The invention provides an intelligent human body sign mobile phone monitoring system, which comprises a human body sign acquisition module, a monitoring mobile phone and a cloud server, wherein the human body sign acquisition module is used for monitoring the body sign signal of a monitored object; the monitoring mobile phone is used for receiving body sign signals of the human body sign acquisition module, preprocessing the body sign signals so as to eliminate baseline drift to obtain preprocessed body sign data, storing the preprocessed body sign data and analyzing the body sign data; and the cloud server is used for receiving an equipment recognition code of the monitoring mobile phone as well as preprocessed sign signals and alarm signals, storing the body sign data and the alarm signals in corresponding items, in a database, of the monitored object, analyzing the body sign data and the alarm signals so as to generate medical advice information and transmitting the medical advice information to the corresponding monitoring mobile phone and preset associated terminal equipment. The monitoring system disclosed by the invention has the characteristics of mobile operation, simple and convenient use, long-term continuous work supporting, diagnosis result intelligent display, abnormal physiological status alarm, wireless data transmission and the like.