18940 results about "Cross linker" patented technology

The disclosure relates to biocompatible components useful for forming compositions for use as medical / surgical synthetic adhesives and sealants. Biocompatible components of the present disclosure may include a multifunctional amine or multifunctional polyol core, with isocyanate and / or polyalkylene oxide arms, which may optionally be capped with electrophilic or nucleophilic groups. These biocompatible components may, in embodiments, be combined with optional cross linkers to form adhesive and / or sealant compositions.

Disclosed is a method of making conjugates of cell binding agents and small molecule drugs comprising reacting a cell binding agent with a bifunctional cross-linking moiety to thereby provide the cell binding agent with a reactive disulfide group and then reacting the modified cell binding agent with a small molecule drug comprising a free thiol group. Bifunctional cross-linking moieties are also disclosed.

Charged or pro-charged cross-linking moieties and conjugates of cell binding agents and drugs comprising the charged or pro-charged cross-linking moieties and method of making the same.

The present invention relates to a cross-linker for photoresist compositions which is suitable for a photolithography process using KrF (248 mn), ArF (193 mn), E-beam, ion beam or EUV light sources. Preferred cross-linkers, according to the present invention, comprise a copolymer of (i) a compound represented by following Chemical Formula 1 and / or (ii) one or more compound(s) selected from the group consisting of acrylic acid, methacrylic acid and maleic anhydride. ##STR1## wherein, R.sub.1 and R.sub.2 individually represent straight or branched C.sub.1-10 alkyl, straight or branched C.sub.1-10 ester, straight or branched C.sub.1-10 ketone, straight or branched C.sub.1-10 carboxylic acid, straight or branched C.sub.1-10 acetal, straight or branched C.sub.1-10 alkyl including at least one hydroxyl group, straight or branched C.sub.1-10 ester including at least one hydroxyl group, straight or branched C.sub.1-10 ketone including at least one hydroxyl group, straight or branched C.sub.1-10 carboxylic acid including at least one hydroxyl group, and straight or branched C.sub.1-10 acetal including at least one hydroxyl group; and R.sub.3 represents hydrogen or methyl.

The invention relates to novel crosslinkable copolymers which are obtainable by (a) copolymerizing at least two different hydrophilic monomers selected from the group consisting of N,N-dimethyl acrylamide (DMA), 2-hydroxyethyl acrylate (HEA), glycidyl methacrylate (GMA), N-vinylpyrrolidone (NVP), acrylic acid (AA) and a C1-C4-alkoxy polyethylene glycol (meth)acrylate having a weight average molecular weight of from 200 to 1500, and at least one crosslinker comprising two or more ethylenically unsaturated double bonds in the presence of a chain transfer agent having a functional group; and (b) reacting one or more functional groups of the resulting copolymer with an organic compound having an ethylenically unsaturated group.

There is provided: a production process for a water-absorbing agent having stable properties in a short time; and a water-absorbing agent. The production process comprises the step of blending an acid-group-containing water-absorbent resin powder with a noncrosslinkable water-soluble inorganic base and / or an irreducible alkaline-metal-salt pH buffer and further with a dehydratable crosslinking agent reactable with the acid group, thereby subjecting the resin powder to crosslinking treatment, or comprises the step of blending an acid-group-containing water-absorbent resin powder with the above base and / or pH buffer and further with a crosslinking agent reactable with the acid group, thereby subjecting the resin powder to crosslinking treatment, wherein the resin powder has a weight-average particle diameter of 300 to 600 mum wherein the ratio of fine powders having particle diameters of not larger than 150 mum in the resin powder is not more than 10 weight %.

An improved cellular plastic material comprises a urethane foam that is the reaction product of soy oil, an isocyanate, and a cross linker. The soy oil replaces the polyol typically generally required in the production of urethanes. Because the replaced polyol is a petrochemical, use of a renewable and environmentally friendly material such as soy oil is most advantageous. Further, plastic materials of many final qualities may be formed using a single vegetable oil. In addition to cellular foams, solid plastic elastomers may be formed.

An vivo biocompatible and bio-excretable lubricant and ultrasound coupling fluid or gel comprising polyvinylpyrrolidone (PVP) and / or polyvinyl alcohol (PVA). The inventive couplant fluid or gel comprises polyvinylpyrrolidone and / or polyvinyl alcohol solutions in water to which humectants such as alkylene glycols and / or polyalkylene glycols are added to achieve desired tactile and drying characteristics. Additionally, such fluids and gels may be prepared by addition of organic and inorganic cross-linkers.

A process for the crosslinking of at least one polymer selected from polysaccharides and derivatives thereof, which is carried out in an aqueous solvent by the action of an effective and non-excessive amount of at least one crosslinking agent, characterized in that it is carried out on a mixture containing at least one low-molecular weight polymer and at least one high-molecular weight polymer. A process for the preparation of an injectable monophase hydrogel of at least one crosslinked polymer selected from polysaccharides and derivatives thereof is also disclosed. Crosslinked polymers and injectable monophase hydrogels, respectively, are obtainable by each of said processes.

The invention relates to a coating composition on the surface of a filtration media. In particular, the invention relates to a coating composition for a filtration media comprising at least one polymer; at least one crosslinking agent; and optionally at least one compatabilizing agent.

A formaldehyde-free curable aqueous composition containing polyvinyl alcohol, a multi-functional crosslinking agent, and, optionally, a catalyst. The composition may be used as a binder for non-woven products such as fiberglass insulation. The non-woven products are formed by contacting the formaldehyde-free curable aqueous composition with fibrous components and the mixture is cured to form a rigid thermoset polymer providing excellent strength and water resistance of the cured nonwoven product.

An undercoat-forming material comprising a novolak resin having a fluorene or tetrahydrospirobiindene structure, an organic solvent, an acid generator, and a crosslinker, optionally combined with an intermediate layer having an antireflective effect, has an absorptivity coefficient sufficient to provide an antireflective effect at a thickness of at least 200 nm and a high etching resistance as demonstrated by slow etching rates with CF4 / CHF3 and Cl2 / BCl3 gases for substrate processing.

A mixture of crosslinkable liquid-crystalline substances having a chiral phase (LC mixture), containing polymerizable groups, where at least 90% of the polymerizable groups are part of molecules containing at least two polymerizable groups (crosslinker molecules), wherein from 3.2 to 15 mmol of polymerizable groups are present per g of LC mixture. The crosslinked pigments show little color shift in the presence of solvents or upon application to substrate different temperatures.

The invention provide a class of chain-extended polysiloxane crosslinkers which comprises (1) at least two polysiloxane segments, wherein each pair of adjacent polysiloxane segments is linked by one divalent organic radical which includes at least one pendant hydrophilic group (hydroxyl and / or carboxyl groups) or at least one dangling hydrophilic polymer chain and a di-thioether linkage —S-DR-S— in which DR is a divalent organic radical; and (2) two terminal ethylenically unsaturated groups. The present invention is also related to a polymer comprising crosslinking units derived from chain-extended polysiloxane crosslinker of the invention and to ophthalmic lenses comprising such a polymer.

A coating composition is provided comprising: (i) a fluorinated polymer comprising (a) structural units having the formula (I):—CR1R2—CFX—  (I)wherein R1 and R2 are each independently an alkyl group, a fluorine atom, a chlorine atom, a hydrogen atom or a trifluoromethyl group, and X is a fluorine atom, a chlorine atom, a hydrogen atom or a trifluoromethyl group, and (b) structural units comprising at least one type of crosslinkable functional group; (ii) a crosslinking agent; and (iii) a plurality of particles functionalized with a functional group, wherein the functional group on the particles is essentially non-reactive with the fluorinated polymer and with the crosslinking agent. Articles comprising a coating composition described in embodiments of the invention are also provided.

A method for labeling acyl carrier protein (ACP) fusion proteins with a wide variety of different labels is disclosed. The method relies on the transfer of a label from a coenzyme A type substrate to an ACP fusion protein using a holo-acyl carrier protein synthase (ACPS) or a homologue thereof. The method allows detecting and manipulating the fusion protein, both in vitro and in vivo, by attaching molecules to the fusion proteins that introduce a new physical or chemical property to the fusion protein. Examples of such labels are, among others, spectroscopic probes or reporter molecules, affinity tags, molecules generating reactive radicals, cross-linkers, ligands mediating protein-protein interactions or molecules suitable for the immobilization of the fusion protein.

Charged or pro-charged cross-linking moieties and conjugates of cell binding agents and drugs comprising the charged or pro-charged cross-linking moieties and method of making the same.

A mixture is provided comprising (a) at least one of an elastomeric thermoplastic, a non-elastomeric thermoplastic, an elastomeric thermoset and mixtures thereof, excluding polydiorganosiloxane fluids and (b) a polymer having soft polydiorganosiloxane units, hard polyisocyanate residue units, optionally, soft and / or hard organic polyamine residue units and terminal groups. The hard polyisocyanate residue and the hard polyamine residue comprise less than 50% by weight of the polydiorganosiloxane urea containing component. The polyisocyanate residue is the polyisocyanate minus the —NCO groups and the polyamine residue is the polyamine minus the —NH2 groups. The polyisocyanate residue is connected to the polyamine residue by urea linkages. The terminal groups are non-functional groups or functional groups. The polydiorganosiloxane urea containing component may be reactive under free-radical or moisture curing conditions. The mixture may also optionally contain tackifying materials, free radical initiators, crosslinking agents, cure catalysts, and nonreactive additives such as fillers, pigments, stabilizers, antioxidants, flame retardants, plasticizers, compatibilizers and the like.

The invention belongs to the technical field of a new chemical material, and in particular relates to a high-durability super-hydrophobic self-cleaning coating material and a preparation method thereof. The coating material of the invention is prepared by curing and drying nanoparticles with photo-catalytic activity, a low-surface-free-energy polymer and a cross-linking agent at the room temperature, wherein the low-surface-free-energy polymer consists of one or more of polysiloxane fluoride, dimethyl silicone polymer and polyphenylene methyl siloxane, which contain active groups, such as hydroxyl alkoxy group, carbon-carbon double bond, silanol group, siloxy group, and the like; the cross-linking agent is hydrogen-containing silicone oil or aminosilane; and the mass content of the photo-catalytic nanoparticles in the coating ranges from 10 to 60 percent. The coating is formed into a micro-nanostructure by nanoparticle self-organization; a super-hydrophobic self-cleaning coating with lotus effect is prepared from the coating and a cross-linked filming matrix with low surface energy; the persistence of a lotus-shaped super-hydrophobic characteristic of the coating is realized by using the photo-catalytic decomposition characteristic of an organic pollutant for the nanoparticles; and thus the material is suitable for large-area construction and has high weathering resistance andprominent self-cleaning characteristic.

The present specification generally relates to multifunctional polyethylene glycol-based crosslinking agents, hydrogel compositions comprising a matrix polymer crosslinked with such crosslinking agents, and methods of treating a soft tissue condition using such hydrogel compositions.

Disclosed are Bisphenol A (BPA), Bisphenol F, Bisphenol A diglycidyl ether (BADGE), and Bisphenol F diglycidyl ether (BFDGE)-free coating compositions for metal substrates including an under-coat composition containing a polyester (co)polymer, and an under-coat cross-linker; and an over-coat composition containing a poly(vinyl chloride) (co)polymer dispersed in a substantially nonaqueous carrier liquid, an over-coat cross-linker, and a functional (meth)acrylic (co)polymer. Also provided is a method of coating a metal substrate using the BPA, BPF, BADGE and BFDGE-free coating system to produce a hardened protective coating useful in fabricating metal storage containers. The coated substrate is particularly useful in fabricating multi-part foodstuffs storage containers with “easy-open” end closures.

The invention provide a class of chain-extended polysiloxane crosslinkers which comprises (1) at least two polysiloxane segments, wherein each pair of adjacent polysiloxane segments is linked by one divalent organic radical which includes at least one pendant hydrophilic group (hydroxyl and / or carboxyl groups) or at least one dangling hydrophilic polymer chain and a di-thioether linkage —S-DR—S— in which DR is a divalent organic radical; and (2) two terminal ethylenically unsaturated groups. The present invention is also related to a polymer comprising crosslinking units derived from chain-extended polysiloxane crosslinker of the invention and to ophthalmic lenses comprising such a polymer.

A composition used to form an acid sensitive +E,uns a+EE nti+E,uns r+EE eflective +E,uns c+EE oating (ARC) includes a water soluble resin and a cross-linker. Radiation adsorptive components may be provided as part of the resin or, more preferably, as a separate dye. The composition may be applied on a substrate as a radiation adsorbing layer and additionally cross-linked to form an acid sensitive, water insoluble ARC on which a +E,uns p+EE hoto+E,uns p+EE atterning +E,uns r+EE esist (PPR) layer may be formed. Being acid sensitive, selected portions of an ARC formed from the composition may be removed by a suitable reversal of the cross-linking followed by a develop step, preferably with an aqueous developer, more preferably de-ionized water. The water soluble resin is preferably hydroxystyrene-sulfonated styrene copolymer, poly(2-isopropenyl-2-oxazoline), or poly(acrylic acid), the cross-linker is preferably an acetal diacid or a water soluble divinyl ether, and the dye is preferably 9-anthracene methanol or a squaric acid derivative. If a suitable +E,uns p+EE hoto+E,uns a+EE cid +E,uns g+EE enerator (PAG) is included then an ARC formed from such components may exhibit a photosensitivity similar to or even lower than that of the overlying PPR. The photosensitivity is preferably less than about 900 mJ / cm2, more preferably 100 mJ / cm2 or less.

The invention discloses a composite natural polymer gel material with a cross-linking agent. The material comprises hydrogel, organogel, aerogel and bioplastics and mainly overcomes the problem of low mechanical strength of conventional natural polymer gel materials. According to the invention, a certain amount of the cross-linking agent is added into a natural polymer water-based solution or dispersion liquid, then stirring is carried out, the obtained mixture is placed in a non-solvent for physical cross-linking, and then washing is carried out so as to obtain composite natural polymer hydrogel; water in the composite natural polymer hydrogel is replaced with an organic solution so as to prepare composite natural polymer organogel; the composite natural polymer hydrogel or organogel is dried so as to prepare composite natural polymer aerogel; the composite natural polymer aerogel is subjected to hydrophobic treatment so as to obtain hydrophobic aerogel; the composite natural polymer aerogel is subjected to heat treatment so as to obtain carbon aerogel; and one or more selected from the above-mentioned gel materials are subjected to high-temperature pressing so as to prepare composite natural polymer bioplastics. The composite natural polymer gel material prepared in the invention has the advantages of excellent mechanical properties, a high specific surface area, high elongation at break, etc., and can be easily processed into molded products of a plurality of forms.

A formaldehyde-free curable aqueous composition comprising an adduct of (a) carbohydrate polymer and (b) a multi-functional crosslinking agent such as a polybasic acid may be used as a binder for non-woven products such as fiberglass insulation.

A hydrogel polymer obtained by polymerizing a monomer component including acrylic acid (salt) is post-neutralized so that each of polymer particles derived from a polymer produced by neutralizing the hydrogel polymer has an allowable neutralization ratio. The polymer as obtained by neutralizing the hydrogel polymer is reacted with a crosslinking agent reactive to a functional group of the polymer. The allowable neutralization ratio, for example, is a neutralization ratio which is not lower, by not less than 20 mole percent, or more than, at least 55 mole percent, than an average neutralization ratio of a mass of the polymer particles, and the post-neutralization is carried out so that a number of polymer particles having a non-allowable neutralization ratio outside the allowable neutralization range is not more than 10 in 200 polymer particles, thus obtaining a water-absorbent agent having high absorbency under no applied pressure and high pressure wherein the amount of water soluble component is lower compared with the conventional water-absorbent agent and a change in pH of a swollen gel is small.

A method for improving the storage stability of personal care formulations containing ultraviolet (UV) radiation-absorbing agents (sunscreen agents) is disclosed. Latex polymer particles containing a void, having a particle size from 50 to 1000 nanometers, and having at least 4% polymerized crosslinker monomer units in the shell portion of the particle are especially effective in maintaining storage stability and effectiveness of sunscreen formulations when added to personal care compositions containing at least one sunscreen agent.

The present invention relates to thickened fabric conditioners, which fabric conditioners contain a particular polymeric thickener, which is obtained by polymerizing from 5 to 100 mole percent of a cationic vinyl addition monomer, from 0 to 95 mole percent of acrylamide, and from 70 to 300 ppm of a difunctional vinyl addition monomer cross-linking agent. As compared to such compositions comprising a similar product but obtained from a polymerization reaction using between 5 and 45 ppm cross-linking agent considerable advantages are obtained. Especially, the delivery of fragrance present in the softening composition is more efficiently carried over to the fabrics to be treated.