Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Anti-inflammation medicine and method for preparing same

A technology of drug and anti-inflammatory effect, which is applied in the field of anti-inflammatory drugs and their preparation, and can solve problems such as slow efficacy

Active Publication Date: 2006-12-27
JUMPCAN PHARMA GRP
View PDF0 Cites 9 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In clinical use, although the curative effect is definite, but the curative effect is slow, and the efficacy needs to be further improved

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] 1A) Dandelion 40 grams, Banlangen 15 grams, Scutellaria baicalensis 15 grams, Kudiding 10 grams. Among them, the dandelion, isatis root, and Kudiding sammaid are decocted twice with water, each time for 1 hour, the extract is concentrated to an appropriate amount, and ethanol is added to make the alcohol content 70%, and it is filtered after standing, and the filtrate is recovered with ethanol and concentrated to obtain Water extraction and alcohol sedimentation; take another Scutellaria baicalensis, put it into boiling water and decoct twice, each time for 1 hour, combine the extracts, concentrate to an appropriate amount, add ethanol to make the alcohol content reach 50%, filter after standing, and recover the ethanol from the filtrate, The solution was kept warm at 80°C, adjusted to pH 1.5 with hydrochloric acid, allowed to stand and then filtered to obtain baicalin. Add baicalin to the previously prepared water-extracted alcohol precipitate to obtain the extract of ...

Embodiment 2

[0030] Embodiment 2: preparation oral liquid

[0031] Take 500 grams of dandelion, 188 grams of isatidis, and 125 grams of kudiding, add water and decoct twice, each time for 1 hour. Combine the extracts, concentrate to a clear paste with a relative density of 1.13-1.15 (60-70°C), add ethanol to make the alcohol content 75%, leave it for 48 hours, filter, recover the ethanol from the filtrate, add water to 500 ml, and leave it for 48 hours hour, filtered, and the filtrate was adjusted to pH 6.5 with 10% sodium hydroxide solution, and set aside.

[0032] Take another 188 grams of Scutellaria baicalensis, put it into boiling water and decoct twice, first decoct for 10 minutes each time, adjust the pH value to 6.5 with 10% sodium hydroxide solution, decoct for 1 hour, combine the extracts, concentrate to a relative density of 1.08 ~1.11 (60~70℃), adjust the pH value to 6.5, add ethanol to make the alcohol content reach 50%, let it stand for 24 hours, filter, after recovering the...

Embodiment 3

[0035] Example 3: Pharmacological Experimental Study on Anti-Inflammation in Mice

[0036] 1. Experimental materials

[0037] Animals: 18-22 grams of Kunming mice, half male and half male.

[0038] Medicine: the oral liquid that embodiment 2 makes.

[0039] 2. Method

[0040] 36 healthy mice were randomly divided into 3 groups: a blank control group, a large dose of the oral liquid group of the present invention (42g / kg body weight) and a small dose of the oral liquid group of the present invention (14g / kg body weight). 12 in each group, half male and half male.

[0041] The administration was administered once 6 hours and 1 hour before the acute inflammation was caused, and each time the mice in the blank control group and the administration group were given 0.21ml / 10g body weight normal saline and the corresponding experimental liquid respectively. The dosage for each administration of the large-dose oral liquid group of the present invention is 21 g / kg body weight, and th...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to a Chinese medicinal extract having anti-inflammation action, its medicinal preparation and use thereof, wherein the preparation comprises dandelion, isatic root, Herba Corydalis bungeanae, baikal skullcap root or scutellaria root glycosides.

Description

technical field [0001] The invention relates to a traditional Chinese medicine extract with anti-inflammatory effect and its pharmaceutical preparation and application, in particular to a traditional Chinese medicinal oral liquid preparation with anti-inflammatory effect. The medicine of the invention has heat-clearing and toxic substances removing or anti-inflammation or detumescence effect, and is used for treating diseases such as mumps, pharyngitis, tonsillitis or furunculosis. It belongs to the field of medicine. Background technique [0002] The anti-inflammatory tablet composed of dandelion, isatis root, kudiding and scutellaria baicalensis is suitable for heat, evil, fire and poison. It has been clinically used for a long time to treat mumps, pharyngitis, tonsillitis or boils and other diseases. Dandelion is bitter and cold, has the functions of clearing heat and detoxification, reducing swelling and dispelling stagnation, and is used as a monarch drug in prescripti...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K36/66A61P11/04A61P17/02A61K31/7048
Inventor 曹龙祥李昌龙田刚
Owner JUMPCAN PHARMA GRP
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com