The invention provides ginseng water energizing cream and a preparation method thereof, and also relates to a mask containing the ginseng water energizing cream, as well as application of the ginseng water energizing cream in production of anti-wrinkle preparations. The ginseng water energizing cream comprises ginseng root extract serving as a skin conditioner, a ginseng tissue culture, rosa canina fruit oil, grape seed oil, simmondsia chinensis seed oil, butyrspermum parkii, beta-glucan and ginseng seed oil, as well as a wetting agent, a thickening agent, an emulsifier, a preservative and water. The ginseng water energizing cream can achieve the effects of effectively increasing collagens, preventing skin aging, promoting skin compaction and elasticity, preventing wrinkles and effectively eliminating facial wrinkles, such as frown lines, nasolabial folds, Corners of wrinkle, and wrinkles on forehead. Therefore, the ginseng water energizing cream has an obvious skin care effect and is huge in predictable market potential and wide in application prospects.