109results about How to "Good technique" patented technology

A method of determining an ischemic event includes the steps of: monitoring and storing an initial electrocardiogram vector signal (x, y, z) of a known non-ischemic condition over the QRS, ST and T wave intervals; calculating and storing a J-point of the vector signal and a maximum magnitude of a signal level over the T wave interval; monitoring a subsequent electrocardiogram vector signal over the QRS, ST and T wave intervals; measuring and storing the magnitude (Mag.) of the vector difference between a subsequent vector signal and the initial vector signal; measuring and storing the angle (Ang.) difference between a subsequent vector and the initial vector at points; regressing a line from points about 25 milliseconds prior to the J point and about 60 milliseconds after the J-point and determining the slope of the regression line and the deviation of the angle difference of the regression line; regressing a line from points about 100 milliseconds prior to the maximum magnitude of the signal level over the T wave interval and determining the slope of the regressing line and the deviation of the angle difference of the regression line; and comparing the slope and deviation of the lines from the J point and the T wave interval to a set of known values to determine the presence of an ischemic event.

Disclosed embodiments include thermoelectric-based thermal management systems and methods configured to heat and / or cool an electrical device. Thermal management systems can include at least one electrical conductor in electrical and thermal communication with a temperature-sensitive region of the electrical device and at least one thermoelectric device in thermal communication with the at least one electrical conductor. Electric power can be directed to the thermoelectric device by the same electrical conductor or an external power supply, causing the thermoelectric device to provide controlled heating and / or cooling to the electrical device via the at least one electrical conductor. The thermoelectric management system can be integrated with the management system of the electrical device on a printed circuit substrate.

A method of diverting fluid flow from a first vessel including an occlusion to a second vessel includes deploying a prosthesis at least partially in a fistula and making valves in the second vessel incompetent. Making the valves in the second vessel incompetent includes at least one of using a reverse valvulotome to cut the valves, inflating a balloon, expanding a stent, and lining the second vessel with a stent.

A device includes a first end portion, a second end portion, an intermediate portion, and a graft material. The first end portion has a first end diameter. The second end portion has a second end diameter smaller than the first end diameter. The first end portion comprises a first material. The second end portion comprises a second material different than the first material. The intermediate portion is between the first end portion and the second end portion. The intermediate portion tapers between the first end portion and the second end portion. The graft material is coupled to at least the intermediate portion.

A method of diverting fluid flow from a first vessel including an occlusion to a second vessel includes deploying a prosthesis at least partially in a fistula and making valves in the second vessel incompetent. Making the valves in the second vessel incompetent includes at least one of using a reverse valvulotome to cut the valves, inflating a balloon, expanding a stent, and lining the second vessel with a stent.

A method for machining workpieces (6) uses a moving laser beam (4), whereby the laser tool (3) is held at a separation above the workpiece (6) by means of a multi-axis mechanical manipulator (2) with a manipulator hand (8) and moved along a given track in an offset movement. During the machining process an at least partly opposing compensation movement of the laser beam (4) is superimposed on the offset movement. A device is provided for machining workpieces (6) with a moving laser beam (4). The laser tool (3) is held by means of a multi-axis mechanical manipulator (2) and a device for generation of a opposing compensation movement of the laser beam (4) is superimposed on the offset movement.

One embodiment of the invention relates to a microfluidic apparatus for performing two dimensional biomolecular separations. According to one aspect of the invention, after a first dimension separation in a first microchannel, the sample material is electrokinetically and simultaneously transferred to an array of microchannels in the second dimension (e.g., by changing the electric potentials at the reservoirs connected to the microchannels). Preferably any separation accomplished in the first dimension is completely retained upon transfer to the second dimension. According to another aspect of the invention, the separation in the second dimension is performed using a temperature gradient (e.g., a spatial or temporal temperature gradient). According to one embodiment of the invention, the biomolecular material comprises DNA and the first dimension separation is a sized-based separation and the second dimension separation is a sequence-based separation.

The invention provides a medical device having a thermostat for temperature measurement, irrigation / aspiration ports for fluid exchange and application of therapeutic modalities, a pressure manometer for pressure measurement, and an external system for control of temperature, pressure, and flow rate. When applied to the eye, eyelid and orbit, this device can be used in hypothermia or hyperthermia applications, the control of intraocular pressure (IOP), and the application of treatment modalities. Methods of using the device in treating patients suffering from central retinal artery occlusion, anterior optic nerve disease, pathology of the choroid and retina including the macula, inflammation of the eye including the vitreous and anterior segment, glaucoma, inflammation and / or infections of the anterior and / or posterior segment of the eye, treatment before / during / after surgery of the eye, and the application of treatment modalities including iontophoresis through a semi-permeable membrane are described.

The present disclosure provides for methods, systems and apparatus for monochromatic UV light sterilization of container systems and / or container-packaged products. More particularly, the present disclosure provides for improved methods, systems and apparatus for monochromatic UV light sterilization of liquid and / or solid products / solutions and / or packaging / container systems for liquid and / or solid products / solutions (e.g., parenteral pharmaceutical products / solutions and / or packaging / container systems for parenteral pharmaceutical products / solutions). In exemplary embodiments, the present disclosure provides for improved systems and methods for the sterilization of container systems and / or container-packaged products using monochromatic, continuous wave, high-intensity, incoherent light in multiple light source configurations, wherein such sterilization regimen achieves a desired sterilization level without negatively affecting the physical properties of the package / container systems and / or the efficacy of the underlying products / systems.

Disclosed embodiments include thermoelectric-based thermal management systems and methods configured to heat and / or cool an electrical device. Thermal management systems can include at least one electrical conductor in electrical and thermal communication with a temperature-sensitive region of the electrical device and at least one thermoelectric device in thermal communication with the at least one electrical conductor. Electric power can be directed to the thermoelectric device by the same electrical conductor or an external power supply, causing the thermoelectric device to provide controlled heating and / or cooling to the electrical device via the at least one electrical conductor.

A catheter system can include a tubular body, and at least one of a targeting system coupled to the tubular body, an expandable member, or a fluid injection port. A method of identifying a bifurcation can include inserting a catheter system into a first vessel, positioning the catheter system at a first location, expanding an expandable member to occlude the first vessel, delivering contrast material so the contrast material pooling proximate to the expandable member, and reviewing a shape of the contrast material in the first vessel under fluoroscopy.

To control cardiac arrhythmias such as atrial fibrillation post-operatively, various non-ablative agents include polymers, fibroblasts, neurotoxins, and growth factors are introduced into one or more cardiac fat pads into the atrioventricular nodal fat pad in proximity to the autonomic ganglia therein. Any desired technique may be used for introducing the agent, including injection. The sinoatrial nodal fat pad target site and the atrioventricular nodal fat pad target site are identified using a stimulator, which may have electrodes coupled thereto or which may coupled to electrodes built into a delivery system.