134results about How to "Easy adhesion" patented technology

The invention generally relates to polymeric particles suitable for transporting bioactive agents across mucosal barriers. The invention also relates to methods of making and using those polymeric particles.

Specialization of the end(s) or host tissue contact points of biocompatible scaffolds brings a functionality to the scaffold that facilitates the dual function of inducing new tissue formation and facilitating attachment and site-specific tissue formation at the scaffolds' functionalized points of fixation.

Particular aspects provide novel devices for bone tissue engineering, comprising a metal or metal-based composite member/material comprising an interior macroporous structure in which porosity may vary from 0-90% (v), the member comprising a surface region having a surface pore size, porosity, and composition designed to encourage cell growth and adhesion thereon, to provide a device suitable for bone tissue engineering in a recipient subject. In certain aspects, the device further comprises a gradient of pore size, porosity, and material composition extending from the surface region throughout the interior of the device, wherein the gradient transition is continuous, discontinuous or seamless and the growth of cells extending from the surface region inward is promoted. Additional aspects provide a device for bone tissue engineering, comprising a metal or metal-based composite member/material comprising an interior porous structure, wherein the pore size, porosity and material composition is selected to provide a device having an optimal density and/or elastic modulus and/or compression strength for a specific recipient. Novel methods for fabricating the devices are also provided.

Assemblies, systems, and methods convey fluid from an internal wound site or body cavity by applying negative pressure from a source outside the internal wound site or body cavity through a wound drain assembly that is placed directly inside the internal wound site or body cavity.

The present inventors studied the effects of inhibiting the IL-6 signaling pathway on muscle cell growth. As a result, they discovered that, administering an IL-6 inhibitor can promote the adhesion, proliferation, and differentiation of satellite cells and therefore muscle regeneration.

The present invention provides novel hydrogels and methods of making and using such hydrogels. The present invention provides hydrogels that may be formed by the self-assembly of peptides in solution. Such self-assembly may be brought about by a change in one or more characteristics of the solution. Characteristics of the solution that may be changed include pH, ionic strength, temperature, and concentration of one or more specific ions. In addition, hydrogels of the invention may be disassembled by changing one or more characteristic of the hydrogel such as pH, ionic strength, temperature, and concentration of one or more specific ions.

Disclosed herein are methodologies and compositions for coating materials, which can be used in a variety of biological applications.

The present invention is directed to a novel method for preventing or treating respiratory infections and acute otitis media in infants. The method comprises the administration of a therapeutically effective amount of a Bifidobacteria strain and an adherence-promoting probiotic, such as LGG, to the infant.

A surgical drain device includes a matrix of biodegradable polymer material and a plurality of drain tubes attached to the matrix. The device is implanted within a surgical wound to treat the presence of seromas, for example, and is used to promote drainage, tissue adhesion, and wound closure. The drain tubes converge into a common collection tube that leads wound fluid outside the body under gravity feed or negative pressure applied to the collection tube. The matrix contains an array of apertures that allow tissue contact across the device. A preferred embodiment comprises a tissue anchoring system including anchor elements such as hooks or barbs. The device can be used with a negative pressure system to further improve the drainage band can also be used with a wound dressing. The device and systems containing the device are particularly useful to promote the healing of surgical wounds from abdominal surgery.

Assemblies, systems, and methods convey fluid from an internal wound site or body cavity by applying negative pressure from a source outside the internal wound site or body cavity through a wound drain assembly that is placed directly inside the internal wound site or body cavity.

The invention discloses a bending-twisting conversion type ultrasonic torsion vibration transducer which comprises a bending-twisting vibrating body(1), a drive component (2) and a back cover (3) of the transducer; the drive component (2) is arranged between the bending-twisting vibrating body(1) and the back cover (3) of the transducer, and moreover, an A pretighting bolt (33) passes through the through hole of an A end cover (31), an A through hole (22) and an A pretighting screw hole (121) in turn through to arrange the A end cover (31) and an insulating block (21) on the A top surface (107) of the bending-twisting vibrating body(1); an B pretighting bolt (34) passes through the through hole of an B end cover (32), an B through hole (23) and an B pretighting screw hole (151) in turn to arrange the B end cover (32) and the insulating block (21) on the B top surface (108) of the bending-twisting vibrating body(1). A pair of bending vibrations with the same frequency swings and opposite vibrating directions generated by corresponding two groups of piezoelectric ceramics drive elements are amplified and transmitted to a converter by two bending arms; two bending vibrations are coupled and converted into a coupling torsion vibration (63) through a mode converter; a torsion vibration (64) is obtained and output after being amplified by an amplitude transformer (101), thus obtaining ultrasonic torsion vibration by a simpler mode.

The present invention relates to scaffolds which can be used as medical devices for guided tissue regeneration and repair, in particular the invention is directed to a scaffold comprising fibres having a mean fibre diameter of between from about 1.2 to 4.0 microns, wherein the fibres comprise a glycolide. The invention further relates to the use of the scaffolds for the selective capture of cell populations for a cell source material.

The invention relates to an ice coating resistance paint which has the following main components: 20-70% of fluoropolymer resin, 1-7% of fluorine-containing surfactant, 2-7% of aluminum hydroxide, 1-5% of nano-powder, 0.1-2% of metallic drier, 20-80% of solvent. The ice coating resistance paint composition can perform the best effect in ice coating resistance when applied to high-voltage cables, iron towers, communication lines and the like, thus reducing adhesive force of the ice on the surface of base material and ice concentration on the surface of the base material; then under the effect of wind and natural force, the ice is easy to be separated from the surface of the base material. The ice coating resistance paint has very good binding force on metal matrix, relatively high thermal conductivity, what is more, the outer surface of the paint features low surface tension, high hydrophobicity and ice-phobic property, thus reducing hydration adhesive force at utmost and facilitating the ice to fall off extremely easily and realizing the aim of preventing ice-forming and removing the ice. The method features simple and easy feasibility in engineering, convenient control, relatively low cost and good using effect.

The present invention relates to a polyurethane-coated (PU-coated) spandex fabric-fused midsole, and an apparatus and method for manufacturing the same, which allow a shoe midsole to be easily and conveniently manufactured through a single automatic process, and allows a PU-coated spandex fabric to be easily fused to a surface of the midsole in the process of manufacturing the midsole. For this purpose, there is provided a polyurethane-coated (PU-coated) spandex fabric-fused midsole manufacturing apparatus including: a central axis rotated by a driving force of a motor; a rotary disc fitted on the central axis to be rotated together with the central axis; a plurality of midsole forming mold units, which are mounted on the outer ends of support members radially extending from the outer circumference of the rotary disc, respectively; a PU-coated spandex fabric supply apparatus installed above the trace of rotation of the midsole forming mold units to provide a PU-coated spandex fabric to each of the midsole forming mold units; vacuum means installed between the rotary disc and the midsole forming mold units to vacuum the inside of a midsole forming mold unit supplied with a PU-coated spandex fabric to such an extent that the PU-coated spandex fabric comes into close contact with the inner surface of the midsole forming mold unit; a resin introducing apparatus installed outside of the trace of rotation of the midsole forming mold units to introduce polyurethane (PU) resin into the midsole forming mold unit having the PU-coated spandex fabric film in contact with inner surface thereof; and a foam-molded product removal apparatus installed outside of the trace of rotation of the midsole forming mold units to remove a foam-molded product formed by foaming the polyurethane resin introduced into the midsole forming unit by leaving the polyurethane resin in the midsole forming mold unit at a predetermined temperature for a predetermined length of time.

A method of providing a molding article with a plush surface is provided. The method includes providing a flocked transfer, securing the transfer in place in a mold, and molding the article such that the transfer is embedded in the surface of the article. The article can be injection molded.

An optical system of a helmet displayer comprises a micro displayer, a bonding lens and an optical combiner. The micro displayer and the bonding lens are bonded integrally, the optical combiner comprises two tightly-adhered right-angle prisms forming a 45-degree angle and a concave-surface reflecting mirror, a narrow-band high-reflective optical surface is located at the bonding position of the two right-angle prisms and forms a 45-degree angle respectively with the horizontal optical axis and the vertical optical axis, the concave-surface reflecting mirror and the right-angle prisms are bonded integrally, and the concave surface is the high-reflective optical surface. Light beams are emitted from the micro displayer, are converged through the bonding lens, enter the optical combiner and pass through the narrow-band high-reflective optical surface, then transmitted light beams are converged through the high-reflective optical surface again, and reflected light beams become parallel light beams after the light beams pass through the narrow-band high-reflective optical surface again. An exit pupil is located at the position of a pupil of one human eye, extraneous light enters the optical combiner and passes through the narrow-band high-reflective optical surface, and then the transmitted light beams enter the pupil of one human eye. The optical system of the helmet displayer has the advantages of being compact in system, convenient to correct, good in aberration correction and high in reliability.

Provided is a cleaning sheet adapted to clean a surface of a heating roll in a fixing device, which causes a recording sheet bearing a toner image formed of a magnetic toner containing a magnetic material to pass through the fixing device under a state in which the recording sheet is in press contact with the surface of the heating roll having arranged thereon a contact component in contact with the surface of the heating roll and heated to a fixing temperature to rotate, to perform fixing of the toner image, including a synthetic resin sheet with a thickness of 100 μm or more, which is made of a thermoplastic resin with a melting point higher than the fixing temperature and Rockwell hardness of M60 or more or thermosetting resin with Rockwell hardness of M60 or more.

A process for producing a collagen/hydroxyapatite (HA) composite scaffold comprises the steps of forming a homogenous suspension of collagen and HA in an acidic solution, lyophilising the suspension until a desired final freezing temperature is reached to produce the composite scaffold, and optionally cross-linking the composite scaffold, wherein the ratio of HA to collagen is at least 1:10 (w/w). Also provided is a collagen/hydroxyapatite (HA) composite scaffold comprising a homogenous distribution of hydroxyapatite within a porous, crosslinked, collagen matrix, wherein the ratio of HA to collagen is at least 1:10 (w/w). Suitably, the composite scaffold has a porosity of at least 99% (v/v), and a compressive stiffness of at least 0.3 KPa. Composite scaffolds of the invention may be used to provide osteoconductive bone implants and tissue engineering implants.

In accordance with the present invention, a high intensity radiopaque contrast agent is disclosed. The agent may be coated on or incorporated within bulk material which may then be subsequently utilized to fabricate a radiopaque medical device. Primary effects through chemistry include higher radiopaque concentrations per unit weight of the radiopaque element or agent. Secondary effects include selective placement of the radiopaque elements which may further enhance the radiopacity of the device with reduced requirements of the radiopaque agent. Such a radiopaque contrast agent may be produced in various forms such as a dendrimer and/or incorporated as the end groups of polymeric chain. In addition one can incorporate biological and/or pharmaceutical agents in combination with the present invention.