101 results about "Narcotic" patented technology

Disclosed here are effervescent granules having a controllable rate of effervescence. In some embodiments, the such granules comprise an acidic agent, an alkaline agent, a pharmacologically active agent, hot-melt extrudable binder capable of forming a eutectic mixture with the acidic agent and, optionally, a plasticizer. The effervescent granules are made by a hot-melt extrusion process. The present invention also provides a thermal heat process for preparing a pharmacologically active agent containing effervescent granule. In certain aspects, the granules contain pharmacologically active agents such as narcotics, antidiarrheal agents, antiviral agents, anxiolytic agents, a cholesterol lowering agent, an alpha adrenergic blocking agent, a phenanthrene derivative. By way of example, some of the narcotics that may be included in the granules and in the process of preparing the granules include, by way of example: phenanthrene derivatives (e.g., morphine sulfate), and morphine derivatives (e.g., hydromorphone hydrochloride).

Disclosed here are effervescent granules having a controllable rate of effervescence. In some embodiments, the such granules comprise an acidic agent, an alkaline agent, a pharmacologically active agent, hot-melt extrudable binder capable of forming a eutectic mixture with the acidic agent and, optionally, a plasticizer. The effervescent granules are made by a hot-melt extrusion process. The present invention also provides a thermal heat process for preparing a pharmacologically active agent containing effervescent granule. In certain aspects, the granules contain pharmacologically active agents such as narcotics, antidiarrheal agents, antiviral agents, anxiolytic agents, a cholesterol lowering agent, an alpha adrenergic blocking agent, a phenanthrene derivative. By way of example, some of the narcotics that may be included in the granules and in the process of preparing the granules include, by way of example: phenanthrene derivatives (e.g., morphine sulfate), and morphine derivatives (e.g., hydromorphone hydrochloride).

A computerized medication dispensing station that addresses anesthesia medication management and tracking problems is disclosed. Medications, including narcotic and non-narcotic, and supplies for use in anesthesia, are stored in secured, semi-secured, and unsecured containers of a mobile station. A computer housed in the station is used to track the anesthesiology items that have been removed from the station. For each item removed, the time of removal, who removed it, and to whom it was administered is tracked. Items that are not administered to a patient are returned to the pharmacy or wasted (i.e., disposed in accordance with regulations). Each type of event (administration to a patient, return, or waste) is documented so that a health care institution can track usage of items, including narcotic medications, for use in anesthesia.

A compact scanning apparatus has an infrared laser adapted to emit light. The light is delivered as a beam by an optical system to illuminate an interrogation area on the surface of an object being scanned. Such illumination has sufficient intensity and duration to cause selective desorption of molecules of the contraband substance, which are present on the surface, without substantially damaging the surface. A collection system collects at least a portion of the desorbed molecules. At least a portion of the collected molecules is thermally decomposed to form NO2 and transferred to a reaction cell containing an aqueous, alkaline, luminol-containing solution. The NO2 reacts with the luminol to produce light by chemiluminescence. A light detector registers the presence of this light as indicative of the detection of the contraband substance, and activates a signaling device to provide an audible or visible alarm. The apparatus rapidly detects the presence of a wide variety of contraband substances in an accurate, reliable manner. It provides for automated screening, with the result that vagaries of human performance are virtually eliminated. False alarms are reduced and detection efficacy is increased. A traceable residue of the detected contraband is left on the article for use in forensic analysis.

A multi-zonal system and method for detecting contraband substances associated with a human subject. Objects containing such substances may be carried by the subject or in a garment worn by the subject, or as vapors entrained by the subject's garments. Alternatively, the substance may be present as small particles or residues present on skin, garment fibers, or the like that may be dislodged from the subject or his immediate effects. The system comprises: (i) an examination station through which the subject passes; (ii) sample generation means to produce a sample for analysis, comprising a plurality of air jets disposed in the examination station to impinge flowing gas onto pre-selected zones on the subject; (iii) collection means operative to acquire and convey the sample, comprising a plurality of collection ports disposed in the examination station to receive gas deflected by the subject from the air jets; (iv) analysis means in communication with the collection means to receive the sample and carry out a chemical analysis to detect the contraband substances; and (v) signal means operably connected to the analysis means for indicating detection of the contraband substances. Preferably the system employs a chemiluminescent detector based on the reaction of luminol with NO2 produced by pyrolysis of explosive or other contraband substance and is capable of high throughput, accurate screening in real time of a large number of subjects, e.g. persons being screened in an airport.

A compact scanning apparatus has an infrared laser adapted to emit light. The light is delivered as a beam by an optical system to illuminate an interrogation area on the surface of an object being scanned to cause selective desorption of molecules of the contraband substance, which are present on the surface, without substantially damaging the surface. A collection system collects at least a portion of the desorbed molecules. At least a portion of the collected molecules is thermally decomposed to form NO2 and transferred to a reaction cell containing an aqueous, alkaline, luminol-containing solution. The NO2 reacts with the luminol to produce light by chemiluminescence. A light detector registers the presence of this light to carry out a rapid screening of the object for the possible presence of the contraband substance. The apparatus further includes a supplemental detector such as a GC / IMS detector that is activated in response to the detection of the chemiluminescent light. The supplemental detector provides confirmation of the detection of contraband substance and activates a signaling device to provide an audible or visible alarm. The rapid pre-screening permits the apparatus to identify suspicious items, while the supplemental detection system can be optimized for more intense, but time-consuming scrutiny of just the suspicious items. Both effective detection and high throughput are thereby achieved in an accurate, reliable manner.

The present disclosure involves a system for monitoring patients, and more specifically post-operative patients receiving narcotics, and a novel apparatus for automatically delivering a narcotic-reversing agent, including but not limited to the agent commonly known as naloxone, in response to dangerous respiratory conditions such as respiratory depression or other undesired consequences caused by reaction to narcotic dosage.

An apparatus is provided for detecting whether a person has handled explosives, narcotics or other substances of interest. The apparatus includes a metallic sample collection surface on which a person may place a finger. Upon removal of the finger, the metallic sample collection surface is moved to a desorber. The desorber heats the metallic surface sufficiently to vaporize residue transferred from the person. The vaporized residue then is transmitted to a detector for analysis. The detector also may include a fingerprint reading apparatus for reading the fingerprint of the person and comparing the fingerprint to known fingerprint data.

The present invention provides an ion pair compound of the formula [narcotic]+[A]−, wherein [narcotic]+ represents at least one cation of at least one narcotic agent or one or more stereochemical isomers thereof and [A]− represents at least one anion of at least one NSAID or one or more stereochemical isomers thereof. An example of the ion pair compound is propoxyphene diclofenate. The ion pair compounds, or their pharmaceutical compositions, are useful in methods of treating a wide variety of conditions that indicate analgesics, anti-inflammatory agents, or both. Under the conditions prescribed for their use, the ion pair compounds exhibit poor or complete insolubility but excellent chemical stability in low pH environments, such as those found in the stomach. The ion pair compounds readily dissolve and dissociate in higher pH environments such as the small intestine to release the constituent narcotic and NSAID.

The invention discloses a Chinese medicinal narcotic. The Chinese medicinal narcotic comprises the following Chinese medicinal components in part by weight: 8 to 10 parts of hindu datura flower, 8 to 10 parts of mint, 2 to 3 parts of toad venom, 2 to 3 parts of pepper, 2 to 3 parts of borneol, 8 to 10 parts of manchurian wildginger, 8 to 10 parts of unprocessed kusnezoff monkshood root, 8 to 10 parts of szechuan lovage rhizome, 8 to 10 parts of angelica sinensis, 8 to 10 parts of fried arisaema root, 8 to 10 parts of heartleaf houttuynia herb and 8 to 10 parts of poppy shell. The components of the narcotic are common pure traditional Chinese medicines, and the narcotic has rational compatibility, small toxic or side effect, anti-shock effect and high safety.

The invention discloses a method for monitoring traced propofol narcotic rapidly and sensitively. In the method, an ion mobility spectrometry technology is taken as a basic detection technology, and an anion mode is adopted to establish a method for monitoring traced propofol narcotic. The method comprises the following steps: feeding a gas sample containing propofol into an ion mobility spectrometry tester for analysis to obtain a detecting signal, and then carrying out qualitation and quantitation. According to the invention, the measurement of a narcotic sample can be detected in real time, and the limit of detection of the propofol narcotic can reach 0.5ppb. The detecting method is simple, convenient, rapid and efficient and is good in reliability.

The invention provides a medicament set control method applied to hospitals, and in particular relates to a medicament set control method, applied to operating rooms, of a medicament access system of common medicaments, narcotics and consumable materials. By the medicament set control method, the dispensing time of doctors is saved; dispensing errors are reduced; and information such as the types, quantity and the like of the used medicaments is recorded, so that the doctors can inquire conveniently and the medicaments are supplemented in time by prompt when the medicament storage quantity is insufficient.

The invention provides a group of novel medicinal compositions for treating infectious diseases of the urogenital system such as urinary tract infection and prostatitis, wherein the composition comprises the pharmaceutical effective combinations of the following materials: I) anti-infectious medicaments and second compounds of the precursors and pharmaceutically acceptable salts of the anti-infectious medicaments; II) medicaments for treating urethra stimulative symptoms, such as muscarinic receptor antagonist, alpha-adrenergic receptor antagonist and 5-alpha-reductase inhibitor or phosphodiesterase (PDE) antagonist and second compounds of the precursors and pharmaceutically acceptable salts of the medicaments; and III) analgesic medicaments or dopes and second compounds of the precursorsand pharmaceutically acceptable salts of the analgesic medicaments or dopes. The three classes of medicaments can be combined two by two (such as I+II, II+III or I+III) or combined together (such as I+II+III). The invention also provides group of novel methods for treating infectious diseases of the urogenital system such as urinary tract infection and prostatitis, which comprises a step of usinga therapeutically effective dose of the compositions of the invention.

The invention belongs to the technical field of lockers and relates to an external-damage-proof face recognition type locker. The external-damage-proof face recognition type locker comprises a cabinet body; the cabinet body is separated into a control box cell and a plurality of storage box cells; conductive circuit layers are arranged on outer surfaces of the cabinet body, storage box cell cabinet doors and a control box cell cabinet door; electric door locks are mounted at inner sides of the storage box cell cabinet doors; the control box cell is internally equipped with a main controller, a power supply, a sound alarm, a memory and a wireless transmission device; the control box cell cabinet door is provided with a sound making hole; the control box cell cabinet door is equipped with a mechanical lock, a face recognition device and a display screen; the storage box cells are internally provided with dangerous chemical detectors and narcotics detectors; the power supply is connected with the main controller; the main controller is connected with the sound alarm, the conductive circuit layers, the electric door locks, the dangerous chemical detectors, the narcotics detectors, the face recognition device and the display screen. By adopting the external-damage-proof face recognition type locker, objects are convenient to store and take, external damages can be prevented, the structure is firm, and dangerous goods and narcotics can be found in time.

The invention provides an anesthesia auxiliary support for anesthesia, the dilution problem of narcotic drugs is solved, meanwhile, static suction composite anesthesia can be conducted on a patient, anesthesia maintenance in the anesthesia process can be automatically switched, meanwhile, auxiliary awakening drugs can be injected after an operation is completed, and the anesthesia auxiliary support for anesthesia comprises a lifting table and an atomizer and is characterized by further comprising an automatic medicine feeding device fixedly connected to the upper end face of the lifting table,a stirring device located on the upper end face of the lifting table and located below the automatic medicine feeding device, and a switching device located below the lifting table and connected withthe stirring device. Anesthetic liquid can be diluted at same time, and then injected metering is more accurate; meanwhile, sequential control can be carried out to complete static suction combined anesthesia in an operation, and meanwhile, awakening drugs can be automatically injected into a patient after anesthesia is completed.

The invention discloses an anesthetic device with good anesthesia efficacy, wherein the anesthetic device comprises a box body; a motor box is fixedly connected at the bottom of an inner cavity of thebox body, a motor is fixedly connected at the right side of an inner cavity of the motor box, and a first gear is fixedly connected at the output end of the motor; a mixing box is arranged in the inner cavity of the box body and located at the top of the motor box; the bottom of the inner cavity of the motor box is movably connected with a stirring rod through a bearing, and the top of the stirring rod runs through the motor box and the mixing box and extends to the inner cavity of the mixing box. By arrangement of the motor, the first gear, the mixing box, the stirring rod, a second gear, stirring blades, a sealing sleeve and a T-branch tube, the effects of stirring mixing of anesthetics and prevention of uneven mixing of normal saline and anesthetics are achieved, so the problems that aconventional anesthesia device cannot adjust the concentration of anesthetics according to different needs of patients, is not ideal in effect of anesthesia, and brings inconvenience for patients andmedical staff.

The present invention relates to methods of alleviating pain with the administration of norketamine with a narcotic. More particularly, the invention provides a method of alleviating pain through the administration of a dose of norketamine, which, if administered alone would provide sub-optimal analgesic relief, yet provides analgesic relief when combined with a narcotic. In some embodiments, the combination of norketamine with a narcotic, further allows for the administration of a dose narcotic, which would be sub-optimal if used alone, but provides adequate pain relief in combination with norketamine. The invention relates to self-management of pain on an outpatient basis comprising administering via conventional routes, including transdermal, nasal, rectal, oral, transmucosal, intravenous, intramuscular, and other routes, one or more doses of norketamine / opioid compositions effective to alleviate pain to a subject suffering from pain. Uses of norketamine / opioid compositions would also apply, to treating headaches, drug abuse, mood and anxiety disorders, as well as other, neuropsychiatric disorders, both motoric and cognitive, such as Alzheimer's disease, Parkinson's syndrome, which are thought to be caused by neurodegeneration.

An explosive and narcotics detection system detects the presence of trace particles of those materials that are adhering to surfaces. The particles are removed from the surface, transported and collected in a particle collection medium, and then provided to detection instrument. Narcotics and explosive particles are often bound tenaciously to the surface, and simple techniques, such as blowing air, will either remove only the largest particles or none at all. Techniques for the removal of narcotics and explosives particles are described which utilize an aerosol mixture of aerosol particles in a gas stream to impact and more efficiently remove the target narcotics and explosives particles from the surface.

The invention discloses an amide compound, a preparation method and application thereof, and particularly provides a compound as shown in a formula (I), or a salt thereof, or an isotope replacement form thereof, or an optical isomer thereof, or a solvate thereof, or a crystal form thereof, or a prodrug thereof. According to the invention, the local anesthetic effect duration of the compound provided by the invention is obviously longer than that of a contrast drug bupivacaine; and compared with bupivacaine, the compound provided by the invention is higher in titer and better in safety, can bedecomposed and removed from plasma more quickly, and has a very good application prospect in preparation of local anesthetic drugs or local analgesic drugs.

The present disclosure involves a system for monitoring patients, and more specifically post-operative patients receiving narcotics / sedatives / opioids, and a novel apparatus for automatically delivering one or more substances such as a reversing agent, including but not limited to the agent commonly known as naloxone, in response to dangerous respiratory conditions such as respiratory depression or other undesired consequences caused by reaction to another dosage being delivered to the subject.

The invention belongs to the technical field of medicine and particularly relates to a double-effect anesthetic and a preparation method and application thereof.The invention discloses a compound shown in the general formula (I).The compound can generate analgesic flurbiprofen and anesthetic propofol after hydrolysis, the analgesic and the tranquilizer are combined, dosage frequency of anesthetists is reduced, the anesthetic process is quicker, the occurrence rate and the severity of propofol injection pain can be remarkably reduced, adverse reactions of single drug are reduced, and the anesthetic has the advantages that the anesthetic takes effects quick, lasting time is short, anesthetic efficiency is high, controllability in operation is high, and patients recover quickly.Please see the structural formula in the description, wherein R refers to O or a radical group in the description, and n is 2-4.

A system and a method for medication identification and inventory control is disclosed. The disclosed system and method were designed to track specified medications' (e.g., narcotics and controlled substances) inventory from manufacturer's lot number all the way to the use / waste stage of the medications and to provide periodic reports and notifications on the medications' usage, breakage, waste and expiration. Further, the disclosed system and method utilizes tamper evident bags with unique identifier to protect and keep accurate track of the medications.

The invention relates to a water-soluble amino acid ester derivative of propofol and application thereof. Amino acid ester of the propofol has a structure with a formula (I), wherein R is shown in the description. The invention also relates a preparation method for a compound with the formula (I), a medicinal salt thereof, a compound-containing medicinal composition and application of the compound serving as narcotic medicines.

The invention discloses a nerve block injection test device. The device comprises a nerve block puncture needle, a liquid injection catheter, an injector, an injection pump and a treadle type filling injector; the liquid inlet end of the nerve block puncture needle is connected with the liquid outlet end of the liquid injection catheter; the liquid inlet end of the liquid injection catheter is connected with the liquid outlet end of the injector; the injector is clamped on the injection pump; the treadle type filling injector is connected with the injection pump through signal conveying lines. The device has the advantages that when in implementation, a doctor holds an ultrasonic probe by one hand so that a part which needs anesthetization on a patient body can develop on a computer, the doctor holds the nerve block puncture needle by the other hand to conduct puncture on the corresponding part which needs anesthetization, and then the filling injection of narcotic liquid can be completed by stepping on the corresponding treadle type filling injector, so that the troubles can be omitted that the doctor talks to another doctor and guides another doctor to hold the injector and push the narcotic medicine to a narcotic part, then the injection test work can be completed only by one doctor, and thus the labor can be saved, and the working efficiency can be improved.

The invention relates to a system for delivering anesthesia drugs to a patient. The system comprises means for feeding anesthesia drugs to the patient treated, a measuring device for measuring at least one parameter relating to the effects of the anesthetic drugs fed to the patient, a patient monitor to show the results measured by the measuring devices, and feeding means for feeding patient demographics to the system. The system further comprises means for visual planning of the anesthesia drug delivery before the drugs are actually fed. The system can also comprise means for anesthesia management for drug interaction during the treatment.