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A method and device for treating a mammalian organism to obtain a desired local or systemic physiological or pharmacological effect is provided. The method includes administering a sustained release drug delivery system to a mammalian organism in need of such treatment at an area wherein release of an effective agent is desired and allowing the effective agent to pass through the device in a controlled manner. The device includes an inner core or reservoir including the effective agent, an impermeable tube which encloses portions of the reservoir, and a permeable member at an end of the tube.

A monitor configuration system which communicates with a physiological sensor, the monitor configuration system including one or more processors and an instrument manager module running on the one or more processors. At least one of the one or more processors communicates with the sensor and calculates at least one physiological parameters responsive to the sensor. The instrument manager controls the calculation, display and / or alarms based upon the physiological parameters. A configuration indicator identifies the configuration profile. In one aspect of the invention, the physiological sensor is a optical sensor that includes at least one light emitting diode and at least one detector.

There is disclosed herein a tube of material (1) having a seam (12) extending between a proximal end and a distal end, two edges (10a, 10b) of the material meeting and at least partially overlapping along the seam (12) and being sewn together at the seam by stitches (21, 22, 24) of relatively flexible thread (20), the thread of one or more of the stitches (22, 24) passing from a first side (12a) of the overlapped edges (10a, 10b) of material, through both layers of overlapped material, crossing a relatively rigid member (30) which is disposed on a second, opposite side (12b) of the overlapped edges of material, and passing back to the first side (12a). There is further disclosed an implant delivery catheter (40) incorporating the tube of material (1), and associated methods for its manufacture.

Organs and other tissue structures are isolated and perfused with a therapeutic agent. Isolation is effected by endovascularly positioning catheters having occlusion balloons within the arteries or other blood vessels which supply blood to the organ. Similarly, blood flow from the organ back to the patient's circulatory system is blocked by endovascularly positioning one or more catheters carrying occlusion members within the veins or other blood vessels leading from the organ. The therapeutic agent may then be perfused through the organ in either an antegrade or retrograde fashion using the endovascularly positioned catheters while maintaining isolation.

Methods for forming a film on a substrate in a semiconductor manufacturing process A reaction chamber a substrate in the chamber are provided. A ruthenium based precursor, which includes ruthenium tetroxide dissolved in a mixture of at least two non-flammable fluorinated solvents, is provided and a ruthenium containing film is produced on the substrate.

The present invention comprises a method for deploying an aortic valve prosthesis. This valve prosthesis may include any of the known aortic valves including, but not limited to, stented and unstented bioprosthetic valves, stented mechanical valves, and expandable or self-expanding valves, whether biological or artificial. The method involves the steps of: making a first opening leading to the left atrium; passing a valve prosthesis through the opening and into a cardiac chamber of the left side of the heart using a first manipulation instrument; making a second opening in the arterial system and advancing one end of a second manipulation instrument through the arterial opening and into the aforementioned cardiac chamber; securing the second manipulation instrument to the valve prosthesis; and using the second manipulation instrument to retract at least some portion of the valve prosthesis out of the aforementioned cardiac chamber.

A monitor configuration system which communicates with a physiological sensor, the monitor configuration system including one or more processors and an instrument manager module running on the one or more processors. At least one of the one or more processors communicates with the sensor and calculates at least one physiological parameters responsive to the sensor. The instrument manager controls the calculation, display and / or alarms based upon the physiological parameters. A configuration indicator identifies the configuration profile. In one aspect of the invention, the physiological sensor is a optical sensor that includes at least one light emitting diode and at least one detector.

Electronic device operable by an user for regulating and controlling ambient parameters, such as ambient temperature, comprising a processing unit, a display device for displaying selectable control functions and setting parameters related to a set of desired ambient conditions and a selection / control unit for selecting by the user at least one control function or setting parameter from among a set of displayed control functions or setting parameters. The device comprises an interactive display of a dot matrix type able to display to a user variable indications comprising at least the specific control function associated with each of said selection / control unit according to the specific selection made by the user.

A control architecture for electric vehicle wireless power transmission systems that may be segmented so that certain essential and / or standardized control circuits, programs, algorithms, and the like, are permanent to the system and so that other non-essential and / or augmentable control circuits, programs, algorithms, and the like, may be reconfigurable and / or customizable by a user of the system. The control architecture may be distributed to various components of the wireless power system so that a combination of local or low-level controls operating at relatively high-speed can protect critical functionality of the system while higher-level and relatively lower speed control loops can be used to control other local and system-wide functionality.

Apparatus for resecting a diseased heart valve, the apparatus comprising: a body portion; a first handle and a second handle; a cutting blade; a set of retaining arms; a pass-off tool having a first attachment device configured to selectively engage the first handle attached to the body portion so as to allow placement of the second handle of the body portion adjacent to the diseased heart valve, and a controller tool having a second attachment device at the distal end thereof, the second attachment device configured to selectively engage the second handle attached to the body portion so as to allow positioning of the body portion adjacent to the diseased heart valve, a cutting blade actuator configured to cause the cutting blade to selectively rotate, and a retaining arm actuator configured to selectively position the set of retaining arms from the contracted state to the expanded state.

A storage area network (SAN) has one or more host digital data processors are coupled to one or more storage devices (e.g., LUNs) by an interconnect, e.g., a fiber channel-based fabric. Switches or switch-like interfaces on the interconnect fabric define zones or regions in which certain hosts can access certain storage devices, but not other storage devices. Scanners, e.g., operating within agents associated with the hosts, collect information regarding the regions and, more particularly, the hosts, storage devices and interconnect elements that make them up. A manager operating, for example, on a further digital data processor disambiguates information from the regions and discerns the topology of the portion of the SAN spanned by the regions. Thus, it identifies as a virtual SAN elements from regions that have at least one common storage device with at least one other region.

A peripheral nerve stimulator can be used to stimulate a peripheral nerve to treat essential tremor, Parkinson tremor, and other forms of tremor. The peripheral nerve stimulator can be either a noninvasive surface stimulator or an implanted stimulator. Stimulation can be electrical, mechanical, or chemical. Stimulation can be delivered using either an open loop system or a closed loop system with feedback.

The invention provides a medical device having a catheter and one or more expandable constricting / occluding members. The catheter is adapted for use with therapeutic or diagnostic devices, including an angioplasty / stent catheter and an atherectomy catheter. The constrictor / occluder is mounted at the distal end of the catheter. Manometers may be mounted distal to one or more constrictors for measuring pressure distal to the constrictor(s). Methods of using the devices are disclosed for preventing distal embolization during extracranial or intracranial carotid artery, vertebral artery, or coronary artery procedures, or procedures involving any vessel having collateral flow by reversing flow in the diseased vessel.

A real identity biometric authentication device includes a USB thumb drive form factor, with a biometric sensor and designated device processor and stored instructions in firmware which perform authentication in a secure manner, independent of processing and storage resources on a host platform. The device and authentication process require biometric data and are secured against effects of malware or other security risks presented by applications running on the host platform. During an enrollment process, a unique encrypted enrollment biometric token is created using biometric data and uploaded securely to an authentication server. During an authentication process, the encrypted enrollment biometric token is downloaded to the real identity authentication device firmware and is decrypted on the device. The biometric data obtained from the decrypted data and is compared with live, real-time biometric data obtained from the user, for example, by a real-time fingerprint scan. If the real-time biometric data and the enrolled, decrypted biometric data match, the user is authenticated.

A method and apparatus for transporting syringes containing radioactive material. The apparatus includes a radiopharmaceutical pig having an inner chamber in which a sharps container can be secured. The sharps container has a housing and an attachable cap. The method includes assembling the radiopharmaceutical pig so that the chamber of the radiopharmaceutical pig contains the syringe in the sharps container housing. The radiopharmaceutical pig is disassembled, where upon the syringe is removed, discharged, and then replaced in the sharps container housing. The cap of the sharps container is affixed to the housing of the sharps container, thus enclosing the contaminated syringe therein. The radiopharmaceutical pig is assembled so that its chamber contains the sharps container and the syringe. The radiopharmaceutical pig is transported to a disposal area, where it is disassembled and the sharps container containing the syringe is placed in a particular disposal container.

A tamper-evident rigid plastic food container system wherein the outer periphery of the mating surfaces of the lid and tray are permanently bonded together after the food product has been placed in the tray, a set of perforated rows at an inner periphery, the interconnect of which needs to be torn into order to open the lid. Intentional, inadvertent or malicious ingress into the container can only be made by tearing at the perforations thereby evidencing the potential tampering and contamination of the packaging contents. The lid and tray edges may further include mechanical interference fits, including snap-fit grips that may be of the releaseably lockable kind to permit sealing, release and re-sealing multiple times without deterioration in reliability, and which can further prevent or minimize leakage of liquid food product.

A notebook computer that has a keyboard, a navigation input device (e.g., a touchpad or mouse) and a sketch input device (usually an integrated sketch pad and stylus). The sketch input device operates in an absolute coordinate mapping mode and can be tracked on the display when hovering or touching. It draws digital ink when touching. Whenever the digital ink runs into existing text notes the text is reflowed around the sketch. A movement on an input device can either select text or draw digital ink depending on which input device was used. The computer can have sketch tool buttons operable with a stylus. The navigation and sketch input devices can be disjoint or overlapping. Variations of the sketch input device include a second touch pad that works with a finger and a stylus that works without a sketch pad.

The invention provides a medical device having a catheter and one or more expandable constricting / occluding members. The catheter has a lumen communicating with a port at its distal end. The lumen and port are adapted for introduction of therapeutic or diagnostic devices, including an angioplasty / stent catheter and an atherectomy catheter, into a vertebral or basilar artery. The constrictor / occluder is mounted proximal to the port of the catheter. Manometers may be mounted distal to one or more constrictors for measuring pressure distal to the constrictor(s). Methods of using the devices for preventing distal embolization during vertebral and / or basilar procedures by reversing blood flow in the vertebral artery toward the subclavian artery are disclosed.

A cartridge for holding a test specimen with an extremely small volume. The cartridge has a test chamber and a vestibule through which the test fluids are inserted into the test chamber. The cartridge has a stopper having a pair of seals, the first of which seals the test chamber inlet between the vestibule and the test chamber, and the second of which seals the mouth of the vestibule so that when the stopper is in place, the test chamber is closed to the admission of air or other contaminants and the vestibule is similarly closed against escape of the overflow from the test chamber.

A controller equipped with a user interface having a separate schedule review mode, including methods of accessing and / or programming such devices, are disclosed. The controller may include a user interface that can be utilized to initiate a scheduling routine having a separate schedule review mode for displaying one or more schedule parameters of the controller without initiating the editing mode. An illustrative method of accessing a schedule on a controller coupled to a user interface may include the steps of initializing a scheduling routine within the controller, initiating a schedule review mode within the controller, displaying one or more schedule parameters for at least one period on the user interface, and exiting the scheduling routine. One or more of the schedule parameters can be modified, if desired, by initiating a separate editing mode within the controller.

The invention relates to a method and apparatus for color matching of slightly colored objects which are transparent, diffusing an absorbent, by acuminating a small error of the objects with a first bunch of optical fibers. A second bunch of optical fibers is used to pick up the light back scattered from the area of the objects. The second fibers are located inside of the illuminating fibers. The light is measured at 3 wavelengths that correspond to blue, green and red colors and the pigmentation of the object is calculated as a difference between the red and blue spectrum components. Presentation of the brightness is calculated to be proportional to the green spectrum component. The pigmentation and brightness is then compared with the same perimeters of a standard shape pallet. The invention is particularly suitable for color matching the teeth in the mouth with dental prosthesis and dental restorative materials.

An implantable stent-like device for treating and occluding arteriovascular malformations (AVMs), fistulas, varicose veins or the like. More particularly, this invention relates to an implant body that includes an open-cell shape-transformable polymer structure that provides stress-free means for occluding an AVM without applying additional pressures an any distended walls of the AVM. In one embodiment, the shape-transformable polymer is a shape memory polymer implant body that self-deploys from a temporary shape to a memory shape. In another embodiment, the shape memory polymer structure is capable of a temporary compacted shape for carrying about the struts of an expandable stent for self-deployment to occlude an aneurysm.

A vial for storing multiple doses of a substance to be dispensed into one or more syringes or other delivery devices. The vial has a body, a variable-volume storage chamber within the body for storing multiple doses of the substance therein, and a one-way valve connectable in fluid communication with a syringe or other delivery device. The one-way valve is moveable relative to the body between first and second positions (i) one of which permits the valve to open so that substance from the variable-volume storage chamber can flow therethrough and into the syringe or other delivery device connected in fluid communication therewith, and (ii) one of which prevents the valve from opening.

A pre-assembled pipe coupling for joining and sealing two grooved-ended pipe segments without disassembling the coupling is disclosed. The coupling has a housing with upper and lower arcuate housing segments and left and right bridge segments. Each bridge segment has at least one set of dihedrally angled faces that engage corresponding faces each in the upper and lower housing segments. Drawing the upper and lower segments inwardly together along a first axis, presses each bridge segment inward along a second axis roughly tangential to the first axis. All segments are loosely pre-assembled with bolts and nuts into a coupling and all segments each have radially inwardly projecting lands that mate with end grooves in the pipes to be joined. The coupling also has a one-piece circular sealing gasket that has an inward circumferential and centrally positioned pipe stop that has an inner diameter smaller than an outer diameter of the pipes to be joined. The gasket has two circumferential sealing lips axially outward from the pipe stop, the inner diameter each sealing lip larger than the outer diameter of the pipe segments to be joined.Method for joining and sealing two grooved-ended pipe segments with a pre-assembled pipe coupling, without disassembling the coupling, is also disclosed.

A wellhead seal assembly forms a metal-to-metal seal between inner and outer wellhead members. A metal seal ring has inner and outer walls separated by a slot. An energizing ring has a C-ring captured on its outer surface. When the energizing ring is moved farther into the slot, the C-ring is forced from its pocket and engages a profile on the seal ring, locking the energizing ring to the seal assembly.