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1879results about "Interferometric spectrometry" patented technology
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Multi-pixel high-resolution three-dimensional imaging radar
A three-dimensional imaging radar operating at high frequency e.g., 670 GHz radar using low phase-noise synthesizers and a fast chirper to generate a frequency-modulated continuous-wave (FMCW) waveform, is disclosed that operates with a multiplexed beam to obtain range information simultaneously on multiple pixels of a target. A source transmit beam may be divided by a hybrid coupler into multiple transmit beams multiplexed together and directed to be reflected off a target and return as a single receive beam which is demultiplexed and processed to reveal range information of separate pixels of the target associated with each transmit beam simultaneously. The multiple transmit beams may be developed with appropriate optics to be temporally and spatially differentiated before being directed to the target. Temporal differentiation corresponds to a different intermediate frequencies separating the range information of the multiple pixels. Collinear transmit beams having differentiated polarizations may also be implemented.
Owner:CALIFORNIA INST OF TECH
Method to suppress artifacts in frequency-domain optical coherence tomography
ActiveUS7330270B2Radiation pyrometryMaterial analysis using wave/particle radiationFrequency domain optical coherence tomographySignificant difference
One embodiment of the present invention is a method for suppressing artifacts in frequency-domain OCT images, which method includes (a) providing sample and reference paths with a significant difference in their chromatic dispersion (b) correcting for the effects of the mismatch in chromatic dispersion, for the purpose of making artifacts in the OCT image readily distinguishable from the desired image.
Owner:CARL ZEISS MEDITEC INC
In-situ method of analyzing cells
InactiveUS6165734AWidespread samplingEasy to masterRaman/scattering spectroscopyRadiation pyrometryHistological stainingBiology
A method of in situ analysis of a biological sample comprising the steps of (a) staining the biological sample with N stains of which a first stain is selected from the group consisting of a first immunohistochemical stain, a first histological stain and a first DNA ploidy stain, and a second stain is selected from the group consisting of a second immunohistochemical stain, a second histological stain and a second DNA ploidy stain, with provisions that N is an integer greater than three and further that (i) if the first stain is the first immunohistochemical stain then the second stain is either the second histological stain or the second DNA ploidy stain; (ii) if the first stain is the first histological stain then the second stain is either the second immunohistochemical stain or the second DNA ploidy stain; whereas (iii) if the first stain is the first DNA ploidy stain then the second stain is either the second immunohistochemical stain or the second histological stain; and (b) using a spectral data collection device for collecting spectral data from the biological sample, the spectral data collection device and the N stains are selected such that a spectral component associated with each of the N stains is collectable.
Owner:APPLIED SPECTRAL IMAGING
Method for simultaneous detection of multiple fluorophores for in situ hybridization and multicolor chromosome painting and banding
InactiveUS6066459AImprove throughputShorten the timeRaman/scattering spectroscopyRadiation pyrometryChromosome paintingFluorophore
A spectral imaging method for simultaneous detection of multiple fluorophores aimed at detecting and analyzing fluorescent in situ hybridizations employing numerous chromosome paints and / or loci specific probes each labeled with a different fluorophore or a combination of fluorophores for color karyotyping, and at multicolor chromosome banding, wherein each chromosome acquires a specifying banding pattern, which pattern is established using groups of chromosome fragments labeled with various fluorophore or combinations of fluorophores.
Owner:APPLIED SPECTRAL IMAGING
Interferometric back focal plane scatterometry with Koehler illumination
An interference spectroscopy instrument provides simultaneous measurement of specular scattering over multiple wavelengths and angles. The spectroscopy instrument includes an interference microscope illuminated by Koehler illumination and a video camera located to image the back focal plane of the microscope's objective lens while the path-length difference is varied between the reference and object paths. Multichannel Fourier analysis transforms the resultant intensity information into specular reflectivity data as a function of wavelength. This multitude of measured data provides a more sensitive scatterometry tool having superior performance in the measurement of small patterns on semiconductor devices and in measuring overlay on such devices.
Owner:ZYGO CORPORATION
Apparatus and method for the rapid spectral resolution of confocal images
A confocal scanning microscope apparatus and method is used to rapidly acquire spectrally resolved images. The confocal scanning microscope apparatus includes optics used to simultaneously acquire at least two points along a scan pattern on a sample plane of a sample, wherein the points include regions of the sample represented by at least two pixels. A detection arm is placed in the path of the light reflected, scattered, or emitted from the sample plane comprising a spectrometer having a slit for receiving such light and a detector array placed behind the spectrometer. The image corresponding to the at least two points is recorded on the first axis of said detector and the spectral resolution thereof is simultaneously recorded on the second axis of said detector. The confocal scanning microscope apparatus and method offers significant improvements to the current techniques for genetic sequencing, as well as significant improvements to traditional confocal scanning microscope applications.
Owner:DUKE UNIV
Optical imaging of induced signals in vivo under ambient light conditions
InactiveUS6748259B1Rapid detection and imaging and localization and targetingHigh sensitivityInterferometric spectrometryNanoinformaticsImaging processingTarget signal
A method for detecting and localizing a target tissue within the body in the presence of ambient light in which an optical contrast agent is administered and allowed to become functionally localized within a contrast-labeled target tissue to be diagnosed. A light source is optically coupled to a tissue region potentially containing the contrast-labeled target tissue. A gated light detector is optically coupled to the tissue region and arranged to detect light substantially enriched in target signal as compared to ambient light, where the target signal is light that has passed into the contrast-labeled tissue region and been modified by the contrast agent. A computer receives signals from the detector, and passes these signals to memory for accumulation and storage, and to then to image processing engine for determination of the localization and distribution of the contrast agent. The computer also provides an output signal based upon the localization and distribution of the contrast agent, allowing trace amounts of the target tissue to be detected, located, or imaged. A system for carrying out the method is also described.
Owner:J FITNESS LLC
Spectroscopic apparatus
InactiveUS20050046837A1Small sizeLarge angular dispersionRadiation pyrometryInterferometric spectrometryBandpass filteringLight beam
A spectroscopic apparatus which is compact in size and performs high-precision light-splitting with a large angular dispersion. An optical input-processing section outputs a filtered transmitted light, using a bandpass filter that transmits only wavelength bands at one period of an input light, and collects the filtered transmitted light to generate a collected beam. An optic includes a first reflection surface and a second reflection surface which are high but asymmetric in reflectivity, and causes the collected beam incident thereon to undergo multiple reflections within an inner region between the first reflection surface and the second reflection surface, to thereby cause split beams to be emitted via the second reflection surface. A received light-processing section performs received light processing of the beams emitted from the optic. A control section variably controls at least one of a filter characteristic of the bandpass filter and an optical length through the optic.
Owner:FUJITSU LTD
Intravascular optical coherence tomography system with pressure monitoring interface and accessories
ActiveUS20110178413A1PressureEasy to useRadiation pyrometryInterferometric spectrometryPhotovoltaic detectorsPhotodetector
An optical coherence tomography system and method with integrated pressure measurement. In one embodiment the system includes an interferometer including: a wavelength swept laser; a source arm in communication with the wavelength swept laser; a reference arm in communication with a reference reflector; a first photodetector having a signal output; a detector arm in communication with the first photodetector, a probe interface; a sample arm in communication with a first optical connector of the probe interface; an acquisition and display system comprising: an A / D converter having a signal input in communication with the first photodetector signal output and a signal output; a processor system in communication with the A / D converter signal output; and a display in communication with the processor system; and a probe comprising a pressure sensor and configured for connection to the first optical connector of the probe interface, wherein the pressure transducer comprises an optical pressure transducer.
Owner:LIGHTLAB IMAGING
Method to suppress artifacts in frequency-domain optical coherence tomography
ActiveUS20060171503A1Radiation pyrometryMaterial analysis using wave/particle radiationTomographyFrequency domain optical coherence tomography
One embodiment of the present invention is a method for suppressing artifacts in frequency-domain OCT images, which method includes (a) providing sample and reference paths with a significant difference in their chromatic dispersion (b) correcting for the effects of the mismatch in chromatic dispersion, for the purpose of making artifacts in the OCT image readily distinguishable from the desired image.
Owner:CARL ZEISS MEDITEC INC
Method and apparatus for optically analyzing a surface
InactiveUS20070091317A1Quick and efficient analysisEffectively and accurately characteristicRadiation pyrometryInterferometric spectrometryCharacterization testBroadband
Apparatus and methods are provided for analyzing surface characteristics of a test object using broadband scanning interferometry. Test objects amenable to these apparatus and methods include but are not limited to semiconductor wafers, semiconductor devices, metallic surfaces, and the like. An interferometry system is used to obtain an interferometry signal and related to data embodied in the signal representative of the test object surface. This signal and / or data is used to construct an n-dimensional function that includes an independent frequency variable and an independent time variable, and / or an n-dimensional function that includes an independent scale variable and an independent time variable, and / or a multi-domain function. These functions are compared with various models to obtain a best match that is then used to characterize the test object surface.
Owner:PHASE SHIFT TECH
Methods, systems and computer program products for optical coherence tomography (OCT) using automatic dispersion compensation
ActiveUS20070258094A1Extended processing timeRadiation pyrometryInterferometric spectrometryComputer scienceDispersion compensation
Methods, systems and computer program products for generating parameters for software dispersion compensation in optical coherence tomography (OCT) systems are provided. Raw spectral interferogram data is acquired for a given lateral position on a sample and a given reference reflection. A trial spectral phase corresponding to each wavenumber sample of the acquired spectral interferogram data is postulated. The acquired raw spectral data and the postulated trial spectral phase data are assembled into trial complex spectrum data. Trial A-scan data is computed by performing an inverse Fourier transform on the trial complex spectrum data and determining the magnitude of a result.
Owner:BIOPTIGEN
Fourier domain optical coherence tomography employing a swept multi-wavelength laser and a multi-channel receiver
ActiveUS20070002327A1Low costIncrease in the speed of each axial scanRadiation pyrometryInterferometric spectrometrySpectral domainLasing wavelength
The present invention is an alternative Fourier domain optical coherence system (FD-OCT) and its associated method. The system comprises a swept multi-wavelength laser, an optical interferometer and a multi-channel receiver. By employing a multi-wavelength laser, the sweeping range for each lasing wavelength is substantially reduced as compared to a pure swept single wavelength laser that needs to cover the same overall spectral range. The overall spectral interferogram is divided over the individual channels of the multi-channel receiver and can be re-constructed through processing of the data from each channel detector. In addition to a substantial increase in the speed of each axial scan, the cost of invented FD-OCT system can also be substantially less than that of a pure swept source OCT or a pure spectral domain OCT system.
Owner:CARL ZEISS MEDITEC INC
Systems and methods for endoscopic angle-resolved low coherence interferometry
InactiveUS20070133002A1Fast resultsEnhance its widespread applicabilityRadiation pyrometryRaman/scattering spectroscopyData acquisitionIn vivo
Fourier domain a / LCI (faLCI) system and method which enables in vivo data acquisition at rapid rates using a single scan. Angle-resolved and depth-resolved spectra information is obtained with one scan. The reference arm can remain fixed with respect to the sample due to only one scan required. A reference signal and a reflected sample signal are cross-correlated and dispersed at a multitude of reflected angles off of the sample, thereby representing reflections from a multitude of points on the sample at the same time in parallel. Information about all depths of the sample at each of the multitude of different points on the sample can be obtained with one scan on the order of approximately 40 milliseconds. From the spatial, cross-correlated reference signal, structural (size) information can also be obtained using techniques that allow size information of scatterers to be obtained from angle-resolved data.
Owner:DUKE UNIV
Imaging Systems Using Unpolarized Light And Related Methods And Controllers
Optical imaging systems are provided including a light source and a depolarizer. The light source is provided in a source arm of the optical imaging system. A depolarizer is coupled to the light source in the source arm of the optical imaging system and is configured to substantially depolarize the light from the light source. Related methods and controllers are also provided.
Owner:BIOPTIGEN
Method and apparatus for three-dimensional spectrally encoded imaging
ActiveUS20050128488A1Point become highRadiation pyrometryInterferometric spectrometryPhase sensitiveSingle mode fiber transmission
A method and apparatus for obtaining three-dimensional surface measurements using phase-sensitive spectrally encoded imaging is described. Both transverse and depth information is transmitted through a single-mode optical fiber, allowing this technique to be incorporated into a miniature probe.
Owner:THE GENERAL HOSPITAL CORP
Forward scanning imaging optical fiber probe
Probes, and systems and methods for optically scanning a conical volume in front of a probe, for use with an imaging modality, such as Optical Coherence Tomography (OCT). A probe includes an optical fiber having a proximal end and a distal end and defining an axis, with the proximal end of the optical fiber being proximate a light source, and the distal end having a first angled surface. A refractive lens element is positioned proximate the distal end of the optical fiber. The lens element and the fiber end are both configured to separately rotate about the axis so as to image a conical scan volume when light is provided by the source. Reflected light from a sample under investigation is collected by the fiber and analyzed by an imaging system. Such probes may be very compact, e.g., having a diameter 1 mm or less, and are advantageous for use in minimally invasive surgical procedures.
Owner:CALIFORNIA INST OF TECH
Method and apparatus for interferometry
InactiveUS20110235045A1High measurementImprove scanning accuracyRadiation pyrometryInterferometric spectrometryHelical computed tomographyEngineering
A method and an arrangement are provided for scalable confocal interferometry for distance measurement, for 3-D detection of an object, for OC tomography with an object imaging interferometer and at least one light source. The interferometer has an optical path difference not equal to zero at each optically detected object element. Thus, the maxima of a sinusoidal frequency wavelet, associated with each detected object element, each have a frequency difference Δf_Objekt. At least one spectrally integrally detecting, rastered detector is arranged to record the object. The light source preferably has a frequency comb, and the frequency comb differences Δf_Quelle are changed in a predefined manner over time in a scan during measuring. In the process, the frequency differences Δf_Quelle are made equal to the frequency difference Δf_Objekt or equal to an integer multiple of the frequency differences Δf_Objekt at least once for each object element.
Owner:UNIV STUTTGART
Optical heterodyne detection in optical cavity ringdown spectroscopy
The present invention relates to optical heterodyne detection cavity ringdown spectroscopy. In one aspect the invention relates to an optical system (1) comprising a ring-down cavity cell (3) defining a resonant optical cavity, means for directing coherent light selected from the group consisting of continuous or quasi-continuous light into said optical cavity (8, 9, 10, 11, and 12), means for altering the resonant optical cavity so as to generate a frequency shift of the coherent light in the optical cavity (6, 7), means for coupling said coherent light into the optical cavity and means for decoupling the frequency shifted coherent light out of said optical cavity (5, 6, 7), means for optically combining (10, 11, 12) said decoupled frequency shifted coherent light with another portion of coherent light not in optical communication with the optical cavity and means for optical heterodyne detection (13) of the intensity of said combined light. A method for optical detection is also described as well as methods and apparatus for detecting a parameter of a sample.
Owner:MACQUARIE RES
Optical heterodyne detection in optical cavity ringdown spectroscopy
InactiveUS7012696B2Efficient couplingImprove skillsRadiation pyrometryLaser detailsContinuous lightOptical cavity
Owner:MACQUARIE RES
Method and apparatus for three-dimensional spectrally encoded imaging
A method and apparatus for providing information associated with at least one portion of a sample can be provided. For example, at least one wavelength of electro-magnetic radiation provided on a sample can be encoded to determine at least one transverse location of the portion. A relative phase between at least one first electro-magnetic radiation electro-magnetic radiation being returned from a sample and at least one second electro-magnetic radiation returned from a reference can be obtained to determine at least one relative depth location of the portion. Further, the information of the portion can be provided based on the transverse location and the relative depth location. For example, the information can be depth information and / or three-dimensional information associated with the portion of the sample.
Owner:THE GENERAL HOSPITAL CORP
Birefringent interferometer
InactiveUS6421131B1Economical and simpleAccurate analysisOptical measurementsRadiation pyrometryWide fieldOn board
A birefringent interferometer system is described which uses nematic liquid crystal cells to produce variable optical path differences (OPD) between light of different polarization states that are interfered at a polarizing analyzer. Fixed retarders may also be incorporated to extend the range of OPD. The interferometer provides wide field-of-view, continuously variable path difference over a large range, and an on-board monitor of OPD for ensuring accurate settings of path difference, and hence, an accurate wavelength scale in the spectra produced by the apparatus. The system can further incorporate additional polarizing optics so it responds equally well to light of any incident polarization state without loss of efficiency.
Owner:CAMBRIDGE RES & INSTR
Spectroscopic apparatus
InactiveUS7304798B2Small sizeHigh-precision light-splittingRadiation pyrometryInterferometric spectrometryBandpass filteringLight beam
A spectroscopic apparatus which is compact in size and performs high-precision light-splitting with a large angular dispersion. An optical input-processing section outputs a filtered transmitted light, using a bandpass filter that transmits only wavelength bands at one period of an input light, and collects the filtered transmitted light to generate a collected beam. An optic includes a first reflection surface and a second reflection surface which are high but asymmetric in reflectivity, and causes the collected beam incident thereon to undergo multiple reflections within an inner region between the first reflection surface and the second reflection surface, to thereby cause split beams to be emitted via the second reflection surface. A received light-processing section performs received light processing of the beams emitted from the optic. A control section variably controls at least one of a filter characteristic of the bandpass filter and an optical length through the optic.
Owner:FUJITSU LTD
Process, System And Software Arrangement For A Chromatic Dispersion Compensation Using Reflective Layers In Optical Coherence Tomography (OCT) Imaging
ActiveUS20090196477A1Compensation for dispersionEasy to implementRadiation pyrometryInterferometric spectrometryFrequency spectrumReflective layer
A system, process and software arrangement are provided to compensate for a dispersion in at least one portion of an image. In particular, information associated with the portion of the image is obtained. The portion of the image can be associated with an interference signal that includes a first electromagnetic radiation received from a sample and a second electromagnetic radiation received from a reference. The dispersion in the at least one portion of the image can be compensated by controlling a phase of at least one spectral component of the interference signal.
Owner:THE GENERAL HOSPITAL CORP
Apparatus and method for cross axis parallel spectroscopy
ActiveUS20090273777A1Cascading convenienceImprove dynamic rangeRadiation pyrometryInterferometric spectrometrySpectroscopyElectromagnetic radiation
Owner:THE GENERAL HOSPITAL CORP
Apparatus and method for ranging and noise reduction of low coherence interferometry LCI and optical coherence tomography oct signals by parallel detection of spectral bands
ActiveUS20080094613A1Improve signal-to-noise ratioHigh sensitivityRadiation pyrometryDiagnostics using lightBandpass filteringSpectral bands
Apparatus and method for increasing the sensitivity in the detection of optical coherence tomography and low coherence interferometry (“LCI”) signals by detecting a parallel set of spectral bands, each band being a unique combination of optical frequencies. The LCI broad bandwidth source is split into N spectral bands. The N spectral bands are individually detected and processed to provide an increase in the signal-to-noise ratio by a factor of N. Each spectral band is detected by a separate photo detector and amplified. For each spectral band the signal is band pass filtered around the signal band by analog electronics and digitized, or, alternatively, the signal may be digitized and band pass filtered in software. As a consequence, the shot noise contribution to the signal is reduced by a factor equal to the number of spectral bands. The signal remains the same. The reduction of the shot noise increases the dynamic range and sensitivity of the system.
Owner:THE GENERAL HOSPITAL CORP
Spectrometry system with diffuser
ActiveUS20150292948A1Reduce crosstalkShorten the lengthInterferometric spectrometryMaterial analysis by optical meansSensor arrayImage resolution
Owner:VERIFOOD
High-speed transmission system comprising a coupled multi-cavity optical discriminator
This invention generally relates to an optical filter for a fiber optic communication system. A coupled multi-cavity optical filter may be used, following a directly modulated laser source, and converts a partially frequency modulated signal into a substantially amplitude modulated signal. The optical filter may compensate for the dispersion in the fiber optic transmission medium and may also lock the wavelength of the laser source.
Owner:II VI DELAWARE INC
Spectroscopic ellipsometer and polarimeter systems
InactiveUS7633625B1Reduce biasRadiation pyrometryInterferometric spectrometryBeam angleTotal internal reflection
A rotating compensator spectroscopic ellipsometer or polarimeter system having a source of a polychromatic beam of electromagnetic radiation, a polarizer, a stage for supporting a material system, an analyzer, a dispersive optics and a detector system which comprises a multiplicity of detector elements, the system being functionally present in an environmental control chamber and therefore suitable for application in wide spectral range, (for example, 130-1700 nm). Preferred compensator design involves a substantially achromatic multiple element compensator systems wherein multiple total internal reflections enter retardance into an entered beam of electromagnetic radiation, and the elements thereof are oriented to minimize changes in the net retardance vs. the input beam angle resulting from changes in the position and / or rotation of the system of elements.
Owner:J A WOOLLAM CO
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