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1254 results about "Radiation therapy" patented technology
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Radiation therapy or radiotherapy, often abbreviated RT, RTx, or XRT, is therapy using ionizing radiation, generally as part of cancer treatment to control or kill malignant cells and normally delivered by a linear accelerator. Radiation therapy may be curative in a number of types of cancer if they are localized to one area of the body. It may also be used as part of adjuvant therapy, to prevent tumor recurrence after surgery to remove a primary malignant tumor (for example, early stages of breast cancer). Radiation therapy is synergistic with chemotherapy, and has been used before, during, and after chemotherapy in susceptible cancers. The subspecialty of oncology concerned with radiotherapy is called radiation oncology.
Method and system for predictive physiological gating
InactiveUS6937696B1Consistent positionEasy to FeedbackSurgeryDiagnostic markersComputed tomographyEngineering
A method and system for physiological gating is disclosed. A method and system for detecting and predictably estimating regular cycles of physiological activity or movements is disclosed. Another disclosed aspect of the invention is directed to predictive actuation of gating system components. Yet another disclosed aspect of the invention is directed to physiological gating of radiation treatment based upon the phase of the physiological activity. Gating can be performed, either prospectively or retrospectively, to any type of procedure, including radiation therapy or imaging, or other types of medical devices and procedures such as PET, MRI, SPECT, and CT scans.
Owner:VARIAN MEDICAL SYSTEMS
Cone beam computed tomography with a flat panel imager
InactiveUS6842502B2Adequate visualizationReduce errorsMaterial analysis using wave/particle radiationRadiation/particle handlingX-rayAmorphous silicon
A radiation therapy system that includes a radiation source that moves about a path and directs a beam of radiation towards an object and a cone-beam computer tomography system. The cone-beam computer tomography system includes an x-ray source that emits an x-ray beam in a cone-beam form towards an object to be imaged and an amorphous silicon flat-panel imager receiving x-rays after they pass through the object, the imager providing an image of the object. A computer is connected to the radiation source and the cone beam computerized tomography system, wherein the computer receives the image of the object and based on the image sends a signal to the radiation source that controls the path of the radiation source.
Owner:WILLIAM BEAUMONT HOSPITAL
Method for preparing a radiation therapy plan
InactiveUS6560311B1Simple calculationFast executionMechanical/radiation/invasive therapiesComputer-assisted treatment prescription/deliveryDose profileIndividual dose
A method for determining a radiation treatment plan for a radiotherapy system providing multiple individual rays of intensity modulated radiation iteratively optimized the fluence of an initial set of such rays by a function that requires knowledge of only the prescribed dose and the dose resulting from the particular ray fluences. In this way, the need to store individual dose distributions of each ray are eliminated.
Owner:WISCONSIN ALUMNI RES FOUND
Cone-beam computerized tomography with a flat-panel imager
InactiveUS20030007601A1Material analysis using wave/particle radiationRadiation/particle handlingAmorphous siliconX-ray
A radiation therapy system that includes a radiation source that moves about a path and directs a beam of radiation towards an object and a cone-beam computer tomography system. The cone-beam computer tomography system includes an x-ray source that emits an x-ray beam in a cone-beam form towards an object to be imaged and an amorphous silicon flat-panel imager receiving x-rays after they pass through the object, the imager providing an image of the object. A computer is connected to the radiation source and the cone beam computerized tomography system, wherein the computer receives the image of the object and based on the image sends a signal to the radiation source that controls the path of the radiation source.
Owner:WILLIAM BEAUMONT HOSPITAL
Combined radiation therapy and imaging system and method
InactiveUS20030048868A1X-ray/infra-red processesMaterial analysis using wave/particle radiationX-rayRadiation therapy
A method of and system for locating a targeted region in a patient uses a CT imaging subsystem and a radiotherapy subsystem arranged so the targeted region can be imaged with the imaging system and treated with a beam of therapeutic X-ray radiation using a radiotherapy subsystem. The beam of therapeutic X-rays is in a plane that is substantially fixed relative to, and preferably coplanar with, a slice plane of the CT imaging subsystem so that the targeted region can be imaged during a planning phase, and imaged and exposed to the therapeutic X-rays during the treatment phase without the necessity of moving the patient.
Owner:ANLOGIC CORP (US)
System and method for imaging and treatment of tumorous tissue in breasts using computed tomography and radiotherapy
InactiveUS20060262898A1Preventing formation of vacuumInhibition formationMaterial analysis using wave/particle radiationRadiation/particle handlingMuscle tissueTumour tissue
The present invention provides a system 10 for irradiating a breast 20 of a patient 22. The system 10 comprises a gantry 12 rotatable about a horizontal axis 14 and comprising a radiation source 16 for generating a radiation beam 18 and a detector 24 spaced from the radiation source 16, and a barrier 26 disposed between the patient 22 and the gantry 12. The barrier 26 is provided with an opening 30 adapted to allow a breast 20 passing therethrough to be exposed to the radiation beam 18. In some embodiments, the barrier 26 is provided with an opening 30 adapted to allow both the breast 20 and the tissue leading from the breast to axilla and the muscle tissue of the adjacent chest wall passing therethrough to be exposed to the radiation beam 18.
Owner:VARIAN MEDICAL SYSTEMS
Methods of using and compositions comprising immunomodulatory compounds for the treatment and management of asbestos-related diseases and disorders
Methods of treating, preventing and managing an asbestos-related disease or disorder are disclosed. Specific embodiments encompass the administration of an immunomodulatory compound, or a pharmaceutically acceptable salt, solvate, hydrate, stereoisomer, clathrate, or prodrug thereof, alone or in combination with a second active agent and / or chemotherapy, surgery, or radiation therapy. Pharmaceutical compositions, single unit dosage forms, and kits suitable for use in the methods of the invention are also disclosed.
Owner:CELGENE CORP
Combination MRI and Radiotherapy Systems and Methods of Use
InactiveUS20110118588A1Magnetic measurementsDiagnostic recording/measuringRadiation therapyMagnetic field magnitude
A combination MRI and radiotherapy system comprising: a) an MRI system for imaging a patient receiving radiotherapy, comprising a magnetic field source suitable for generating a magnetic field of strength and uniformity useable for imaging, capable of being ramped up to said magnetic field in less than 10 minutes, and ramped down from said magnetic field in less than 10 minutes; b) a radiation source configured for applying radiotherapy; and c) a controller which ramps the magnetic field source down to less than 20% of said magnetic field strength when the radiation source is to be used for radiotherapy, and ramps the magnetic field source up to said magnetic field strength when the MRI system is to be used for imaging.
Owner:NAVOTEK MEDICAL
System and method for patient positioning for radiotherapy in the presence of respiratory motion
A system and method for positioning a patient for radiotherapy is provided. The method comprises: acquiring a first x-ray image sequence of a target inside the patient at a first angle; acquiring first respiratory signals of the patient while acquiring the first x-ray image sequence; acquiring a second x-ray image sequence of the target at a second angle; acquiring second respiratory signals of the patient while acquiring the second x-ray image sequence; synchronizing the first and second x-ray image sequences with the first and second respiratory signals to form synchronized first and second x-ray image sequences; identifying the target in the synchronized first and second x-ray image sequences; and determining three-dimensional (3D) positions of the target through time in the synchronized first and second x-ray image sequences.
Owner:SIEMENS MEDICAL SOLUTIONS USA INC
Radiation therapy method with target detection
InactiveUS20060182326A1Character and pattern recognitionRadiation beam directing meansRadiation therapyThree dimensional planning
A method for delivering radiation therapy to a patient using a three-dimensional planning image for radiation therapy of the patient wherein the planning image includes a radiation therapy target. The method includes the steps of: determining desired image capture conditions for the capture of at least one two-dimensional radiographic image of the radiation therapy target using the three-dimensional planning image; detecting a position of the radiation therapy target in the at least one captured two-dimensional radiographic image; and determining a delivery of the radiation therapy in response to the radiation therapy target's detected position in the at least one captured two-dimensional radiographic image.
Owner:CARESTREAM HEALTH INC
Dynamic radiation therapy simulation system
InactiveUS7349522B2Accurate treatment of tumorAccurate imagingMaterial analysis using wave/particle radiationRadiation/particle handlingFluoroscopic imageComputerized system
A system for dynamic treatment simulation for radiotherapy. Software is implemented on a computer system to perform dynamic simulation by displaying every segment of dynamic treatment beams on top of real-time fluoroscopic image sequences. Automated distortion correction of the fluoroscopic image due to the image intensifier is performed in real-time. A respiration phase indicator measures changes in circumference of the patient's chest through the movement of a radio-opaque marker that appears directly in the fluoroscopic images of the patient.
Owner:THE BOARD OF TRUSTEES OF THE UNIV OF ARKANSAS
Membrane-permeant peptide complexes for medical imaging, diagnostics, and pharmaceutical therapy
Methods and compositions for medical imaging, evaluating intracellular processes and components, radiotherapy of intracellular targets, and drug delivery by the use of novel cell membrane-permeant peptide conjugate coordination and covalent complexes having target cell specificity are provided. Kits for conjugating radionuclides and other metals to peptide coordination complexes are also provided.
Owner:WASHINGTON UNIV IN SAINT LOUIS
Method using 3-(4-amino-1-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione for treatment of certain leukemias
InactiveUS20060030594A1Prevent proliferationBiocidePeptide/protein ingredientsCompound (substance)Radiation therapy
Methods of treating, preventing or managing leukemias are disclosed. The methods encompass the administration of an immunomodulatory compound of the invention known as Revlimid® or lenalidomide. The invention further relates to methods of treatment using this compound with chemotherapy, radiation therapy, hormonal therapy, biological therapy or immunotherapy. Pharmaceutical compositions and single unit dosage forms suitable for use in the methods of the invention are also disclosed.
Owner:CELGENE CORP
Method and apparatus for shielding a linear accelerator and a magnetic resonance imaging device from each other
InactiveUS20110012593A1Improve permeabilityReduce flux densityDiagnostic recording/measuringSensorsSplit magnetResonance
A radiation therapy system comprises a magnetic resonance imaging (MRI) system combined with an irradiation system, which can include one or more linear accelerators (linacs) that can emit respective radiation beams suitable for radiation therapy. The MRI system includes a split magnet system, comprising first and second main magnets separated by gap. A gantry is positioned in the gap between the main MRI magnets and supports the linac(s) of the irradiation system. The gantry is rotatable independently of the MRI system and can angularly reposition the linac(s). Shielding can also be provided in the form of magnetic and / or RF shielding. Magnetic shielding can be provided for shielding the linac(s) from the magnetic field generated by the MRI magnets. RF shielding can be provided for shielding the MRI system from RF radiation from the linac.
Owner:VIEWRAY TECH
High energy polyenergetic ion selection systems, ion beam therapy systems, and ion beam treatment centers
InactiveUS20060145088A1High energySuitable as therapeuticThermometer detailsBeam/ray focussing/reflecting arrangementsHigh energyIon beam
Devices and methods are provided for generating laser-accelerated high energy polyenergetic positive ion beams that are spatially separated and modulated based on energy level. The spatially separated and modulated high energy polyenergetic positive ion beams are used for radiation therapy. In addition, methods are provided for treating patients in radiation treatment centers using therapeutically suitable high energy polyenergetic positive ion beams that are provided by spatially separating and modulating positive ion beams. The production of radioisotopes using spatially separated and modulated laser-accelerated high energy polyenergetic positive ion beams is also provided.
Owner:INST FOR CANCER RES
Method and system for predictive physiological gating
InactiveUS20050201510A1Consistent positionEasy to FeedbackSurgeryDiagnostic markersRetrospective gatingComputed tomography
A method and system for physiological gating is disclosed. A method and system for detecting and predictably estimating regular cycles of physiological activity or movements is disclosed. Another disclosed aspect of the invention is directed to predictive actuation of gating system components. Yet another disclosed aspect of the invention is directed to physiological gating of radiation treatment based upon the phase of the physiological activity. Gating can be performed, either prospectively or retrospectively, to any type of procedure, including radiation therapy or imaging, or other types of medical devices and procedures such as PET, MRI, SPECT, and CT scans.
Owner:VARIAN MEDICAL SYSTEMS
Ion radiation therapy system with variable beam resolution
ActiveUS20090189095A1Accurate depictionSmall featureElectrode and associated part arrangementsMachines/enginesLight beamTrade offs
Owner:WISCONSIN ALUMNI RES FOUND
Charged particle cancer therapy and patient breath monitoring method and apparatus
The invention comprises a patient respiration monitoring and / or control method and apparatus used in conjunction with multi-axis charged particle or proton beam radiation therapy of cancerous tumors. The respiration monitoring system uses thermal and / or force sensors to determine where a patient is in a respiration cycle in combination with a feedback signal control delivered to the patient to inform the patient when breath control is required. The resulting breath control is timed with charged particle delivery to the tumor to enhance accuracy, precision, and / or efficiency of tumor treatment.
Owner:BALAKIN ANDREY VLADIMIROVICH +1
Combined radiation therapy and magnetic resonance unit
ActiveUS20080208036A1Avoid huge expensesHigh quality imagingMagnetic measurementsDiagnostic recording/measuringResonanceRadiation therapy
The invention relates to a combined radiation therapy and magnetic resonance unit. For this purpose, in accordance with the invention a combined radiation therapy and magnetic resonance unit is provided comprising a magnetic resonance diagnosis part with an interior, which is limited in radial direction by a main magnet, and a radiation therapy part for the irradiation of an irradiation area within the interior, wherein at least parts of the radiation therapy part, which comprise a beam deflection arrangement, are arranged within the interior.
Owner:SIEMENS HEALTHCARE GMBH
Pro-neurogenic compounds
This technology relates generally to compounds and methods for stimulating neurogenesis (e.g., post-natal neurogenesis, including post-natal hippocampal and hypothalamic neurogenesis) and / or protecting neuronal cell from cell death. Various compounds are disclosed herein. In vivo activity tests suggest that these compounds may have therapeutic benefits in neuropsychiatric and / or neurodegenerative diseases such as schizophrenia, major depression, bipolar disorder, normal aging, epilepsy, traumatic brain injury, post-traumatic stress disorder, Parkinson's disease, Alzheimer's disease, Down syndrome, spinocerebellar ataxia, amyotrophic lateral sclerosis, Huntington's disease, stroke, radiation therapy, chronic stress, abuse of a neuro-active drug, retinal degeneration, spinal cord injury, peripheral nerve injury, physiological weight loss associated with various conditions, as well as cognitive decline associated with normal aging, chemotherapy, and the like.
Owner:BOARD OF RGT THE UNIV OF TEXAS SYST
Histone deacetylase inhibitors and methods of use thereof
The invention provides novel classes of HDAC inhibitors. Methods of sensitizing a cancer cell to the cytotoxic effects of radiotherapy are also provided as well as methods for treating cancer and methods for treating neurological diseases. Additionally, the invention further provides pharmaceutical compositions comprising an HDAC inhibitor of the invention, and kits comprising a container containing an HDAC inhibitor of the invention.
Owner:GEORGETOWN UNIV
Patient positioning device
ActiveUS7741623B2Assure freedomKeep postureRadioactive sourcesChemical conversion by chemical reactionCouplingComputer module
Owner:VARIAN MEDICAL SYST PARTICLE THERAPY GMBH & CO KG
Charged particle cancer therapy imaging method and apparatus
ActiveUS20110147608A1Stability-of-path spectrometersMaterial analysis by optical meansBeam energyBeam trajectory
The invention relates to a method and apparatus for treatment of a solid tumor. More particularly, the invention comprises a multi-axis and / or multi-field charged particle cancer therapy system. In one embodiment, the tumor is imaged from multiple directions in phase with patient respiration. The two-dimensional images are combined to produce a three-dimensional picture of the tumor relative to patient features. The resulting three-dimensional image is used in generation of a radiation treatment plan and subsequent radiation therapy with the radiation beam in terms of control of two-dimensional beam trajectory, delivered beam energy, delivered beam intensity, and / or beam velocity each as a function of patient vertical translation position, patient rotation position, and / or patient respiration.
Owner:BALAKIN ANDREY VLADIMIROVICH +1
Systems and methods for treating a patient using radiation therapy
Apparatus and methods for treating a patient using radiation therapy. In one embodiment, an apparatus comprises a tube configured to receive a radiation source and an expandable member. The tube has a first end configured to be inserted into a patient and a second end that is generally configured to remain external to the patient. The expandable member is at the first end of the tube, and it is configured to contain the radiation source. The expandable member can comprise a balloon, flexible bladder, mechanical linkage (e.g., a cage), a mesh, or other suitable expandable systems. The apparatus further includes a marker associated with the expandable member such that the marker moves with the expandable member.
Owner:VARIAN MEDICAL SYSTEMS
Method of modulating laser-accelerated protons for radiation therapy
InactiveUS7268358B2Minimize radiationMaximize radiationStability-of-path spectrometersElectrode and associated part arrangementsNuclear medicineRadiation therapy
Owner:INST FOR CANCER RES
Radiation therapy method with target detection
InactiveUS7453983B2Character and pattern recognitionRadiation beam directing meansRadiation therapyThree dimensional planning
A method for delivering radiation therapy to a patient using a three-dimensional planning image for radiation therapy of the patient wherein the planning image includes a radiation therapy target. The method includes the steps of: determining desired image capture conditions for the capture of at least one two-dimensional radiographic image of the radiation therapy target using the three-dimensional planning image; detecting a position of the radiation therapy target in the at least one captured two-dimensional radiographic image; and determining a delivery of the radiation therapy in response to the radiation therapy target's detected position in the at least one captured two-dimensional radiographic image.
Owner:CARESTREAM HEALTH INC
Integrated external beam radiotherapy and MRI system
ActiveUS20090149735A1Reduce RF NoiseEasy to operateDiagnostic recording/measuringSensorsMri imageIrradiation
A radiation therapy system comprises a radiation source generating a beam of radiation and a magnetic resonance imaging apparatus. An interface acts between the radiation source and the MRI apparatus that permits irradiation to be performed simultaneously with imaging. The MRI apparatus and radiation source are coupled such that the system can be used in a rotation mode whereby the radiation source can irradiate a subject from basically any angle without reducing MRI image quality.
Owner:ALBERTA HEALTH SERVICES
Method of modulating laser-accelerated protons for radiation therapy
InactiveUS20070034812A1Maximize polyenergetic proton radiationMinimize radiationMaterial analysis using wave/particle radiationRadiation/particle handlingRadiation therapyProton radiation
Owner:INST FOR CANCER RES
Method for reconstruction of limited data images using fusion-aligned reprojection and normal-error-aligned reprojection
InactiveUS6915005B1Reduce artifactsEnhance the imageReconstruction from projectionCharacter and pattern recognitionComplete dataRadiation therapy
The present invention provides methods of using current but incomplete data to prepare an approximated complete image of a patient potentially undergoing radiation therapy. A complete image of the patient is fused or aligned with a limited patient image using image registration techniques. The aligned image is converted to sinogram data. This sinogram data is compared to sinogram data corresponding to the limited patient image to determine what data exists beyond the scope of the limited sinogram. Any additional data is added to the limited data sinogram to obtain a complete sinogram. This complete sinogram is then reconstructed into an image that approximates the complete image that would have been taken at the time the limited image was obtained.
Owner:TOMOTHERAPY INC
Computer assisted radiotherapy dosimeter system and a method therefor
InactiveUS6650930B2Precise positioningEasy to recordSurgeryRadiation diagnosticsDosimetry radiationDosimeter
In order to facilitate the display and evaluation of data acquired while irradiating a body, e.g. a patient undergoing radiation therapy, a dosimetry system has a plurality of sensors for disposition on, in or near the body to be irradiated and connected to a sensor reading instrument which is interfaced with a display system, for example a personal computer, which is arranged to display, in use, one or more representations, for example drawings or photographs, of the body to be irradiated, along with the positions and the dose data for those specific locations where the dosimeter sensors were placed.
Owner:BEST THERATRONICS +1
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