505results about How to "Speed ​​up the repair process" patented technology

A device for delivering fluid to a person including a reservoir for containing a fluid to be delivered to the person, a fluid transport device for dispensing fluid from said reservoir to the person, said fluid transport device including a proximal end in fluid communication with said reservoir and a distal end having a penetrating member for piercing the skin of the person to facilitate the delivery of fluid to the person through the fluid transport device, a housing containing said reservoir and said fluid transport device, said housing including an exit port for receiving said distal end of said fluid transport device upon injection of said distal end into said person and means for securing a first wall of said housing to the skin of the person, a injection activation device including a driving mechanism contacting said fluid transport device for driving said penetrating member from a first position within said housing, through said exit port to a second position, external to said housing and into the skin of said person, and an electrically driven actuator for activating said driving mechanism.

Cells grown on a microcarrier are separated from the microcarrier by enzymatically digesting the microcarrier. More specifically, chondrocytes may be grown on dextran microcarrier beadlets and then the beadlets digested using dextranase to separate the chondrocytes from the carrier. Cells can also be grown on chitosan microcarriers to be used for implantation. In addition, cells can be grown on polysaccharide polymers to be used as implant devices. Various polymers serve as scaffolds for cells to be used for implantation. The polymers can be used for cell culture as well as for preparing scaffolds useful for tissue replacement such as cartilage tissue.

The invention relates to the technical field of cosmetics, in particular to a natural plant extract composition and application thereof in the cosmetics. The natural plant extract composition is prepared from the following raw materials in parts by weight: 0.1 to 10 parts of plant stem cells, 2 to 10 parts of grapefruit extracts, 1 to 10 parts of radix asparagi extracting solution, 1 to 10 parts of gingko extracts, 5 to 10 parts of lucid ganoderma extracting solution, and 1 to 5 parts of burdock extracting solution. The natural plant extract composition provided by the invention not only has remarkable moisturizing and anti-aging effect, but also has the effects in removing acnes, adjusting grease secretion, resisting inflammation and relieving, and can be used for preparing moisturizing, anti-aging or acne-removing cosmetics.

An intracranial, light-emitting implant for providing therapy to a patient having Alzheimer's Disease.

A fixing device includes a substantially cylindrical metal member, a heater positioned to heat the metal member, an endless, flexible fixing member disposed rotatably around the metal member and heated by the metal member to heat and fix a toner image, a rotary pressing member disposed opposite the metal member and pressed against an outer circumferential surface of the fixing member to form a nip therebetween, and a stationary member disposed at an inner circumferential surface side of the fixing member and pressed by the pressing member via the fixing member to form the nip. At least when the fixing member is relatively moved toward the metal member during assembly of the fixing member with the metal member, the metal member includes at least one protruding portion protruding axially outward from an axial end of the metal member to guide the fixing member axially toward the metal member.

Method, system and apparatus for monitoring target tissue temperatures wherein temperature sensors are configured as passive resonant circuits each, with a unique resonating signature at monitoring temperatures extending below a select temperature setpoint. The resonant circuits are configured with an inductor component formed of windings about a ferrite core having a Curie temperature characteristic corresponding with a desired temperature setpoint. By selecting inductor winding turns and capacitance values, unique resonant center frequencies are detectable. Temperature monitoring can be carried out with implants at lower threshold and upper limit temperature responses. Additionally, the lower threshold sensors may be combined with auto-regulated heater implants having Curie transitions at upper temperature limits.

System method and apparatus for accurately carrying out the in situ heating of a targeted tissue. Small implants are employed with the targeted tissue which exhibit an abrupt change of magnetic permeability at an elected Curie temperature. The permeability state of the implant is monitored utilizing a magnetometer. The implants may be formed as a setpoint temperature determining component combined with a non-magnetic heater component to enhance the tissue heating control of the system. With the system, a very accurate quantum of heat energy can be supplied to a neoplastic lesion or tissue carrying infectious disease so as to maximize the induction of heat shock proteins. The system also may be utilized in conjunction with non-magnetic arterially implanted stents for the hyperthermia therapy treatment of restenosis and in conjunction with the mending of boney tissue.

Compositions and methods for enhancing repair of damaged DNA in skin cells. Topical compositions comprising at least one agent that upregulates circadian gene expression in skin cells and at least one non-circadian agent that delays mitosis in skin cells. Preferably, such compositions comprise one or more keratinocyte clock and per1 gene activators, along with SIRT1 or one or more sirt1 activators. More preferably, the sirt1 activator is a synergistic combination of specific peptidic sirt1 activators and resveratrol. Preferably, such compositions are easy to use, efficacious, cosmetically acceptable, chemically, thermodynamically and light stable, safe for topical use, have little or no side effects, and commercially feasible in a personal care marketplace.

Methods and compositions are provided for the treatment of articular cartilage defects and disease involving the combination of tissue, such as osteochondral grafts, with active growth factor. The active growth factor is preferably a composition containing at least one bone morphogenetic protein and a suitable carrier. The method results in the regeneration and / or functional repair of articular cartilage tissue.

A biomaterial for suturing comprising a physiologically compatible support material coated with a cellular population with proliferative and / or differentiation capacity, characteristics which facilitate the regeneration of the sutured tissue. This biomaterial for suturing not only brings together the two edges of an open wound, but also contributes actively to the healing process, thereby accelerating the tissue repair process. Also disclosed are methods for making the biomaterial and methods for using the biomaterials in therapy.

The invention relates to methods of enhancing repair of a cartilage and / or inducing formation of a cartilage by administering a cell which expresses a factor of the T-box family, which includes inter-alia the brachyury. In another embodiment, the invention relates to an engineered cell, which is transfected with a vector comprising a nucleic acid sequence encoding a factor of the T-box family, thereby expressing a factor of the T-box family. In another embodiment, the invention relates to compositions comprising a vector which comprises a nucleic acid sequence encoding a factor of the T-box family and in another embodiment the composition comprising cell which expresses a factor of the T-box family, which includes inter-alia the brachyury.

The invention relates to the field of artificial intelligence, in particular to a fiberboard quality classification method based on machine vision. The method includes: acquiring a fiberboard surface grayscale image; performing sliding window processing on the grey-scale map on the surface of the fiberboard to obtain a plurality of sliding window areas; calculating the smoothness of a central pixel point of the sliding window; taking the pixel point corresponding to the minimum smoothness as a target pixel point, and obtaining a plurality of target connected domains; obtaining gradient amplitudes of pixel points in each target connected domain to construct a corresponding gradient histogram, calculating the probability that each target connected domain is a defect area, and determining all defect areas; calculating the probability of each gray value as a standard gray value, and determining the standard gray value; and calculating the quality coefficient of the fiberboard according to the gray average value of each defect area, and classifying the quality of the fiberboard. By analyzing the glossiness of the surface image of the fiberboard, the defect that the spatial domain feature is not obvious can be detected, so that the detection result is more accurate, and the product classification accuracy and the repair timeliness are improved; and the production efficiency is effectively improved.

The present invention provides a bi-directional communication network which provides monitoring, data collection, and control of food service industry operations. The system includes a computer and control logic implemented by the computer which may be configured to perform various tasks. A communication network may be provided linking the computer with equipment and appliances having a microprocessor based controller capable of communicating with the system. In one embodiment, the system automatically verifies the performance of equipment-related manual tasks in food preparation. In another embodiment, the system schedules the maintenance of a plurality of kitchen appliances. In another embodiment, the system provides a hold timer for tracking the hold time of cooked food products and determines when the hold time elapses. In yet another embodiment, the system manages the inventory of cooked food products in a food preparation establishment.

Compositions and methods are provided for modulating the growth, development and repair of bone, cartilage or other connective tissue. Devices and stimulus waveforms are provided to differentially modulate the behavior of osteoblasts, chondrocytes and other connective tissue cells to promote proliferation, differentiation, matrix formation or mineralization for in vitro or in vivo applications. Continuous-mode and pulse-burst-mode stimulation of cells with charge-balanced signals may be used. Bone, cartilage and other connective tissue growth is stimulated in part by nitric oxide release through electrical stimulation and may be modulated through co-administration of NO donors and NO synthase inhibitors. Bone, cartilage and other connective tissue growth is stimulated in part by release of BMP-2 and BMP-7 in response to electrical stimulation to promote differentiation of cells. The methods and devices described are useful in promoting repair of bone fractures, cartilage and connective tissue repair as well as for engineering tissue for transplantation.

A display substrate includes a signal line formed on a substrate, a connection pad receiving a driving signal from the signal line, at least one repair line formed along an outer periphery of the substrate, a first auxiliary repair line overlapping the signal fine at a first position with an insulating layer disposed therebetween, a second auxiliary repair line overlapping the signal line at a second position with the insulating layer disposed therebetween, and a connection line connecting the second auxiliary repair fine to the at least one repair line.

A prosthesis for implantation into a human body is made by a method that includes the steps of providing a natural animal ligament or tendon that has a substrate, crosslinking and fixing the substrate, minimizing the antigens from the substrate, tanning the substrate to improve its mechanical properties, and coupling an active layer to the substrate.

A method for treating an osteochondral defect or a chondral defect in a subject includes implanting a composite in a site of the osteochondral or chondral defect. The composite includes a hyaluronic acid derivative; and at least one member of the group consisting of a cell, a cellular growth factor and a cellular differentiation factor, which is impregnated in, or coupled to, the hyaluronic acid derivative. In one embodiment, carboxyl functionalities of the hyaluronic acid derivative are each independently derivatized to include an N-acylurea or O-acyl isourea, or both N-acylurea and O-acyl isourea. In another embodiment, the hyaluronic acid derivative is prepared by reacting an uncrosslinked hyaluronic acid with a biscarbodimide in the presence of a pH buffer in a range of between about 4 and about 8. The composite can be used for regenerating or stimulating regeneration of meniscal tissues in a subject in need thereof.

Compositions and methods for treating cardiovascular and pulmonary diseases and disorders with apelin are disclosed. In particular, the invention relates to formulations comprising apelin encapsulated in liposome nanocarriers conjugated with polyethylene glycol (PEG) and their use in treatment of cardiovascular and pulmonary diseases and disorders. Encapsulation of apelin in PEG-conjugated liposomes significantly enhances efficacy, improves cellular uptake of apelin, and allows for sustained and extended release of apelin under physiological conditions.

One embodiment of the present invention includes a surgical instrument including an instrument body including a shaft having a distal end, a proximal end and a length therebetween; and a bushing having a length, wherein at least a portion of the length of the bushing includes a spring portion including a resilient member, wherein the bushing is cannulated such that the shaft of the instrument is positioned there through.

Methods and compositions for treating hyperglycemia and pancreatic damage as well as stimulating the repair or regeneration of islet cells are disclosed.

Systems and methods are disclosed for establishing one or more personal guarantor(s); establishing one or more business entities; establishing a professional business presence; reporting the professional business presence and the one or more personal guarantors to one or more credit scoring companies; establishing a PAYDEX score of said one or more business entities to a minimum of 80 resulting in an applicant's ability to obtain a larger credit line and at more favorable contract terms determined by one or more credit line providers reviewing external data. Another embodiment includes a method for establishing at least one high credit line credit accounts of one or more business entities with an open trade account of $10,000 or higher maintained in good standing and reporting said trade accounts(s) to the business credit scoring agencies.

The invention discloses a solid microbial inoculum that is used for decomposing petroleum pollutants and petroleum products, and a preparation method and applications of the solid microbial inoculum; and the invention belongs to the technical field of biological reparation in the emergency processing of accidents including petroleum pollution of soils and petroleum product leakage. The solid microbial inoculum is prepared by mixing a pseudomonas aeruginosa bacteria fermented fluid, turfy soil and bran with proportion by weight: 0.1-1:1:0.2-0.5, and the effective living bacteria number of pseudomonas aeruginosa bacteria inside the pseudomonas aeruginosa bacteria fermented fluid is 10 to 10 in each milliliter. The solid microbial inoculum has the advantages of high liveness in soil and quick growth, does not cause secondary environmental pollution, and can be used in the biological reparation on the spot of accidents including petroleum pollution of soils and petroleum product leakage.

The invention discloses an external Chinese medicine for treating bedsore. The external Chinese medicine is prepared from moschus, dragon bone, myrrh, minium, bee wax, dried alum, pseudo-ginseng root, dragon's blood, suberect spatholobus stem, szechuan lovage rhizome, red-rooted salvia root, common clubmoss herb, honeysuckle flower, safflower, weeping forsythia, dahurian angelica root, fried pangolin, fried spina gleditsiae, thunberg fritillary bulb, sinkiang arnebia root, pepper, liquoric root, crude fructus gardenia, amur corktree bark, astragalus, coptis root, baikal skullcap root, garden burnet root, frankincense, borneol, pearl powder, sesame oil, common bletilla tuber, Japanese ampelopsis root and white paeony root in a certain ratio. The external Chinese medicine for treating bedsore can play roles in diminishing inflammation and sterilizing, and can be used for prompting convergence of bedsore surfaces and rapid regression of redness and swelling till bedsore surfaces are fully cured.

A compression plate kit that allows for manual compression of a bone discontinuity includes a bone plate, two or more reduction screws, and a compression clamp. The compression clamp can include engagement members configured to engage the reduction screws, thereby allowing a practitioner to compress a bone discontinuity by manually closing the compression clamp. One or more implementations of a kit of the present invention can provide a practitioner with physical or tactile feedback during the compression of a bone discontinuity, and thus, provide the practitioner with the ability to better control the compression and spacing of bone portions during a reduction.

A method for determining a root cause of a problem in a multiple-element system includes correlating an incoming alarm signal with an element x in a multiple-element system and accessing an implication list comprising a list of all elements upstream of element x. At least one element on the implication list is weighted with data relating to the at least one element. Taking into account the weighting step, a probability is calculated that an element on the implication list comprises a most-probable root cause of the subsequent alarm signal. The identified most-probable root cause of the incoming alarm signal is output.