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Antiviral honeysuckle flower Chinese medicine compound preparation and preparation technique

A compound preparation, honeysuckle technology, applied in antiviral agents, anti-inflammatory agents, pharmaceutical formulations, etc., can solve the problems that drugs are rarely seen and affect work, study and life

Active Publication Date: 2008-10-29
吉林省通化振国药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] At present, most colds are caused by virus infection, known as viral influenza, which is widespread and often occurs throughout the year. If viral influenza cannot be cured in time, it will also cause other diseases. Treatment of viral influenza Although there are many kinds of medicines, the medicines with significant curative effect are rarely seen, thus seriously affecting people's work, study and life.

Method used

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  • Antiviral honeysuckle flower Chinese medicine compound preparation and preparation technique

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0069] Weigh 25 kg of honeysuckle medicinal material, add 12 times the amount of water to decoct and extract twice, each time for 1.0 hour, the extracts are filtered and combined. The water extract was concentrated under reduced pressure to 1 g crude drug / ml (relative density 1.150, 25° C.), and the concentrated solution was added with 92.5 L of 95% ethanol (stirred) to make the alcohol content of the medicinal solution to 75%, and allowed to stand for 24 hours. Recover ethanol from the alcoholic solution to liquid extract, add 25.0L of water to dissolve, centrifugal filter (2000 rpm), the filtrate (1g crude drug / ml, relative density 1.060, 25°C) passes through the treated SP-700 macroporous adsorption resin (50L ), eluted with water of 4 times the volume of the resin column, and discarded. Then elute with 18% ethanol with 5 times the volume of the resin, recover the 18% ethanol eluate under reduced pressure to a concentrated solution (relative density 1.080), freeze-dry, and ...

Embodiment 2

[0076] 1) Dissolve 45 g of the honeysuckle extract prepared in Example 1 in 200 ml of water for injection, after dissolving, add 10% NaOH (0.25M) solution, stir while adding and adjust the pH value between 6.50 and 7.00;

[0077] 2) Add 20 g of licorice extract to 200 ml of water for injection, add 10% NaOH (0.25M) solution, stir while adding, after dissolving, adjust the pH value between 6.50 and 7.00;

[0078] 3) Add 35g of Scutellaria baicalensis extract to 400ml of water for injection, stir while adding, and after fully suspending, add 10% NaOH (0.25M) solution to adjust the pH value until it is completely dissolved. The solution is a yellow-green solution, and the pH value is adjusted to 6.50 ~7.00;

[0079] 4) fully mixing the aqueous solutions of the above three extracts, and controlling the pH value between 6.50 and 7.00;

[0080] 5) After filtering with a 0.45 μm microporous membrane, add water for injection to 1000 ml, in a sterile clean room, filter with an ultrafi...

Embodiment 3

[0082] 1) Dissolve 40 g of the honeysuckle extract prepared in Example 1 in 200 ml of water for injection, after dissolving, add 10% NaOH (0.25M) solution, stir while adding and adjust the pH value between 6.50 and 7.00;

[0083] 2) Add 18 g of licorice extract to 200 ml of water for injection, add 10% NaOH (0.25M) solution, stir while adding, after dissolving, adjust the pH value between 6.50 and 7.00;

[0084] 3) Add 25g of Scutellaria baicalensis extract to 400ml of water for injection, stir while adding, after fully suspending, add 10% NaOH (0.25M) solution to adjust the pH value until it is completely dissolved, the solution is a yellow-green solution, adjust the pH value to 6.50 ~7.00;

[0085] 4) fully mixing the aqueous solutions of the above three extracts, and controlling the pH value between 6.50 and 7.00;

[0086] 5) After filtering with a 0.45 μm microporous membrane, add water for injection to 1000 ml, in a sterile clean room, filter with an ultrafiltration memb...

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Abstract

The invention discloses an anti-virus honeysuckle flower traditional Chinese medicine compound preparation, which is prepared by honeysuckle flower extract, liquoric root extract and baical skullcap root extract; the formula is a pure traditional Chinese medicine preparation and has significant effects of anti-virus, anti-bacterium, eliminating heat, relieving pain, anti-inflammatory and eliminating phlegm and is used for treating the symptoms such as fever, cough, asthma, sore throat, dry mouth and so on caused by exogenous wind-heat and interior stagnancy of toxic heat. The anti-virus honeysuckle flower traditional Chinese medicine compound preparation can also be used for the clinical treatment of upper respiratory tract infection, acute and chronic tonsillitis, pneumonia and laryngitis with the symptoms, the clinical symptoms can disappear rapidly and the efficacy is significant.

Description

technical field [0001] The invention relates to an antiviral traditional Chinese medicine, further provides an antiviral honeysuckle compound traditional Chinese medicine injection preparation, and also discloses its preparation process, which belongs to the technical field of traditional Chinese materia medica. Background technique [0002] At present, most colds are caused by virus infection, known as viral influenza, which is widespread and often occurs throughout the year. If viral influenza cannot be cured in time, it will also cause other diseases. Treatment of viral influenza Although there are many kinds of medicines in China, the medicines with significant curative effect are rarely seen, thus seriously affecting people's work, study and life. Contents of the invention [0003] The invention discloses an antiviral honeysuckle compound traditional Chinese medicine preparation. The main active components of the preparation are fully extracted to prepare the preparat...

Claims

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Application Information

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IPC IPC(8): A61K36/539A61K9/08A61P31/12A61P31/04A61P11/00A61P29/00
Inventor 王振国王振贤
Owner 吉林省通化振国药业有限公司
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