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Preparation method for sheep placenta-regenerated fiber composite repair material

A technology for repairing materials and composite regeneration, which is applied in the fields of fiber chemical characteristics, single-component cellulose rayon, rayon manufacturing, etc. It can solve the problems of composite film uniformity, poor stability, tissue repair ability and drug adhesion. Improvement and other issues, to achieve the effects of good adhesion, excellent degradability, and increased porosity

Inactive Publication Date: 2017-08-04
孙博文
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, most of the existing technologies use regenerated cellulose and other materials to blend and freeze-dry to prepare composite films. The uniformity and stability of the composite films prepared by this method are poor, and the tissue repair ability and drug adhesion need to be further improved.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] A preparation method of sheep placenta composite regenerated fiber repair material, comprising the following steps:

[0028] Step 1: thaw the fresh sheep placenta, rinse it with normal saline, cut it into pieces, remove the fascia and blood vessels, prepare a homogenate with a mass concentration of 10% through a tissue homogenizer, centrifuge, collect the precipitate and freeze-dry it, after freeze-drying Grinding with a pulverizer, passing through a 60-mesh sieve to obtain sheep placenta powder;

[0029] Step 2: Take sheep placenta powder, add 80% by mass of deionized water and stir, pretreat at 90°C for 5 minutes, cool to 50°C, adjust pH to 7 with 0.2mol / L NaOH, add 1% by mass of protease , enzymolysis reaction for 20 minutes, after the reaction was completed, use a boiling water bath to inactivate the enzyme for 5 minutes, adjust the pH to neutral with NaOH / HCl after cooling to room temperature, centrifuge at 8000r / min for 20 minutes, collect the supernatant, and obt...

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PUM

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Abstract

The invention provides a preparation method for a sheep placenta-regenerated fiber composite repair material, belonging to the technical field of tissue repair materials. The preparation method comprises the following steps: preparation of sheep placenta extract; preparation of a milk protein solution; preparation of a regenerated-cellulose spinning solution; and electrostatic spinning for preparation of the repair material. The repair material prepared in the invention has good antibacterial properties, mechanical properties, tissue repairing performance and drug adhesion.

Description

technical field [0001] The invention belongs to the technical field of preparation of tissue repair materials, and in particular relates to a preparation method of a sheep placenta composite regenerated fiber repair material. Background technique [0002] As a natural biopolymer, cellulose has biodegradability, biocompatibility and unique physical, chemical and mechanical properties, and has become a research hotspot in the field of new biomedical materials. However, most of the existing technologies use regenerated cellulose and other materials to blend and freeze-dry to prepare composite films. The uniformity and stability of the composite films prepared by this method are poor, and the tissue repair ability and drug adhesion need to be further improved. . Contents of the invention [0003] In order to solve the problems in the prior art, the invention provides a preparation method of a sheep placenta composite regenerated fiber repair material with good tissue repair a...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): D01F2/00D01F1/10
CPCD01F1/10D01F1/103D01F2/00
Inventor 王吉鹏
Owner 孙博文
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