Red flavonid and production process of its medicine composition
A technology for total red flavonoids and medicines, which is applied in the field of medicine, can solve the problems such as few production process researches, and achieves the effects of stable preparation, stable process and low process cost.
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Embodiment 1
[0027] 540 grams of a little red, add appropriate amount of water (about 980 grams), heat and boil for about 1.5 hours, filter out the liquid medicine, add appropriate amount of water to the medicine dregs, heat and boil for about 1.5 hours, combine the two filtrates, concentrate to a clear paste (50 ℃ heat test When the relative density is 1.10 ~ 1.15).
[0028] Take an appropriate amount of the above-mentioned clear ointment, add water to dissolve, add dilute sulfuric acid to heat and reflux for hydrolysis, let it cool, and extract it with ethyl acetate as the test sample. main ingredient.
Embodiment 2
[0030] 10 kg of a little red, 7.5 kg of goldenrod, 0.63 kg of ginger, and 6.25 kg of Radix Banlangen, take a little red, goldenrod and ginger, put them in an extractor, add water and boil twice, each time for 1.5 hours, combine the decoction, and let it stand. Concentrate the supernatant into a clear paste. Take another Radix Radix, add water and decoct twice, each time for 1.5 hours, combine the decoction, filter, and concentrate the filtrate into a clear paste (relative density when measured at 50°C is 1.10-1.15), add ethanol to make the alcohol content reach 60% , stand overnight, filter, and the filtrate is concentrated into a clear paste after recovering ethanol. The clear pastes obtained above were combined and concentrated into a thick paste (the relative density was 1.30-1.40 when thermally measured at 80°C).
Embodiment 3
[0032] The thick paste obtained in Example 2 is heated and stirred according to the concentration ratio of paste: purified water=1: 1.1 (weight ratio), fully dissolved, and passed through an 80-mesh sieve as a binder.
[0033] Take another 3.75 kg of licorice, grind it into a fine powder, and pass through a 100-mesh sieve. Get another 0.45 kg of dextrin. Put the licorice fine powder and dextrin into the granulator, after fully mixing, carry out one-step granulation with the above-mentioned prepared binder as the spray liquid and take it out after drying for 30 minutes, after the moisture content is determined to be qualified (moisture content 3-7 %) to obtain dry particles.
[0034] Add magnesium stearate according to 5 / 1000 of the weight of the dry granules, mix well, and then compress into tablets to make 10,000 tablets.
[0035] The prescription composition of the present invention belongs to clinical experience prescription, and curative effect is definite and stable. T...
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