The invention relates to a bactericidal composition with active ingredients to be pyrazole-kresoxim-methyl and thiram, and belongs to the bactericidal composition pesticide technology field. The bactericidal composition contains the active ingredients to be the pyrazole-kresoxim-methyl and the thiram, the weight ratio of which are 1:40-40:1 and the weight percentages are 1%-90%; and the bactericidal composition can be prepared into wettable powder, water dispersible granules, a suspending agent, aqueous emulsion, micro-emulsion, or other formulations. The bactericidal composition at least contains a carrier and an accessory ingredient, wherein at least one is a surface active agent which can be an emulsifier, a dispersant, a humectant or a penetrant. The carrier can be water, organic solvent or latent solvent, and filling material according to the different preparation formulations. A stabilizing agent, a thickening agent, a defoaming agent, a cementing agent and other functional accessory ingredients can be added when necessary. The bactericidal composition can be used for preventing and curing a plurality of plant diseases caused by oomycetes, ascomycetes, basidiomycetes, deuteromycetes, and so on, so as to play an important role in enhancing effects, curing diseases, reducing cost, delaying pesticide resistance, etc.