A
system and method for monitoring and controlling the administration of at least one
drug having
anesthetic properties are provided. In certain embodiments, the method includes assembling physiological data, obtained from a plurality of sensors placed on a subject, into sets of time-
series data, separating, from the sets of time-
series data, a plurality of
low frequency signals, and determining, from the plurality of
low frequency signals, at least one of coherence information and synchrony information. The method can also include identifying, using the at least one of the coherence information and the synchrony information, spatiotemporal signatures indicative of at least one of a current state and a predicted future state of the patient consistent with the administration of at least one
drug having
anesthetic properties and generating a report indicating at least one of the current state and the predicted future state of the patient induced by the
drug.