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Compound cordate bouttuynia bolus and its prepn

A technology of Houttuynia cordata and Houttuynia cordata is applied in the directions of pill delivery, pharmaceutical formulations, and medical preparations containing active ingredients, etc., and can solve the problems of easy loss of volatile components, cumbersome coating of sugar-coated tablets, and low quality standards.

Inactive Publication Date: 2004-11-24
毛友昌
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The dosage of the tablet is large, it is difficult to swallow, and the volatile components are easily lost during production, and the coating of the sugar-coated tablet is cumbersome, and the disintegration is slow. At the same time, its quality standard is low and there is no quantitative index

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] Embodiment 1: The five medicines are cleaned respectively, remove impurities, and pass the inspection for subsequent use; take Houttuynia cordata (about 1 / 3 of the prescription amount), forsythia, and honeysuckle, and grind them into fine powder, and the remaining Houttuynia cordata is mixed with Scutellaria baicalensis and Radix Radix Add water and decoct twice for 2 hours each time, combine the decoction, filter, concentrate the filtrate into a thick paste, mix with the above-mentioned fine powder and appropriate amount of auxiliary materials, make pills, dry, and coat.

Embodiment 2

[0035] Example 2: The five medicines were cleaned separately to remove impurities and passed the inspection for later use; extract the volatile oil from Houttuynia cordata, forsythia, and honeysuckle, and encapsulate the volatile oil with an appropriate amount of β-cyclodextrin for later use; decoct the dregs of the medicine with Scutellaria baicalensis and Radix Radix Radix in water Boil twice, 2 hours each time, combine the decoction, filter, concentrate the filtrate to a relative density of 1.08-1.10, spray dry to make a dry cream powder, mix with the above-mentioned volatile oil cyclodextrin inclusion compound and appropriate amount of auxiliary materials, and make Pills, dried, coated, ready to use.

Embodiment 3

[0036] Example 3: Clean the five herbs respectively, remove impurities, and pass the test for later use; add water to the five herbs in the prescription and cook them twice, each time for 2 hours, and collect the volatile oil and cooking liquid for later use; the above-mentioned volatile oil is packaged with an appropriate amount of β-Huanhu essence Combined for use; water cooking liquid combined, filtered, the filtrate concentrated to a relative density of 1.08-1.10, spray-dried to make a dry cream powder, mixed with the above-mentioned volatile oil cyclodextrin inclusion compound and appropriate amount of auxiliary materials, made into pellets, dried, packaged Clothes, get it.

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Abstract

The present invention discloses complex cordate houttuynia bolus and its preparation. The present invention relates to preparation form innovation on the basis of available tablet, and the medicine has the advantages of fast release speed, high bioavailability, less irritation, etc. The medicine has the functions of clearing away heat and toxic material, and is used in treating wind and cold caused throat pain, acute pharyngitis and tonsillitis with high curative effect.

Description

technical field [0001] The invention relates to the technical field of manufacturing technology of Chinese patent medicine pills, in particular to compound Houttuynia cordata pills and a preparation method thereof. Background technique [0002] Pills are a traditional dosage form. Due to the rapid development of modern science and technology, the continuous upgrading of equipment in pharmaceutical institutions, the advent of new pill-making machines and the wide application of new excipients have brought youthful vitality to the ancient dosage form of traditional Chinese medicine pills. It has changed people's traditional prejudice against traditional pills "black, big and thick", and made the pills produced have the advantages of fast drug release, high bioavailability, small irritation, accurate dosage, easy to take and carry; according to In my country's relevant drug laws and regulations, changing the dosage form needs to be studied as a new drug. T...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/20A61K9/36A61P11/04
Inventor 毛友昌毛小敏
Owner 毛友昌
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