695results about How to "High thermodynamic stability" patented technology

Trifurcate RNA junction domains derived from phi29 pRNA are described that assemble with high affinity and that are stable in vitro and in vivo. Further expansion of trifurcated RNA domains to multiple way junction scaffolds via creative designs enable an array of toolkit to construct nanoparticle architectures with diverse shapes and angles. The scaffolds can be used to form RNA nanoparticles having a wide variety of uses, including promotion of RNA crystallization, creation of RNA aptamer with high affinity to mimic antibody, delivery of therapeutic and / or diagnostic agents such as biologically active RNA-based moieties, including siRNA, ribozymes, aptamers, and others.

The present invention provides a powdered lithium transition metal oxide useful as a major component for cathode active material of rechargeable lithium batteries, comprising a lithium transition metal oxide particle, a doped interface layer formed near the surface of the particle, and a thermodynamically and mechanically stable outer layer, and a method of preparing the same.

The invention relates to a melamine modified polyvinyl formal foam material and a preparation method thereof. The foam material is prepared by proportionally mixing and reacting among polyvinyl alcohol, melamine, formaldehyde, an acidic catalyst, a basic catalyst, an emulsifier, a foaming agent, a pore former, an adjuvant and the like. The foam material has the advantages of simple preparation process, adjustable aperture ratio, high mechanical strength and good temperature resistance, and can be widely used as medical sponge, filtering material, sound insulation protection material, wiping and dedusting material and biological carrier material.

Methods of making a ternary oxide and a perovskite-related ternary oxide structure are described. The methods include reacting a binary oxide with a metal oxide or a metal hydroxide to form a ternary oxide dielectric layer on a substrate. Powders, anodes, pressed articles, and capacitors including the ternary oxide or perovskite-related ternary oxide structure as a dielectric layer or other layers are further described.

The present invention relates to novel polymorphic and amorphous forms of a phosphate salt of 8-fluoro-2-{4-[(methylamino)methyl]phenyl}-1,3,4,5-tetrahydro-6H-azepino[5,4,3-cd]indol-6-one, and to processes for their preparation. Such polymorphic forms may be a component of a pharmaceutical composition and may be used to treat a mammalian disease condition mediated by poly(ADP-ribose) polymerase activity including the disease condition such as cancer.

The invention discloses a corrosion and abrasion resistant coating and a coating method thereof, comprising: firstly, weight percentage of compositions of coating materials adopted is that: carbon: less than or equal to 0.5 percent; chromium: 16 to 26 percent; nickel: 3.5 to 9.5 percent; molybdenum: 1.0 to 4.0 percent; boron: 0.5 to 4.5 percent; silicon: 0.5 to 4.5 percent; copper: 1.0 to 4.0 percent; manganese: 0 to 2.0 percent; rare earth - rhenium: 0.01 to 1.5 percent; the residual is ferrum and inevitable impurities; secondly, pretreatment of the surface of a metallic matrix reaches technological demand; thirdly, thermal spraying is adopted on the matrix surface; a plurality of air cooling nozzles surrounding a spray gun which are in parallel with spraying flame velocity are arranged on the spray gun; travel rate of the spray gun is 150 to 400 millimeters per second; surface temperature of workpieces is controlled to be less than 150 DEG C; an amorphous stainless steel protective coating is formed on the matrix surface finally; fourthly, sundries on the coating surface are cleaned, and the coating is performed sealing treatment. The invention solves the protective problem of erosion-corrosion under the condition of acid humid environment and that Cl<-> ions and dust particles exist.

The invention discloses a nano-emulsion medicine for treating foot rot. The grain diameter of the nano-emulsion is in a range of 1-100 nanometers and the nano-emulsion is composed of the following raw materials: 0.1-10.0% of pine tar, 0.1-6.0% of cinnamyl aldehyde, 0.1-6.0% of carvacrol, 0.1-5.0% of camphor oil, 0.01-0.1% of clobetasol propionate, 18.0-35.0% of surfactant, 0-7.0% of co-surfactant and residual amount of distilled water; and the sum of the mass percentages of the components is 100%. The nano-emulsion disclosed by the invention has the functions of dissolving cutin, relieving itching, diminishing inflammation, restraining, partially disinfecting and resisting corrosion, accelerating absorption and the like, and is mainly used for treating animal foot rot. According to the nano-emulsion medicine for treating the foot rot, the solubility of the medicine is increased, the medicinal stability and the biological utilization rate are improved, the dosage of the medicine is reduced, the skin transmission rate is higher than that of common preparations including a medicinal extract and the like, and the cost is low, so that the nano-emulsion medicine has a wide market prospect in a veterinary medicine field.

A catalyst for preparing cyclohexene from benzene by hydrogenating is prepared from metal Ru, one or two transition metals or RE elements, the hydroxide of alkali metal as precipitator, and hydrophilic indifferent oxide. It has high activity and selectivity.

A fibrillation-resistant insulin analogue may be a single-chain insulin analogue or a physiologically acceptable salt thereof, containing an insulin A chain sequence or an analogue thereof and an insulin B chain sequence or an analogue thereof connected by a polypeptide of 4-10 amino acids. The fibrillation-resistant insulin analogue preferably displays less than 1 percent fibrillation with incubation at 37° C. for at least 21 days. A single-chain insulin analogue displays greater in vitro insulin receptor binding than normal insulin while displaying less than or equal binding to IGFR than normal insulin. The fibrillation-resistant insulin may be used to treat a patient using an implantable or external insulin pump, due to its greater fibrillation resistance.

The invention relates to lutein ester or lutein emulsion and a preparation method of the lutein ester or lutein emulsion, and aims at solving the problems that the stability and the water solubility of the lutein ester or lutein are poor, and the bioavailability is low. The emulsion is composed of the lutein ester or lutein, a solvent, an emulsifying agent, an auxiliary emulsifying agent, water and the like. The transparent or semi-transparent O / W type lutein ester emulsion is prepared by adopting a micro-emulsifying technology. The method is easy to operate and low in energy consumption, and is suitable for industrial production. The prepared lutein ester emulsion is uniform and has the strong stability, and can be diluted by adding the water at any ratio; and meanwhile, the system compatibility is good, and a plurality of beneficial components including amino acids, minerals, probiotics and the like can be compounded. The lutein ester or lutein emulsion can be widely applied to industries including health products, functional beverages, cosmetics, medicines and the like.

The invention discloses a solid-state battery and a preparation method and application thereof. The solid-state battery comprises a positive plate, a solid-state sulfide electrolyte layer and a negative plate. The positive plate comprises a positive composite material, a solid-state sulfide electrolyte and a conductive agent, the positive composite material comprises a positive material and an LATP coating layer formed on the surface of the positive material, and the solid sulfide electrolyte layer is arranged between the positive plate and the negative plate, wherein the LATP coating layer isobtained by taking the residual lithium salt on the surface of the positive electrode material as a guiding agent and the lithium source and inducing the lithium source, an aluminum source, a titanium source and a phosphorus source through an in-situ synthesis method. The solid-state battery has better rate capability and cycle performance at room temperature and a high temperature (70 DEG C).

The invention discloses a method for preparing a titanium-based nano composite material based on selective laser melting 3D printing, relates to a method for preparing the titanium-based nano composite material, and aims at solving the problem of poor cutting processing performance of titanium and the titanium-based composite material. The method comprises the steps that preparation is conducted,wherein composite powder is prepared through ball milling, and the content of B4C powder in the composite powder is (0.5-1) wt%; selective laser melting 3D printing is utilized for shaping. The methodhas the advantages that the mass of the prepared composite material is light, the thermodynamic stability is high, the strength is high, the wearing resistance is high, fixture tools or molds are notneeded in the shaping process, 'near net shape forming' is easily achieved, the composite material can be massively prepared in a short time, and sources of raw materials are wide; substrate crystalline grains of the prepared composite material are significantly fined, in-site generated complete nano scale TiB whiskers are diffusely distributed on boarders of substrate crystalline grains, an obvious enhancing effect on the composite material is achieved, the mechanical performance is significantly improved, and the method is suitable for preparing the titanium-based nano composite material through 3D printing.

The invention discloses an ivermectin nanoemulsion drug combination. Oil-in-water type nanoemulsion consisting of ethyl oleate, Tween-80, 1,2- propylene glycol and ivermectin is prepared from being diluted by double distilled water. The ivermectin nanoemulsion drug combination greatly improves the effect of ivermectin in resisting parazoon, enhances the dissolubility, safety and bioavailability and is a high-efficiency antiparasitic nano level medicinal preparation with convenient use and wide ways of administration.

A method for selectively orienting molecules on a surface of a solid support. The method includes the steps of: (a) attaching a linker molecule to the surface of the solid support, the linker molecule including a head group that is capable of binding to the solid support, and a tail group that is capable of chelating to a metal ion; (b) subsequently treating the solid support with a solution containing the metal ion; (c) attaching a metal ion chelating tag to the molecules to form tagged molecules; and (d) capturing the tagged molecules on the solid support by contacting it with the tagged molecules to form a monolayer of molecules on the surface of the solid support in which a majority of the molecules are held in the same orientation with respect to the surface. The invention also provides a sensor chip formed using the methods of the invention.

The invention relates to a high-temperature resistant anti-corrosion modified epoxy organic silicon coating and a preparation method. The coating uses organic phosphate and fluoropolymer to modify epoxy organic silicon resin which originally has excellent high-temperature resistant and anti-corrosion properties; with organic phosphate group introduced, not only the high-temperature resistance of resin is improved, but also the later anticorrosion property of the coating can be improved to certain extent. In the film forming process of the coating, the organic phosphate group and substrate metal form a compact phosphate protective film, thus passivating metal surface, preventing water molecules and salt ions from being contacted with metal and further leading the coating to have excellent anticorrosion function. With the fluoropolymer with high-temperature resistance and chemical corrosion resistance introduced, the polymerization between the fluoropolymer and active organic silicon group can distinctly improve the high-temperature resistance of resin. The matched use of the modified epoxy organic silicon resin and a high-temperature resistant pigment can lead the coating to not only maintain proper physical mechanical property, but also have excellent anticorrosion performance under the high temperature condition of 350 DEG C.