1127results about How to "Retain activity" patented technology

Modified human growth hormone polypeptides and uses thereof are provided.

The present invention encompasses albumin fusion proteins. Nucleic acid molecules encoding the albumin fusion proteins of the invention are also encompassed by the invention, as are vectors containing these nucleic acids, host cells transformed with these nucleic acids vectors, and methods of making the albumin fusion proteins of the invention and using these nucleic acids, vectors, and / or host cells. Additionally the present invention encompasses pharmaceutical compositions comprising albumin fusion proteins and methods of treating, preventing, or ameliorating diseases, disordrs or conditions using albumin fusion proteins of the invention.

Antimicrobial compounds from Bacillus subtilis for use against animal and human pathogens. A novel strain of Bacillus subtilis was isolated from the gastrointestinal tract of poultry and was found to produce a factor or factors that have excellent inhibitory effects on Clostridium perfringens, Clostridium difficile, Campylobacter jejuni, Campylobacter coli, and Streptococcus pneumoniae. The factor(s) retain full viability and antimicrobial activity after heat treatment. The invention provides a method of treatment of pathogenic microorganisms including C. perfringens.

The invention relates to an innocent treatment method for animal carcasses died of illness and organic wastes. The innocent treatment method comprises the following steps: collecting to-be-treated materials of animal carcasses died of illness and organic wastes, then, mixing the to-be-treated materials and auxiliary materials as organic matters including wood flour and rice husk, and next, supplementing water until the water content is up to 50-60%; adding a compound microorganism preparation into a treatment tank; carrying out micro-biological degradation so as to ensure that main components such as the animal carcasses died of illness, various organic wastes and the like can be completely degraded within 24 hours and can be processed into an available organic fertilizer. The innocent treatment method is reasonable in process, simple and convenient in operation, energy-saving, environment-friendly, pollution-free and capable of utilizing the animal carcasses died of illness and the organic wastes as fertilizers.

The present disclosure relates to the preparation and deletion mutants of chondroitinase proteins and their use in methods for promoting the diffusion of therapeutic composition into tissues and their use for neurological functional recovery after central nervous system (“CNS”) injury or disease.

The present invention encompasses albumin fusion proteins. Nucleic acid molecules encoding the albumin fusion proteins of the invention are also encompassed by the invention, as are vectors containing these nucleic acids, host cells transformed with these nucleic acids vectors, and methods of making the albumin fusion proteins of the invention and using these nucleic acids, vectors, and / or host cells. Additionally the present invention encompasses pharmaceutical compositions comprising albumin fusion proteins and methods of treating, preventing, or ameliorating diseases, disorders or conditions using albumin fusion proteins of the invention.

The present inventors revealed that deamidation of an antibody can be suppressed without influencing its activity by substituting a glycine that is located adjacent to an asparagine with another amino acid.

The invention discloses a waste slurry recycling and reusing technology of a concrete mixing station. The waste slurry recycling and reusing technology of the concrete mixing station comprises the following steps: firstly pre-treating waste slurry of the concrete mixing station, and maintaining the activity of a cementing material in the waste slurry; then conveying the waste slurry from a settling pond to a pre-homogenizing pond, adding water and stirring for carrying out waste slurry pre-homogenization; filtering the obtained homogenous waste slurry through a filter screen, and conveying the homogenous waste slurry to a burdening and stirring tank; metering and stirring cement, a mineral admixture, water, a water reducing agent, an early strength agent and an exciting agent according to a proportion to prepare concrete slurry, conveying the obtained concrete slurry to a foaming machine to prepare foam concrete, pouring the foam concrete in a mold, standing, demoulding, and maintaining, thus obtaining a regenerated foam concrete product with the dry density level of 600 to 800 kg / m<3>. According to the waste slurry recycling and reusing technology disclosed by the invention, the problems of waste of land resources, environment pollution and increment of running cost of the concrete mixing station due to backfilling of the waste slurry of the concrete mixing station can be solved, qualified regenerative products can be generated, and the waste slurry recycling and reusing technology is suitable for being popularized and applied.