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337 results about "Absorption spectroscopy" patented technology

Absorption spectroscopy refers to spectroscopic techniques that measure the absorption of radiation, as a function of frequency or wavelength, due to its interaction with a sample. The sample absorbs energy, i.e., photons, from the radiating field. The intensity of the absorption varies as a function of frequency, and this variation is the absorption spectrum. Absorption spectroscopy is performed across the electromagnetic spectrum.

Reagentless analysis of biological samples by applying mathematical algorithms to smoothed spectra

Apparatus and method for determining at least one parameter, e. g., concentration, of at least one analyte, e. g., urea, of a biological sample, e. g., urine. A biological sample particularly suitable for the apparatus and method of this invention is urine. In general, spectroscopic measurements can be used to quantify the concentrations of one or more analytes in a biological sample. In order to obtain concentration values of certain analytes, such as hemoglobin and bilirubin, visible light absorption spectroscopy can be used. In order to obtain concentration values of other analytes, such as urea, creatinine, glucose, ketones, and protein, infrared light absorption spectroscopy can be used. The apparatus and method of this invention utilize one or more mathematical techniques to improve the accuracy of measurement of parameters of analytes in a biological sample. The invention also provides an apparatus and method for measuring the refractive index of a sample of biological fluid while making spectroscopic measurements substantially simultaneously.
Owner:ABBOTT LAB INC

Method and apparatus for a tunable diode laser spectrometer for analysis of hydrocarbon samples

The present invention provides an down hole apparatus and method for ultrahigh resolution spectroscopy using a tunable diode laser (TDL) for analyzing a formation fluid sample downhole or at the surface to determine formation fluid parameters. In addition to absorption spectroscopy, the present invention can perform Raman spectroscopy on the fluid, by sweeping the wavelength of the TDL and detecting the Raman-scattered light using a narrow-band detector at a fixed wavelength. The spectrometer analyzes a pressurized well bore fluid sample that is collected downhole. The analysis is performed either downhole or at the surface onsite. Near infrared, mid-infrared and visible light analysis is also performed on the sample to provide an onsite surface or downhole analysis of sample properties and contamination level. The onsite and downhole analysis comprises determination of aromatics, olefins, saturates, gas oil ratio, API gravity and various other parameters which can be estimated by correlation, a trained neural network or a chemometric equation.
Owner:BAKER HUGHES INC

Catheter-based mid-infrared reflectance and reflectance generated absorption spectroscopy

A catheter based method and apparatus for reflectance generated absorption spectral analysis of chronic inflammatory vascular conditions such as seen with atherosclerotic plaque within a blood vessel or other body cavity or compartment. The use of a bright mid range infrared light (mid-IR) source yields detectable reflected optical signals that may be sampled from an area smaller or larger than the typical diameter of a mammalian cell. The mid-IR light is delivered at selected mid-infrared wavenumbers. Using the apparatus and methods, the reflectance spectra and reflectance generated absorption spectra of a target tissue can be compared to reference spectra to identify and distinguish normal epithelium from tissue containing physiological markers indicative of vascular disease or other inflammatory conditions.
Owner:RGT UNIV OF CALIFORNIA

Method for creating chemical sensors using contact-based microdispensing technology

Contact based rigid pin tool technology is utilized to print one or more indicator chemistries on an optical array or a disposable sheath configured on such arrays. Each indicator chemistry contains predetermined material, such as, light energy absorbing dye(s), optically responsive particles, etc., whose optical characteristics change in response to the target ligand or analyte. By spectrally monitoring such changes using fluorescence and / or absorption spectroscopy, detection and / or quantitation of the target ligand or analyte can be obtained.
Owner:LAWRENCE LIVERMORE NAT SECURITY LLC

Method and device for detecting gases by absorption spectroscopy

A method and device for measuring a concentration of a preselected gas in a gas sample are disclosed. The device comprises a Herriott type multipass cell (10) having a center axle (74) and a housing (80A, 80B) surrounding and spaced from the axle to provide a tubular sample cavity (84). The gas sample is pumped through the sample cavity via apertures (154, 156) provided in opposed ends of the axle. A first mirror (44) and a second mirror (46) are supported at opposed ends of the axle. A light source, e.g. a laser or LED, is provided for emitting a light beam into the sample cavity via an entry aperture (30) in the first mirror, the light beam having a wave length at which the preselected gas strongly absorbs. The beam is reflected between the mirrors for a number of times before exiting the cell via an exit aperture (48) in the second mirror and impinging on a detector (52). The device further comprises a reference detector (32) for monitoring the intensity of the unattenuated light beam and a detector for detecting the intensity of light transmitted through the second mirror after a single pass through the cell. The light source is operatively connected to a heat control assembly having a heat sink and the gas sample is passed said heat sink to augment temperature control of the light source.
Owner:ECOTEC INT HLDG LLC

Spectroscopic imaging device employing imaging quality spectral filters

Techniques for providing spectroscopic imaging integrates an acousto-optic tunable filter (AOTF), or an interferometer, and a focal plane array detector. In operation, wavelength selectivity is provided by the AOTF or the interferometer. A focal plane array detector is used as the imaging detector in both cases. Operation within the ultraviolet, visible, near-infrared (NIR) spectral regions, and into the infrared spectral region, is achieved. The techniques can be used in absorption spectroscopy and emission spectroscopy. Spectroscopic images with a spectral resolution of a few nanometers and a spatial resolution of about a micron, are collected rapidly using the AOTF. Higher spectral resolution images are recorded at lower speeds using the interferometer. The AOTF technique uses entirely solid-state components and requires no moving parts. Alternatively, the interferometer technique employs either a step-scan interferometer or a continuously modulated interferometer.
Owner:US DEPT OF HEALTH & HUMAN SERVICES

Method and apparatus for a tunable diode laser spectrometer for analysis of hydrocarbon samples

The present invention provides an down hole apparatus and method for ultrahigh resolution spectroscopy using a tunable diode laser (TDL) for analyzing a formation fluid sample downhole or at the surface to determine formation fluid parameters. In addition to absorption spectroscopy, the present invention can perform Raman spectroscopy on the fluid, by sweeping the wavelength of the TDL and detecting the Raman-scattered light using a narrow-band detector at a fixed wavelength. The spectrometer analyzes a pressurized well bore fluid sample that is collected downhole. The analysis is performed either downhole or at the surface onsite. Near infrared, mid-infrared and visible light analysis is also performed on the sample to provide an onsite surface or downhole analysis of sample properties and contamination level. The onsite and downhole analysis comprises determination of aromatics, olefins, saturates, gas oil ratio, API gravity and various other parameters which can be estimated by correlation, a trained neural network or a chemometric equation.
Owner:BAKER HUGHES INC

Multisensor probe for tissue identification

A multisensor probe for continuous real-time tissue identification. The multisensor probe includes a tissue penetrating needle, a plurality of sensors useful in characterizing tissue and a position sensor to measure the depth of the needle into the tissue being diagnosed. The sensors include but are not limited to an optical scattering and absorption spectroscopy sensor, an optical coherence domain reflectometry sensor, an electrical impedance sensor, a temperature sensor, a pO2 sensor, a chemical sensor and other sensors useful in identifying tissue. The sensors may take the form of a plurality of optical fibers extending through said needle. A retractable sheath may be disposed around the distal section of the needle to protect the needle when not in use. The sheath retracts when the probe is inserted into tissue and the position of the sheath relative to the needle may be measured to determine the needle's depth. Systems and methods for tissue identification are also provided.
Owner:BIOLUMINATE

Method and device for detecting gases by absorption spectroscopy

A method and device for measuring a concentration of a preselected gas in a gas sample are disclosed. The device comprises a Herriott type multipass cell (10) having a center axle (74) and a housing (80A, 80B) surrounding and spaced from the axle to provide a tubular sample cavity (84). The gas sample is pumped through the sample cavity via apertures (154, 156) provided in opposed ends of the axle. A first mirror (44) and a second mirror (46) are supported at opposed ends of the axle. A light source, e.g. a laser or LED, is provided for emitting a light beam into the sample cavity via an entry aperture (30) in the first mirror, the light beam having a wave length at which the preselected gas strongly absorbs. The beam is reflected between the mirrors for a number of times before exiting the cell via an exit aperture (48) in the second mirror and impinging on a detector (52). The device further comprises a reference detector (32) for monitoring the intensity of the unattenuated light beam and a detector for detecting the intensity of light transmitted through the second mirror after a single pass through the cell. The light source is operatively connected to a heat control assembly having a heat sink and the gas sample is passed said heat sink to augment temperature control of the light source.
Owner:ECOTEC INT HLDG LLC

Method and system for preventing deposition on an optical component in a spectroscopic sensor

Provided are novel methods of preventing deposition on an optical component in an absorption spectroscopy measurement cell. The methods involve performing an absorption spectroscopy measurement of a sample gas introduced into the cell, and introducing a flow of purge gas from a purge gas inlet pipe across a critical surface of the optical element at a velocity effective to prevent deposition on the critical surface. The gas inlet is disposed adjacent said critical surface. Also provided are devices for practicing the inventive method, measurement cells useful in absorption spectroscopy measurements, apparatuses for performing an absorption spectroscopy measurement and semiconductor processing apparatuses. The invention allows for the performance of accurate spectroscopic measurements. Because deposits are prevented from forming on the surface of an optical element, interference therefrom can effectively be avoided.
Owner:LAIR LIOUIDE POUR LETUD ET LEXPL DES PROCEDES GEORCLAUDE +1

Method And Apparatus For Determining Marker Gas Concentration Using An Internal Calibrating Gas

A method and an apparatus for measuring the concentration of a specific gas component of a gas mixture including another gas whose concentration is independently known using light absorption spectroscopy are provided. A method and an apparatus for assessing human airway inflammation by measuring the concentration of exhaled NO and CO2 present in orally exhaled breath using light absorption spectroscopy are also provided. NO concentration is determined at the time during breath sampling corresponding to a known exhaled CO2 concentration. Methods and apparatus are further provided for measuring NO concentration in orally exhaled human breath that analyze breath emanating from the lower airways and lungs, while excluding breath from the nasal cavity. They include steps and apparatus for discarding initially exhaled breath, flowing breath through an analysis chamber using a vacuum pump and flowing breath through an analysis chamber using a vacuum pump at an initial flow rate and later at a flow rate higher than the initial flow rate.
Owner:EKIPS TECH

Opening gas multi-element monitoring instrument and monitoring method

The invention discloses a multi-wavelength high-sensitivity online monitor of multi-component NH3 and H2O based on semiconductor laser absorption spectroscopy. It contains host chassis and open long-path system. Equip power receptacle, switch, fiber connector and data transmission interface. It is characterized in that: there are near-infrared semiconductor laser, semiconductor laser controller, phase-locked amplifier, signal generator, data collecting and controlling module and infrared detector in host chassis which is connected with field optical system by fiber. Open optical system contains send-receive optical telescope and multielement reflector array. Optical telescope has input and output fiber couplers. The device realizes simultaneous testing of gas multi-component by using multi-wavelength and frequency division multi-signal detecting technique.
Owner:ANHUI INST OF OPTICS & FINE MECHANICS - CHINESE ACAD OF SCI

Packaged Chip For Multiplexing Photonic Crystal Microcavity Coupled Waveguide And Photonic Crystal Slot Waveguide Devices For Chip-Integrated Label-Free Detection And Absorption Spectroscopy With High Throughput, Sensitivity, Specificity, And Wide Dynamic Range

Systems and methods for chip-integrated label-free detection and absorption spectroscopy with high throughput, sensitivity, and specificity are disclosed. The invention comprises packaged chips for multiplexing photonic crystal microcavity waveguide and photonic crystal slot waveguide devices. The packaged chips comprise crossing waveguides to prevent leakage of fluids from the microfluidic channels from the trenches or voids around the light guiding waveguides. Other embodiments are described and claimed.
Owner:OMEGA OPTICS

Method and system for contamination detection and monitoring a lithographic exposure tool and operating method for the same under controlled atmospheric conditions

By using highly efficient detection techniques, such as chromatography and absorption spectroscopy, one or more contaminants may be identified and the concentration thereof may quantitatively be determined. In this way, the adverse effect on critical components of exposure tools, such as reticles and lenses in the form of, for instance, deposited inorganic salts, may significantly be reduced and the process performance may be enhanced.
Owner:ADVANCED MICRO DEVICES INC +1

Surface-emitting semiconductor laser

A laser suitable for intra-cavity laser absorption spectroscopy and for telecommunication system comprises a Bragg mirror, a multiple quantum well active region and an anti-reflective coating together with a second mirror spaced from the coating to define an external cavity, the free spectral range of the sub-cavity defined by the coating and the active region being less than two times the bandwidth of the coating and the bandwidth of the Bragg mirror being at least as great as the free spectral range of the sub-cavity.
Owner:PICARRO +1

Non-invasive, miniature, breath monitoring apparatus

A rugged, miniature, spectroscopic gas analyzer apparatus for rapid, non-invasive, multi-component breath monitoring and analysis and subsequent determination of Q or other medical diagnostic applications. The system is comprised of one or more IR emitters focussed by optical elements through a low volume sample cell receiving a sample input of a patient's breath for analysis. The patient either at rest or during exercise, inhales C2H2—SF6 mixtures (balance of oxygen and nitrogen) which is subsequently monitored upon exhalation for CO2, H2O, C2H2, and SF6 which can be employed to determine Q directly and accurately. Measurements are performed in real-time or via post-processing of stored original data. Due to its small size, ruggedness, and low power consumption, the monitor can conveniently be employed in the field or data can also be retrieved remotely using telemetry. The miniature analyzer operates on the principle of infrared absorption spectroscopy and allows very precise concentration measurements of the analytes of interest, without any bias or interference from other matrix components.
Owner:OAK CREST INST OF SCI

X-ray techniques using structured illumination

ActiveUS20160320320A1Great x-ray fluxEnhanced signalImaging devicesX-ray tube electrodesX Ray Emission SpectroscopySmall-angle X-ray scattering
This invention discloses a method and apparatus for x-ray techniques using structured x-ray illumination for examining material properties of an object. In particular, an object with one or more regions of interest (ROIs) having a particular shape, size, and pattern may be illuminated with an x-ray beam whose cross sectional beam profile corresponds to the shape, size and pattern of the ROIs, so that the x-rays of the beam primarily interact only with the ROIs. This allows a greater x-ray flux to be used, enhancing the signal from the ROI itself, while reducing unwanted signals from regions not in the ROI, improving signal-to-noise ratios and / or measurement throughputThis may be used with a number of x-ray measurement techniques, including x-ray fluorescence (XRF), x-ray diffraction (XRD), small angle x-ray scattering (SAXS), x-ray absorption fine-structure spectroscopy (XAFS), x-ray near edge absorption spectroscopy, and x-ray emission spectroscopy.
Owner:SIGRAY INC

Systems and apparatus relating to the monitoring and/or controlling of selective catalytic reduction processes

A system for the monitoring and / or controlling emission levels of nitrogen oxide and a reductant from a stream of combustion exhaust, wherein the internal combustion engine includes a SCR unit disposed in the stream of combustion exhaust between an upstream conduit and a downstream conduit, the SCR unit having a catalyst that is configured to catalytically reduce nitrogen oxides contained in the combustion exhaust to elemental nitrogen in the presence of a reductant and oxygen, and wherein the internal combustion engine further includes a reductant injector; the system comprising: a laser absorption spectroscopy unit that is disposed in the downstream conduit and configured to measure the concentration level of at least nitrogen oxide and the reductant in the exhaust; and a control unit.
Owner:GENERAL ELECTRIC CO

Method and Apparatus for the Detection of Trace Gas Species Using Multiple Line Integrated Absorption Spectroscopy

An apparatus and method are used to enhance the sensitivity of a spectrometer (sensor) for trace gas species detection by employing an external cavity continuously tunable CW quantum cascade laser and integrating the absorption spectra across multiple lines of the species. With this method the absorption spectra of NO2 is continuously recorded across the R-branch from 1628.8 cm−1 to 1634.5 cm−1. By integrating the resulting spectra, the detection sensitivity for NO2 is improved by a factor of 15 compared to the sensitivity achieved using single line laser absorption spectroscopy with the same apparatus. This procedure offers much shorter data acquisition times for the real-time monitoring of trace gas species compared with adding repeated scans of the spectra to improve the signal-to-noise ratio.
Owner:ADELPHI UNIVERSITY

Detection of contamination in imaging systems by fluorescence and/or absorption spectroscopy

Process and system for detection of contamination in an imaging system, including providing an imaging system having one or more element having a surface for reflecting or refracting first incident radiation; mounting with respect to at least one of the one or more element one or more detector capable of sensing third radiation emitted or transmitted by one or more contaminant on the surface of the one or more element when second radiation is absorbed by the one or more contaminant; applying the first incident radiation and / or the second radiation to the at least one element; and detecting with the one or more detector the third radiation emitted or transmitted by the one or more contaminant.
Owner:ADVANCED MICRO DEVICES INC

Linked extendable gas observation system for infrared absorption spectroscopy

A modular system for gas analysis has a first gas cell that receives and passes at least a portion of an infrared light beam through at least a portion of the first gas cell. A second gas cell disposed proximal to the first gas cell receives and passes at least a portion of the infrared light beam from the first gas cell through at least a portion of the second gas cell. At least a portion of the first gas cell and at least a portion of the second gas cell define a light path having an effective length. The system includes a means for adjusting the effective length of the light path to vary a property of the infrared light beam. Methods of making a variable effective length light path and methods of making a gas detector are also disclosed.
Owner:MKS INSTR INC

Background-free absorption spectroscopy using spectral differentiator

An absorption spectrometer provides improved rejection of background radiation signal by employing a frequency-swept laser signal without frequency dithering and performing an effective differentiation of output light from a test cell to eliminate these constant or slowly varying background radiation levels.
Owner:WISCONSIN ALUMNI RES FOUND

Cavity enhanced absorption spectroscopy with a laser modulation side-band frequency locked to the cavity

A cavity enhanced absorption spectrometer (CEAS) and method for controlling the same. The CEAS includes a coherent electro-magnetic radiation source, an electro-magnetic modulator that creates a sideband with an adjustable frequency that is offset from the radiation source frequency by imparting an adjustable frequency modulation to the radiation. The CEAS also includes a RF source that drives the electro-magnetic modulator and a cavity enhanced absorption resonator (CEAR) that receives the sideband. A detector measures the proximity of the frequency of the sideband relative to the resonant frequency of the CEAR and generates a proximity detector signal, which is converted by a controller to a control signal that controls at least one of the RF source and the resonant frequency of the CEAR such that the frequency of the sideband and the resonant frequency of the CEAR are adjusted to maintain a predetermined proximity therebetween.
Owner:ENTANGLEMENT TECH

Infrared spectrometer

The present invention provides a method and apparatus for detecting, by absorption spectroscopy, an isotopic ratio of a sample, by passing first and second laser beams of different frequencies through the sample. Two IR absorption cells are used, a first containing a reference gas of known isotopic ratio and the second containing a sample of unknown isotopic ratio. An interlacer or reflective chopper may be used so that as the laser frequencies are scanned the absorption of the sample cell and the reference cell are detected alternately. This ensures that the apparatus is continuously calibrated and rejects the baseline noise when phase sensitive detection is used.
Owner:UK RES & INNOVATION LTD

Absorption spectroscopy apparatus and method

An absorption spectroscopy apparatus having a fluid inlet and a fluid outlet. The apparatus includes a sample cell including an axis, a side wall having at least one curved reflective surface arrayed about the axis and facing inwardly with respect to the cell such that a beam of energy directed against a predetermined location on the reflective surface is reflected back and forth off the reflective surface and remains in substantially the same plane while inside the cell, and at least one port in the sidewall. The apparatus also includes at least one source / detector reflector having a curved profile in a plane extending perpendicular to the axis of the cell. The reflector is positioned with respect to the port of the cell to reflect energy through the port of the cell and against the predetermined location on the reflective surface of the side wall of the cell.
Owner:FLIR SURVEILLANCE

Sensitive and Compact Sensor Employing a Visible Diode Laser and A High Finesse Optical Cavity for Trace Gas Detection (NO2)

A sensor with high sensitivity and selectivity for the detection of NO2 uses a simple diode laser operating nominally at 405 nm in the visible region, a high finesse optical cavity and a low noise photon detector. The sensor employs the multimode broad output of the diode laser with the high finesse optical cavity in an essentially off-axis arrangement that can provide large path lengths of the order of a km in a small volume cell. The detected absorption signal corresponds to multiple line integrated absorption spectroscopy (MLIS). Because the sensor uses visible radiation it can employ optics in the visible region that are normally less expensive. Also, the sensor is free from interference from atmospheric water vapor which is often a severe problem for sensors based on mid-infrared quantum cascade lasers operating in the mid-infrared (for example 1650 cm−1) region.
Owner:ADELPHI UNIVERSITY

Gas analyzing apparatus with built-in calibration gas cell

A gas analyzing apparatus for laser absorption spectroscopy measurement includes a laser light source to generate laser beam with a specific wavelength absorbed by a component being measured in sample gas, a laser light source drive controller to control driving of the laser light source, an optical detector arranged at a location where the laser beam is received, a gas cell for measurement of the sample gas which is arranged on an optical path of the laser beam going from the laser light source to the optical detector, and a computing unit to calculate a concentration of the component being measured in the sample gas in accordance with a detection signal of the optical detector. Further, the gas analyzing apparatus has at least one calibration gas cell where calibration gas is filled with, and a calibration gas cell mounting mechanism capable of locating one of the calibration gas cells in a removable manner on the optical path of the laser beam.
Owner:SHIMADZU SEISAKUSHO CO LTD
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