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44results about How to "Altered function" patented technology

Therapeutic delivery compositions and methods of use thereof

InactiveUS20020128218A1Reduce deliveryFacilitate transmission and introductionBiocidePeptide/protein ingredientsHydrophileNucleic acid sequencing
The present invention relates to compositions and methods for treating infectious diseases and genetic disorders through gene therapy and intracellular delivery of antisense oligonucleotides or other nucleic acid sequences. The present invention comprises a therapeutic delivery composition effective for treating a disease state comprising an administerable admixture of an effective amount of a therapeutic compound capable of altering nucleic acid sequence function and an effective amount of a block copolymer having the following general formula: 1 wherein: the mean aggregate molecular weight of the portion of the octablock copolymer represented by polyoxypropylene is between about 5000 and about 7000 Daltons; a is a number such that the portion represented by polyoxyethylene constitutes between about 10% to about 40% of the compound by weight; and b is a number such that the polyoxypropylene portion of the total molecular weight of the octablock copolymer constitutes between about 60% and about 90% of the compound by weight. The present invention also includes compositions and methods using biologically active nonionic reverse block copolymers. The reverse copolymers have an inner core of polyoxypropylene (POP) that is flanked on either end by polyoxyethylene (POE). The reverse block copolymers have the following formula: 2 wherein "b" represents a number such that the molecular weight of the hydrophobe (C.sub.3H.sub.6O).sub.b is between approximately 2,000 and 10,000, and "a" represents a number such that the percentage of hydrophile (C.sub.2H.sub.4O).sub.a is between approximately 5% and 30%.
Owner:EMANUELE R MARTIN +3

Method for monitoring the unauthorized use of a device

The invention is directed to systems and methods for detecting the loss, theft or unauthorized use of a device and / or altering the functionality of the device in response. In one embodiment, a device monitors its use, its local environment, and / or its operating context to determine that the device is no longer within the control of an authorized user. The device may receive communications or generate an internal signal altering its functionality, such as instructing the device to enter a restricted use mode, a surveillance mode, to provide instructions to return the device and / or to prevent unauthorized use or unauthorized access to data. Additional embodiments also address methods and systems for gathering forensic data regarding an unauthorized user to assist in locating the unauthorized user and / or the device.
Owner:BLANCCO TECH GRP IP OY

System for mitigating the unauthorized use of a device

The invention is directed to systems and methods for detecting the loss, theft or unauthorized use of a device and / or altering the functionality of the device in response. In one embodiment, a device monitors its use, its local environment, and / or its operating context to determine that the device is no longer within the control of an authorized user. The device may receive communications or generate an internal signal altering its functionality, such as instructing the device to enter a restricted use mode, a surveillance mode, to provide instructions to return the device and / or to prevent unauthorized use or unauthorized access to data. Additional embodiments also address methods and systems for gathering forensic data regarding an unauthorized user to assist in locating the unauthorized user and / or the device.
Owner:BLANCCO TECH GRP IP OY

Systems and methods for recovering low power devices

The invention is directed to systems and methods for detecting the loss, theft or unauthorized use of a device and / or altering the functionality of the device in response. In one embodiment, a device monitors its use, its local environment, and / or its operating context to determine that the device is no longer within the control of an authorized user. The device may receive communications or generate an internal signal altering its functionality, such as instructing the device to enter a restricted use mode, a surveillance mode, to provide instructions to return the device and / or to prevent unauthorized use or unauthorized access to data. Additional embodiments also address methods and systems for addressing devices that have low or no power.
Owner:BLANCCO TECH GRP IP OY

System for warming lower extremities of supine persons

A warming system, mounted to the foot of a bed, warms a person's lower extremities by directing air into the space between the mattress and overlaying blankets. A blower directs air into an elongated distribution chamber having many tiny exit apertures. The chamber is mounted at the foot of the bed, so that air exiting the apertures warms the person's feet. For maximum thermal transfer, the chamber is placed under the sheet and any blankets, but above the mattress cover and fitted sheet. The chamber may be implemented by a length of open cell foam, a hollow manifold with many punctures or other tiny distribution apertures, collapsible pocket, etc. While the person is lying on the bed beneath the blankets, with feet proximate the foot of the bed, the blower directs temperature-regulated air into the chamber and through the exit apertures, thereby warming the person's feet. A temperature regulator ensures a normothermic air temperature (or alternatively, hyperthermic air temperature.) Thus, the invention helps relieve or prevent “cold feet” by directing normothermic air at a person's lower extremities. Additionally, by applying heat to the feet and legs, the invention encourages blood flow by virtue of sympathetic vasodilation and local temperature-mediated vasodilation. The invention is also believed to prevent some leg and foot ulcers from forming by maintaining the lower extremity at a near normal temperature during sleep.
Owner:GEN ELECTRIC CAPITAL
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