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Preparation method of tilapia skin collagen composite recycled fiber repair material

A technology for composite regeneration and repair materials, applied in the fields of fiber chemical characteristics, single-component cellulose artificial filament, medical science, etc., can solve the problem of tissue repair ability and drug adhesion that need to be further improved, and the uniformity and stability of the composite film Poor resistance and other problems, to achieve the effect of excellent degradability, good adhesion, and increase porosity

Inactive Publication Date: 2017-09-15
HEFEI CHUANGWO TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, most of the existing technologies use regenerated cellulose and other materials to blend and freeze-dry to prepare composite films. The uniformity and stability of the composite films prepared by this method are poor, and the tissue repair ability and drug adhesion need to be further improved.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] A preparation method of tilapia skin collagen composite regenerated fiber repair material, comprising the following steps:

[0028] Step 1: The tilapia skin is descaled, rinsed repeatedly with deionized water, and the surface moisture is blotted with filter paper, and the tilapia skin is degreased with lipase. The degreased fish skin is soaked in 0.1mol / L NaOH to remove impurities, and then Wash the fish skin repeatedly with deionized water until the washing solution is neutral;

[0029] Step 2: Add the fish skin treated in step 1 into lactic acid solution at 4°C, pH 2.3, mass concentration 80%, the ratio of solid to liquid is 1:20, after fully extracting for 12 hours, centrifuge at 4°C and 5000r / min Treat for 40 minutes, take the supernatant, add NaCl to 0.9mol / L, salt out for 10 hours, after the collagen precipitates, centrifuge at 4°C, 5000r / min for 20 minutes, take the precipitate, and discard the supernatant;

[0030] Step 3: Redissolve the precipitate in 0.1mol / L...

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PUM

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Abstract

The invention relates to a preparation method of a tilapia skin collagen composite recycled fiber repair material, and belongs to the technical field of tissue repair material preparation, wherein the preparation method comprises: preparing tilapia skin collagen, preparing a bamboo fiber solution, preparing a recycled cellulose spinning liquid, and carrying out electrospinning to prepare the repair material. The prepared tissue repair material of the present invention has advantages of good antibacterial property, good mechanical property, good tissue repair property, and good drug adhesion.

Description

technical field [0001] The invention belongs to the technical field of preparation of tissue repair materials, and in particular relates to a preparation method of a tilapia skin collagen composite regenerated fiber repair material. Background technique [0002] As a natural biopolymer, cellulose has biodegradability, biocompatibility and unique physical, chemical and mechanical properties, and has become a research hotspot in the field of new biomedical materials. However, most of the existing technologies use regenerated cellulose and other materials to blend and freeze-dry to prepare composite films. The uniformity and stability of the composite films prepared by this method are poor, and the tissue repair ability and drug adhesion need to be further improved. . Contents of the invention [0003] In order to solve the problems in the prior art, the present invention provides a preparation method of tilapia skin collagen composite regenerated fiber repair material with ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L27/24A61L27/20A61L27/54A61L27/56A61L27/58D01F1/10D01F2/00
CPCA61L27/24A61L27/20A61L27/54A61L27/56A61L27/58A61L2300/232A61L2300/252A61L2300/404A61L2300/412A61L2300/604D01F1/10D01F2/00C08L89/00C08L1/02
Inventor 王吉鹏
Owner HEFEI CHUANGWO TECH CO LTD
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