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111 results about "Antipyretic" patented technology

Antipyretics are substances that reduce fever. Antipyretics cause the hypothalamus to override a prostaglandin-induced increase in temperature. The body then works to lower the temperature, which results in a reduction in fever.

Antipyretic gel

ActiveCN102319142ASignificant antipyretic (especially antipyretic in children) effectEasy to useTherapeutic coolingTherapeutic heatingEthyl hydroxybenzoateGel state
The invention discloses antipyretic gel, which comprises the following raw materials according to the following mixing relationship: 2.9 to 3.1g of carbopol, 180 to 220ml of propylene glycol, 6 to 10ml of ammonia water, 0.3 to 0.5g of ethyl p-hydroxybenzoate, 0.1 to 0.12g of menthol, 0.1 to 0.12g of borneol, 45 to 55ml of ethanol and 1000 to 1400ml of water. The raw materials are stirred and mixed into a gel state. After being adopted, the antipyretic gel has the advantages that the fever (particularly paediatric fever) curative effect is obvious, the use is simple, convenient and fast, and safety, reliability and painlessness are realized.
Owner:武汉正午阳光医药生物科技有限公司

External thermal therapy bag for treating aches and pains in human necks, shoulders, waists and legs

The invention belongs to an external thermal therapy bag made of traditional Chinese medicine for external application for treating aches and pains in human necks, shoulders, waists and legs. The conventional treatment includes medication, physical treatment, acupuncture, massage and the like. The treatment with western medicaments is usually implemented by using analgesic antipyretics which can relieve aches and pains temporarily, but are not suitable for long-term treatment. The aim of the invention is to treat aches and pains in necks, shoulders, waists and legs by combining a traditional Chinese medicinal formula and mineral elements. The 14 kinds of raw material medicaments of the external thermal therapy bag include myrrh, szechuan lovage rhizome, pepper, incised notopterygium rhizome, garden balsam stem, unprocessed radix aconite and the like; the raw material medicaments are crushed, screened and uniformly mixed with sodium chloride natural mineral element particles; and the mixed is filled into a cloth bag made of pure cotton, and cloth bag is sealed to be used as external thermal therapy bag for heating. The external thermal therapy bag has the advantages that: the clinic treatment of 208 people with cervical spondylosis show that the rate of effectiveness is 47.60 percent and that the total rate of effectiveness is up to 97.67 percent; and the aches and pains in necks, shoulders, waists and legs, which are caused by cervical spondylosis, scapulohumeral periarthritis, lumbar muscle strain, protrasion of the lumbar intervertebral disci, soft tissue injury and the like can be cured effectively.
Owner:中国人民解放军第四五一医院

Ageratum-scutellaria baicalensis antipyretic granule

The invention discloses an ageratum-scutellaria baicalensis antipyretic granule, relates to a pharmaceutical composition, and in particular relates to a pure natural botanical composition. The pure natural botanical composition is prepared from the following raw materials in parts by weight: 5-15g of ageratum, 5-15g of scutellaria, 5-15g of fructus forsythiae, 5-15g of folium isatidis, 10-20g of gypsum, 10-20g of sweet wormwood and 5-15g of radix bupleuri. Aiming at a situation that no Chinese patent medicine for treating summer-heat, dampness, cold and fever exists in the current market, the invention discloses an ageratum-scutellaria decoction for treating summer-heat, dampness, cold and fever according to many-year clinical experience, and adopts a modern pharmaceutical technology for overcoming the defects of the decoction and well achieving curative effect on treating summer-heat, dampness, cold and fever by the original prescription, and the original decoction is changed into the ageratum-scutellaria baicalensis antipyretic granule which has a good curative effect, is convenient to take and carry, has good mouthfeel and is acceptable by children.
Owner:YUNNAN UNIV OF TRADITIONAL CHINESE MEDICINE

Use of 15-methano-substituted-andrographolide derivative in preparing anti-inflammatory ntipyretic analgesic medicine

The invention discloses the application of a 15-methylene replaced andrographolide derivant as shown in general formula 1 in preparing anti-inflammatory, antipyretics and analgetics drugs, pertaining to the pharmaceutical chemistry field. Mice auricular swelling induced by dimethylbenzene, cotton ball granuloma of mice, hyperpyrexia of rats induced by yeast, mouse hot-plate test, writhing test of mice and other models are used for testifying that the 15-methylene replaced andrographolide derivant has anti-inflammatory, antipyretic and analgetic functions. Compared with andrographolide, the 15-methylene replaced andrographolide derivant has better anti-inflammatory, antipyretic and analgetic functions, and the research result of mouse acute toxicity test shows that the toxicity of the 15-methylene replaced andrographolide derivant is very slight. The 15-methylene replaced andrographolide derivant has relatively good application prospect by being applied to the development of anti-inflammatory, antipyretics and analgetics drugs.
Owner:ZHENGZHOU UNIV

Antipyretic medicine

The invention relates to an antipyretic medicine which comprises the following raw materials by weight: 30g plaster stone, 10g cortex lycii radicis, 3g indico naturalis, 15g lonicera japonica, 10g weeping forsythia, 10g radix rehmanniae, 10g chrysanthemum, 10g radix ophiopogonis, 6g radix scrophulariae and 5g mint (taking at night). A taking method of the medicine comprises the steps that the plaster stone, the cortex lycii radicis, the indico naturalis, the lonicera japonica, the weeping forsythia, the radix rehmanniae, the chrysanthemum, the radix ophiopogonis and the radix scrophulariae are mixed and put into a medicine pan; 1000g clear water is added for soaking for 30min; boiling is performed by a big fire; slow decoction is performed by a slow fire until 450g water is remained; 5g mint is added and decocted for 2min; dregs are removed; a filtrate is obtained; and a dose is taken every day after the filtrate is at a room temperature. The medicine is taken 1h after a dinner every day, and a patient can be cured after taking 2-4 doses. By clinical use demonstration, the medicine has a good effect on treating a fever and unknown heat energy; the medicine has the advantages that the medicine is high in effectiveness and low in cost, and the raw materials are easy to obtain and easy to prepare; the medicine has no toxic or side effects; and the safety of medicine use of the patient is ensured.
Owner:孙建合

Synthesis and application of ibuprofen lysine

The invention relates to synthesis and application of a medicament ibuprofen lysine. currently, the medicinal popularity of the ibuprofen lysine reaches above 95% in large cities, however, the water solubility of the ibuprofen lysine is poor, so that the preparation types and clinic application of the ibuprofen lysine are limited. The invention aims at the synthesis and application of the ibuprofen lysine, namely, preparation of high-purity compound solid bulk pharmaceutical chemical and applications of the pharmaceutical chemical as water-soluble non-steride antipyretic, analgesia and anti-inflammatory agent formulations. The synthesis method comprises the following steps: dissolving lysine in purified water so as to obtain a solution A; dissolving ibuprofen in ethanol so as to obtain a solution B; respectively adding activated carbon for decoloration and filtration, mixing, and putting the mixture in a kettle to react for 0.1-12 hours at the temperature of 0-80 DEG C; then cooling to room temperature, replenishing the ethanol, freezing and crystallizing at the temperature of minus 30 DEG C-0 DEG C; and centrifuging, washing with the ethanol, centrifugally drying, and baking, so as to obtain the white or white-like crystal ibuprofen lysine. The ibuprofen lysine has the effects that antipyretic and analgesia speed is faster than that of the ibuprofen, biological utilization degree is higher than that of the ibuprofen, toxic effect is low, and stability is good.
Owner:SHAANXI HONGFU YIYUE PHARMA

Compound antipyretic-analgesic and anti-inflammatory drug composition preparation for livestock and application thereof

ActiveCN108785681AImprove drug efficacyReduces risk of cardiovascular and gastrointestinal bleedingOrganic active ingredientsAntipyreticAnti-inflammatoryHoneysuckle
The invention discloses a compound antipyretic-analgesic and anti-inflammatory drug composition preparation for livestock and application thereof, belongs to the field of drugs for livestock, and specifically relates to a medicinal composition containing non-steroidal anti-inflammatory drugs and honeysuckle and scutellaria baicalensis extracts (honeysuckle extract chlorogenic acid and scutellariabaicalensis extract baicalin). The medicinal composition comprises the following active components in parts by mass: 1-1,000 parts of non-steroidal anti-inflammatory drugs, and 1-100 parts of honeysuckle and scutellaria baicalensis extracts. The medicinal preparation can be one or combination of injection, syrup, oral solution and other liquid preparations, common tablets, dispersible tablets, sustained release tablets, capsules, granules, powder and other solid preparations, ointments, paste, gel and other semi-solid preparations. The compound antipyretic-analgesic and anti-inflammatory drugcomposition preparation is obvious in coordination effect in animal antipyretic-analgesic and anti-inflammatory sides and can effectively reduce adverse effect of the medicine; the compound antipyretic-analgesic and anti-inflammatory drug composition preparation is obvious in treatment effect, stable in quality, high in safety, simple in preparation method, and suitable for industrial production.
Owner:四川吉星动物药业有限公司

Antipyretic and antidotal oral preparation and preparation method thereof

InactiveCN110101751AAvoid the defects of many adverse reactions such as painEasy to takeAntipyreticAnalgesicsAdditive ingredientAntibiotic Y
The invention discloses an antipyretic and antidotal oral preparation and a preparation method thereof. The antipyretic and antidotal oral preparation is prepared from, by weight, 2000-3000 parts of flos lonicerae, 2000-3000 parts of fructus forsythiae, 2000-3000 parts of spica prunellae, 1000-1500 parts of cortex moutan, 2000-3000 parts of herba taraxaci, 2000-3000 parts of gypsum, 2000-3000 parts of christina loosestrife herb and 1000-1500 parts of radix bupleuri. By using the method that distillation extraction is combined with decoction extraction, the main medicinal compositions of the medicine materials are extracted, and the corresponding oral preparation is prepared by adding corresponding ingredients according to a known oral preparation method. The defects that parenteral administration causes many adverse reactions, such as the first pass effect and pain of a patient are avoided, the oral preparation is convenient to take, no pain is caused, and the oral preparation is particularly suitable for child patients to accept. Through pharmacodynamic experiments, it is proved that the oral preparation is mainly used for viral infection, an agnogenic high fever and acute and chronic inflammation, and the oral preparation is particularly suitable for patients who are resistant or allergic to antibiotics.
Owner:西安高科陕西金方药业公司
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