189 results about "Hypothalamus" patented technology

The present invention concerns the use of an agonist of an hypothalamic hormone for the preparation of a pharmaceutical agent to support the luteal phase during infertility treatment of female mammals and more specifically of woman. According to this invention, the pharmaceutical agent is suitable to be used for supporting the luteal phase after a spontaneous ovulation or after stimulation of follicular growth, trigger of final follicular maturation and ovulation with one or several additional agents.

Methods of reducing food intake and glucose production in a mammal, or restoring hepatic autoregulation are provided. The methods involve increasing long-chain fatty acyl-Co-A (LC-CoA) levels in the hypothalamus, or stimulating efferent fibers in the hepatic branch of the vagus nerve. Also provided are methods of increasing food intake and glucose production in a mammal. The methods involve decreasing long-chain fatty acyl-Co-A (LC-CoA) levels in the hypothalamus of the mammal.

The invention relates to a method of altering hypothalamic function in an individual. The method comprises nasally administering a human semiochemical, e.g. an Estrene steroid, or a pharmaceutical composition containing an Estrene steroid, such that the ligand semiochemical binds to a specific neuroepithelial receptor. The steroid is preferably administered in the form of a pharmaceutical composition containing one or more pharmaceutically acceptable carriers. Other embodiments of the invention include pharmaceutical compositions containing the steroids.

The invention provides a voice separating method based on an auditory center system under the multi-sound-source environment, and relates to the field of digital signal processing. The voice separating method solves the boundedness that most voice recognition methods can only be used under the low-noise and single-sound-source environment. To carry out the voice recognition under the multi-sound-source noisy environment, voice separation needs to be achieved firstly. According to the voice separating method based on the auditory center system, the multi-spectra analysis is carried out on voice signals through a peripheral hearing model, a coinciding nerve cell comprises a general cynapse model and a general cell model to integrate the information of an ITD and the information of an ILD, the voice separation is achieved in a hypothalamus cell model, and the experiment shows that the method has good robustness.

Normal and abnormal diurnal cortisol secretion patterns are identified from human saliva samples by an in vitro method. First and second saliva samples are taken from one human individual at first and second predetermined times during the same day. A first cortisol concentration is determined in the first saliva sample, and a second cortisol concentration is determined in the second saliva sample. An abnormal secretion pattern is then compared to a normal secretion pattern with the help of a fuzzy logic algorithm. A function of the hypothalamic-pituitary-adrenal (HPA) axis is then determined for the human individual. Optionally, a testosterone level is determined from one of the samples and is used in combination with the cortisol concentrations to provide a redefined determination.

The present invention discloses a pharmaceutical preparation of Chinese herbal medicines which consists of Chinese herbal medicines for tonifying kidney and antiasthma, wherein the Chinese herbal medicines are Perilla Frutescens, Prunus Armeniaca, Glycyrrhiza Uralensis, Scutellaria Baicalensis, Coptis Chinesis, Tusilago Farfara, Stemona Sessilifolia, Fritllaria Cirrhosa, Pheretima Aspergillum, Psoralea Corylifolia, Codonopsis Pilosula, Hordeum Vulgara, Massa Fermentata Medicalis, Schisandra Chinensis, Gypsum. The preparation has been used in China for 20 years, and in Israel for more than 5 years. It has been used to treat thousands of patients suffering from asthma with an effective rate of 93%. The present preparation can relieve cough, expel phlegm, resist airway allergic inflammation reaction, improve pulmonary function, partial pressure of the oxygen in blood and increase CD2, CD4, CD4 / CD8, reduce IgE in blood, and increase CAMP, reduce CGMP, stabilize mast cells, inhibit the release of histamine, which makes it capable of stopping the attack of asthma. As shown with an electron microscope, the preparation protects lung cells, increases lung cells of type 2, and recovers the lung's capacity. It can be applied to the hormone dependent patients for decreasing and ceasing the administration of hormone by adjusting hypothalamic-pituitary-adrenal axis. To further demonstrate the therapeutic effect, a clinical trial carried in the Tel-Hashomer Hospital of Israel proved the preparation can improve asthma significantly.

The present invention provides a method of promoting weight loss, or treating or preventing a body disorder related to excess weight, in a subject. The method comprises administering to the subject an effective amount of a creatine uptake inhibitor. Administration of the creatine uptake inhibitor is intracranial or directed to the hypothalamus. The invention further provides a method of screening for a novel compound that inhibits creatine uptake in the hypothalamus.