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507 results about "Intestinal absorption" patented technology

Floating type pellets in stomach and preparation method thereof

The invention relates to the technical field of medicine, in particular to a stomach floating type pellet and a preparation method thereof. The stomach floating type pellet comprises a pellet core, a drug layer and a sustained-release layer; the density of the pellet is smaller than 1g / cm<3>, so that the drug can float in the stomach, sustainably release the drug ingredients; stomach floating type capsules can be prepared by loading the pellets into capsules. The preparation type is suitable for drugs mainly absorbed in the stomach, in particular to the drugs that are absorbed better in the stomach than in the enteric canal. When the drugs are prepared into stomach floating type pellets or stomach floating type capsules, compared with ordinary preparation, the times of administration is reduced and the relatively stable blood concentration of the drugs is kept in vivo, thus ensuring the sustained release of the drugs, improving the bioavailability and reducing the dosage. At the same time, as the stomach floating type pellet is a granose system, the drug release behavior is the collective behavior of each pellet, so that coating failure of a plurality of pellets can not lead to failure of the whole dosage, thus having higher safety. The sustained-release pellet is prepared by adopting general technique and is easy for realizing industrial production.
Owner:特康药业集团有限公司

Method for preparing mixed type nucleotide feed addictive from yeast cell and application

The invention relates to a method for preparing a mixed-type nucleotide feed additive from yeast cells and applications of the feed additive, which belong to the technical field of the preparation of nucleotide feed additives from yeast cells. The method comprises the steps: using yeast cells as raw materials and combining a homogenization method and a salt method to break yeast cell walls ; separating the yeast cell walls, protein and other insoluble substances by centrifugation and fractional isoelectric crystallization; specially collecting RNA precipitates at special isoelectric points to obtain wet and crude nucleic acid with the purity of 70 percent; dissolving the wet and crude nucleic acid in water, using high-activity phosphodiesterase from malt roots to carry out a high-efficiency directional enzymatic reaction; directly spraying, drying and crushing the solution after the enzymatic reaction to obtain the mixed-type nucleotide feed additive product comprising the protein content lower than 10 percent and four monosomic nucleotides (AMP, GMP, CMP and UMP) larger than 60 percent. After the feed additive is applied to animal feed, the intestinal absorption function of animals can be notably improved, the growth of the animals is stimulated, and the immune function, the antiviral capability and the anti-stress capability of the animals are improved.
Owner:江苏省苏微微生物研究有限公司 +2

Nanoparticle compositions and methods for improved oral delivery of active agents

Nanoparticles, compositions, and methods for the improved uptake of active agents are disclosed herein. The compositions contain a monodisperse population of nanoparticles, preferably including an active agent, where the nanoparticles are formed from a polymeric material possessing specified bioadhesion characteristics. Following enteral administration, preferably oral administration, the nanoparticles exhibit total intestinal uptakes of greater than 20%, preferably greater than 45%, more preferably greater than 65%. When compared to uptake of the same composition in the absence of the bioadhesive polymeric material, the nanoparticles have significantly increased uptake with intestinal uptake of the increased by more than 100%, preferably even greater than 500%. Further disclosed herein is a method of producing multi-walled nanoparticles, as well as methods of using thereof. Multi-walled particles prepared using the method disclosed herein are useful for controlling the release of active agents.
Owner:BROWN UNIVERSITY

Feed fermentation agent and fermented feed

The invention discloses a feed fermentation agent and a fermented feed, the feed fermentation agent includes the following components by mass: 20-25% of pichia pastoris, 15-20% of lactobacillus, 10-15% of enterococcus faecalis, 3-10% lactobacillus plantarum, 10-15% of cellobiose lactobacillus and 15%-25% a compound enzyme agent. The fermented feed is a fermented product of soybean meal, corn and wheat bran, mulberry-rich plants and a mixture of mulberry-rich plants and soybean meal by use of the feed fermentation agent, after fermentation of the soybean meal or corn or wheat bran and other traditional feed by use of the feed fermentation agent, harmful materials such as accumulated stool and the like cumulated in pig intestines can be decomposed and removed by cooperation of crude fiber in the traditional feed and microorganism, so that the intestinal absorption efficiency of nutrients can be provided.
Owner:郭旭华

Health-care food for improving moisture of skin and removing wrinkle

The invention discloses a health-care food for improving the moisture of skin and removing wrinkles, which is prepared by the following raw materials in parts by weight; 10-15 parts of collagen powder, 6-8 parts of soybean isoflavone, 3-5 parts of pearl powder, 3-5 parts of aloe extract, 3-5 parts of American ginseng extract, 3-5 parts of poria cocos extract, 3-5 parts of amur corktree bark extract, 2-3 parts of Chinese date, 1-2 parts of vitamin C powder, 3-5 parts of fructo-oligosaccharide, 3-8 parts of sodium carboxymethylcellulose, 1-5 parts of citric acid, 1-5 parts of malic acid and 5-20 parts of sucralose. The invention has the functions of internally expelling the toxin, tonifying the qi and nourishing the yin and replenishing the collagen lacked in human bodies by reasonably blending with the collagen powder, the soybean isoflavone, the pearl powder, the aloe extract, the poria cocos extract, the American ginseng extract, the amur corktree bark extract, the Chinese date and the vitamin C powder, thereby achieving the effects of water replenishing and wrinkle removal from inside to outside; and in addition, the raw materials of the fructo-oligosaccharide and the like are added, thereby the invention has the effects of adjusting tastes and promoting intestinal absorption.
Owner:山东森健生物科技发展有限公司

Liquid calcium soft capsules and preparation method thereof

InactiveCN103190615AHigh in calciumHigh intestinal absorption rateFood preparationNutritional statusPhysical well being
The invention relates to liquid calcium soft capsules and a preparation method thereof. The inclusion of the soft capsules is prepared from the following raw materials in parts by weight: 50 to 80 parts of calcium carbonate, 0.0001 to 1 part of vitamin D3, 20 to 50 parts of soybean oil, and 15 to 30 parts of beeswax. The preparation method comprises the following steps of: preparing capsule bodies by using gelatin, glycerol and purified water as capsule body raw materials; mixing a mixture of the calcium carbonate, the vitamin D3, the soybean oil and the beeswax for 20 to 40 minutes, and slowly milling the mixture for 1 to 3 times through a colloid mill to obtain the uniformly mixed inclusion; and pressing, sizing, washing, drying, sorting and packing the inclusion and the capsule bodies, thus obtaining the liquid calcium soft capsules. Compared with the prior art, the liquid calcium soft capsules have the advantages that the calcium carbonate has the advantages of high calcium content, high intestinal absorption, high dissolubility, low price and the like compared with other calcium agents, so the soft capsules are beneficial to absorption of active ingredients; and the soft capsules can simultaneously supplement calcium and vitamin D, are convenient to administrate, improves the nutritional status of human bodies, and promotes the health of the human bodies.
Owner:SHANGHAI SPRING TANG BIO PROD

Total nutrient formula food for gastrointestinal malabsorption

The invention provides a total nutrient formula food for patients with gastrointestinal malabsorption to eat, a specific total nutrient formula food or a non-total-nutrient formula food. According to the requirements of general principles of the special medical use formula food, the formula is developed by combining with the constitutive characters of the patients with gastrointestinal malabsorption and synthesizing with the research results of advanced physiology, medicine, nutriology, clinical application and the like in Harvard University at present according to the essence theories (simultaneous recuperation of the liver, the spleen and the kidneys) of supplement in digestion and balanced recuperation in the traditional Chinese medicine. According to the total nutrient formula food, essence of more than ten medicinal and edible traditional Chinese medicine extracts, a plurality of probiotics and prebiotics are taken as main raw materials, and oligopeptide, amino acid, water-soluble dietary fiber, multi-vitamin and composite minerals are taken as auxiliary materials, the total nutrient formula food not only can meet the nutritional requirements of the patients with gastrointestinal malabsorption as a single nutrient source, but also can have the efficacies of invigorating the stomach and helping digestion, warming the middle warmer and rectifying the spleen, tonifying the stomach and promoting fluid, tonifying the spleen and nourishing the stomach, helping digestion and eliminating indigestion, resolving dampness and activating the stomach, and preventing and treating gastrointestinal malabsorption.
Owner:胡安然

Probiotic fermentation dendrobium officinale protocorm composition and preparation method thereof

The invention discloses a probiotic fermentation dendrobium officinale protocorm composition and a preparation method thereof. The preparation method comprises the steps that dendrobium officinale protocorm is dried, smashed into powder and immersed with water, glucose, peptone, yeast extract, yeast powder and a sweetening agent are added, inorganic salt is added, probiotic fermentation treatment is carried out after sterilization, polydextrose and fructo-oligosaccharide syrup are added, and the composition is prepared. The dendrobium officinale protocorm is subjected to high-pressure and high-temperature extraction after being smashed, and the extracting rate of effective ingredients of the raw materials is improved; multiple strains of probiotics are utilized for batch fermentation, the effective ingredients become active matter capable of being easily absorbed by the intestinal tract, and the utilization rate is improved. The composition has the effects of improving immunity, resisting tumor, oxidation, scavenging free radical, lowering blood fat and blood pressure, adjusting balance of intestinal flora, improving the gastrointestinal function and the like.
Owner:SANZHU FUER PHARMA

Preparation method of dendrobium officinale fungus fermented product, fermented product and application of fermented product

The invention discloses a preparation method of a dendrobium officinale fungus fermented product, the fermented product and an application of the fermented product. The preparation method of the dendrobium officinale fungus fermented product includes the steps of dendrobium officinale preparation, strain activation, liquid seed culture, dendrobium officinale fungus fermentation and fermented product processing. The fermented product is obtained by the preparation method of the dendrobium officinale fungus fermented product. The application comprises that the dendrobium officinale fungus fermented product is used for preparing food, health food, cosmetics and / or drugs. Dendrobium officinale is fermented with medicinal and edible fungi containing cellulose and other substances, dendrobium cellulose and the like are decomposed into small-molecular carbon sources, and the beneficial ingredients of the dendrobium officinale are retained; and moreover, the fermented product has mellow mouthfeel, has both faint scent of the dendrobium officinale and unique flavor of the fungi, also is rich in fungal polysaccharides, saponins, polyphenols, flavonoids and other active substances; the effective ingredients are easily absorbed in intestines, and has the efficacies of improving immunity, resisting tumor, resisting oxidation, reducing blood fat and blood pressure, regulating the balance ofintestinal microflora and the like.
Owner:YUNNAN UNIV OF TRADITIONAL CHINESE MEDICINE +2
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