The invention provides an externally applied gel for treating
gout, which is an externally applied
medicine made from
traditional Chinese medicine components such as nidus vespae,
colchicine, a
gel matrix, and the like., and by taking a
coupling medium as transdermal carrier. The anti-
gout gel can quickly eliminate redness, swelling, pain and
fever symptoms of
gouty arthritis, inhibit
granulocyte infiltration and formation of
lactic acid, reduce synthesis of
uric acid, shorten and stop the acute
attack of the
gouty arthritis, prevent
gout complications that threaten life, suspend tissue and
organ damage caused by deposition of the
uric acid, thus ensure that the illness of a patient is stabilized and can not deteriorate anymore for a long time. With the
coupling medium adopted as the transdermal carrier of the
medicine, the gel is characterized in that: a dermal hydration gradient can be naturally formed in the
skin permeation course of the
coupling medium, the gradient is independent of concentration when driving
osmotic pressure difference, the gel has high deformability, can keep the components thereof unchanged after the
skin permeation course and can permeate corneum of mammals through a plurality of transformation. The gel also has high transdermal efficiency, and full dermal permeabilities are not different between species and different parts. The gel avoids the deficiencies of injections and oral liquid medicines, is safe owing to the external use, and has no
toxicity and side effects. The gel has simple components, low cost, requires no special devices and production conditions, and is available for large-scale industrialized production.