1588 results about "Nebulizer" patented technology

Improved devices, systems, and methods for inhibiting hyperplasia in blood vessels provide controlled and safe cryotherapy treatment of a target portion within a body lumen of a patient. Efficacy of endoluminal cryogenic cooling can be enhanced by limiting cooling of target tissues using a thermal barrier disposed between a dual balloon cryotherapy catheter. Containment of both balloons can be monitored by applying a vacuum within a space between the first and second balloons, and by coupling the vacuum space to a fluid shutoff so as to inhibit flow of cryogenic fluid in response to a change in the vacuum space. Controlled cooling of the vessel can be improved by use of a nebulizer in fluid communication with a cryogenic liquid supply lumen and a gas supply lumen.

An inhalable unit dose liquid formulation containing SAE-CD and corticosteroid is provided. The formulation is adapted for administration to a subject by nebulization with any known nebulizer. The formulation can be included in a kit. The formulation is administered as an aqueous solution or concentrated composition. The formulation is employed in an improved nebulization system for administering corticosteroid by inhalation. SAE-CD present in the formulation significantly enhances the chemical stability of corticosteroid, such as budesonide. A method of administering the formulation by inhalation is provided. The formulation can also be administered by conventional nasal delivery apparatus. The formulation is prepared by mixing SAE-CD, in solid or liquid (dissolved) form, with an inhalable suspension-based unit dose formulation.

The present disclosure relates to atomizers for an aerosol delivery device such as a smoking article. The atomizer may include a liquid transport element and a wire extending along at least a portion of a longitudinal length thereof. The wire may define contact portions configured to engage heater terminals and a heating portion configured to produce heat. The heating portion may include a variable coil spacing. In other atomizers, the wire may extend at least partially through the liquid transport element proximate the contact portions. Related inputs, cartridges, aerosol production assemblies, and methods of forming atomizers are also provided.

The invention relates to a medical instrument used for drug absorption of pulmonary alveoli, in particular to an intrapulmonary drug administration device atomizing drugs dissolved in liquid into fine particles reaching the pulmonary alveoli, which comprises a casing and a suction nozzle arranged at one side of the casing. The invention is characterized in that a battery, a liquid supplying bottle and an atomizer are arranged in the casing, wherein, one end of the liquid supplying bottle is communicated with the suction nozzle, while the other end is connected with the atomizer, an air inlet is arranged on the casing above the atomizer, and an air passage is arranged on the outer surface of the liquid supplying bottle; an action switch is arranged on the casing. The invention has the advantages that the drug can be atomized into uniform particles, the particles are small, and the average diameter can reach about 1 micron, which is the best technical parameter for intrapulmonary absorption; a quantitative device arranged in the invention can control the drug administration amount; the invention can be used for drug administration of bronchioles and pulmonary alveoli.

A pneumatic nebulizer that produces a high volume of aerosols for inhalent delivery of medications and other constituencies. High pressure gas formed into a gas jet is passed through a thin choked region of fluid that is entrailed and impinged upon an aerosol amplifier which creates a spray whose aerosol components are directed up through vents to an aerosol outlet for delivery. Larger-sized liquid particles are caused to pool up in a region surrounding the aerosol amplifer and then drip down back into the liquid medication reservoir.

An exhalation breath-actuated nasal delivery device for and a method of delivering a substance to a nasal cavity of a subject, the delivery device comprising: a nosepiece (40) for fitting to a nostril of a subject; a mouthpiece (42) through which the subject in use exhales; and delivery unit (64), as one of a mechanical delivery pump (66) or a nebulizer (115), for delivering a substance to the nosepiece (40); and an actuation mechanism (74) for actuating the delivery unit in response to oral exhalation through the mouthpiece, and preferably when at least one or both of the pressure at or the flow rate through the nosepiece exceeds a predetermined threshold.

An atomizer for an inhaler includes a housing, a gasket, a liquid absorbing sheet, a wick, and an atomizing element. The housing includes a first housing and a second housing, the first housing and the second housing form a liquid reservoir therebetween for storing liquid. The gasket is sleeved on the first housing, the gasket defines a liquid conducting hole in communication with the liquid reservoir. The liquid absorbing sheet is sleeved on the first housing in contact with the gasket, the liquid absorbing sheet is configured to absorb the liquid in the liquid reservoir via the liquid conducting hole. The wick is in contact with the liquid absorbing sheet and configured to draw the liquid from the liquid absorbing sheet. The atomizing element is fixed to the wick and configured to atomize the liquid in the wick.

A nebulizer for efficiently and reliably delivering aerosolized fluid to an inhaling patient is disclosed. The nebulizer includes a fluid channel air inlet and fluid channel air inlet valve responsive to either a manual force external of the nebulizer, or a patient's breathing, to begin the nebulization process. Also provided is a method of providing nebulization including the steps of moving a fluid channel air inlet valve against a fluid channel air inlet so that a negative pressure may build up over the fluid in the fluid channel to draw fluid from the fluid reservoir and begin nebulization during inhalation.

The invention relates to a two-stage pressure atomizer nozzle with a nozzle body (30) having a mixing chamber (39) which is connected to an outside space via a nozzle outlet bore (33), and with a first feed duct (42) with a feed bore (41) for a liquid (37) to be atomized, through which feed bore said liquid (37) can be fed, free of swirling and under pressure, at least one further feed duct (36) for a portion of the liquid (37) to be atomized or for a second liquid (37') to be atomized opening into the chamber (39), through which feed duct said liquid (37, 37') can be fed under pressure and with swirling. The feed bore (41) of the first feed duct (42) lies on one axis (34) with the nozzle outlet bore (33). It is defined in that the outlet-side diameter (da) of the nozzle outlet bore (33) is at most as large as the diameter (dz) of the feed bore (41) and the length (L) of the nozzle outlet bore (33) is at least twice to at most ten times the outlet-side diameter (da) of the nozzle outlet bore (33).

A nebulizer for efficiently and reliably delivering aerosolized fluid to an inhaling patient is disclosed. The nebulizer includes a fixed diverter and a movable fluid orifice or fluid pathway connected with an actuator for responding to an inhalation or a manual actuation and beginning the nebulization process. Also provided is a method of providing nebulization including the steps of moving a fluid orifice or fluid pathway connected to an actuator so that the fluid orifice or fluid pathway reaches a nebulizing position during inhalation.

A pharmaceutical delivery system for oral inhalation is disclosed through nebulization consisting of an inert supporting material impregnated with or deposited with pharmaceutically active ingredient which must be solubilized or suspended in a pharmaceutical solvent to form a solution or suspension prior to administration. Each pharmaceutical delivery unit dosage form comprises one or more therapeutically effective and safe amounts of pharmaceutically active ingredient uniformly impregnated in or deposited on a supporting material which is a natural or synthetic polymer, woven or non-woven fabrics, inert paper, inorganic materials such as foil and combination thereof in a single or multi-layer lamination in a form of a sheet or strip or film or membrane or sponge-like or cup or well. The dosage form of this invention is to be administered to a patient through oral or nasal inhalation using a nebulizer after reconstitution with a reconstituting solvent.

An atomizer is disclosed. The atomizer of the present invention comprises a main unit, a pipe, and a vaporizer. The vaporizer of the present invention comprises a pneumatic switch which is triggered by the airflow from the main unit. There is no conducting wire between the main unit and the vaporizer. The length of the pipe is determined according to the requirement of the user. In one embodiment of the present invention, the atomizer is remote controllable.

An atomizing nebulizer for dispensing a substance or medicament is described. The nebulizer is formed with a reservoir base releasably secured to an effluent vent cap that together capture a diffuser and integral dispersing baffle that are further formed with an uptake lumen or channel terminating with a nozzle jet. The diffuser dispersing baffle is positioned relative to the jet nozzle to optimize atomization of any of a number of such substances so as to maximize disbursement of the substance. The reservoir base also incorporates a pressurized fluid-accelerating inlet tube terminated with a metering orifice that cooperates with the nozzle jet when the inlet tube is received within the diffuser uptake lumen or channel. When so received, the nozzle jet axially registers proximate and superior to the orifice to establish a vacuum space that is in fluid communication with a capillary interstice established between the walls of the exterior of the inlet tube and the confronting interior surface of the diffuser lumen or channel. When a pressurized fluid is communicated through the lumen, the orifice, and into the vacuum space towards the nozzle jet, a vacuum develops in the vacuum space that, in combination with the capillary action of the interstice, draws the fluid proximate to the orifice and disperses it into droplets that are then entrained into a fluid stream to be further atomized upon impact with the baffle and then dispensed.