73results about How to "Improve tissue repair ability" patented technology

An injectable decellularized fat-matrix microparticle and applications thereof in implants are disclosed. The microparticle is prepared by rinsing, disinfecting and rising fat mass, performing repeated freezing-thawing, cutting the fat mass into slices, soaking the slices, degreasing, decellularizing, performing freeze-drying, and performing low-temperature grinding. The microparticle can be cooperated with an implant auxiliary and adopted as an injectable decellularized fat-matrix microparticle implant. The microparticle has advantages of good biocompatibility, capability of promoting tissue regeneration, and the like. As the microparticle has a three-dimensional structure, the microparticle can be adopted as a support for supporting tissue and cell growth. Active components of the microparticle can induce and regulate cell adhesion, growth, proliferation and differentiation and can promote tissue repairing and regeneration. The implant can be adopted as a minimally invasive plastic injection implanting material, and the implant has a filling function and a tissue repairing function as the natural three-dimensional structure and a lot of the active components of fat are preserved.

The invention discloses a carbon nano tube / collagen based composite material and a preparation method of the composite material. The composite material comprises collagen protein and carbon nano tubes, wherein the content of the collagen protein is 96.0-99.8 percent by mass percentage, and the content of the carbon nano tubes is 0.2-4.0 percent by mass percentage. According to the invention, the obtained carbon nano tube / collagen based composite material is provided with favorable biocompatibility, tissue repair property and extremely low immunogenicity; the required raw materials are easy to get; the conditions of the preparation technology are milder; and the composite material is provided with wide popularization and application value.

The invention discloses a preparation method for a drug-loadable tissue repairing membrane. The drug-loadable tissue repairing membrane comprises an electrospun fibrous membrane main body, at least one hermetic drug storage chamber formed in the electrospun fibrous membrane main body and a drug storage medium arranged in the drug storage chamber, wherein the electrospun fibrous membrane main body is prepared from a hydrophobic degradable material, and the drug storage medium is prepared from a hydrophilic degradable material. According to the tissue repairing membrane in the invention, the drug storage medium is wrapped in the electrospun fibrous membrane main body, and a drug solution can be injected into the drug storage medium before usage of the tissue repairing membrane so as to realize the drug loading and sustained drug releasing functions of the tissue repairing membrane, so the tissue repairing membrane is simple and convenient to use and prevents destroy of factors like organic solvents in conventional drug loading methods to drugs; moreover, the tissue repairing membrane can realize in-situ long-term stable drug delivery during tissue repairing, does not need to take out, is simple to operate and has good clinical application value in the field of tissue repairing.

The invention provides a spidroin tissue repair material. The spidroin tissue repair material is membranoid substance containing spidroin, the inside average hole density is 1-2000 / mm<2>, and the average hole size is 1-300 [mu] m. The spidroin tissue repair material is characterized in that the membranoid substance contains the following raw materials in parts by weight: 80-90 parts of spidroin solution, 4-6 parts of spidroin nanofiber solution, 4-5 parts of paracetamol slow-release microcapsules, and 1-2 parts of essential oil. The invention relates to the fields of biological materials and spidroin. A biological material for repairing the damaged large tissue and complicated organs needs to have the capacity of promoting the formation of the blood vessels for enabling the large tissue and the complicated organs to have the biological function. But in the prior art, mostly, only the pure fibroin repair materials are available, the ideal blood vessel formation promoting effect and tissue repairing function are difficult to realize, while the tissue repair material prepared by adopting the scheme provided by the invention has the good tissue repairing effect.

The invention discloses a plant growth monitoring device which comprises a box. An industrial control computer and a collecting hopper are arranged at the top of the box, the collecting hopper is usedfor collecting rainwater and connected with the inner bottom of the box through a conveying pipe, the inside of the box is divided into a cultivation chamber and a drainage chamber by a division plate, the side wall of the conveying pipe in the cultivation chamber supplies water for plants in the cultivation chamber through a splitter pipe, and a splitter plate is arranged on the lower portion ofthe splitter pipe. Plant cultivation humidity can be controlled, the air quality of a cultivation environment is improved, plant growth is accelerated by a pruning mode, and growth quality is improved by the pruning mode.

The invention relates to an artificial nerve sheath hydrogel repairing system as well as a preparation method and application thereof. The artificial nerve sheath hydrogel repairing system is prepared from the following raw materials in parts by weight: 2 to 3 parts of gelatin, 0.5 to 1 part of methacrylic anhydride modified gelatin, 30 to 35 parts of acrylic acid, 1 to 1.5 parts of dopamine grafted acrylic acid, 6 to 8 parts of tannic acid and 1 to 1.6 parts of methacryloyloxyethyl trimethyl ammonium chloride. The bionic artificial nerve sheath hydrogel repair system is prepared through 3D polymerization under the condition of thermal initiation by adjusting the content of each component. Compared with the prior art, the prepared artificial nerve sheath hydrogel repair system has good stability and excellent biocompatibility, has good repair and regeneration effects on cut sciatic nerves of rats, provides a new method for development of a repair system of damaged nervous tissues, and has wide application prospects. Wide application prospects are realized.

The invention provides a cell culture medium, a preparation method and application, and belongs to the technical field of cell culture. The cell culture medium is prepared from a basic culture medium,cytokines, hormones, proteins, biogenic amines, an inhibitor and solution declining elements, wherein the cytokines, the hormones, the proteins, the biogenic amines, the inhibitor and the solution declining elements are added into the basic culture medium. The basic culture medium can effectively maintain the stability of the cell environment while maintaining the activity of the cells. By addingthe cytokines, the hormones, the proteins, the biogenic amines, the inhibitor and the solution declining elements into the basic culture medium, on the one hand, through the synergy between the components, animal-derived components in a traditional culture medium can be replaced, the stability of the cell culture medium can be ensured, and the risks of disease transmission and immune response arereduced; and on the other hand, the components cooperate with one another other, the cell activity is maintained, cells can proliferate steadily and rapidly, the primary separation efficiency of thecells is greatly improved, and the self-renewal and tissue repair capabilities of the cells are improved.

The invention discloses a traditional Chinese medicine composition for treating cancer and a preparation method thereof. The traditional Chinese medicine composition comprises oldenlandia diffusa, sculellaria barbata, taraxacum mongolicum, bunge corydalis herb, radix sophorae tonkinensis, common andrographis herb, folium mori, semen coicis, corns, millet and honey according to certain weight ratio. The traditional Chinese medicine composition has the efficacies of eliminating cancer, clearing heat and detoxicating, eliminating carbuncle and removing stasis, dissolving stasis and stopping pain, strengthening the body resistance and eliminating pathogenic factors as well as treating cancer with medicaments and food and can be used for effectively treating cancer.

The invention relates to a customized medical porous renewable handle-free shoulder joint humerus head implantable prosthesis with a cage. The method comprises the following steps: scanning a shoulder joint of a patient by using CT to obtain CT tomographic image data of humerus, and establishing a three-dimensional model conforming to a shoulder joint stemless cage and a humerus head according to the CT tomographic image data; under the condition that the grain size is controlled under the assistance of ultrasonic equipment, mixing multiple types of medical nano-metals as a base material of the handle-free cage, and printing the porous handle-free cage layer by layer; printing a high-strength biological ceramic humerus head by using various medical nano biological ceramic powder; and then carrying out electron beam irradiation treatment and adding a strontium-loaded micro-nano coating to finally obtain a finished product. The design of innovative combination of the 3D porous material and the bone cage technology is adopted, infiltration growth of sclerotin is achieved, a backbone is not needed, implantation is more convenient, complications related to the humerus component handle in a revision operation where the humerus component handle needs to be removed are avoided, and the success rate of the operation is increased; the humerus head obtained by the invention also has higher strength, corrosion resistance and biocompatibility.

A polylactic acid composite biological tissue repair material and a preparation method thereof belong to the field of composite biological materials. The polylactic acid composite biological tissue repair material consists of the following raw materials by mass percent: 30-35% of polylactic acid, 20-25% of mesoporous nano-bioactive glass, 35-45% of tetrahydrofuran, 3-5% of a Chinese herb extract, 1-2% of a green tea extract, 1-2% of sodium hyaluronate and 1-2% of allantoin. The polylactic acid composite biological tissue repair material has favorable mechanical performance and an excellent medicinal effect.

The invention relates to a preparation method of a tilapia skin collagen composite recycled fiber repair material, and belongs to the technical field of tissue repair material preparation, wherein the preparation method comprises: preparing tilapia skin collagen, preparing a bamboo fiber solution, preparing a recycled cellulose spinning liquid, and carrying out electrospinning to prepare the repair material. The prepared tissue repair material of the present invention has advantages of good antibacterial property, good mechanical property, good tissue repair property, and good drug adhesion.