There is disclosed herein a composition for treating gastrointestinal or neurological disorders,
constipation,
functional constipation,
irritable bowel syndrome, diverticulitis, travelers
diarrhea, chronic idiopathic
nausea, IBD-associated
constipation and
diarrhea, pseudo-obstruction,
diabetic gastroparesis, cyclic
vomiting,
reflux oesophagitis,
autism enteropathy,
flatulence, halitosis,
chronic fatigue,
bloating, proctalgia fugax, Parkinsons
disease, MS, Alzheimers
Disease,
Motor Neurone Disease or
autism, the composition comprising: (i) at least two anti-clostridial agents selected from the group consisting of:
vancomycin,
vancomycin derivatives, a multi-valent
polymer of
vancomycin, aminoglycosides, nitroimidazoles, ansamysins, nifuroxazide,
colchicine,
prucalopride,
prokinetic agent and 5-
aminosalicylic acid; or (ii) at least one anti-clostridial agent selected from the above combined with an
opioid blocking agent. There is also disclosed herein a method of treating various gastrointestinal or neurological disorders,
constipation,
functional constipation,
irritable bowel syndrome, diverticulitis, travelers
diarrhea, chronic idiopathic
nausea, IBD-associated constipation and diarrhea, pseudo-obstruction,
diabetic gastroparesis, cyclic
vomiting,
reflux oesophagitis,
autism enteropathy,
flatulence, halitosis,
chronic fatigue,
bloating, proctalgia fugax, Parkinsons
disease, MS, Alzheimers
Disease,
Motor Neurone Disease or autism, the method comprising administering orally, via
enema or by
suppository: (i) a composition of the invention; (ii) at least two anti-clostridial agents selected from the group consisting of: vancomycin, vancomycin derivatives, a multi-valent
polymer of vancomycin, aminoglycosides, nitroimidazoles, ansamysins, nifuroxazide,
colchicine,
prucalopride,
prokinetic agent and 5-
aminosalicylic acid; or (iii) at least one anti-clostridial agent selected from the above and an
opioid blocking agent to a patient in need of such treatment.