54 results about "Amitriptyline" patented technology

A method is presented for the preparation of topically applied compositions used for the treatment of regional pain, especially sympathetically mediated pain. NMDA receptor antagonists, such as ketamine or dextromethorphan, and one or more tricyclic antidepressants, such as amitriptyline, in combination, are employed.

The present invention provides compositions for transdermal pain relief. According to one embodiment, a transdermal composition for the relief of pain in a subject comprising: amitriptyline, clonidine, ketamine and an anti-inflammatory in a base having at least ten percent (10%) lecithin isopropyl palmitate oil (lipoil).

Tension-type headache is treated by interacting smith neuronal transmission in relation to pain in connection with headache in a way which prevents or decreases sensitization of second order nociceptive neurons. In particular, treatment is performed by administration of an effective amount of a substance which prevents or decreases central sensitization. Important examples of such substances are substances which interact with glutamate neurotransmission, such as glutamate receptor antagonists, such as NMDA receptor antagonists, such as MK-801 or Amitriptylline or Imipramine or Desipramine or Mirtazaprine or Venlafaxine. Other examples are substances which interact with nitric oxide, such as nitric oxide synthase (NOS) inhibitors, such as L-NMMA or L-NAME or L-NIO or L-NNA. According to a broader aspect of the invention tension-type headache is treated by administration of substances which are effective in preventing or decreasing pain in connection with tension-type headache, such as the substances mentioned above. An additional aspect of the invention relates to treatment of tension-type headache by administration of substances which substantially inhibit the activity of nitric oxide synthase (NOS), such as NOS inhibitors, such as L-NMMA or L-NAME or L-NIO or L-NNA.

The present invention relates to cyclobenzaprine analogs and amitryptilene analogs, including deuterated forms useful for treatment or prevention of symptoms associated with post-traumatic stress disorder.

The present invention relates to the use of amitriptyline as an inhibitor of connexin hemichannels (HC) in the Central Nervous System (CNS). This HC-blocking agent is advantageously used to treat disorders involving misregulated HC (notably neuropathic pain, neurodegenerative disorders, ischemic brain injury and inflammatory intestinal conditions). Additionally, the invention provides a method to enhance the therapeutic effect of amitriptyline for its common indications. The method of the invention involves combining amitriptyline with another HC-blocking agent, mefloquine.

The present application to an invention describes a pharmaceutical composition with a fixed dose of paracetamol and specifically amitriptyline supported by the pharmacological interaction and safety studies that show its synergy for the anti-allodynic and the mechanical anti-hypernociceptive effects and for the reduction of persistent pain, proportions, safety and neuroprotective capacity. This isaimed to the treatment of mixed pain due to cancer that can be incorporated as another option in the strategy of the WHO analgesic ladder at step 1 for the treatment of mild pain. However, it can also be included in higher steps associated with opioids for the treatment of pain of greater intensity and potentially decrease dose escalation and adverse effects such as tolerance and hyperalgesia.

The invention mainly relates to the technical field of planting, and discloses a handling method of accelerating germination of a seed of fructus lycii. The processing method comprises the steps of seed soaking, seed drying, seed dressing and germination acceleration, and soil preparation and seed sowing. According to the handling method of accelerating germination of seed of fructus lycii, the method is simple, the bud ratio is 98%, time for germination is shortened to 4-5 days after the sowing, plant efficiency is obviously improved, and economic income is improved by 16.2%; the seed of fructus lycii is subjected to soaking through an amitriptyline solution, nutritional contents are provided, not only anti-microbial and insect killing effects are achieved, seed coat softening is also promoted, entering of nutritients and moisture are accelerated, and seed germination is promoted; after the seed is subjected to drying and surface skin moisture reducing, seed germ vigour is promoted at high temperature, stress resistance is improved, and germination rate is improved; bactericide is added into the dried seed, wherein the bactericide is extracted from pure plants, and can the bactericide can not only prevent bacteria and kill insects, but can also provide nutrients necessary to the germination of the germ, and thus the germination of the seed is accelerated.

The invention provides a medicament for treating gastropathy, which is prepared from (by weight ratio) 18-22 wt% of notoginseng, 18-22 wt% of peach kernel, 18-22% of chicken's gizzard-skin, 3-4% of borax, 28-35% of pepsin, 5-6% of potassium bromide, 1.8-2.2% of amitriptyline powder, and 0.5-0.75 times of bee honey.

Alternatives described herein relate to methods for detecting, identifying, and / or diagnosing eating disorders, nutritional deficiencies, and / or malnutrition, including conditions such as bulimia nervosa and / or anorexia nervosa, by using X-ray diffraction on a sample of a tested subject's hair. In some alternatives, once an eating disorder, nutritional deficiency, or malnutrition is detected, identified, or diagnosed using the X-ray diffraction approaches set forth herein, a subject identified as having an eating disorder, nutritional deficiency, or malnutrition is provided counseling for the disorder and / or a medicament to treat, inhibit, or ameliorate said eating disorder or malnutrition, including Prozac, ami trip tyline, fluoxe tine, imipramine, Nardil, Tofranil, desipramine, Sarafem, Norpramin, and / or phenelzine.