43 results about "Normal aging" patented technology

This technology relates generally to compounds and methods for stimulating neurogenesis (e.g., post-natal neurogenesis, including post-natal hippocampal and hypothalamic neurogenesis) and/or protecting neuronal cell from cell death. Various compounds are disclosed herein. In vivo activity tests suggest that these compounds may have therapeutic benefits in neuropsychiatric and/or neurodegenerative diseases such as schizophrenia, major depression, bipolar disorder, normal aging, epilepsy, traumatic brain injury, post-traumatic stress disorder, Parkinson's disease, Alzheimer's disease, Down syndrome, spinocerebellar ataxia, amyotrophic lateral sclerosis, Huntington's disease, stroke, radiation therapy, chronic stress, abuse of a neuro-active drug, retinal degeneration, spinal cord injury, peripheral nerve injury, physiological weight loss associated with various conditions, as well as cognitive decline associated with normal aging, chemotherapy, and the like.

The present invention relates to the enhancement of cognition in an individual by delivery of a histone acetylation regulator, such as a histone deacetylase inhibitor. The individual may have normal or poor memory, and the poor memory may be the result of a pathogenic condition or a non-pathogenic condition, such as with normal aging-related impairment. In a specific embodiment, enhancement of cognition occurs in an individual having a mental retardation syndrome.

This technology relates generally to compounds and methods for stimulating neurogenesis (e.g., post-natal neurogenesis, including post-natal hippocampal and hypothalamic neurogenesis) and/or protecting neuronal cell from cell death. Various compounds are disclosed herein. In vivo activity tests suggest that these compounds may have therapeutic benefits in neuropsychiatric and/or neurodegenerative diseases such as schizophrenia, major depression, bipolar disorder, normal aging, epilepsy, traumatic brain injury, post-traumatic stress disorder, Parkinson's disease, Alzheimer's disease, Down syndrome, spinocerebellar ataxia, amyotrophic lateral sclerosis, Huntington's disease, stroke, radiation therapy, chronic stress, abuse of a neuro-active drug, retinal degeneration, spinal cord injury, peripheral nerve injury, physiological weight loss associated with various conditions, as well as cognitive decline associated with normal aging, chemotherapy, and the like.

The invention provides a method for predicting life of transformer insulation and a management system thereof. The technical proposal of the method comprises the steps as follows: firstly essential data is input; subsequently, transformer winding hot-spot temperature theta i, the total working-hour number of each hot-spot temperature tau i, each temperature relative heat aging rate Vhi, main transformer insulation each temperature relative life loss Li and insulation accumulation relative life loss Lh are calculated step by step; then the design life Lo of a transformer under a normal aging state is confirmed; transformer insulation remaining aging life Hrl is calculated; and finally, a recommended maintenance treatment measure is obtained. A product provided by the invention is the life management system consisting of a calculation/application server and software, a database server, an external system interface, a transformer primary side current and environment temperature measuring instrument, a web page server and a client browser. The invention has the advantage of being capable of predicting the remaining life of the transformer insulation quantificationally during a using stage.

The present invention provides methods for improving cognitive function, improving mood, and decreasing aggression in a normal adult subject, and in a subject having symptoms characteristic of a neurological disorder, by administration of a nutriceutical formulation of the invention to the subject. The invention additionally features methods of treating neurological disorders, depression, and aggression using nutriceutical formulations. Nutriceutical compositions and formulations for use in the methods of the invention, and kits containing nutriceutical compositions and formulations, are also provided.

The invention discloses a heat treatment technique for improving the aging post plasticity of cold forming Beta titanium alloy. The technique comprises the following steps of: carrying out short time aging at the normal aging temperature to Beta titanium alloy treated by solid solution and cold deformation, then properly improving the aging temperature for holding temperature for short time so as to eliminate deforming defects of dislocation remained by cold deformation and the like by a high-temperature restoring mechanical part, thus leading the plasticity of materials to be restored under the premise of guaranteeing the strength of alloy and shortening the aging time. The technique has simple operation and easy implementation and is suitable for batch processing in the industrial production process.

The invention provides a power transformer time-varying outage risk assessment method considering weather factors. The method comprises the following steps: S1, establishing a comprehensive meteorological risk index system influencing the operation state of the power transformer; S2, according to the aging failure probability and accidental failure probability of the power transformer, obtaining the comprehensive time-varying operation failure probability of the power transformer; S3,using synthetic meteorological risk index to modify the synthetic time-varying operation failure probability ofthe power transformer, and obtaining the time-varying outage risk assessment model of the power transformer considering weather factors. According to the power transformer time-varying outage risk assessment method of the present invention, the meteorological factors which have great influence on the stable operation of transformer are quantified, and the fault outage model of transformer considering normal aging and accidental fault is optimized by using the synthesized meteorological risk index, and the time-varying outage risk model considering weather factors is obtained to make the riskassessment of transformer more accurate.

A method to increase both the libido and sexual responsiveness in a mammalian female. The method comprises the steps of administering a compound having a combination of DHEA, Yohimbe and L-arginine to that female. When a woman's decreased or absent libido, currently referred to in the medical literature as hypoactive sexual desire, is believed in the gynecologic/urologic communities to be caused by a decreased "testosterone effect', such treatment may be beneficial. This decreased "testosterone effect' can be due to normal aging, contraceptive medications, anti-depressant medication, a lowered cholesterol diet or a decreased percentage of body fat as a result of a rigorous exercise regime. This present invention defines those three above-stated specific nutritional supplements with specific physiological effects well documented in the peer reviewed medical literature. This combination of nutritional supplements increases the testosterone effect in both the brain as well as in the clitoral tissues, to improve a woman's libido, without prescription testosterone preparations, or the uncertainties of non-medically proven herbal remedies.

The invention relates to a device for processing the neighbor discovery (ND) item of a router, which comprises a microcode transmission module, a transmission table management module and an ND protocol module, wherein the microcode transmission module is used for counting the used times of the ND item when transmitting a message through the neighbor discovery item; the transmission table management module is used for providing the count number of the ND item for the ND protocol module; the ND protocol module is used for reading and accumulating the count number of the ND item of each line card through the transmission table management module when the ND item is just changed into a stale state, and reading and accumulating the count number of the ND item of each line card again after the ND item is kept in the stale state for a specific time, wherein the accumulated results of the ND item read in two times are compared, and the ND item is aged and deleted if the accumulated results of the ND item read in two times are the same. Moreover, the invention further provides a method for processing the ND item of a router. Through the technical scheme of the invention, the normal aging for the ND item is ensured, and packet loss is avoided.

The invention discloses an LED aging device, and the device comprises a support. The support is provided with a multilayer installation frame, and the installation frame is provided with lamp holders which are arranged in rows. The lamp holders are connected with a testing power supply, and the support is provided with an air supply port and an air outlet. The air supply port and the air outlet are respectively disposed at two ends of the support. The air supply port is connected with a centrifugal fan through an air pipe. The air supply port and the air outlet are respectively disposed at two ends of the support, thereby enabling the air in the device to be able to circulate quickly, thereby enabling heat generated in the aging process of a large number of LED lamps to be dissipated quickly, enabling the air temperature of the interior of the device to remain normal, and guaranteeing the normal aging of the lamps.

The present invention relates to compounds of general formula I wherein R¹, R², R³ and R⁴ are as defined herein which maybe used for the treatment of schizophrenia, obsessive-compulsive

personality disorder, major depression, bipolar disorders, anxiety disorders, normal aging, epilepsy, retinal degeneration, traumatic brain injury, spinal cord injury, post-traumatic stress disorder, panic disorder, Parkinson's disease, dementia, Alzheimer's disease, cognitive impairment, chemotherapy-induced cognitive dysfunction (“chemobrain”), Down syndrome, autism spectrum disorders, hearing loss, tinnitus, spinocerebellar ataxia, amyotrophic lateral sclerosis, multiple sclerosis, Huntington's disease, stroke, and disturbances due to radiation therapy, chronic stress, optic neuropathy or macular degeneration, or abuse of neuro-active drugs, selected from alcohol, opiates, methamphetamine, phencyclidine and cocaine.

The invention discloses a hydrogen atom frequency standard ionization bubble aging method. The problems that in the prior art, ionization bubbles take a long time to reach the normal aging brightnessis poor in batch consistency and uncontrollable in product development cycle are solved. The method comprises the following steps that an HF solution with the concentration being 25%-50% is injected into ionization bubbles, and ionization bubbles are placed in a water tank for 30 minutes to 1 hour; the HF solution in the ionization bubbles is washed with pure water; and the ionization bubbles is injected with absolute ethyl alcohol, and an operator waits for evaporation of the absolute ethyl alcohol. Through the hydrogen atom frequency standard ionization bubble aging method, the time requiredfor the ionization bubble to reach a normal working state can be effectively shortened and is shortened to less than two days from longer than a week, the batch aging success rate reaches 100%, raw materials are saved, the cost is reduced, the product quality and labor productivity are improved, and guarantee is provided for control over the hydrogen atom frequency standard development cycle.

The invention belongs to the field of coating and particularly relates to a high light-retaining and color-retaining acrylic acid modified polyurethane finishing coat and a preparation method thereof.The finishing coat contains a component A and a component B in a weight ratio of 100 to (20-30), wherein the component A contains the following raw materials in parts by weight: 40-50 parts of an acrylate emulsion, 50-60 parts of a polyurethane emulsion, 3-6 parts of an enhancer, 10-15 parts of pigments and fillers, 1-3 parts of a dispersing agent, 0.5-1 part of a defoaming agent, 0-5 parts of other aids and the balance of deionized water; and the component B is a water-based curing agent. The adopted enhancer contains a benzophenone structure with an excellent light stabilization effect andis cable of strongly absorbing ultraviolet light, so that the damage caused by the ultraviolet light to the finishing coat is avoided; and meanwhile, the enhancer has no possibility of being decomposed and decolorized, further contains an N-cyclohexyl p-methoxyaniline structure and has good ozone aging performance, radiation aging resistance and normal aging resistance, and the structure is not decolorized after being placed in air and sunlight for a long time, so that the finishing coat with high light-retaining and color-retaining properties is obtained.