33results about How to "Increase energy metabolism" patented technology

The invention provides methods for one or more of enhancing energy metabolism, promoting healthy energy metabolism, maintaining healthy energy metabolism, preventing conditions that result in a decline or deficiency in energy metabolism, treating conditions that result in a decline or deficiency in energy metabolism, and preventing the accumulation of excess body fat in animals without reducing energy intake by the animals. The methods comprise administering isoflavones to the animals, preferably in amounts of from about 0.001 to about 10 g / kg / day.

The present invention provides for compositions, methods and kits for regulating energy metabolism. In one aspect, the invention provides for compositions that comprise a combination of (a) branched chain amino acids, such as leucine, and (b) vitamin B6, or any precursors or metabolites of (a) or (b). These combinations may be synergistic and / or effective for reducing weight or adipose volume. In another aspect, the invention provides for methods of regulating energy metabolism by the administration of one or more compositions comprising branched chain amino acids and vitamin B6. The invention also provides for kits comprising compositions of branched chain amino acids and vitamin B6 packaged in an oral dose form with usage instructions.

The invention relates to a production method of bacillus amyloliquefaciens antimicrobial lipopeptide and application thereof in prawn feeds and belongs to the technical fields of aquiculture and biology in the field of agriculture. The production method comprises the following steps that bacillus amyloliquefaciens fmb-50 with the collection number of CGMCC No.6249 is used as a strain and is sequentially subjected to seed culture, amplification culture and fermentation production to obtain fermentation liquor; the thalli of the fermentation liquor are removed through microfiltration or membrane filtration and nanofiltration; corn starch or porous starch is added for absorption and spray drying is carried out, thus obtaining an antibacterial substance feed additive with the antibacterial valence of 40000-50000 IU / g or 250000 IU / g. The antibacterial substance which is produced from the bacillus amyloliquefaciens fmb-50 through fermentation can be industrially produced in a large scale; the production period is short and production cost is greatly reduced; when used in the prawn feeds, the antibacterial substance can reduce the mortality rate, improve the utilization ratio of the prawn feeds, promote the nonspecific immunoreaction of prawns and enhance the energy metabolism level.

The invention discloses an integrated system for solar-driven microbial electrolysis cell strengthening treatment on rural domestic sewage. In the system, the integrated device comprises an anaerobic tank, a facultative tank, an aerobic tank and a secondary sedimentation tank. Each two zones are separated by a stainless steel plate and the stainless steel plates are communicated at intervals from top to bottom. The bottom of the anaerobic tank is provided with a water inlet. The top of the sedimentation tank is provided with a water outlet. An aeration head is arranged in the aerobic tank and is connected to an air pump. A guide plate and a mud guard are arranged in the secondary sedimentation tank. A sludge outlet of the secondary sedimentation tank is connected to a sludge flowing direction inlet of the aerobic tank by a sludge reflux pump. An anode carbon felt is arranged in the anaerobic tank. A cathode carbon felt is arranged in the aerobic tank. An anode and a cathode are connected to a storage battery by stainless steel wires. A solar cell panel provides powder for the storage battery. The integrated system greatly improves the original biological treatment technology, reduces an operation cost by natural solar energy and provides a novel rural domestic sewage treatment technology.

A nutritional composition for the treatment of syndromes related to dysfunctional energy metabolism is provided. The composition comprises a combination of L-carnitine, acetyl-L-carnitine, pantothenate and niacinamide. Methods of treatment of dysfunctional energy metabolism are also disclosed.

The process of setting up cell membrane solid phase chromatographic model for screening active platelet aggregation components from Chinese medicine includes the following steps: establishing the fingerprint of ginger oleoresin solution as the Chinese medicine to be screened, separating chicken platelet suspension, immobilizing the effective component of ginger oleoresin solution with the platelet cell membrane, eluting the uncombined components, dissociating the platelet immobilized the effective component of ginger oleoresin, and the HPLC analysis of the dissociated solution of platelet immobilized effective component. The present invention has rich material source, low cost and excellent application foreground.

The invention discloses a preparation method of a maca extract. The preparation method comprises the following steps of: cleaning and draining off maca and grinding the maca into powder; adding a methanol solution, water and concentrated hydrochloric acid and carrying out ultrasonic treatment to obtain a crude extract solution; concentrating the crude extract solution in the step (2) until no alcohol taste exits, thereby obtaining a concentrated crude extract; adsorbing the concentrated crude extract in the step (3) with macroporous resin; eluting the macroporous resin according to the order of one column volume of water, three column volumes of 20% ethanol, four column volumes of 50% ethanol, three column volumes of 75% ethanol and one column volume of 95% ethanol, and collecting an eluent; and carrying out ultralow-temperature freeze drying treatment on the eluent which is obtained by the third column volume of 20% ethanol and three column volumes of 50% ethanol, thereby obtaining the maca extract. The maca extract prepared by the method is obvious in cell ATP concentration increase effect and high in effective ingredient purity; the method is simple to operate, low in cost and suitable for massive production.

The invention discloses a solid medium used for cornea model low temperature preservation and a preparation method and an application method thereof. The solid medium is prepared by a basic medium and an agarose aqueous solution according to the volume ratio of 1:1 by steps of uniform mixing and coagulation; the mass concentration of the agarose aqueous solution is 0.5-5%; the basic medium takes a mixed solution of a DMEM nutrient solution and a F12 nutrient solution as a basic solution, fetal calf serum, retinoic acid, human epidermal growth factor, insulin, hydrocortisone, adenine, triiodothyronine, glutamine and a low temperature protective agent are added; the low temperature protective agent is a mixture of HEPES, cane sugar, glycine, alanine, adenosine, vitamin E, vitamin C, hyaluronic acid and chondroitin sulfate. The solid medium has the advantage of reducing low temperature anoxic damage on histocyte, can effectively guarantee the accuracy of the test result of a cornea model, and has the advantages of convenient operation and long-distance transport.

The invention provides a low-temperature preservation and transportation culture medium. The low-temperature preservation and transportation culture medium comprises the following components: a melanin skin model culture solution, a buffer system, agarose, sucrose, glycine, adenosine, alpha-tocopherol, vitamin C, sphingosine-1-phosphoric acid, Y-27632 and heparin, wherein the melanin skin model culture solution comprises a basic culture solution, hydrocortisone, insulin, growth factors, epinephrine, 12-myristic acid-13-phorbol acetate, stem cell factors, glutamine, calcium chloride and antibiotics.

The invention discloses a fat management composition, a preparation method and an application. The fat management composition consists of the following components in parts by weight: 12-20 parts of L-carnitine, 11-20 parts of tea saponin, 5-11 parts of chitosan, 3-8 parts of anthocyanin, 1-3 parts of a bamboo leaf extract and 1-6 parts of limonin. The product (the fat management composition) provided by the invention, which is prepared from the L-carnitine, the tea saponin, the chitosan, the anthocyanin, the bamboo leaf extract and the limonin, has functions of promoting fat metabolism, improving a cell energy metabolic rate and inhibiting fat formation, and in addition, an effect of reducing weight can be also achieved; and the preparation method is simple and is beneficial for achievingindustrial production.

The invention discloses a composition for preventing and controlling cold damage, food containing the composition and an application of the composition or the food, and belongs to the technical fieldof food production. The composition is prepared from [6]-gingerol, piperine and cinnamaldehyde; and the food containing the composition is used to prepare a beverage preparation, and the beverage preparation includes the following components: 2 parts by mass of the [6]-gingerol, 1.6 parts by mass of the piperine, 1.0 part by mass of the cinnamaldehyde, 0.4 part by mass of pectin, 0.3 part by massof sodium carboxymethyl cellulose, 0.05 parts by mass of citric acid, 0.04 part by mass of aspartame and 1000 parts by mass of purified water. The composition provided by the invention does not contain toxic ingredients, can better increase the body heat-generating effect, and can be used to prevent and treat the cold damage; and the components have a synergistic effect, so that the use amount ofa drug is reduced, and the problems that a current drug for preventing and treating cold damage contains multiple medicine flavors, a large dosage and toxic ingredients are solved.

The invention provides an application and using method of cornflower-3-oxo-glucoside in medicines for treating obesity and obesity-related diseases and improving energy metabolism or promoting pyrexia. Meanwhile, the invention also provides a medicine for treating obesity and obesity-related diseases and improving energy metabolism or promoting pyrexia, wherein the medicine comprises the cornflower-3-oxo-glucoside. The test proves that the cornflower-3-oxo-glucoside can effectively inhibit obesity of db / db model mice and improve insulin resistance of the db / db model mice. The adaptability of an organism on cold stimulation is improved by increasing the energy metabolism level of the organism, improving the glucose tolerance of the organism, enhancing insulin sensitivity of tissues and activating heat production of the organism, and a novel way is developed for treatment of the obesity and related diseases.

The invention relates to a production method of bacillus amyloliquefaciens antibacterial lipopeptide and its application in prawn feed, belonging to the technical field of aquaculture and the field of biotechnology in the agricultural field. Bacillus amyloliquefaciens fmb-50 with the preservation number CGMCC No.6249 is used as the strain, and the fermentation liquid is obtained through seed cultivation, expanded cultivation and fermentation production in sequence; the fermentation liquid is removed by microfiltration or membrane filtration and nanofiltration, Corn starch or porous starch is added for adsorption and spray-dried so that the antibacterial potency of the antibacterial substance feed additive is 40,000-50,000 IU or 250,000 IU / g. The present invention uses Bacillus amyloliquefaciens fmb-50 as raw material to ferment and produce antibacterial substances, which can be produced in a large-scale industrialized manner, has a short production cycle and greatly reduces production costs, and can be used in prawn feed to reduce mortality and improve the feed utilization rate of prawns. Promote non-specific immune response and improve energy metabolism in prawns.

The invention provides an application of an angiotensin converting enzyme inhibitor, and in particular relates to the application of the angiotensin converting enzyme inhibitor in preparing medicine for treating obesity, obesity related diseases, improving energy metabolism or promoting heat generating. The experiment proves that the angiotensin converting enzyme inhibitor fosinopril treatment is capable of effectively inhibiting the obesity induced by high fat diet, treating insulin resistance induced by the high fat diet, improving the glucose tolerance dose of the organism by increasing the energy metabolism level of the organism, enhancing the insulin sensitivity of the tissue, and enhancing the adaptability of the organism to cold excitation by activating the organism to generate heat; and a new path for treating the obesity and related diseases is developed.

Disclosed is an injection for treating coronary heart disease and cerebral infarction which is prepared from the raw material (by weight ratio) of notoginseng 70-30%, haw leaf 30-70% through the conventional preparing processes. The injection may also contains mannitol as the adjuvant.

The invention relates to a new application of a compound Compound C, which is the application of the compound Compound C in the preparation of a medicament for promoting the expression of adipocyte UCP1. The browning of adipocytes is promoted, that is, the expression of brown adipocytes marker gene uncoupling protein 1 (UCP1) is enhanced, excess fat can be effectively consumed in the form of calories, glucose uptake and fatty acid oxidation can be promoted, the number and vitality of mitochondria can be improved, and the levels of glucose and lipid metabolism and energy metabolism in the bodycan be enhanced, thereby effectively treating fatty liver, impaired glucose tolerance, insulin resistance and type 2 diabetes. Therefore, the compound Compound C has an effect of promoting the expression of the adipocyte UCP1, and can effectively prevent and treat the fatty liver, the impaired glucose tolerance, the insulin resistanceand the type 2 diabetes.

The invention discloses edible energy chopsticks. The preparation method comprises the steps that cudrania tricuspidata leaf extracts are prepared, ingredients are mixed uniformly, pulped and poured in a mold, and the ingredients are subjected to baking molding through an oven; the invention further discloses application of the cudrania tricuspidata leaf extracts to the preparation of anti-depression medicines and nervous excitation promotion medicines. The edible energy chopsticks have the advantages that the energy bar effect is achieved, the chopsticks are environmentally friendly, the effect is significant, the idea is novel, the chopsticks can be used for multiple purposes, the cost is low, no side effects are involved, and the energy chopsticks are applicable to large-scale popularization and production.

The invention relates to a capsule for treating diabetic coronary heart disease wherein the formulation comprises the following constituents, gen-seng, lilyturf root, schisandra fruit, astragalus root, rhizoma dioscoreae, atractylodes rhizome, scrophularia root, goldthread root, kudzu vine root, root of red rooted saliva, haw, dried rehmannia root, root of Chinese trichosannthes, radix paeoniae rubrathe, dalbergia wood, boneol, atractylodes rhizome, dalbergia wood and schisandra fruit.

The invention discloses a solid medium used for cornea model low temperature preservation and a preparation method and an application method thereof. The solid medium is prepared by a basic medium and an agarose aqueous solution according to the volume ratio of 1:1 by steps of uniform mixing and coagulation; the mass concentration of the agarose aqueous solution is 0.5-5%; the basic medium takes a mixed solution of a DMEM nutrient solution and a F12 nutrient solution as a basic solution, fetal calf serum, retinoic acid, human epidermal growth factor, insulin, hydrocortisone, adenine, triiodothyronine, glutamine and a low temperature protective agent are added; the low temperature protective agent is a mixture of HEPES, cane sugar, glycine, alanine, adenosine, vitamin E, vitamin C, hyaluronic acid and chondroitin sulfate. The solid medium has the advantage of reducing low temperature anoxic damage on histocyte, can effectively guarantee the accuracy of the test result of a cornea model, and has the advantages of convenient operation and long-distance transport.

The invention discloses an integrated system for solar-driven microbial electrolysis cell strengthening treatment on rural domestic sewage. In the system, the integrated device comprises an anaerobic tank, a facultative tank, an aerobic tank and a secondary sedimentation tank. Each two zones are separated by a stainless steel plate and the stainless steel plates are communicated at intervals from top to bottom. The bottom of the anaerobic tank is provided with a water inlet. The top of the sedimentation tank is provided with a water outlet. An aeration head is arranged in the aerobic tank and is connected to an air pump. A guide plate and a mud guard are arranged in the secondary sedimentation tank. A sludge outlet of the secondary sedimentation tank is connected to a sludge flowing direction inlet of the aerobic tank by a sludge reflux pump. An anode carbon felt is arranged in the anaerobic tank. A cathode carbon felt is arranged in the aerobic tank. An anode and a cathode are connected to a storage battery by stainless steel wires. A solar cell panel provides powder for the storage battery. The integrated system greatly improves the original biological treatment technology, reduces an operation cost by natural solar energy and provides a novel rural domestic sewage treatment technology.

The invention relates to a body weight management formula for enhancing fat metabolism. The formula comprises 3-6% of L-carnitin, 0.05-0.15% of synephrine and 0.025-0.075% of burdock. The formula is mainly used for promoting fat metabolism, and realizes a weight reduction effect through a fat formation inhibition mechanism by improving the energy metabolic rate of cells.

The invention belongs to the technical field of medicine and pharmacology, and particularly relates to an application of a nitric oxide spin trapping type nano targeting antioxidant capable of targeting liver mitochondria in preparation of a medicine for preventing diabetes mellitus. The nano targeting antioxidant provided by the invention can obviously inhibit the increase of glucose tolerance of diabetic mice, inhibit the increase of gluconeogenesis ability of the diabetic mice, and prevent the occurrence and development of diabetes mellitus by up-regulating expression of liver antioxidant protein, increasing mitochondrial generation of mice liver and improving mitochondrial energy metabolism function. Therefore, the nano antioxidant can be used for preparing medicines or health-care products for preventing diabetes mellitus.

The invention belongs to the technical field of additives, and discloses an additive for regulating the heart function of animals in high-altitude areas, and the effective component of the additive for regulating the heart function of animals in high-altitude areas is echinacea extract-chicoric acid; the content of chicoric acid is 4%, and the chicoric acid is yellow green fine powder and comprises 2-2.2% of chicoric acid, 1-1.5% of caffeic acid, 0.5-1% of chlorogenic acid and 0.3-0.5% of echinacea glycoside; the method for verifying the chicoric acid as the additive for regulating the heart functions of the animals in the high-altitude areas comprises the following steps: preparing a reagent; carrying out cell culture and grouping; determining oxidative damage level related enzyme activity; related inflammatory factor indexes are measured; determining related indexes of energy metabolism; and carrying out data processing. Results show that the chicoric acid improves the oxidation resistance of myocardial cells of H9c2 rats under hypoxia induction, reduces secretion of inflammatory factors and increases the energy metabolism rate.

The process of setting up cell membrane solid phase chromatographic model for screening active platelet aggregation components from Chinese medicine includes the following steps: establishing the fingerprint of ginger oleoresin solution as the Chinese medicine to be screened, separating chicken platelet suspension, immobilizing the effective component of ginger oleoresin solution with the platelet cell membrane, eluting the uncombined components, dissociating the platelet immobilized the effective component of ginger oleoresin, and the HPLC analysis of the dissociated solution of platelet immobilized effective component. The present invention has rich material source, low cost and excellent application foreground.

Provided are uses of human Nectin-2 protein. Nectin-2 protein, derived protein thereof or modified protein thereof can effectively inhibit obesity and diabetes, and are also used to treat obesity-related diseases including hypertension, and hyperlipemia, etc. The Nectin-2 protein not only reduces blood glucose, but also improves the body glucose metabolism, and enhances sensitivity to tissue insulin by improving energy metabolism of the body, and improves adaptability to cold stimulation by activating fatty acid metabolism of the body.

The invention discloses application of colla corii asini bone-strengthening oral liquid to prevention and / or treatment of anemia, and belongs to the technical field of medicines, and the anemia comprises iron-deficiency anemia, renal anemia and myelosuppression anemia. The colla corii asini bone strengthening oral liquid can increase erythrocyte count, hemoglobin concentration, hematocrit, erythrocyte average hemoglobin amount, erythrocyte average hemoglobin concentration and / or erythrocyte average volume; the serum iron content is increased; a transporter divalent metal transporter and a membrane iron transporter are increased; the intestinal iron absorption is promoted. The composition specifically comprises urea nitrogen and creatinine; related indexes of renal anemia are improved; the immune index of renal anemia can be improved. The percentage of leukocytes and lymphocytes of anemia caused by myelosuppression can be recovered; the hemoglobin content is increased; the number of macrophage colony stimulating factors and / or bone marrow cells in serum is increased; the immunocompetence is improved; the proliferation of lymphoid B cells and macrophages is promoted.