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406results about How to "Shrink tumor" patented technology

Method of optimizing radiosurgery and radiotherapy with metalloporphyrins

An apparatus and method for subsequent optimization of radiosurgery and radiotherapy is provided. The invention includes administering a metalloporphyrin to the patient, and then creating a 3-dimensional mapping of tissue through use of PET or SPECT. Malignant and pre-malignant tissue has an affinity for the metalloporphyrin. During treatment, real-time images are also provided which are compared to the previous 3-dimensional mapping. Creation of the real-time images is also achieved through PET or SPECT wherein a metalloporphyrin is administered to the patient. Total administration of radiation is calculated by summing radiation from the metalloporphyrins and from the radiosurgery / radiotherapy. The amount of radiation delivered by the metalloporphyrins and by the radiosurgery / radiotherapy are adjustable based on a patient's response to the dual delivery.
Owner:ADAIR

Tea catechins in sustained release formulations as cancer specific proliferation inhibitors

InactiveUS6410052B1Potent therapeutic effectReduce adverse effect on normal ,BiocideHydroxy compound active ingredientsUnknown primaryDietary product
The invention described herein encompasses a methods and compositions of treating cancer or solid tumors comprising the administration of a therapeutically effective amount of catechins, a group of polyphenols found in green tea, to a mammal in need of such therapy. Compositions of catechins include but not limited to, epigallocatechin gallate (EGCg), epicatechin (EC), epicatechin gallate (ECG), epigallocatechin (EGC). The unique compositions of the invention contain various combinations of the catechins, alone or in combination with each other or other therapeutic agents and are used to treat primary and metastatic cancers in humans. The invention also encompasses the varying modes of administration of the therapeutic compounds, including a sustained release formulation which may be used as a therapeutic compound for the treatment of cancer or as a dietary supplement for the prevention of cancer.
Owner:PURDUE RES FOUND INC +1

Cancer markers and methods of use thereof

ActiveUS20160274121A1Reduce tumor sizeProlongation of survivalCompound screeningApoptosis detectionCellular biomarkersGlobulin
The present disclosure relates to methods and compositions which can modulate the globoseries glycosphingolipid synthesis. Particularly, the present disclosure is directed to glycoenzyme inhibitor compound and compositions and methods of use thereof that can modulate the synthesis of globoseries glycosphingolipid SSEA-3 / SSEA-4 / GloboH in the biosynthetic pathway; particularly, the glycoenzyme inhibitors target the alpha-4GalT; beta-4GalNAcT-I; or beta-3GalT-V enzymes in the globoseries synthetic pathway. Additionally, the present disclosure is also directed to vaccines, antibodies, and / or immunogenic conjugate compositions targeting the SSEA-3 / SSEA-4 / GLOBO H associated epitopes (natural and modified) which elicit antibodies and / or binding fragment production useful for modulating the globoseries glycosphingolipid synthesis. Moreover, the present disclosure is also directed to the method of using the compositions described herein for the treatment or detection of hyperproliferative diseases and / or conditions. Furthermore, the instant disclosure also relates to cancer stem cell biomarkers for disgnostic and therapeutic uses.
Owner:ACAD SINIC
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