13998results about "Therapeutic heating" patented technology

An electrosurgical system comprises a generator and an instrument including a first electrode, a second electrode, and an insulating spacer separating the first and second electrodes. The generator repeatedly measures a characteristic of the radio frequency output such as the impedance between the first and second electrodes. The generator analyses the impedance measurements, and interrupts the radio frequency signal when the rate of change of the impedance is such as to indicate the onset of a “flare-out”. In this way, the power is reduced before the flare-out leads to permanent damage or failure of the instrument.

Devices and methods for determining analyte levels are described. The devices and methods allow for the implantation of analyte-monitoring devices, such as glucose monitoring devices that result in the delivery of a dependable flow of blood to deliver sample to the implanted device. The devices include unique architectural arrangement in the sensor region that allows accurate data to be obtained over long periods of time.

A method and apparatus for carrying our thermal ablation of target tissue is disclosed. The apparatus includes an RF ablation device having a multi-electrode electrode assembly designed to be deployed in target tissue, defining a selected-volume tissue region to be ablated, and having infusion channels for infusing a liquid into the target tissue during the ablation process. A control unit in the apparatus is operably connected to an RF energy source, for controlling the RF power level supplied to the electrodes, and to an infusion device, for controlling the rate of infusion of a liquid through the device into the tissue. During both electrode deployment and tissue ablation, impedance and or temperature measurements made within the tissue are used to control the RF source and infusion device, for optimizing the time and extent of tissue ablation.

A method and apparatus for calculating current lost through a patient during a treatment of a patient using an electromagnetic energy delivery system is disclosed. The system generates electromagnetic energy, contacts a skin surface of the patient, transfers the electromagnetic energy to tissue beneath the surface of the skin, detects a value of at least one characteristic of the electromagnetic energy utilizing synchronous undersampling, and calculates the current lost through the patient. The characteristic measured may be a value of current of the electromagnet energy. An adjustable matching network may be utilized to maximize power to the tissue of the patient. Values of the impedance of the matching network may be utilized to determine the electromagnetic energy delivered to the tissue of the patient. A current correction factor is determined from the impedance of the matching network and utilized to calculate the current lost through the patient.

An apparatus for transmural ablation using an instrument containing two electrodes. The electrodes extend along the surfaces of mating jaw members which are moveable between open and clamped positions. The electrodes are connected to an RF energy source so that, when activated, they are of opposite polarity. An EKG sensor is located on one of the jaw members and spaced from the electrode so that, when the electrodes are activated to form a line of ablation, the EKG sensor contacts the tissue outside the line of ablation. A pacing electrode is located on one of the jaw members so as to be on the opposite side of the line of ablation from the EKG sensor. Thus, if the line of ablation is not transmural, the EKG sensor will be able to detect signals generated by the pacing electrode.

Various embodiments provide compositions that exhibit positive temperature coefficient of resistance (PTCR) properties for use in thermal interactions with tissue—including thermal sensing and I2R current-limiting interactions. Embodiments also provide tissue-engaging surfaces having PTCR materials that provide very fast switching times between low resistance and high, current-limiting resistance. One embodiment provides a matrix for an electrosurgical energy delivery surface comprising a PTCR material and a heat exchange material disposed within an interior of the matrix. The PTCR material has a substantially conductive state and a substantially non-conductive state. The heat exchange material has a structure configured to have an omni-directional thermal diffusivity for exchanging heat with the PTCR material to cause rapid switching of the PTCR material between the conductive state and non-conductive state. Preferably, the structure comprises a graphite foam having an open cell configuration. The matrix can be carried by tissue contacting surfaces of various electrosurgical devices.

The present invention provides an apparatus and a method for producing a virtual electrode within or upon a tissue to be treated with radio frequency alternating electric current, such tissues including but not limited to brain, liver, cardiac, prostate, breast, and vascular tissues and neoplasms. An apparatus in accordance with the present invention includes a source of super-cooled fluid for selectively providing super-cooled fluid to the target tissue to cause a temporary cessation of cellular or electrical activity, a supply of conductive or electrolytic fluid to be provided to the target tissue, and alternating current generator, and a processor for creating, maintaining, and controlling the ablation process by the interstitial or surficial delivery of the fluid to a tissue and the delivery of electric power to the tissue via the virtual electrode. A method in accord with the present invention includes delivering super-cooled fluid to the target tissue to cause a temporary cessation of cellular or electrical activity, evaluating whether the temporary cessation of cellular or electrical activity is the desired cessation of cellular or electrical activity, and if so, delivering a conductive fluid to the predetermined tissue ablation site for a predetermined time period, applying a predetermined power level of radio frequency current to the tissue, monitoring at least one of several parameters, and adjusting either the applied power and / or the fluid flow in response to the measured parameters.

A collapsible electrode catheter assembly (10) having a delivery system (12) for controlling a catheter guide tube (16) having a catheter distal end assembly (22) thereon. The catheter distal end assembly (22) has an electrode structure (28) on an expanding assembly (34) for enlarging the electrode structure (28) in an expanded condition. A balloon structure (48) is used to expand and contract the expanding assembly (34) when an inflation medium (64) is alternately introduced into and withdrawn from the balloon structure (48).

A system for ablating tissue includes a reusable control unit including a processor monitoring and controlling ablation and a control interface receiving input to and output from the processor in combination with a disposable procedure set releasably connectable to the control unit to couple to the control interface for communication with the processor.

According to some embodiments, a microdermabrasion device for treating skin comprises a handpiece assembly having a distal end and a proximal end. The handpiece assembly includes at least one delivery conduit and at least one waste conduit. The microdermabrasion device additionally comprises a tip configured to be positioned along the distal end of the handpiece assembly, wherein the tip is adapted to contact skin surface. In several embodiments, the tip comprises a lip, a first opening in fluid communication with the fluid delivery conduit and a second opening in fluid communication with the waste conduit. In one embodiment, the device includes one or more abrasive elements positioned along a distal end of the tip, wherein the abrasive elements are configured to selectively remove skin as the tip is moved relative to a skin surface. In some embodiments, the delivery conduit is configured to selectively deliver at least one time-release material to the skin surface being treated.

This invention relates to the destruction of pathological volumes or target structures such as cancerous tumors or aberrant functional target tissue volumes by direct thermal destruction. In the case of a tumor, the destruction is implemented in one embodiment of the invention by percutaneous insertion of one or more radiofrequency probes into the tumor and raising the temperature of the tumor volume by connection of these probes to a radiofrequency generator outside of the body so that the isotherm of tissue destruction enshrouds the tumor. The ablation isotherm may be predetermined and graded by proper choice of electrode geometry and radiofrequency (rf) power applied to the electrode with or without temperature monitoring of the ablation process. Preplanning of the rf electrode insertion can be done by imaging of the tumor by various imaging modalities and selecting the appropriate electrode tip size and temperature to satisfactorily destroy the tumor volume. Computation of the correct three-dimensional position of the electrode may be done as part of the method, and the planning and control of the process may be done using graphic displays of the imaging data and the rf ablation parameters. Specific electrode geometries with adjustable tip lengths are included in the invention to optimize the electrodes to the predetermined image tumor size.

An instrument and method are provided for sealing and joining or hemostatically dividing tissue, which is particularly suitable for laparoscopic and endoscopic surgery. The instrument makes use of the controlled application of a combination of heat and pressure to seal adjacent tissues, to join adjacent tissues, or to anastomose tissues, whereby tissue is heated for an optimal time and at an optimal temperature under optimal pressure to maximize tissue seal strength while minimizing collateral tissue damage. The instrument of the present invention is lightweight and therefore portable, and is particularly useful in field conditions where a source of external power may not be readily available.

The present invention relates to a method and a device for transporting a molecule through a mammalian barrier membrane of at least one layer of cells comprising the steps of: ablating the membrane with an electric current from a treatment electrode; and utilizing a driving force to move the molecule through the perforated membrane.

The present invention provides an apparatus and a method for producing a virtual electrode within or upon a tissue to be treated with radio frequency alternating electric current, such tissues including but not limited to liver, lung, cardiac, prostate, breast, and vascular tissues and neoplasms. An apparatus in accord with the present invention includes a supply of a conductive or electrolytic fluid to be provided to the patient, an alternating current generator, and a processor for creating, maintaining, and controlling the ablation process by the interstitial or surficial delivery of the fluid to a tissue and the delivery of electric power to the tissue via the virtual electrode. A method in accord with the present invention includes delivering a conductive fluid to a predetermined tissue ablation site for a predetermined time period, applying a predetermined power level of radio frequency current to the tissue, monitoring at least one of several parameters, and adjusting either the applied power and / or the fluid flow in response to the measured parameters.

A wound therapy and tissue management system utilizes fluid differentiation. Fluid is differentiated by establishing a gradient within the system. A gradient can be established with matter or energy. Patient interfaces for establishing, maintaining and varying one or more gradients include transfer elements with first and second zones having different flow coefficients. The transfer elements exchange fluid with a patient, generally through a wound site, and with external components of the system. Osmotic solution gradients are controlled by a methodology involving the present invention for extracting solutions, which can include toxins, from patients and for introducing fluids and sumping air to wound sites.

An endoscopic forceps for treating tissue includes a handle assembly having a elongated shaft extending therefrom which is movable relative to the handle assembly by an actuator. The forceps also including an end effector assembly attached to a distal end of the shaft which has first and second jaw members which are movable about a pivot from a first position in spaced relation relative to one another to a second position for clamping tissue. Each of the jaw members include: an insulative outer housing having an electrically conductive, inwardly facing tissue contacting surface and a proximal flange with a camming surface. The proximal flange being provided with a spring-like tail which mounts within the distal end of the elongated shaft to bias the jaw members in an open configuration. The actuator is movable relative to the handle to actuate the elongated shaft to cam the proximal flanges to pivot the jaw members toward the second position to clamp tissue.

Apparatus and methods for treating an intervertebral disc by ablation of disc tissue. A method of the invention includes positioning at least one active electrode within the intervertebral disc, and applying at least a first high frequency voltage between the active electrode(s) and one or more return electrode(s), wherein the volume of the nucleus pulposus is decreased, pressure exerted by the nucleus pulposus on the annulus fibrosus is reduced, and discogenic pain of a patient is alleviated. In other embodiments, a curved or steerable probe is guided to a specific target site within a disc to be treated, and the disc tissue at the target site is ablated by application of at least a first high frequency voltage between the active electrode(s) and one or more return electrode(s). A method of making an electrosurgical probe is also disclosed.

Ergonomic systems which provide medical therapy, comfort and enhanced function are provided. Surfaces are provided with adjustable contour, transient force damping and temperature. The technologies are applied to footwear, seating surfaces an cryotherapy devices. The cooling and cryotherapy system employ an evaporator in close proximity to skin, and therefore employ methods to reduce risk of frostbite. Advanced control and power supply options are disclosed.

A catheter is adapted to exchange heat with a body fluid, such as blood, flowing in a body conduit, such as a blood vessel. The catheter includes a shaft with a heat exchange region disposed at its distal end. This region may include hollow fibers which are adapted to receive a remotely cooled heat exchange fluid preferably flowing in a direction counter to that of the body fluid. The hollow fibers enhance the surface area of contact, as well as the mixing of both the heat exchange fluid and the body fluid. The catheter can be positioned to produce hypothermia in a selective area of the body or alternatively positioned to systemically cool the entire body system.

An ablation apparatus system for treating tissues in a patient, the ablation apparatus comprising temperature sensing means for measuring a temperature, wherein said temperature sensing means comprises a temperature sensing probe and at least one temperature sensing wire secured to the temperature sensing probe; force measuring means for measuring force exerted onto the temperature sensing probe by a tissue; and RF current generating means for generating RF current, wherein the RF current generating means is connected to and controlled by the temperature sensing means and force measuring means, adapted for supplying RF current to the temperature sensing probe as an electrode for tissue treatment.

An apparatus for cooling a skin surface includes an RF device that has an RF electrode with dielectric and conductive portions. The RF device is configured to be coupled to an RF energy source. A cooling member is coupled to the RF device. A memory is coupled to the RF device. The memory is configured to store information to facilitate operation of at least one of the RF electrode, the cooling member, and the RF energy source.

An instrument and method are provided for sealing and joining or hemostatically dividing tissue, which is particularly suitable for laparoscopic and endoscopic surgery. The instrument makes use of the controlled application of a combination of heat and pressure to seal adjacent tissues, to join adjacent tissues, or to anastomose tissues, whereby tissue is heated for an optimal time and at an optimal temperature under optimal pressure to maximize tissue seal strength while minimizing collateral tissue damage. The instrument of the present invention is lightweight and therefore portable, and is particularly useful in field conditions where a source of external power may not be readily available.

A catheter is adapted to exchange heat with a body fluid, such as blood, flowing in a body conduit, such as a blood vessel. The catheter includes a shaft with a heat exchange region disposed at its distal end. This region may include at least one balloon which is adapted to receive a remotely cooled heat exchange fluid preferably flowing in a direction counter to that of the body fluid. Embodiments including multiple balloons enhance the surface area of contact, and the mixing of both the heat exchange and the body fluid. The catheter can be positioned to produce hypothermia in a selective area of the body without cooling the entire body system. It is of particular advantage in brain surgeries where stroke, trauma or cryogenic tumors can best be addressed under hypothermic conditions.

A convective warmer to which blankets of different dimensions may be connected is capable of providing air to the various blankets at flow rates that optimally inflate those blankets to achieve the optimal clinical result for the patients covered by those blankets. The blanket connected to the warmer may range from a full size adult warming blanket to a pediatric warming blanket. The convection warmer may have multiple fixed air flow rates each selectable by a user, via switch(es) either electronically or mechanically. For the electronic selection of a given flow rate, a motor adaptable to rotate a different speeds is used. To vary the flow rate mechanically, a valve is controlled to vary the amount of air that may pass to the blanket. Instead of different fixed flow rates, variable air flow rates, selectable by the user, may be used. Also, a feedback circuit that maintains the pressure sensed at the outlet of the warmer to a preset pressure may be used to eliminate the need for user intervention.

The present invention provides a system for achieving erythema and / or mild edema in an upper layer of skin, without causing blisters, and without the risk of high fluence levels or critical need for cooling.

A method and apparatus for calculating current lost through a patient during a treatment of a patient using an electromagnetic energy delivery system is disclosed. The system generates electromagnetic energy, contacts a skin surface of the patient, transfers the electromagnetic energy to tissue beneath the surface of the skin, detects a value of at least one characteristic of the electromagnetic energy utilizing synchronous undersampling, and calculates the current lost through the patient. The characteristic measured may be a value of current of the electromagnet energy. An adjustable matching network may be utilized to maximize power to the tissue of the patient. Values of the impedance of the matching network may be utilized to determine the electromagnetic energy delivered to the tissue of the patient. A current correction factor is determined from the impedance of the matching network and utilized to calculate the current lost through the patient.

This relates to methods and devices for treating reversible chronic obstructive pulmonary disease, and more particularly, relates to a device for exchanging energy with airway tissue such as that found in the airway of human lungs. The exchange of energy with this airway tissue in the airways reduces the ability of the air ways to constrict and / or reduces the resistance within the airway to the flow of air through the airway. This also relates to a method for decreasing responsiveness or decreasing resistance to airflow of airways involves the transfer of energy to or from the airway walls to prevent or reduce airway constriction and other symptoms of lung diseases. The treatment reduces the ability of the airway to contract during an acute narrowing of the airways, reduces mucus plugging of the airways, and / or increases the airway diameter. The methods according to the present invention provide a longer duration and / or more effective treatment for lung diseases than currently used drug treatments, and obviate patient compliance issues. This also includes additional steps that reduce the ability of the lung to produce at least one of the symptoms of reversible obstructive pulmonary disease and to reduce the resistance to the flow of air through a lung.

A medical probe assembly, system, and methods for the use thereof to treat tissue are described. The system optionally comprises an energy source, two internally-cooled probe assemblies, and one or more cooling devices to provide cooling to at least one of the probe assemblies. The probe assemblies may be configured in a bipolar mode, whereby current flows preferentially between the probe assemblies. The probe assemblies and system described herein are particularly useful to deliver radio frequency energy to a patient's body. RF energy delivery may be used for various applications, including the treatment of pain, tumor ablation and cardiac ablation.