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551 results about "Energy metabolism" patented technology

Energy metabolism is generally defined as the entirety of an organism's chemical processes. These chemical processes typically take the form of complex metabolic pathways within the cell, generally categorized as being either catabolic or anabolic.

Method for establishing obese rat animal model based on CRISPR (clustered regularly interspaced short palindromic repeat) gene knockout technology

InactiveCN103614415AImprove the level ofDeepen understanding of gene regulationVector-based foreign material introductionAnimal husbandryDiseaseLepr gene
The invention provides a method for establishing an obese rat animal model based on a CRISPR (clustered regularly interspaced short palindromic repeat) gene knockout technology. The method comprises the following steps: (1) establishing an Lep / Lepr gene knockout rat model; (2) carrying out the authentication and related analysis on the obese rat animal model; (3) evaluating the energy metabolism and the body fat rate of the obese rat animal model. According to the method, a CRISPR / Cas system is used for respectively or simultaneously knocking out Lep and LepR genes so as to obtain the rat model modified by a corresponding target gene, so that the understanding of gene regulation in the obesity morbidity process can be deepened, and the high-level animal model can be provided for the translational medicine and the new medicine research and development.
Owner:SUZHOU TONGSHAN BIO TECH

Methods for enhancing energy metabolism

The invention provides methods for one or more of enhancing energy metabolism, promoting healthy energy metabolism, maintaining healthy energy metabolism, preventing conditions that result in a decline or deficiency in energy metabolism, treating conditions that result in a decline or deficiency in energy metabolism, and preventing the accumulation of excess body fat in animals without reducing energy intake by the animals. The methods comprise administering isoflavones to the animals, preferably in amounts of from about 0.001 to about 10 g / kg / day.
Owner:SOC DES PROD NESTLE SA

Novel inhibitors of glutaminyl cyclase

The present invention relates to novel inhibitors of glutaminyl cyclase and combinations thereof for the treatment of neuronal disorders, especially Alzheimer's disease, Down Syndrome, Parkinson disease, Chorea Huntington, pathogenic psychotic conditions, schizophrenia, impaired food intake, sleep-wakefulness, impaired homeostatic regulation of energy metabolism, impaired autonomic function, impaired hormonal balance, impaired regulation, body fluids, hypertension, fever, sleep dysregulation, anorexia, anxiety related disorders including depression, seizures including epilepsy, drug withdrawal and alcoholism, neurodegenerative disorders including cognitive dysfunction and dementia.
Owner:VIVORYON THERAPEUTICS NV

System for recognizing human gait, real-time monitoring energy consumption thereof and instructing exercise training thereof

The invention relates to a system for recognizing human gait, real-time monitoring energy consumption thereof and guiding exercise training thereof, comprising a functional innersole, a data storage display system and a health auxiliary guidance system. The system is characterized in that the functional innersole comprises an amorphous wire pressure sensor measuring human pressure and a data acquisition processing system which are embedded; the data storage display system sets system initial parameters and individual parameters through the input of keys and sends the parameters to the data acquisition processing system in the functional innersole through a wireless communication module; the data of the data acquisition processing system are wirelessly sent to the data storage display system, and a display interface on the data storage display system displays the information such as gait, step number, step frequency, energy consumption, time for exercise, and the like; and the data stored in the data storage display system are uploaded to a personal computer, and energy metabolism analysis for an exerciser is carried out and training guidance and training reference are provided under the help of the health auxiliary guidance system in the personal computer. The invention has low energy consumption, high sensitivity, quick response time, high anti-interference ability and low cost.
Owner:北京国浩微磁电子智能传感器技术研究所

Cryopreservation media and molecules

The cryopreservation media utilizes naturally occurring endogenous molecules and their chemical derivatives which act as osmotically active cryopreservative agents as well as molecules which insert into and protect specific regions of cellular membranes, lead to membrane repair, maintain normal cellular levels of energy metabolites, and act as antioxidants. Cryoperserved cells can be returned to a pre- cryopreservation state without damaging the cells resulting in a very high survival rate.
Owner:PETTEGREW JAY W +3

Perfect compound feed with low nitrogen and phosphorus emissions for feeding culter alburnus and preparation method of perfect compound

The invention discloses a perfect compound feed with low nitrogen and phosphorus emissions for feeding culter alburnus and a preparation method of the perfect compound feed. The perfect compound feed comprises the following raw materials: fish meal, puffed bean pulp, puffed beans, shrimp shell meal, DDGS, vegetable cake, cottonseed meal, wheat, monocalcium phosphate, multi-vitamin premix, polymineral premix, fish oil, lard oil, vegetable oil, compound amino acid, granulesten, glycine betaine, choline chloride, phytase, purple perilla and the like. The prepared perfect compound feed has the characteristics that the protein utilization efficiency is high; the decomposition of protein into amino acid for energy metabolism is alleviated by amino acid balance; the energy utilization of lipid is improved by adjusting lipid metabolism and hepatoprotective effect; the utilization rate of phosphorus in the feed is high; phytate phosphorus is degraded by mainly selecting special phytase and is changed into effective phosphorus for use; the properties of the feed are ensured by a production process of puffing and pelletizing at high temperature and spraying at low temperature; the feed is reasonable in formula; the processing process of the feed is scientific; the nitrogen and phosphorus emissions are reduced; the requirements on healthful aquaculture of the culter alburnus can be met.
Owner:JIANGXI AGRICULTURAL UNIVERSITY

Treatment of pets with sirtuin activators

InactiveUS20160000737A1Regulating energy metabolismReduce weightBiocideLiquid surface applicatorsMetaboliteReady to use
The present invention provides for systems, compositions, methods and kits for regulating energy metabolism in pets. The systems, compositions, and kits can comprise, and methods can make use of, pet foods, pet treats, pet supplements, and pet drinks. In one aspect, the invention provides for pet food, treat, supplement, and drink compositions that comprise a combination of (a) leucine, and (b) a sirtuin activator, or any precursors or metabolites of (a) or (b). These combinations may be effective for reducing weight or adipose volume in the pet. In another aspect, the invention provides for methods of regulating energy metabolism by the administration of one or more compositions comprising leucine, a leucine metabolite, and / or a sirtuin activator. The invention also provides for kits comprising compositions of leucine, a leucine metabolite, and / or a sirtuin activator packaged in an oral dose form with usage instructions.
Owner:NUSIRT SCI

Aryl - Hydroxyethylamino - Pyrimidines and Triazines as Modulators of Fatty Acid amide Hydrolase

Certain aryl-hydroxyethylamino-pyrimidine and triazine compounds are described, which are useful as FAAH inhibitors. Such compounds may be used in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by fatty acid amide hydrolase (FAAH) activity, such as anxiety, pain, inflammation, sleep disorders, eating disorders, energy metabolism disorders, and movement disorders (e.g., multiple sclerosis). Methods of synthesizing such compounds are also disclosed.
Owner:JANSSEN PHARMA NV

Non-invasive blood sugar measuring method and fingertip measuring probe

The present invention discloses a non-invasive blood glucose measurement method, applied to noninvasive blood glucose measuring instruments including measuring hosts and fingertip measuring probes, comprising pre-storing a random forest algorithm and a neural network prediction algorithm in the measuring host; measuring energy metabolism parameters of a fingertip of an individual to be measured and transmitting the parameters to the measuring host by the fingertip measuring probe; calling the random forest algorithm to predict the blood glucose type of the energy metabolism parameters of the fingertip of the individual to be measured and calling the corresponding neural network prediction algorithm to calculate the blood glucose value of the fingertip of the individual to be measured by the measuring host. The present invention also provides a fingertip-measuring probe. The non-invasive blood glucose measurement method disclosed in the present invention can be applied to non-invasive measurement of blood glucose, parameters related to energy metabolism of human body, healthy parameters of angiocarpy, etc.
Owner:GUILIN MEDICINE ELECTRONICS TECH CO LTD +1

Production method of bacillus amyloliquefaciens antimicrobial lipopeptide and application thereof in prawn feed

InactiveCN103478509AAntibacterial Broad Spectrum High EfficiencySolve bottlenecksAnimal feeding stuffAccessory food factorsBiotechnologyFeed additive
The invention relates to a production method of bacillus amyloliquefaciens antimicrobial lipopeptide and application thereof in prawn feeds and belongs to the technical fields of aquiculture and biology in the field of agriculture. The production method comprises the following steps that bacillus amyloliquefaciens fmb-50 with the collection number of CGMCC No.6249 is used as a strain and is sequentially subjected to seed culture, amplification culture and fermentation production to obtain fermentation liquor; the thalli of the fermentation liquor are removed through microfiltration or membrane filtration and nanofiltration; corn starch or porous starch is added for absorption and spray drying is carried out, thus obtaining an antibacterial substance feed additive with the antibacterial valence of 40000-50000 IU/g or 250000 IU/g. The antibacterial substance which is produced from the bacillus amyloliquefaciens fmb-50 through fermentation can be industrially produced in a large scale; the production period is short and production cost is greatly reduced; when used in the prawn feeds, the antibacterial substance can reduce the mortality rate, improve the utilization ratio of the prawn feeds, promote the nonspecific immunoreaction of prawns and enhance the energy metabolism level.
Owner:NANJING AGRICULTURAL UNIVERSITY +2

Medicine for treating male oligozoospermia and improving semen quality and preparation method of medicine

The invention relates to a medicine for treating male oligozoospermia and improving semen quality. Various natural edible plant medicines such as Rhizoma Polygonati, Fructus Lycii, Cordyceps militaris (L.) Link., Fructus Rubi, Fructus Mori, Fructus Hippophae, Semen Coicis, Radix Ginseng, and Concha Ostreae (calcined) serve as raw materials, are combined suitably, and jointly have effects of invigorating the spleen and replenishing Qi, and nourishing the kidney and replenishing essence, Lepidium Meyenii contains macaenes and macamides which are used as active substances has effects of promoting sexual function, increasing the number of sperms and improving activity of the sperms, selenium yeast, aminoacid, L-carnitine tartrate, calcium carbonate and fructose can strengthen and protect energy metabolism of the sperms, taurine and vitamin effectively remove reactive oxide species and protect activity of the sperms, and folacin can promote maturity of the sperms and improve functions of the sperms. The medicine is reasonable in composition, and the synergistic effect of various components is utilized, so that the medicine is remarkable and lasting in treatment effect, safe and reliable and convenient to take orally, and can effectively promote spermatogenesis, improve survival rate of the sperms and improve activity of the sperms.
Owner:梁晓会
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