, glycerin, and deionized water, and stir to dissolve evenly;

[0077] (2) Add hydrolyzed collagen powder, silk peptide powder, palmitoyl pentapeptide, carnosine, and preservatives to the above solution and stir to dissolve evenly;

[0078] (3) Add EGF and stir evenly;

[0079] (5) Add aminomethyl propanol and stir evenly, adjust the pH val...

Embodiment 3

[0082] Body lotion with EGF:

[0083] The components and percentages thereof that make up the above body lotion are:

[0084] Component A:

[0085] PEG-100 stearate 2.00

[0086] Monoglycerides 1.50

[0087] PEG-8 beeswax 1.50

[0088] Polydimethylsiloxane 2.00

[0089] Squalane 4.00

[0090] Isopropyl palmitate 6.00

[0091] Cetearyl alcohol 0.50

[0092] Methylparaben 0.20

[0093] Propylparaben 0.10

[0094] B component:

[0095] Deionized water balance

[0096] Disodium edetate 0.10

[0097] Glycerin 5.00

[0098] Xanthan gum 0.30

[0099] C component:

[0100] EGF0.000001

[0101] Hydrolyzed Collagen Powder 1.00

[0102] Sodium Hyaluronate 0.30

[0103] Palmitoyl Pentapeptide 3.50

[0104] Deionized water 1.00

[0105] Silk peptide powder 1.20

[0106] Carnosine 0.80

[0107] D component:

[0108] Genma preservative 0.10

[0109] Fragrance 0.10

[0110] The preparation method of above-mentioned body lotion is:

[0111] Disperse the xanthan gum...

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Abstract

The invention discloses a cosmetic composition favorable for keeping the biological activity of an epidermal growth factor (EGF). The composition mainly comprises the EGF, hydrolyzed collagen powder, sodium hyaluronate, silk peptide powder, palmitoyl pentapeptide and carnosine. The cosmetic composition disclosed by the invention has the characteristics that polypeptides with different structures and molecules are used as main raw materials, polysaccharides are compounded, and various components are similar to the EGF in structure, thereby protecting the EGF; and under the protective action of multiple components which are reasonably combined and matched, the biological activity of the EGF in a cosmetic formula is kept.

Description

technical field [0001] The invention relates to the field of cosmetics, in particular to a composition that helps maintain the biological activity of epidermal growth factor. Background technique [0002] At present, skin care products containing epidermal growth factor (EGF) stimulate the metabolism of epidermal cells through epidermal growth factor (EGF), accelerate the process of new skin cells replacing aging cells, promote the growth of skin cells, and keep skin cells young, thus To achieve the purpose of keeping the skin young and rejuvenated. Because its effect is better than that of general skin care products, and it is natural and has no side effects, epidermal growth factor (EGF) has become one of the effective ingredients of high-end beauty and skin care products, and is very popular in the market. [0003] However, as a biologically active polypeptide molecule, epidermal growth factor is difficult to maintain in the actual cosmetic formula, because the ingredien...

Claims

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Application Information

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IPC IPC(8): A61K8/73A61K8/64A61K8/65A61Q19/08
Inventor 李建华刘光荣马忠华
Owner INFINITUS (CHINA) CO LTD
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