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Preparation method of periostracum cicada compound bioglass tissue repair material

A technology of bioglass and tissue repair, applied in tissue regeneration, textiles and papermaking, medical science, etc., can solve problems such as poor mechanical properties and poor drug adhesion, and achieve the effects of improving mechanical properties, increasing porosity, and improving medical properties

Inactive Publication Date: 2017-09-29
HEFEI CHUANGWO TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, in view of the existence of its amorphous silicon skeleton, bioglass still presents an amorphous form, poor mechanical properties, and poor drug adhesion, and its application in biomedical materials remains to be further developed

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] A preparation method of cicada slough composite biological glass tissue repair material, comprising the following steps:

[0023] Step 1: take 25g of cicada slough, crush it into coarse powder, cross a 60-mesh sieve, add 10 times its weight in distilled water to soak for 2 hours, reflux for extraction for 1.5 hours, and obtain filtrate 1 by suction filtration; add 8 times the weight of distilled water in the filter residue, Reflux extraction for 1 hour, and suction filtration to obtain filtrate 2; then add distilled water 6 times the weight of the filtration residue to the filter residue, reflux extraction for 1 hour, and suction filtration to obtain filtrate 3; combine filtrate 1, filtrate 2, and filtrate 3, and place at a temperature of 60°C under vacuum Concentrate under reduced pressure to 150g under the condition of 0.06Pa, filter with three layers of gauze to obtain the cicada slough extract;

[0024] Step 2: Remove the cocoons from the cocoons, put them into a bo...

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PUM

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Abstract

The invention relates to a preparation method of a periostracum cicada compound bioglass tissue repair material, belonging to the field of biological medicine materials. The preparation method comprises the steps of preparing a periostracum cicada extracting solution, preparing a silk fibroin nano-solution, preparing a bioglass solution, and carrying out electrostatic spinning, so as to obtain the repair material, wherein periostracum cicada has certain sterilization and antiphlogosis effects, silk fibroin is capable of changing the mechanical properties of the material, and bioglass is capable of changing the medical properties of the material. The tissue repair material prepared by virtue of the preparation method has good mechanical properties, tissue repair performance and drug adhesiveness.

Description

technical field [0001] The invention belongs to the field of biomedical materials, and in particular relates to a preparation method of a cicada slough composite biological glass tissue repair material. Background technique [0002] Since the discovery of bioglass, people have paid more attention to the influence of bioglass components on biological activity. The rise of nanotechnology has made people realize that structure also has an important impact on biological activity, and more attention has been paid to the effect of size effect and microscopic fine structure on the structure and performance of materials. The nano-bioglass and mesoporous bioglass developed and designed from the nano-scale have attracted the attention of scholars at home and abroad. Bioglass can activate cell genes, help to enhance cell proliferation and differentiation, and has osteoinductive and osteoconductive effects. However, in view of the existence of its amorphous silicon skeleton, bioglass ...

Claims

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Application Information

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IPC IPC(8): A61L27/36A61L27/10A61L27/22A61L27/54A61L27/18D01D5/00
CPCA61L27/3604A61L27/10A61L27/18A61L27/227A61L27/54A61L2300/252A61L2300/404A61L2300/41A61L2300/412A61L2430/02D01D5/0015C08L89/00C08L71/02
Inventor 王吉鹏
Owner HEFEI CHUANGWO TECH CO LTD
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