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60 results about "Serious infection" patented technology
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Serious infections are caused by viruses, bacteria or fungi and can lead to serious medical situations unless treated. Below are a few infections that may require a visit to the emergency room.
Methods for predicting and treating infection-induced illnesses and predicting the severity of infection-induced illnesses
InactiveUS20130243794A1Reduce in quantityBiocideMicrobiological testing/measurementIncreased riskCvd risk
The invention provides methods for determining the propensity to develop, or the presence of, one or more infection-induced illness(es). The invention further provides methods of treating an infection (e.g., bacterial infection), methods of diagnosing an infection-induced illness in a subject, and methods of predicting the future severity of one or more infection-induced illness(es). Also provided are kits for determining the likelihood or propensity of a subject to develop one or more infection-induced illness(es) and kits for diagnosing one or more infection-induced illness(es) in a subject and identifying a subject as having an increased risk of later developing one or more severe infection-induced illness(es).
Owner:BETH ISRAEL DEACONESS MEDICAL CENT INC
Novel aminoglycoside antibiotics effective against methicillin resistant staphylococcus auerus (mrsas)
InactiveUS20070161581A1Great anti-microbial activitySignificant antimicrobial activityAntibacterial agentsBiocideMethicillin resistant StaphylococcusGlycoside
Disclosed are compounds represented by general formula (I) or pharmacologically acceptable salts or solvates thereof having excellent antimicrobial activity against bacteria causative of severe infections such as pneumonia and septicemia, particularly against MRSA, and also antimicrobial agents comprising these compounds, and pharmaceutical compositions comprising these compounds as an active component.
Owner:MEIJI SEIKA KAISHA LTD +1
Compsoite vitamin injection and its production
InactiveCN101073580AAchieving a co-solution problemReduce usageHydroxy compound active ingredientsMetabolism disorderSolubilityVitamin K2
The invention is concerned with compound vitamin injecting liquid and its produce method. This injecting liquid relates compound vitamin for adult and children and made of two bottles. The first bottle has vitamin C, vitamin A, vitamin D3, vitamin B1, vitamin B2, vitamin B6, niacinamide, dextrorotation panthenol, vitamin E, vitamin K and proper hydrotropic agent. The second bottle has folic acid, vitamin H and vitamin B12. The injecting liquid has same component in different dosage. The production is water-solubility injection with nice stability and safety. It can be diluted as common vitamin maintain agent. It can be used in vein for some conditions. The conditions relate to surgical, burn with large range, fracture and other trauma, serious infection illness and narcosis. Those conditions change the demand greatly and consume nutrition.
Owner:BEIJING RUNDEKANG MEDICAL TECH CO LTD
Wound Suture Capable of Identifying the Presence of Bacteria
InactiveUS20090142275A1Ultrasonic/sonic/infrasonic diagnosticsSuture equipmentsSurgical site infectionSolvatochromism
A wound suture containing a solvatochromatic indicator that undergoes a color change in the presence of bacteria often associated with surgical site infection is provided. Such a color change provides a “real time” indication of the onset of infection, which may alert medical staff to apply an appropriate antimicrobial treatment (e.g., antibiotic) to the patient (e.g., human or animal) before a more serious infection occurs. The patient may also be able to accurately monitor the condition of a wound after discharge from the hospital. Further, the lack of a color change may provide the medical staff or patient with the assurance that the area is generally free of infection and clean.
Owner:KIMBERLY-CLARK WORLDWIDE INC
Pharmaceutical composition for treatment of abnormal energy metabolism and application thereof
ActiveCN102058888ATo promote metabolismPromote recoveryOrganic active ingredientsNervous disorderDiseaseDiabetes mellitus
The invention relates to a pharmaceutical composition for the treatment of abnormal energy metabolism, which is the pharmaceutical composition containing a) a medicine for promoting fatty acid oxidation or derivatives thereof and b) a medicine for promoting glucose oxidation or pharmaceutical salts thereof. The pharmaceutical composition can comprehensively balance the metabolisms of fatty acid and glucose, optimize the productivity of fatty acid and glucose, reduce the jeopardy of abnormal aggregation of acidic metabolites, including free fatty acid or lactic acid and the like on organism, treat mitochondrial dysfunction, improve the defect that trimetazidine and the like are likely to create the accumulation of free fatty acid owing to the suppression on the fatty acid oxidation, and can be used for the auxiliary treatment for a plurality of diseases featured by imbalanced energy metabolism, such as acute and chronic ischemia, traumas, serious infection, diabetes, tumors, etc.
Owner:CHANGZHOU HI TECH DISTRICT MULTIPLE DIMENSION IND TECH INST
Natural fruit and vegetable preservative
InactiveCN1672535ASimple storage conditionsSimple Conditions of CarriageFruit and vegetables preservationSodium bicarbonateAdditive ingredient
The natural fruit and vegetable preservative is prepared through mixing lilac flower extract and adsorbent, which is bentonite and active carbon. The lilac flower extract is prepared with lilac flower and through crushing, water soaking, distilling to obtain distillate, the first extraction of the distillate with solvent, the second extraction of the supernatant with sodium bicarbonate, the third extraction of the second supernatant with sodium bicarbonate, and volatilizing the solvent in the lower layer to leave the lilac flower extract. Mixing bentonite and active carbon first and mixing with the lilac flower extract then can produce the fumigating fruit and vegetable preservative. The fruit and vegetable preservative has obvious and lasting inhibition on blue mold and Aspergillus niger with serious infection to cut of fruit and vegetable, has active effective period as long as 15 months, and may be used in preserve various kinds of fruits and vegetable.
Owner:CROPS BREEDING CULTIVATING INST SHANGHAI AGRI SCI ACAD
Numerical control system capable of performing real-time control on renal pelvis pressure in ureteroscopy based on sheath-side optical fiber pressure sensor monitoring
PendingCN109998698AAvoid inhalationIncrease the difficultyDiagnosticsSurgeryMain channelHigh pressure
The invention discloses a numerical control system capable of performing real-time control on renal pelvis pressure in ureteroscopy based on sheath-side optical fiber pressure sensor monitoring, whichcomprises an optical fiber pressure measuring system, an independent double-channel ureter leading-in sheath, a numerical control platform with a perfusion / attraction function and an intelligent terminal. In the system, a perfusion pump of a soft mirror connected with the numerical control platform enters a kidney through a main channel of the ureter leading-in sheath; an optical fiber pressure sensor enters a renal pelvis through a side channel to monitor the pressure of the renal pelvis, and both channels can be connected with negative pressure suction of the numerical control platform. According to the measured pressure feedback, the numerical control platform carries out data interaction with the intelligent terminal through wire / wireless; the intelligent terminal collects and analyzes the data in the operation, synchronously optimizes the working mode and can carry out later maintenance on the numerical control platform. The numerical control system has the advantages of real-time accurate pressure control, convenient adjustment and maintenance and the like, can effectively prevent complications such as kidney injury, serious infection and the like caused by high pressure inthe soft mirror operation, and improves the safety and the efficiency of the operation.
Owner:FUJIAN MEDICAL UNIV UNION HOSPITAL
Novel voriconazole broad-spectrum antifungal medicine compound, broad-spectrum antifungal medicine composition and application thereof
ActiveCN101575330ABroad and potent antifungal activityImprove mechanical propertiesOrganic active ingredientsAntimycoticsMonilinia laxaItraconazole
The invention relates to a novel broad-spectrum antifungal medicine compound, a broad-spectrum antifungal medicine composition, an application of the compound or the composition in the preparation of a broad-spectrum antifungal medicine, and an application of the compound or the composition in the preparation of a medicine used for treating severe invasive infection (comprising Candida krusei) caused by invasive aspergillosis and / or Fluconazole-resistant Monilia and / or severe infection caused by Scedosporium and fusarium. The novel broad-spectrum antifungal medicine compound and the broad-spectrum antifungal medicine composition have extensive and strong antifungal activity and better dynamic property and safety. For deep mycotic infection, the novel broad-spectrum antifungal medicine compound and the broad-spectrum antifungal medicine composition are better than the original voriconazole in the aspects of the antibiotic activity and the medicine resistance and is better than amphotericin B in the aspects of safety and effectiveness; and compared with the formerly applied voriconazole, Fluconazole, itraconazole and amphotericin B, the novel broad-spectrum antifungal medicine compound and the broad-spectrum antifungal medicine composition have reinforced medicine effect, less adverse reaction and good safety.
Owner:LIVZON PHARM GRP INC
Parenteral Combination Therapy For Infective Conditions With Drug Resistant Bacterium
InactiveUS20080188403A1Antibacterial agentsOrganic active ingredientsBacteroidesHospitalized patients
The invention describes a pharmaceutical composition to combat multiple-drug-resistant bacteria in non-ocular infective conditions. Compositions comprising glycopeptides, in particular vancomycin, and cephalosporins, in particular ceftriaxone, are disclosed. Such compositions are found to be useful for parenteral administration for hospitalized patients with serious infections. Specifically, this invention also discloses a pharmaceutical composition further including an excipient such as CVMC agent and is available in dry powder form for reconstitution before injection with a suitable solvent. The pharmaceutical compositions of this invention have been found normally to enhance resistance to precipitation in solutions to be administered parenterally. The invention also gives details of the dosage forms stored in sealed containers to be reconstituted before use. The invention further provides a process to manufacture these compositions and also a method of treating a subject having non-ocular infective conditions due to multi drug resistant bacterium.
Owner:VENUS REMEDIES LTD
Disposable safety syringe
A disposable safety syringe designed to prevent syringe handlers from being pricked by a needle by covering the needle with a needle shield, is provided. Special attention should be given to syringe needles because they are sharp enough to cause needle stick injuries before and after use. In particular, if a user is accidentally injured by a blood-stained needle, serious infections might be caused through the needle. Accordingly, the needle is covered with the needle shield after use. The needle shield is fitted over a syringe cylinder. A stopping tab prevents the needle shield from sliding off the cylinder. Inserting tabs are formed by cutting part of shield walls, and locking grooves are formed in the end of the inserting tabs. A fixing adapter has an engagement sill formed in the inner side thereof and a number of elastic fins in the outer side thereof, which is fitted on the locking tab of the needle fixer.
Owner:BANG SANG HYOK +1
Quaternary ammonium salt cationic antibacterial and antifouling coating layer as well as preparation method and application thereof
ActiveCN112552765AGood coating levelingGood compatibilityAntifouling/underwater paintsPaints with biocidesPolyethylene glycolIonic polymerization
The invention discloses a quaternary ammonium salt cationic antibacterial and antifouling coating layer as well as a preparation method and application thereof. The quaternary ammonium salt cation antibacterial and antifouling coating layer is arranged on the surface of a base material and comprises an outer-layer polyethylene glycol structure and an inner-layer quaternary ammonium salt cationic polymer structure; the polyethylene glycol structure and the quaternary ammonium salt cationic polymer structure are combined together through a Schiff base structure to form a polymer brush with a layered structure. Therefore, under the condition of normal or slight infection, the outer-layer polyethylene glycol structure can effectively inhibit adhesion of bacteria, and when serious infection occurs, the bacteria can secrete acidic substances to cause Schiff base breakage, so that the inner-layer quaternary ammonium salt cationic polymer structure is exposed to kill the bacteria and inhibit infection. The preparation method of the quaternary ammonium salt cationic antibacterial and antifouling coating layer is simple and safe, the solution stability is good, and the quaternary ammonium salt cationic antibacterial and antifouling coating layer has a long-acting antibacterial antifouling function and can be widely applied to the fields of bioengineering and biomedicine.
Owner:JIANGNAN UNIV
Antibiotic Combinations For Providing Total Solution to the Treatment of Infections
InactiveUS20090318378A1Improve efficacyImprove securityAntibacterial agentsBiocideHospitalized patientsNosocomial pneumonias
The invention relates to a new pharmaceutical composition, a method of treatment of infection and also a process to prepare the composition. The infectious complications are important causes of morbidity and mortality. Hospital acquired pneumonia (HAP) remains the most severe nosocomial infection in intensive care units. Beta-lactams alone are always considered inadequate when P. aeruginosa and / or methicillin-resistant S. aureus are implicated as pathogens or copathognes. The present invention provides the desired empirical therapy for control of all bacterial infections. The invention provides antibiotic combination products for delivering at least two different antibiotics, through parenteral dosage form comprising protein-synthesis-inhibiting antibiotic which is amikacin or its sulphate salt and non-protein-synthesis-inhibiting antibiotic which is cefepime or its hydrochloride salt. The invention provides a total solution, against multiresistant P. aeruginosa, or Acinetobacter spp. and / or methicillin-resistant S. aureus, and are useful for intramuscular or intravenous administration as antibiotics for hospitalized patients with acute or serious infections. The pharmaceutical compositions described here normally have the least nephrotoxicity and have better efficacy and safety of cefepime plus amikacin combination.
Owner:VENUS REMEDIES LTD
Multifunctional nursing device for patient with serious infection
PendingCN108042328AImprove self-care abilityRaise belief in recoveryWheelchairs/patient conveyanceSuction-kneading massageMassagePediatrics
Owner:THE FIRST AFFILIATED HOSPITAL OF ZHENGZHOU UNIV
Implanted Medical Driveline Strain Relief Device
The strain relief device of this invention reduces injury and danger of serious infection at driveline skin exit sites caused by routine patient activities and accidental stresses on the drivelines of ventricle assist devices and similar externally powered implanted medical devices. The device comprises a sleeve that forms an adherent biological interface with the skin and compliant seals between the sleeve and driveline. The compliant seals mechanically decouple linear and rotary driveline motions from the sleeve, while isolating the patients internal tissue from the outside environment. This mechanical decoupling reduces stresses and injury to the adherent interface, thereby reducing the risk of bacterial entry and infection. The device may be inserted into the patient as part of the driveline assembly implantation procedure, and is positioned such that the skin contacts and adheres to the outer diameter of the sleeve. It may also be partially or completely replaced or retrofitted to previously implanted drivelines in a relatively simple procedure.
Owner:MEACHAM G B KIRBY
Disposable safety syringe
A disposable safety syringe designed to prevent syringe handlers from being pricked by a needle by covering the needle with a needle shield, is provided. Special attention should be given to syringe needles because they are sharp enough to cause needle stick injuries before and after use. In particular, if a user is accidentally injured by a blood-stained needle, serious infections might be caused through the needle. Accordingly, the needle is covered with the needle shield after use. The needle shield is fitted over a syringe cylinder. A stopping tab prevents the needle shield from sliding off the cylinder. Inserting tabs are formed by cutting part of shield walls, and locking grooves are formed in the end of the inserting tabs. A fixing adapter has an engagement sill formed in the inner side thereof and a number of elastic fins in the outer side thereof, which is fitted on the locking tab of the needle fixer.
Owner:BANG SANG HYOK +1
Bacteria resisting medicine of erythrocin nanometer-emulsion and the preparing method
InactiveCN101032507AReduce energy consumptionImprove securityAntibacterial agentsOrganic active ingredientsPenicillinSide effect
The nanometer antibacterial erythromycin medicine consists of erythromycin in 0.5-1.5 wt% and nanometer emulsion matrix in 98.5-99.5 wt%. It is yellowish transparent liquid, and has medicine granularity of 1-100 nm, low viscosity, high stability, fast absorption, targeted medicine release, high bioavailability, less toxic side effect and other features. The medicine may be attached well onto bacteria and permeated into bacteria to disturb their metabolism and to reach bacteriostasis and bactericidal effect. It is used mainly for treating serious infection caused by penicillin resisting staphylococcus aureus and hemolytic streptococcus as well as chicken's chronic respiratory tract disease, malignant rhinitis, etc. The medicine has simple preparation process, less toxicity and high safety.
Owner:NORTHWEST A & F UNIV
Prevention and/or treatment of multiple organ dysfunction syndrome with interleukin-22
ActiveUS20110268696A1Antibacterial agentsPeptide/protein ingredientsWhite blood cellEmergency medical services
The present invention relates to use an agent for the prevention and / or treatment of multiple organ dysfunction syndrome (MODS) or multiple organ failure (MOF) comprising interleukin-22 (IL-22) as an effective ingredient. The present invention is applicable to prevention of or therapy for diseases from sepsis, septic shock, liver failure, to multiple organ dysfunction syndromes. More particularly, the present invention is useful for an emergency medical service, for treatment of injury caused by a traffic accident, burns, heat attacks, hypercytokinemia or severe infective diseases.
Owner:GENERON (SHANGHAI) CORP LTD
Traditional Chinese medicine preparation for preventing and treating bone marrow suppression after radiotherapy and chemotherapy
ActiveCN105435206AImprove clinical symptomsNo obvious side effectsGranular deliveryBlood disorderSide effectWhite blood cell
The invention relates to a traditional Chinese medicine preparation for preventing and treating bone marrow suppression after radiotherapy and chemotherapy. The traditional Chinese medicine preparation is prepared from, by weight, 10-20 parts of codonopsis pilosula, 15-60 parts of astragali radix, 15-20 parts of fructus ligustri lucidi, 10-20 parts of eclipta alba, 15-30 parts of caulis spatholobi, 10-30 parts of peanut coat, 10-20 parts of rhizoma polygonati, 6-10 parts of ginger and 10-15 parts of radix bupleuri. The traditional Chinese medicine preparation has the advantages of good curative effect and low cost, has the curative effect similar to GM-CsF on the aspect of leukopenia (including severe bone marrow suppression) after radiotherapy and chemotherapy, can improve the clinical symptoms, has no obvious side effect, and meanwhile can effectively improve blood platelet and hemoglobin values and effectively prevent adverse consequences, such as serious infection and fever caused by leukocyte decrease.
Owner:朱晓婷
Prevention and/or treatment of multiple organ dysfunction syndrome with interleukin-22
ActiveUS8956605B2Antibacterial agentsPeptide/protein ingredientsWhite blood cellEmergency medical services
The present invention relates to use an agent for the prevention and / or treatment of multiple organ dysfunction syndrome (MODS) or multiple organ failure (MOF) comprising interleukin-22 (IL-22) as an effective ingredient. The present invention is applicable to prevention of or therapy for diseases from sepsis, septic shock, liver failure, to multiple organ dysfunction syndromes. More particularly, the present invention is useful for an emergency medical service, for treatment of injury caused by a traffic accident, burns, heat attacks, hypercytokinemia or severe infective diseases.
Owner:GENERON (SHANGHAI) CORP LTD
Device for diagnosing tissue injury
The device for diagnosing tissue injury of the invention has a catheter insertable into the body and a radical sensor provided in the catheter, and is characterized in that the radical sensor has a sensor electrode capable of measuring superoxide anion radicals provided at a tip end of the catheter, a lead wire connector for a sensor provided at a basal portion of the catheter, and a lead wire for a sensor for connecting the sensor electrode portion to the lead wire connector for a sensor. With the device, in vivo free radicals typified by superoxide anions in systemic organ or tissue injury caused by cerebral ischemia reperfusion injury, severe infection or sepsis can be promptly and quantitatively monitored, and whether the in vivo tissue conditions are good or not can be accurately diagnosed.
Owner:YUASA MAKOTO +3
Cytokines as prognostic markers of respiratory-tract infection following major surgery
InactiveUS20120129176A1Reduces and excludes variationHigh riskHealth-index calculationMicrobiological testing/measurementFactor iiPre operative
The invention relates to the use of a certain subset of cytokine markers as prognostic variables of infection status in an individual, and especially as prognostic markers of a patients developing severe infection such as pneumonia, and respiratory tract infection following surgery. The subset of cytokine markers consists of the interleukin cytokines IL-2, IL-7, IL-23, IL-27, and IL-IO, and Interferon-γ (INFγ) and Tissue Necrosis Factor-α (TNFα). The markers may be employed as individual prognostic variables of infection status, or they may be used in pairs or other combinations. Generally, the abundance of the markers is correlated with infection status by means of an absolute pre-operative value of biomarker abundance, ratio's of pre-operative to post-operative biomarker abundance, or ratio values for pairs of certain biomarkers within the subset. Typically, cytokine abundance is expressed in terms of mRNA copy number wherein the copy numbers are ideally normalised to a house keeping gene and quantification of mRNA copy number is determined by RT-PCR containing reference serial dilutions of cytokine specific cDNA.
Owner:THE PROVOST FELLOWS & SCHOLARS OF THE COLLEGE
Soluble microbial additive capable of improving immunity of laying hens and preparation method thereof
InactiveCN106615952AImprove immunityImprove gut microbiome balanceAnimal feeding stuffAccessory food factorsPhytaseVitamin C
The invention discloses a soluble microbial additive capable of improving immunity of laying hens. The soluble microbial additive comprises a compound microbial agent, vitamin C, phytase and a compound enzyme preparation, wherein the compound microbial agent is a mixed culture solution of bacillus coagulans and bacillus subtilis. After the microbial additive is directly fed to the laying hens, the microbial additive can achieve beneficial influence on the laying hens by improving the intestinal microbial balance and can replace antibiotics to maintain the intestinal health; meanwhile, when the microbial additive is applied to the laying hens after the laying hens with serious infection are treated by antibiotics, the intestinal flora damaged by the antibiotics can be restored.
Owner:SHANGHAI CHUANGBO ECOLOGICAL ENG
Cytokines as prognostic markers of respiratory-tract infection following major surgery
InactiveUS20150197808A1Reduce riskHigh riskHealth-index calculationMicrobiological testing/measurementInterferon alphaPre operative
The invention relates to the use of a certain subset of cytokine markers as prognostic variables of infection status in an individual, and especially as prognostic markers of a patients developing severe infection such as pneumonia, and respiratory tract infection following surgery. The subset of cytokine markers consists of the interleukin cytokines IL-2, IL-7, IL-23, IL-27, and IL-10, and Interferon-γ (INFγ) and Tissue Necrosis Factor-α (TNFα). The markers may be employed as individual prognostic variables of infection status, or they may be used in pairs or other combinations. Generally, the abundance of the markers is correlated with infection status by means of an absolute pre-operative value of biomarker abundance, ratio's of pre-operative to post-operative biomarker abundance, or ratio values for pairs of certain biomarkers within the subset. Typically, cytokine abundance is expressed in terms of mRNA copy number wherein the copy numbers are ideally normalised to a house keeping gene and quantification of mRNA copy number is determined by RT-PCR containing reference serial dilutions of cytokine specific cDNA.
Owner:TRINITY COLLEGE DUBLIN
Extraction process of plant mildew-proof preservative
InactiveCN1672536AInfectiousEnhanced inhibitory effectFruit and vegetables preservationSodium bicarbonateWater vapor
Owner:CROPS BREEDING CULTIVATING INST SHANGHAI AGRI SCI ACAD
Intelligent dressing and preparation method thereof
ActiveCN110960352AReal-time monitoring of pH changesAvoid serious infectionsAdhesive dressingsAbsorbent padsWound dressingBiomedical engineering
The invention provides an intelligent dressing. The intelligent dressing comprises a transparent dressing patch, a pH sensor unit which is fixed on the transparent dressing patch, and a wound contactdressing which covers the pH sensor unit. The pH sensor unit is formed by blending dye-loaded silicon dioxide nanoparticles with alginate and polyoxyethylene and then carrying out electrostatic spinning. Compared with the prior art, the intelligent dressing provided by the invention has the advantages that nanometer encapsulation of a dye is realized through the silicon dioxide nanoparticles loaded with the dye; the pH sensor unit is obtained; on the basis that the wound nursing requirement is met, the pH change of a wound can be monitored in real time; infection information of the wound can be fed back; rapid and timely treatment can be easily adopted; serious infection of the wound is avoided; and good application prospects are achieved in the aspect of wound dressing.
Owner:河南驼人医疗器械研究院有限公司
Disposable safety syringe
InactiveUS20080051725A1Eliminate concernsInfusion syringesInfusion needlesBlood stainedSyringe needle
Owner:BANG SANG HYOK +1
Preparation method and applications of porcine circovirus type II recombinant lactobacillus plantarum oral vaccine
InactiveCN106520817AReduce stressReduce morbidityBacteriaViral antigen ingredientsVisceral organDiarrhea
The invention provides a preparation method of porcine circovirus type II recombinant lactobacillus plantarum. The preparation method comprises following steps: separated Cap sequence is connected with expression vector pPSCPSP so as to construct expression plasmid pPSCPSP-Cap; expression plasmid pPSCPSP-Cap is inserted into lactobacillus plantarum LP-1 so as to obtain porcine circovirus recombinant lactobacillus plantarum pPSCPSP-Cap-LP-1; a cultured product of pPSCPSP-Cap-LP-1 can be applied directly as an oral vaccine to stimulate bodies to generate antibodies effectively, and reduce the morbidity of porcine circovirus type II obviously. Application of the oral vaccine is beneficial for avoiding of retarded growth, emaciation, sow reproduction disorder, dyspnea, occasionally induced jaundice, diarrhea, extensive pathological changes of visceral organs and skin caused by serious infection of porcine circovirus in livestock breeding, improving of pig herd immunity and health conditions, and increasing of the economic benefit of breeding.
Owner:GUANGZHOU WELLTECH BIOTECH CO LTD
Application of recombination FN polypeptide in preparing medicine for treating severe infectious diseases such as septicemia
InactiveCN101121018AReduce mortalityAvoid damageAntibacterial agentsSaccharide peptide ingredientsDiseaseDisseminated coagulopathy
The invention discloses an N-terminal heparin binding domain polypeptide and a C-terminal binding domain polypeptide of a recombinant fibronectin. The N-terminal heparin binding domain polypeptide consists of five I-type homologous structures of the N-terminal of a FN molecule, including 237 aminophenols, which are from Ser46 to Gly282. A DNA sequence which codes the polypeptide is from 403bp to 1113bp with a length of 711bp. A FCR amplified fragment length is 741bp; a fragment length after double digestion is 729bp. A polypeptide molecular weight, which is expressed by barm, is 28.52kDa. The C-terminal heparin binding domain polypeptide consists of three III-type homologous structures of the FN molecule, including 272 aminophenols, which are from Tyr1720 to Tyr1991. The DNA sequence which codes the polypeptide is from 5428bp to 6244bp with a length of 816bp. The FCR amplified fragment length is 835bp; the fragment length after double digestion is 828bp. The polypeptide molecular weight, which is expressed by barm, is 36.09kDa. The invention is applied to medicine preparations for a serious infection of septicemia, a hemorrhage of thrombocytopenia and a disseminated intravascular coagulation.
Owner:FUJIAN MEDICAL UNIV UNION HOSPITAL
Air purifying system for protective clothing
InactiveCN1488411ANo flow phenomenonAvoid pollutionChemical protectionHeat protectionSiphonElectric machine
The invention discloses an air-purifying system of exposure suit, including power supply, electric machine, fan, shield, filter bag and also siphon. The fan is connected with the electric machine and set in the siphon, the electric machine connected with the power supply through wires, the shield set on one end of the siphon, the filter bag set on the other end, and the filter composed of at least of one of filtering, inactivating and absorbing layers. It can be set on one-piece exposure suit, the air vent set on the exposure suit, and it uses the micro-fan to blow the processed fresh air into the exposure suit for people to breathe, achieving the purpose to protect and reduce temperature, and preventing serious infection like SARS, able to be used as Chemical protective clothing and fire clothing.
Owner:TIANJIN UNIV
Devices and Methods for Determining the Risk of Developing a Serious Infection
InactiveUS20140335546A1Great riskBioreactor/fermenter combinationsBiological substance pretreatmentsProgram instructionDisplay device
A device for calculating risk of a patient developing a serious infection, the device comprising: a controller; storage storing electronic program instructions for controlling the controller; a display for displaying a user interface; and input means; wherein the controller is operable, under control of the electronic program instructions, to: receive input via the input means, the input comprising one or more values representing respective measures of one or more risk factors associated with biological sample(s) obtained from the patient; process the input to calculate the risk; and display an indication of the calculated risk via the display.
Owner:G J CARROLL
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