The invention aims to provide a traditional Chinese medicine extract with heat-clearing, detoxifying, antibacterial and anti-inflammatory functions. The traditional Chinese medicine extract with the heat-clearing, detoxifying, antibacterial and anti-inflammatory functions is prepared by extracting the following medicine raw materials of radix scutellariae, dandelion, herba corydalis bungeanae and isatis root through a scientific and reasonable process method, wherein the mass ratio of radix scutellariae to dandelion to herba corydalis bungeanae to isatis root is (1-3): (3-5):(0.5-2):(1-3). The traditional Chinese medicine extract with the heat-clearing, detoxifying, antibacterial and anti-inflammatory functions has the advantages the impurity ingredients in the medicine materials are maximumly removed, the effective ingredients are fully remained, and the heat-clearing, detoxifying, antibacterial and anti-inflammatory effects are realized. The invention also discloses four preparations containing the traditional Chinese medicine extract with the heat-clearing, detoxifying, antibacterial and anti-inflammatory functions, i.e. syrup, mixture, buccal tablet and dripping pill. The four preparations have the advantages that the heat-clearing, detoxifying, antibacterial and anti-inflammatory functions are realized, the preparations can be clinically used for preventing and controlling diseases, such as furuncle, pharyngitis, parotitis, lymphadenitis and tonsillitis, the content of effective ingredients is high, the dosage is small, the preparations are stable, and the therapeutic effect is good. The invention also provides a quality control method of the preparations containing the traditional Chinese medicine extract with the heat-clearing, detoxifying, antibacterial and anti-inflammatory functions.